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Results: 1-18 |
Results: 18
Application of in silico approaches to predicting drug-drug interactions
Authors: Ekins, S Wrighton, SA
Citation: S. Ekins et Sa. Wrighton, Application of in silico approaches to predicting drug-drug interactions, J PHARM TOX, 45(1), 2001, pp. 65-69
Three-dimensional quantitative structure-permeability relationship analysis for a series of inhibitors of rhinovirus replication
Authors: Ekins, S Durst, GL Stratford, RE Thorner, DA Lewis, R Loncharich, RJ Wikel, JH
Citation: S. Ekins et al., Three-dimensional quantitative structure-permeability relationship analysis for a series of inhibitors of rhinovirus replication, J CHEM INF, 41(6), 2001, pp. 1578-1586
Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome P450 active sites
Authors: Ekins, S De Groot, MJ Jones, JP
Citation: S. Ekins et al., Pharmacophore and three-dimensional quantitative structure activity relationship methods for modeling cytochrome P450 active sites, DRUG META D, 29(7), 2001, pp. 936-944
Progress in predicting human ADME parameters in silico
Authors: Ekins, S Waller, CL Swaan, PW Cruciani, G Wrighton, SA Wikel, JH
Citation: S. Ekins et al., Progress in predicting human ADME parameters in silico, J PHARM TOX, 44(1), 2000, pp. 251-272
Present and future in vitro approaches for drug metabolism
Authors: Ekins, S Ring, BJ Grace, J McRobie-Belle, DJ Wrighton, SA
Citation: S. Ekins et al., Present and future in vitro approaches for drug metabolism, J PHARM TOX, 44(1), 2000, pp. 313-324
Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors
Authors: Ekins, S Bravi, G Binkley, S Gillespie, JS Ring, BJ Wikel, JH Wrighton, SA
Citation: S. Ekins et al., Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors, DRUG META D, 28(8), 2000, pp. 994-1002
(R)-, (S)-, and racemic fluoxetine N-demethylation by human cytochrome P450 enzymes
Authors: Margolis, JM O'Donnell, JP Mankowski, DC Ekins, S Obach, RS
Citation: Jm. Margolis et al., (R)-, (S)-, and racemic fluoxetine N-demethylation by human cytochrome P450 enzymes, DRUG META D, 28(10), 2000, pp. 1187-1191
Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates
Authors: Mankowski, DC Lawton, MP Ekins, S
Citation: Dc. Mankowski et al., Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates, XENOBIOTICA, 30(8), 2000, pp. 745-754
Three-dimensional quantitative structure activity relationship computational approaches for prediction of human in vitro intrinsic clearance
Authors: Ekins, S Obach, RS
Citation: S. Ekins et Rs. Obach, Three-dimensional quantitative structure activity relationship computational approaches for prediction of human in vitro intrinsic clearance, J PHARM EXP, 295(2), 2000, pp. 463-473
Predicting drug-drug interactions in silico using pharmacophores: A paradigm for the next millennium
Authors: Ekins, S Ring, BJ Bravi, G Wikel, JH Wrighton, SA
Citation: S. Ekins et al., Predicting drug-drug interactions in silico using pharmacophores: A paradigm for the next millennium, IUL BIOTECH, 2, 2000, pp. 269-299
Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors
Authors: Ekins, S Bravi, G Binkley, S Gillespie, JS Ring, BJ Wikel, JH Wrighton, SA
Citation: S. Ekins et al., Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors, PHARMACOGEN, 9(4), 1999, pp. 477-489
The role of CYP2B6 in human xenobiotic metabolism
Authors: Ekins, S Wrighton, SA
Citation: S. Ekins et Sa. Wrighton, The role of CYP2B6 in human xenobiotic metabolism, DRUG METAB, 31(3), 1999, pp. 719-754
Three-dimensional-quantitative structure activity relationship analysis ofcytochrome P-450 3A4 substrates
Authors: Ekins, S Bravi, G Wikel, JH Wrighton, SA
Citation: S. Ekins et al., Three-dimensional-quantitative structure activity relationship analysis ofcytochrome P-450 3A4 substrates, J PHARM EXP, 291(1), 1999, pp. 424-433
Three- and four-dimensional quantitative structure activity relationship analyses of cytochrome P-450 3A4 inhibitors
Authors: Ekins, S Bravi, G Binkley, S Gillespie, JS Ring, BJ Wikel, JH Wrighton, SA
Citation: S. Ekins et al., Three- and four-dimensional quantitative structure activity relationship analyses of cytochrome P-450 3A4 inhibitors, J PHARM EXP, 290(1), 1999, pp. 429-438
Three-dimensional quantitative structure activity relationship analyses ofsubstrates for CYP2B6
Authors: Ekins, S Bravi, G Ring, BJ Gillespie, TA Gillespie, JS Vandenbranden, M Wrighton, SA Wikel, JH
Citation: S. Ekins et al., Three-dimensional quantitative structure activity relationship analyses ofsubstrates for CYP2B6, J PHARM EXP, 288(1), 1999, pp. 21-29
Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver
Authors: Mankowski, DC Laddison, KJ Christopherson, PA Ekins, S Tweedie, DJ Lawton, MP
Citation: Dc. Mankowski et al., Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver, ARCH BIOCH, 372(1), 1999, pp. 189-196
In vitro metabolism: Subcellular fractions
Authors: Ekins, S Maenpaa, J Wrighton, SA
Citation: S. Ekins et al., In vitro metabolism: Subcellular fractions, HANDBOOK OF DRUG METABOLISM, 1999, pp. 363-399
Autoactivation and activation of the cytochrome P450s
Authors: Ekins, S Ring, BJ Binkley, SN Hall, SD Wrighton, SA
Citation: S. Ekins et al., Autoactivation and activation of the cytochrome P450s, INT J CL PH, 36(12), 1998, pp. 642-651
Risultati: 1-18 |