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Results: 1-25 |
Results: 25

Authors: Cicero, DO Barbato, G Koch, U Ingallinella, P Bianchi, E Sambucini, S Neddermann, P De Francesco, R Pessi, A Bazzo, R
Citation: Do. Cicero et al., Measurement of homonuclear three-bond J((HH alpha)-H-N) coupling constantsin unlabeled peptides complexed with labeled proteins: Application to a decapeptide inhibitor bound to the proteinase domain of the NS3 protein of hepatitis C virus (HCV), J BIOM NMR, 20(1), 2001, pp. 23-29

Authors: De Francesco, R Neddermann, P Tomei, L Steinkuhler, C Gallinari, P Folgori, A
Citation: R. De Francesco et al., Biochemical and immunologic properties of the nonstructural proteins of the hepatitis C virus: Implications for development of antiviral agents and vaccines, SEM LIV DIS, 20(1), 2000, pp. 69-83

Authors: Barbato, G Cicero, DO Cordier, F Narjes, F Gerlach, B Sambucini, S Grzesiek, S Matassa, VG De Francesco, R Bazzo, R
Citation: G. Barbato et al., Inhibitor binding induces active site stabilization of the HCVNS3 protein serine protease domain, EMBO J, 19(6), 2000, pp. 1195-1206

Authors: De Francesco, R Steinkuhler, C
Citation: R. De Francesco et C. Steinkuhler, Structure and function of the hepatitis C virus NS3-NS4A serine proteinase, CURR T MICR, 242, 2000, pp. 149-169

Authors: Paolini, C Lahm, A De Francesco, R Gallinari, P
Citation: C. Paolini et al., Mutational analysis of hepatitis C virus NS3-associated helicase, J GEN VIROL, 81, 2000, pp. 1649-1658

Authors: Paolini, C De Francesco, R Gallinari, P
Citation: C. Paolini et al., Enzymatic properties of hepatitis C virus NS3-associated helicase, J GEN VIROL, 81, 2000, pp. 1335-1345

Authors: Tomei, L Vitale, RL Incitti, I Serafini, S Altamura, S Vitelli, A De Francesco, R
Citation: L. Tomei et al., Biochemical characterization of a hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence, J GEN VIROL, 81, 2000, pp. 759-767

Authors: Fattori, D Urbani, A Brunetti, M Ingenito, R Pessi, A Prendergast, K Narjes, F Matassa, VG De Francesco, R Steinkuhler, C
Citation: D. Fattori et al., Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer, J BIOL CHEM, 275(20), 2000, pp. 15106-15113

Authors: Di Marco, S Rizzi, M Volpari, C Walsh, MA Narjes, F Colarusso, S De Francesco, R Matassa, VG Sollazzo, M
Citation: S. Di Marco et al., Inhibition of the hepatitis C virus NS3/4A protease - The crystal structures of two protease-inhibitor complexes, J BIOL CHEM, 275(10), 2000, pp. 7152-7157

Authors: Narjes, F Brunetti, M Colarusso, S Gerlach, B Koch, U Biasiol, G Fattori, D De Francesco, R Matassa, VG Steinkuhler, C
Citation: F. Narjes et al., alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease, BIOCHEM, 39(7), 2000, pp. 1849-1861

Authors: De Francesco, R Pessi, A Steinkuhler, C
Citation: R. De Francesco et al., Mechanisms of hepatitis C virus NS3 proteinase inhibitors, J VIRAL HEP, 6, 1999, pp. 23-30

Authors: Orru, S Dal Piaz, F Casbarra, A Biasiol, G De Francesco, R Steinkuhler, C Pucci, P
Citation: S. Orru et al., Conformational changes in the NS3 protease from hepatitis C virus strain Bk monitored by limited proteolysis and mass spectrometry, PROTEIN SCI, 8(7), 1999, pp. 1445-1454

Authors: Martin, F Steinkuhler, C Brunetti, M Pessi, A Cortese, R De Francesco, R Sollazzo, M
Citation: F. Martin et al., A loop-mimetic inhibitor of the HCV-NS3 protease derived from a minibody, PROTEIN ENG, 12(11), 1999, pp. 1005-1011

