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Results: 1-21 |
Results: 21
Synthesis and antiviral activity of methylenedifluorocyclopropane analogues of nucleosides
Authors: Wang, R Ksebati, MB Drach, JC Zemlicka, J
Citation: R. Wang et al., Synthesis and antiviral activity of methylenedifluorocyclopropane analogues of nucleosides, NUCLEOS NUC, 20(4-7), 2001, pp. 329-332
Methylene-gem-difluorocyclopropane analogues of nucleosides: Synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity
Authors: Wang, RF Ksebati, MB Corbett, TH Kern, ER Drach, JC Zemlicka, J
Citation: Rf. Wang et al., Methylene-gem-difluorocyclopropane analogues of nucleosides: Synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity, J MED CHEM, 44(23), 2001, pp. 4019-4022
Synthesis of 4-substituted imidazo[4,5-d][1,2,3]triazine (2-azapurine)nucleosides
Authors: Krawczyk, S Migawa, MT Drach, JC Townsend, LB
Citation: S. Krawczyk et al., Synthesis of 4-substituted imidazo[4,5-d][1,2,3]triazine (2-azapurine)nucleosides, NUCLEOS NUC, 19(1-2), 2000, pp. 39-68
Synthesis and evaluation of a series of 2 '-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94)
Authors: Chan, JH Chamberlain, SD Biron, KK Davis, MG Harvey, RJ Selleseth, DW Dornsife, RE Dark, EH Frick, LW Townsend, LB Drach, JC Koszalka, GW
Citation: Jh. Chan et al., Synthesis and evaluation of a series of 2 '-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94), NUCLEOS NUC, 19(1-2), 2000, pp. 101-123
Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections
Authors: Zou, RM Kawashima, E Freeman, GA Koszalke, GW Drach, JC Townsend, LB
Citation: Rm. Zou et al., Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections, NUCLEOS NUC, 19(1-2), 2000, pp. 125-153
Differences in DNA packaging genes and sensitivity to benzimidazole ribonucleosides between human cytomegalovirus strains AD169 and Towne
Authors: Krosky, PM Ptak, RG Underwood, MR Biron, KK Townsend, LB Drach, JC
Citation: Pm. Krosky et al., Differences in DNA packaging genes and sensitivity to benzimidazole ribonucleosides between human cytomegalovirus strains AD169 and Towne, ANTIVIR CHE, 11(5), 2000, pp. 349-352
Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninateprodrugs: influence of heterocyclic base, type of virus and host cells
Authors: Qiu, YL Geiser, F Kira, T Gullen, E Cheng, YC Ptak, RG Breitenbach, JM Drach, JC Hartline, CB Kern, ER Zemlicka, J
Citation: Yl. Qiu et al., Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninateprodrugs: influence of heterocyclic base, type of virus and host cells, ANTIVIR CHE, 11(3), 2000, pp. 191-202
Spiropentane mimics of nucleosides: Analogues of 2 '-deoxyadenosine and 2 '-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity
Authors: Guan, HP Ksebati, MB Cheng, YC Drach, JC Kern, ER Zemlicka, J
Citation: Hp. Guan et al., Spiropentane mimics of nucleosides: Analogues of 2 '-deoxyadenosine and 2 '-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity, J ORG CHEM, 65(5), 2000, pp. 1280-1290
Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides
Authors: Zhu, ZJ Lippa, B Drach, JC Townsend, LB
Citation: Zj. Zhu et al., Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides, J MED CHEM, 43(12), 2000, pp. 2430-2437
Deoxy sugar analogues of triciribine: Correlation of antiviral and antiproliferative activity with intracellular phosphorylation
Authors: Porcari, AR Ptak, RG Borysko, KZ Breitenbach, JM Vittori, S Wotring, LL Drach, JC Townsend, LB
Citation: Ar. Porcari et al., Deoxy sugar analogues of triciribine: Correlation of antiviral and antiproliferative activity with intracellular phosphorylation, J MED CHEM, 43(12), 2000, pp. 2438-2448
Synthesis and antiviral evaluation of trisubstituted indole N-nucleosides as analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB)
