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Results: 1-25 | 26-27
Results: 1-25/27
Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4
Authors: Soni, R O'Reilly, T Furet, P Muller, L Stephan, C Zumstein-Mecker, S Fretz, H Fabbro, D Chaudhuri, B
Citation: R. Soni et al., Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4, J NAT CANC, 93(6), 2001, pp. 436
Expression and purification of human recombinant GST-FGF receptor-1
Authors: Homann, S Schacher, B Zumstein-Mecker, S Fabbro, D Bold, G Ferrari, S
Citation: S. Homann et al., Expression and purification of human recombinant GST-FGF receptor-1, J BIOTECH, 86(1), 2001, pp. 51-58
Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase
Authors: Hill, MM Andjelkovic, M Brazil, DP Ferrari, S Fabbro, D Hemmings, BA
Citation: Mm. Hill et al., Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase, J BIOL CHEM, 276(28), 2001, pp. 25643-25646
The phosphatidylinositide 3 '-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C
Authors: Tenzer, A Zingg, D Rocha, S Hemmings, B Fabbro, D Glanzmann, C Schubiger, PA Bodis, S Prusch, M
Citation: A. Tenzer et al., The phosphatidylinositide 3 '-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C, CANCER RES, 61(22), 2001, pp. 8203-8210
Differential p53-dependent mechanism of radiosensitization in vitro and invivo by the protein kinase C-specific inhibitor PKC412
Authors: Zaugg, K Rocha, S Resch, H Hegyi, I Oehler, C Glanzmann, C Fabbro, D Bodis, S Pruschy, M
Citation: K. Zaugg et al., Differential p53-dependent mechanism of radiosensitization in vitro and invivo by the protein kinase C-specific inhibitor PKC412, CANCER RES, 61(2), 2001, pp. 732-738
Protein kinase C inhibitor and irradiation-induced apoptosis: Relevance ofthe cytochrome c-mediated caspase-9 death pathway
Authors: Rocha, S Soengas, MS Lowe, SW Glanzmann, C Fabbro, D Winterhalter, K Bodis, S Pruschy, M
Citation: S. Rocha et al., Protein kinase C inhibitor and irradiation-induced apoptosis: Relevance ofthe cytochrome c-mediated caspase-9 death pathway, CELL GROWTH, 11(9), 2000, pp. 491-499
Factor V Leiden increases plasma F1+2 levels both in normal and deep venous thrombosis subjects
Authors: Mercuri, F Giacomello, R Puglisi, F Colaone, R Fabbro, D Menegon, MG Ceriello, A Gonano, F Damante, G
Citation: F. Mercuri et al., Factor V Leiden increases plasma F1+2 levels both in normal and deep venous thrombosis subjects, HAEMATOLOG, 85(4), 2000, pp. 386-389
Consequences of the inhibition of Hdm2 expression in human osteosarcoma cells using antisense oligonucleotides
Authors: Geiger, T Husken, D Weiler, J Natt, F Woods-Cook, KA Hall, J Fabbro, D
Citation: T. Geiger et al., Consequences of the inhibition of Hdm2 expression in human osteosarcoma cells using antisense oligonucleotides, ANTI-CAN DR, 15(6), 2000, pp. 423-430
PKC412 - a protein kinase inhibitor with a broad therapeutic potential
Authors: Fabbro, D Ruetz, S Bodis, S Pruschy, M Csermak, K Man, A Campochiaro, P Wood, J O'Reilly, T Meyer, T
Citation: D. Fabbro et al., PKC412 - a protein kinase inhibitor with a broad therapeutic potential, ANTI-CAN DR, 15(1), 2000, pp. 17-28
A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines
Authors: Chene, P Fuchs, J Bohn, J Garcia-Echeverria, C Furet, P Fabbro, D
Citation: P. Chene et al., A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines, J MOL BIOL, 299(1), 2000, pp. 245-253
bcl-xL antisense treatment induces apoptosis in breast carcinoma cells
Authors: Simoes-Wust, AP Olie, RA Gautschi, O Leech, SH Haner, R Hall, J Fabbro, D Stahel, RA Zangemeister-Wittke, U
Citation: Ap. Simoes-wust et al., bcl-xL antisense treatment induces apoptosis in breast carcinoma cells, INT J CANC, 87(4), 2000, pp. 582-590
Thyroid-specific gene expression is differentially influenced by intracellular glutathione level in FRTL-5 cells
Authors: Lonigro, R Donnini, D Fabbro, D Perrella, G Damante, G Impiombato, FSA Curcio, F
Citation: R. Lonigro et al., Thyroid-specific gene expression is differentially influenced by intracellular glutathione level in FRTL-5 cells, ENDOCRINOL, 141(3), 2000, pp. 901-909
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
Authors: Olie, RA Simoes-Wust, AP Baumann, B Leech, SH Fabbro, D Stahel, RA Zangemeister-Wittke, U
