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Results: 1-20 |
Results: 20
SOME 6-AZA-5-SUBSTITUTED-2'-DEOXYURIDINES SHOW POTENT AND SELECTIVE-INHIBITION OF HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE
Authors: BASNAK I SUN M HAMOR TA FOCHER F VERRI A SPADARI S WROBLOWSKI B HERDEWIJN P WALKER RT
Citation: I. Basnak et al., SOME 6-AZA-5-SUBSTITUTED-2'-DEOXYURIDINES SHOW POTENT AND SELECTIVE-INHIBITION OF HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE, Nucleosides & nucleotides, 17(1-3), 1998, pp. 187-206
TRICHOMONAS-VAGINALIS THYMIDINE KINASE - PURIFICATION, CHARACTERIZATION AND SEARCH FOR INHIBITORS
Authors: STROSSELLI S SPADARI S WALKER RT BASNAK I FOCHER F
Citation: S. Strosselli et al., TRICHOMONAS-VAGINALIS THYMIDINE KINASE - PURIFICATION, CHARACTERIZATION AND SEARCH FOR INHIBITORS, Biochemical journal, 334, 1998, pp. 15-22
RELAXED ENANTIOSELECTIVITY OF HUMAN MITOCHONDRIAL THYMIDINE KINASE AND CHEMOTHERAPEUTIC USES OF L-NUCLEOSIDE ANALOGS
Authors: VERRI A PRIORI G SPADARI S TONDELLI L FOCHER F
Citation: A. Verri et al., RELAXED ENANTIOSELECTIVITY OF HUMAN MITOCHONDRIAL THYMIDINE KINASE AND CHEMOTHERAPEUTIC USES OF L-NUCLEOSIDE ANALOGS, Biochemical journal, 328, 1997, pp. 317-320
LACK OF ENANTIOSPECIFICITY OF HUMAN 2'-DEOXYCYTIDINE KINASE - RELEVANCE FOR THE ACTIVATION OF BETA-L-DEOXYCYTIDINE ANALOGS AS ANTINEOPLASTIC AND ANTIVIRAL AGENTS
Authors: VERRI A FOCHER F PRIORI G GOSSELIN G IMBACH JL CAPOBIANCO M GARBESI A SPADARI S
Citation: A. Verri et al., LACK OF ENANTIOSPECIFICITY OF HUMAN 2'-DEOXYCYTIDINE KINASE - RELEVANCE FOR THE ACTIVATION OF BETA-L-DEOXYCYTIDINE ANALOGS AS ANTINEOPLASTIC AND ANTIVIRAL AGENTS, Molecular pharmacology, 51(1), 1997, pp. 132-138
N-2-(P-N-OCTYLPHENYL)DGTP - SYNTHESIS AND INHIBITORY ACTIVITY AGAINSTDNA-POLYMERASES
Authors: JANSONS J STATTEL J VERRI A GAMBINO J KHAN N FOCHER F SPADARI S WRIGHT G
Citation: J. Jansons et al., N-2-(P-N-OCTYLPHENYL)DGTP - SYNTHESIS AND INHIBITORY ACTIVITY AGAINSTDNA-POLYMERASES, Nucleosides & nucleotides, 15(1-3), 1996, pp. 669-682
9-(4-HYDROXYBUTYL)-N-2-PHENYLGUANINE (HBPG), A THYMIDINE KINASE INHIBITOR, SUPPRESSES HERPES-VIRUS REACTIVATION IN MICE
Authors: GEBHARDT BM WRIGHT GE XU HY FOCHER F SPADARI S KAUFMAN HE
Citation: Bm. Gebhardt et al., 9-(4-HYDROXYBUTYL)-N-2-PHENYLGUANINE (HBPG), A THYMIDINE KINASE INHIBITOR, SUPPRESSES HERPES-VIRUS REACTIVATION IN MICE, Antiviral research, 30(2-3), 1996, pp. 87-94
FURTHER STUDY OF THE MECHANISM UNDERLYING THE CELLULAR-RESISTANCE TO AZT
Authors: TURRIZIANI O ANTONELLI G FOCHER F BAMBACIONI F DIANZANI F
Citation: O. Turriziani et al., FURTHER STUDY OF THE MECHANISM UNDERLYING THE CELLULAR-RESISTANCE TO AZT, Biochemical and biophysical research communications, 228(3), 1996, pp. 797-801
LATE INDUCTION OF HUMAN DNA-LIGASE-I AFTER UV-C IRRADIATION
Authors: MONTECUCCO A SAVINI E BIAMONTI G STEFANINI M FOCHER F CIARROCCHI G
Citation: A. Montecucco et al., LATE INDUCTION OF HUMAN DNA-LIGASE-I AFTER UV-C IRRADIATION, Nucleic acids research, 23(6), 1995, pp. 962-966