Authors: Chen, JJ Wei, Y Drach, JC Townsend, LB
Citation: Jj. Chen et al., Synthesis and antiviral evaluation of trisubstituted indole N-nucleosides as analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB), J MED CHEM, 43(12), 2000, pp. 2449-2456
6-N-acyltriciribine analogues: Structure-activity relationship between acyl carbon chain length and activity against HIV-1
Authors: Porcari, AR Ptak, RG Borysko, KZ Breitenbach, JM Drach, JC Townsend, LB
Citation: Ar. Porcari et al., 6-N-acyltriciribine analogues: Structure-activity relationship between acyl carbon chain length and activity against HIV-1, J MED CHEM, 43(12), 2000, pp. 2457-2463
Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles
Authors: Gudmundsson, KS Tidwell, J Lippa, N Koszalka, GW van Draanen, N Ptak, RG Drach, JC Townsend, LB
Citation: Ks. Gudmundsson et al., Synthesis and antiviral evaluation of halogenated beta-D- and -L-erythrofuranosylbenzimidazoles, J MED CHEM, 43(12), 2000, pp. 2464-2472
Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability
Authors: Gudmundsson, KS Freeman, GA Drach, JC Townsend, LB
Citation: Ks. Gudmundsson et al., Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability, J MED CHEM, 43(12), 2000, pp. 2473-2478
Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB
Authors: Townsend, LB Gudmundsson, KS Daluge, SM Chen, JJ Zhu, ZJ Koszalka, GW Boyd, L Chamberlain, SD Freeman, GA Biron, KK Drach, JC
Citation: Lb. Townsend et al., Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB, NUCLEOS NUC, 18(4-5), 1999, pp. 509-519
Methylenecyclopropane analogues of nucleosides: Synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol
Authors: Qiu, YL Hempel, A Camerman, N Camerman, A Geiser, F Ptak, RG Breitenbach, JM Kira, T Li, L Gullen, E Cheng, YC Drach, JC Zemlicka, J
Citation: Yl. Qiu et al., Methylenecyclopropane analogues of nucleosides: Synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol, NUCLEOS NUC, 18(4-5), 1999, pp. 597-598
Synthesis and antiviral activity of novel aza-acyclonucleosides
Authors: Bergmeier, SC Fundy, SL Drach, JC
Citation: Sc. Bergmeier et al., Synthesis and antiviral activity of novel aza-acyclonucleosides, NUCLEOS NUC, 18(2), 1999, pp. 227-238
Acyclic sugar analogs of triciribine: Lack of antiviral and antiproliferative activity correlate with low intracellular phosphorylation
Authors: Porcari, AR Borysko, KZ Ptak, RG Breitenbach, JM Wotring, LL Drach, JC Townsend, LB
Citation: Ar. Porcari et al., Acyclic sugar analogs of triciribine: Lack of antiviral and antiproliferative activity correlate with low intracellular phosphorylation, NUCLEOS NUC, 18(11-12), 1999, pp. 2475-2497
Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides
Authors: Qiu, YL Ptak, RG Breitenbach, JM Lin, JS Cheng, YC Drach, JC Kern, ER Zemlicka, J
Citation: Yl. Qiu et al., Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides, ANTIVIR RES, 43(1), 1999, pp. 37-53
Nonnucleoside pyrrolopyrimidines with a unique mechanism of action againsthuman cytomegalovirus
Authors: Jacobson, JG Renau, TE Nassiri, MR Sweier, DG Breitenbach, JM Townsend, LB Drach, JC
Citation: Jg. Jacobson et al., Nonnucleoside pyrrolopyrimidines with a unique mechanism of action againsthuman cytomegalovirus, ANTIM AG CH, 43(8), 1999, pp. 1888-1894
(R)- and (S)-(+)-synadenol: Synthesis, absolute configuration, and enantioselectivity of antiviral effect
Authors: Qiu, YL Hempel, A Camerman, N Camerman, A Geiser, F Ptak, RG Breitenbach, JM Kira, T Li, L Gullen, E Cheng, YC Drach, JC Zemlicka, J
Citation: Yl. Qiu et al., (R)- and (S)-(+)-synadenol: Synthesis, absolute configuration, and enantioselectivity of antiviral effect, J MED CHEM, 41(26), 1998, pp. 5257-5264
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