Citation: Ra. Olie et al., A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy, CANCER RES, 60(11), 2000, pp. 2805-2809
Protein kinase C in human renal cell carcinomas: role in invasion and differential isoenzyme expression
Authors: Engers, R Mrzyk, S Springer, E Fabbro, D Weissgerber, G Gerharz, CD Gabbert, HE
Citation: R. Engers et al., Protein kinase C in human renal cell carcinomas: role in invasion and differential isoenzyme expression, BR J CANC, 82(5), 2000, pp. 1063-1069
Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf
Authors: Fabbro, D Monia, BP Altmann, KH Geiger, T
Citation: D. Fabbro et al., Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf, METH MOL M, 35, 2000, pp. 167-188
Homogeneous purification of human recombinant GST-Akt/PKB from Sf9 cells
Authors: Fabbro, D Batt, D Rose, P Schacher, B Roberts, TM Ferrari, S
Citation: D. Fabbro et al., Homogeneous purification of human recombinant GST-Akt/PKB from Sf9 cells, PROT EX PUR, 17(1), 1999, pp. 83-88
Synthesis and antimicrobial activities of monoindolyl- and bisindolyloximes
Authors: Prudhomme, M Sancelme, M Bonnefoy, A Fabbro, D Meyer, T
Citation: M. Prudhomme et al., Synthesis and antimicrobial activities of monoindolyl- and bisindolyloximes, EUR J MED C, 34(2), 1999, pp. 161-165
Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent
Authors: Fabbro, D Buchdunger, E Wood, J Mestan, J Hofmann, F Ferrari, S Mett, H O'Reilly, T Meyer, T
Citation: D. Fabbro et al., Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent, PHARM THERA, 82(2-3), 1999, pp. 293-301
Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent
Authors: Moreau, P Anizon, F Sancelme, M Prudhomme, M Bailly, C Severe, D Riou, JF Fabbro, D Meyer, T Aubertin, AM
Citation: P. Moreau et al., Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent, J MED CHEM, 42(4), 1999, pp. 584-592
Synthesis, mode of action, and biological activities of rebeccamycin bromoderivatives
Authors: Moreau, P Anizon, F Sancelme, M Prudhomme, M Severe, D Riou, JF Goossens, JF Henichart, JP Bailly, C Labourier, E Tazzi, J Fabbro, D Meyer, T Aubertin, AM
Citation: P. Moreau et al., Synthesis, mode of action, and biological activities of rebeccamycin bromoderivatives, J MED CHEM, 42(10), 1999, pp. 1816-1822
Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility
Authors: Gay, B Suarez, S Weber, C Rahuel, J Fabbro, D Furet, P Caravatti, G Schoepfer, J
Citation: B. Gay et al., Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility, J BIOL CHEM, 274(33), 1999, pp. 23311-23315
A derivative of staurosporine (CGP 41 : 251) shows selectivity for PKC inhibition and in vitro antiproliferative effects as well as in vivo antitumoractivity. (vol 43, pg 851, 1989)
Authors: Meyer, T Regenass, U Fabbro, D Alteri, E Rosel, J Muller, M Caravatti, G Matter, A
Citation: T. Meyer et al., A derivative of staurosporine (CGP 41 : 251) shows selectivity for PKC inhibition and in vitro antiproliferative effects as well as in vivo antitumoractivity. (vol 43, pg 851, 1989), INT J CANC, 81(4), 1999, pp. 669-669
Second generation of antisense oligonucleotides: From nuclease resistance to biological efficacy in animals (vol 50, pg 168, 1996)
Authors: Altmann, KH Dean, NM Fabbro, D Freier, SM Geiger, T Haner, R Husken, D Martin, P Monia, BP Muller, M Natt, F Nicklin, P Phillips, J Pieles, U Sasmor, H Moser, HE
Citation: Kh. Altmann et al., Second generation of antisense oligonucleotides: From nuclease resistance to biological efficacy in animals (vol 50, pg 168, 1996), CHIMIA, 53(5), 1999, pp. 241-241
The protein kinase C inhibitor CGP41251 suppresses cytokine release and extracellular signal-regulated kinase 2 expression in cancer patients
Authors: Thavasu, P Propper, D McDonald, A Dobbs, N Ganesan, T Talbot, D Braybrook, J Caponigro, F Hutchison, C Twelves, C Man, A Fabbro, D Harris, A Balkwill, F
Citation: P. Thavasu et al., The protein kinase C inhibitor CGP41251 suppresses cytokine release and extracellular signal-regulated kinase 2 expression in cancer patients, CANCER RES, 59(16), 1999, pp. 3980-3984
PKC 412
Authors: Lansiaux, A Fabbro, D Meyer, T Hamy, F Bailly, C
Citation: A. Lansiaux et al., PKC 412, B CANCER, 86(7-8), 1999, pp. 614-617
Risultati: 1-25 | 26-27