STEREOSPECIFICITY OF HUMAN DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA,DNA-POLYMERASE-GAMMA, DNA-POLYMERASE-DELTA AND DNA-POLYMERASE-EPSILON, HIV-REVERSE TRANSCRIPTASE, HSV-1 DNA-POLYMERASE, CALF THYMUS TERMINAL TRANSFERASE AND ESCHERICHIA-COLI DNA-POLYMERASE-I IN RECOGNIZING D-THYMIDINE AND L-THYMIDINE 5'-TRIPHOSPHATE AS SUBSTRATE
Authors: FOCHER F MAGA G BENDISCIOLI A CAPOBIANCO W COLONNA F GARBESI A SPADARI S
Citation: F. Focher et al., STEREOSPECIFICITY OF HUMAN DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA,DNA-POLYMERASE-GAMMA, DNA-POLYMERASE-DELTA AND DNA-POLYMERASE-EPSILON, HIV-REVERSE TRANSCRIPTASE, HSV-1 DNA-POLYMERASE, CALF THYMUS TERMINAL TRANSFERASE AND ESCHERICHIA-COLI DNA-POLYMERASE-I IN RECOGNIZING D-THYMIDINE AND L-THYMIDINE 5'-TRIPHOSPHATE AS SUBSTRATE, Nucleic acids research, 23(15), 1995, pp. 2840-2847
LACK OF STEREOSPECIFICITY OF SOME CELLULAR AND VIRAL ENZYMES INVOLVEDIN THE SYNTHESIS OF DEOXYRIBONUCLEOTIDES AND DNA - MOLECULAR-BASIS FOR THE ANTIVIRAL ACTIVITY OF UNNATURAL L-BETA-NUCLEOSIDES
Authors: SPADARI S MAGA G VERRI A BENDISCIOLI A TONDELLI L CAPOBIANCO M COLONNA F GARBESI A FOCHER F
Citation: S. Spadari et al., LACK OF STEREOSPECIFICITY OF SOME CELLULAR AND VIRAL ENZYMES INVOLVEDIN THE SYNTHESIS OF DEOXYRIBONUCLEOTIDES AND DNA - MOLECULAR-BASIS FOR THE ANTIVIRAL ACTIVITY OF UNNATURAL L-BETA-NUCLEOSIDES, Biochimie, 77(11), 1995, pp. 861-867
HERPES-SIMPLEX VIRUS TYPE-1 (HSV-1) URACIL-DNA GLYCOSYLASE - FUNCTIONAL EXPRESSION IN ESCHERICHIA-COLI, BIOCHEMICAL-CHARACTERIZATION, AND SELECTIVE-INHIBITION BY 6-(P-N-OCTYLANILINO)URACIL
Authors: ARGNANI R FOCHER F ZUCCHINI S VERRI A WRIGHT GE SPADARI S MANSERVIGI R
Citation: R. Argnani et al., HERPES-SIMPLEX VIRUS TYPE-1 (HSV-1) URACIL-DNA GLYCOSYLASE - FUNCTIONAL EXPRESSION IN ESCHERICHIA-COLI, BIOCHEMICAL-CHARACTERIZATION, AND SELECTIVE-INHIBITION BY 6-(P-N-OCTYLANILINO)URACIL, Virology, 211(1), 1995, pp. 307-311
5-IODO-2'-DEOXY-L-URIDINE AND (E)-5-(2-BROMOVINYL)-2'-DEOXY-L-URIDINE- SELECTIVE PHOSPHORYLATION BY HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE, ANTIHERPETIC ACTIVITY, AND CYTOTOXICITY STUDIES
Authors: SPADARI S CIARROCCHI G FOCHER F VERRI A MAGA G ARCAMONE F IAFRATE E MANZINI S GARBESI A TONDELLI L
Citation: S. Spadari et al., 5-IODO-2'-DEOXY-L-URIDINE AND (E)-5-(2-BROMOVINYL)-2'-DEOXY-L-URIDINE- SELECTIVE PHOSPHORYLATION BY HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE, ANTIHERPETIC ACTIVITY, AND CYTOTOXICITY STUDIES, Molecular pharmacology, 47(6), 1995, pp. 1231-1238
SYNTHESIS, PROPERTIES, AND PHARMACOKINETIC STUDIES OF N-2-PHENYLGUANINE DERIVATIVES AS INHIBITORS OF HERPES-SIMPLEX VIRUS THYMIDINE KINASES
Authors: XU HY MAGA G FOCHER F SMITH ER SPADARI S GAMBINO J WRIGHT GE
Citation: Hy. Xu et al., SYNTHESIS, PROPERTIES, AND PHARMACOKINETIC STUDIES OF N-2-PHENYLGUANINE DERIVATIVES AS INHIBITORS OF HERPES-SIMPLEX VIRUS THYMIDINE KINASES, Journal of medicinal chemistry, 38(1), 1995, pp. 49-57
