Authors:
Degreve, B
Esnouf, R
De Clercq, E
Balzarini, J
Citation: B. Degreve et al., Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase, MOLEC PHARM, 59(2), 2001, pp. 285-293
Authors:
Balzarini, J
Degreve, B
Zhu, CY
Durini, E
Porcu, L
De Clercq, E
Karlsson, A
Manfredini, S
Citation: J. Balzarini et al., 2 '-O-acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of humanmitochondrial thymidine kinase, BIOCH PHARM, 61(6), 2001, pp. 727-732
Citation: B. Degreve et al., Selection of HSV-1 TK gene-transfected murine mammary carcinoma coils resistant to (E)-5-(2-bromovinyl)-2 '-deoxyuridine (BVDU) and ganciclovir (GCV), GENE THER, 7(18), 2000, pp. 1543-1552
Authors:
Grignet-Debrus, C
Cool, V
Baudson, N
Degreve, B
Balzarini, J
De Leval, L
Debrus, S
Velu, T
Calberg-Bacq, CM
Citation: C. Grignet-debrus et al., Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2 '-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressingeither the Varicella zoster or the Herpes simplex virus thymidine kinase, CANC GENE T, 7(2), 2000, pp. 215-223
Authors:
Degreve, B
Esnouf, R
De Clercq, E
Balzarini, J
Citation: B. Degreve et al., Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of Alanine-167 to tyrosine, MOLEC PHARM, 58(6), 2000, pp. 1326-1332
Authors:
Balzarini, J
Degreve, B
Hatse, S
De Clercq, E
Breuer, M
Johansson, M
Huybrechts, R
Karlsson, A
Citation: J. Balzarini et al., The multifunctional deoxynucleoside kinase of insect cells is a target forthe development of new insecticides, MOLEC PHARM, 57(4), 2000, pp. 811-819
Authors:
Balzarini, J
Degreve, B
Esteban-Gamboa, A
Esnouf, R
De Clercq, E
Engelborghs, Y
Camarasa, MJ
Perez-Perez, MJ
Citation: J. Balzarini et al., Kinetic analysis of novel multisubstrate analogue inhibitors of thymidine phosphorylase, FEBS LETTER, 483(2-3), 2000, pp. 181-185
Citation: B. Degreve et al., Bystander effect of purine nucleoside analogues in HSV-1tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues, GENE THER, 6(2), 1999, pp. 162-170
Authors:
Wera, S
Degreve, B
Balzarini, J
De Clercq, E
Thevelein, JM
Neyts, J
Citation: S. Wera et al., Budding yeast as a screening tool for discovery of nucleoside analogs for use in HSV-1 TK suicide-gene therapy, BIOTECHNIQU, 27(4), 1999, pp. 772
Authors:
Johansson, M
Van Rompay, AR
Degreve, B
Balzarini, J
Karlsson, A
Citation: M. Johansson et al., Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster, J BIOL CHEM, 274(34), 1999, pp. 23814-23819
Authors:
Degreve, B
Esnouf, R
De Clercq, E
Balzarini, J
Citation: B. Degreve et al., Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase, BIOC BIOP R, 264(2), 1999, pp. 338-342