Authors: Marcellin, P Alberti, A Dusheiko, G Esteban, R Manns, M Shouval, D Weiland, O Williams, R Benhamou, JP Rodes, J Alter, H Bismuth, H Desmet, V Guardia, J Heathcote, J Lok, A Maddrey, WC Zum Buschenfelde, KHM Pagliaro, L Paumgartner, G Sherlock, S Abrignani, S Alberti, A Alter, M Bonino, F Bortolotti, F Brechot, C de Moura, MC Carreno, V Colombo, M Craxi, A Davis, G De Francesco, R Degos, F Di Bisceglie, A Dienes, H Dusheiko, G Esteban, J Esteban, R Farci, P Ferrari, C Foster, G Hadziyannis, S Hoofnagle, J Koff, R Lavanchy, D Lindsay, K Lunel, F Manns, M Marcellin, P Mondelli, M Nalpas, B Naoumov, N Pawlotsky, JM Pol, S Pontisso, P Poynard, T Prieto, J Rizzetto, M Roggendorf, M Moreno, MR Samuel, D Sanchez-Tapias, J Schalm, S Shouval, D Simmonds, P Soriano, V Tassopoulos, N Thomas, H Trepo, C Van der Poel, CL Vogel, W Weiland, O Wejstal, R Williams, R Wright, T Zanetti, A Zarski, JP Zeuzem, S Zoulim, F
Citation: P. Marcellin et al., EASL International Consensus Conference on Hepatitis C - Paris, 26-27 February 1999 - Consensus statement (Reprinted from Journal of Hematology, vol 30, pg 956-961, 1999), J HEPATOL, 31, 1999, pp. 3-8

Authors: De Francesco, R
Citation: R. De Francesco, Molecular virology of the hepatitis C virus, J HEPATOL, 31, 1999, pp. 47-53

Authors: Bressanelli, S Tomei, L Roussel, A Incitti, I Vitale, RL Mathieu, M De Francesco, R Rey, FA
Citation: S. Bressanelli et al., Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus, P NAS US, 96(23), 1999, pp. 13034-13039

Authors: Neddermann, P Clementi, A De Francesco, R
Citation: P. Neddermann et al., Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein, J VIROLOGY, 73(12), 1999, pp. 9984-9991

Authors: Filocamo, G Pacini, L Nardi, C Bartholomew, L Scaturro, M Delmastro, P Tramontano, A De Francesco, R Migliaccio, G
Citation: G. Filocamo et al., Selection of functional variants of the NS3-NS4A protease of hepatitis C virus by using chimeric sindbis viruses, J VIROLOGY, 73(1), 1999, pp. 561-575

Authors: Barbato, G Cicero, DO Nardi, MC Steinkuhler, C Cortese, R De Francesco, R Bazzo, R
Citation: G. Barbato et al., The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism, J MOL BIOL, 289(2), 1999, pp. 371-384

Authors: Cicero, DO Barbato, G Koch, U Ingallinella, P Bianchi, E Nardi, MC Steinkuhler, C Cortese, R Matassa, V De Francesco, R Pessi, A Bazzo, R
Citation: Do. Cicero et al., Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies, J MOL BIOL, 289(2), 1999, pp. 385-396

Authors: Gallinari, P Paolini, C Brennan, D Nardi, C Steinkuhler, C De Francesco, R
Citation: P. Gallinari et al., Modulation of hepatitis C virus NS3 protease and helicase activities through the interaction with NS4A, BIOCHEM, 38(17), 1999, pp. 5620-5632

Authors: Urbani, A Biasiol, G Brunetti, M Volpari, C Di Marco, S Sollazzo, M Orru, S Dal Piaz, F Casbarra, A Pucci, P Nardi, C Gallinari, P De Francesco, R Steinkuhler, C
Citation: A. Urbani et al., Multiple determinants influence complex formation of the hepatitis C virusNS3 protease domain with ils NS4A cofactor peptide, BIOCHEM, 38(16), 1999, pp. 5206-5215

Authors: Cerretani, N Di Renzo, L Serafini, S Vitelli, A Gennari, N Bianchi, E Pessi, A Urbani, A Colloca, S De Francesco, R Steinkuhler, C Altamura, S
Citation: N. Cerretani et al., A high-throughput radiometric assay for hepatitis C virus NS3 protease, ANALYT BIOC, 266(2), 1999, pp. 192-197

Authors: Pasquo, A Nardi, MC Dimasi, N Tomei, L Steinkuhler, C Delmastro, P Tramontano, A De Francesco, R
Citation: A. Pasquo et al., Rational design and functional expression of a constitutively active single-chain NS4A-NS3 proteinase, FOLD DES, 3(6), 1998, pp. 433-441

Authors: De Francesco, R Pessi, A Steinkuhler, C
Citation: R. De Francesco et al., The hepatitis C virus NS3 proteinase: structure and function of a zinc-containing serine proteinase, THERAPIES FOR VIRAL HEPATITIS, 1998, pp. 235-245
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