KINETIC-STUDIES WITH N-2-PHENYLGUANINES AND WITH L-THYMIDINE INDICATETHAT HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE AND THYMIDYLATE KINASE SHARE A COMMON ACTIVE-SITE
Authors: MAGA G FOCHER F WRIGHT GE CAPOBIANCO M GARBESI A BENDISCIOLI A SPADARI S
Citation: G. Maga et al., KINETIC-STUDIES WITH N-2-PHENYLGUANINES AND WITH L-THYMIDINE INDICATETHAT HERPES-SIMPLEX VIRUS TYPE-1 THYMIDINE KINASE AND THYMIDYLATE KINASE SHARE A COMMON ACTIVE-SITE, Biochemical journal, 302, 1994, pp. 279-282
IDENTIFICATION, PARTIAL-PURIFICATION AND INHIBITION BY GUANINE ANALOGS OF A NOVEL ENZYMATIC-ACTIVITY WHICH PHOSPHORYLATES GUANOSINE TO GMP IN THE PROTOZOAN PARASITE EIMERIA-TENELLA
Authors: MAGA G SPADARI S WRIGHT GE FOCHER F
Citation: G. Maga et al., IDENTIFICATION, PARTIAL-PURIFICATION AND INHIBITION BY GUANINE ANALOGS OF A NOVEL ENZYMATIC-ACTIVITY WHICH PHOSPHORYLATES GUANOSINE TO GMP IN THE PROTOZOAN PARASITE EIMERIA-TENELLA, Biochemical journal, 298, 1994, pp. 289-294
RESEARCHES ON ANTIVIRAL AGENTS .4. STUDIES ON THE CHEMISTRY OF 6-METHYL-2-METHOXY-4-O-ACYLOXY AND 6-METHYL-2,4-DI-O-ACYLOXYPYRIMIDINE DERIVATIVES AS NEW ACYLATION REAGENTS AND INHIBITORS OF URACIL DNA GLYCOSYLASES
Authors: BOTTA M SALADINO R GENTILE G SUMMA V NICOLETTI R VERRI A FOCHER F SPADARI S
Citation: M. Botta et al., RESEARCHES ON ANTIVIRAL AGENTS .4. STUDIES ON THE CHEMISTRY OF 6-METHYL-2-METHOXY-4-O-ACYLOXY AND 6-METHYL-2,4-DI-O-ACYLOXYPYRIMIDINE DERIVATIVES AS NEW ACYLATION REAGENTS AND INHIBITORS OF URACIL DNA GLYCOSYLASES, Tetrahedron, 50(11), 1994, pp. 3603-3618
INHIBITOR ANALYSIS OF CALF THYMUS DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA AND DNA-POLYMERASE-EPSILON
Authors: WRIGHT GE HUBSCHER U KHAN NN FOCHER F VERRI A
Citation: Ge. Wright et al., INHIBITOR ANALYSIS OF CALF THYMUS DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA AND DNA-POLYMERASE-EPSILON, FEBS letters, 341(1), 1994, pp. 128-130
LACK OF STEREOSPECIFICITY OF SUID PSEUDORABIES VIRUS THYMIDINE KINASE
Authors: MAGA G VERRI A BONIZZI L PONTI W POLI G GARBESI A NICCOLAI D SPADARI S FOCHER F
Citation: G. Maga et al., LACK OF STEREOSPECIFICITY OF SUID PSEUDORABIES VIRUS THYMIDINE KINASE, Biochemical journal, 294, 1993, pp. 381-385
HERPES-SIMPLEX VIRUS TYPE-1 URACIL-DNA GLYCOSYLASE - ISOLATION AND SELECTIVE-INHIBITION BY NOVEL URACIL DERIVATIVES
Authors: FOCHER F VERRI A SPADARI S MANSERVIGI R GAMBINO J WRIGHT GE
Citation: F. Focher et al., HERPES-SIMPLEX VIRUS TYPE-1 URACIL-DNA GLYCOSYLASE - ISOLATION AND SELECTIVE-INHIBITION BY NOVEL URACIL DERIVATIVES, Biochemical journal, 292, 1993, pp. 883-889
MYOCLONUS EPILEPSY AND RAGGED-RED FIBERS - BLOOD MITOCHONDRIAL-DNA HETEROPLASMY IN AFFECTED AND ASYMPTOMATIC MEMBERS OF A FAMILY
Authors: PICCOLO G FOCHER F VERRI A SPADARI S BANFI P GEROSA E MAZZARELLO P
Citation: G. Piccolo et al., MYOCLONUS EPILEPSY AND RAGGED-RED FIBERS - BLOOD MITOCHONDRIAL-DNA HETEROPLASMY IN AFFECTED AND ASYMPTOMATIC MEMBERS OF A FAMILY, Acta neurologica Scandinavica, 88(6), 1993, pp. 406-409
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