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Results: 1-25 | 26-32
Results: 1-25/32
Structure of the N-terminal region of Haemophilus influenzae HI0017: Implications for function
Authors: Yu, LP Mack, J Hajduk, P Fesik, SW
Citation: Lp. Yu et al., Structure of the N-terminal region of Haemophilus influenzae HI0017: Implications for function, J BIOM NMR, 20(2), 2001, pp. 105-110
Structural basis for the inhibition of caspase-3 by XIAP
Authors: Riedl, SJ Renatus, M Schwarzenbacher, R Zhou, Q Sun, CH Fesik, SW Liddington, RC Salvesen, GS
Citation: Sj. Riedl et al., Structural basis for the inhibition of caspase-3 by XIAP, CELL, 104(5), 2001, pp. 791-800
Structural biology - Controlling the caspases
Authors: Fesik, SW Shi, YG
Citation: Sw. Fesik et Yg. Shi, Structural biology - Controlling the caspases, SCIENCE, 294(5546), 2001, pp. 1477-1478
Solution structure of the antiapoptotic protein bcl-2
Authors: Petros, AM Medek, A Nettesheim, DG Kim, DH Yoon, HS Swift, K Matayoshi, ED Oltersdorf, T Fesik, SW
Citation: Am. Petros et al., Solution structure of the antiapoptotic protein bcl-2, P NAS US, 98(6), 2001, pp. 3012-3017
Solution structure and function of a conserved protein SP14.3 encoded by an essential Streptococcus pneumoniae gene
Authors: Yu, LP Gunasekera, AH Mack, J Olejniczak, ET Chovan, LE Ruan, XA Towne, DL Lerner, CG Fesik, SW
Citation: Lp. Yu et al., Solution structure and function of a conserved protein SP14.3 encoded by an essential Streptococcus pneumoniae gene, J MOL BIOL, 311(3), 2001, pp. 593-604
Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties
Authors: Liu, G Huth, JR Olejniczak, ET Mendoza, R DeVries, P Leitza, S Reilly, EB Okasinski, GF Fesik, SW von Geldern, TW
Citation: G. Liu et al., Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties, J MED CHEM, 44(8), 2001, pp. 1202-1210
Rational design of diflunisal analogues with reduced affinity for human serum albumin
Authors: Mao, HY Hajduk, PJ Craig, R Bell, R Borre, T Fesik, SW
Citation: Hy. Mao et al., Rational design of diflunisal analogues with reduced affinity for human serum albumin, J AM CHEM S, 123(43), 2001, pp. 10429-10435
14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
Authors: Datta, SR Katsov, A Hu, L Petros, A Fesik, SW Yaffe, MB Greenberg, ME
Citation: Sr. Datta et al., 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation, MOL CELL, 6(1), 2000, pp. 41-51
Expression, refolding, and isotopic labeling of human serum albumin domains for NMR spectroscopy
Authors: Mao, HY Gunasekera, AH Fesik, SW
Citation: Hy. Mao et al., Expression, refolding, and isotopic labeling of human serum albumin domains for NMR spectroscopy, PROT EX PUR, 20(3), 2000, pp. 492-499
Rationale for Bcl-x(L)/Bad peptide complex formation from structure, mutagenesis, and biophysical studies
Authors: Petros, AM Nettesheim, DG Wang, Y Olejniczak, ET Meadows, RP Mack, J Swift, K Matayoshi, ED Zhang, HC Thompson, CB Fesik, SW
Citation: Am. Petros et al., Rationale for Bcl-x(L)/Bad peptide complex formation from structure, mutagenesis, and biophysical studies, PROTEIN SCI, 9(12), 2000, pp. 2528-2534
An approach for high-throughput structure determination of proteins by NMRspectroscopy
Authors: Medek, A Olejniczak, ET Meadows, RP Fesik, SW
Citation: A. Medek et al., An approach for high-throughput structure determination of proteins by NMRspectroscopy, J BIOM NMR, 18(3), 2000, pp. 229-238
Insights into programmed cell death through structural biology
Authors: Fesik, SW
Citation: Sw. Fesik, Insights into programmed cell death through structural biology, CELL, 103(2), 2000, pp. 273-282
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
Authors: Liu, ZH Sun, CH Olejniczak, ET Meadows, RP Betz, SF Oost, T Herrmann, J Wu, JC Fesik, SW
Citation: Zh. Liu et al., Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain, NATURE, 408(6815), 2000, pp. 1004-1008
NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding
Authors: Huth, JR Olejniczak, ET Mendoza, R Liang, H Harris, EAS Lupher, ML Wilson, AE Fesik, SW Staunton, DE
Citation: Jr. Huth et al., NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding, P NAS US, 97(10), 2000, pp. 5231-5236
Design of adenosine kinase inhibitors from the NMR-based screening of fragments
Authors: Hajduk, PJ Gomtsyan, A Didomenico, S Cowart, M Bayburt, EK Solomon, L Severin, J Smith, R Walter, K Holzman, TF Stewart, A McGaraughty, S Jarvis, MF Kowaluk, EA Fesik, SW
Citation: Pj. Hajduk et al., Design of adenosine kinase inhibitors from the NMR-based screening of fragments, J MED CHEM, 43(25), 2000, pp. 4781-4786
Identification of novel inhibitors of urokinase via NMR-based screening
Authors: Hajduk, PJ Boyd, S Nettesheim, D Nienaber, V Severin, J Smith, R Davidson, D Rockway, T Fesik, SW
Citation: Pj. Hajduk et al., Identification of novel inhibitors of urokinase via NMR-based screening, J MED CHEM, 43(21), 2000, pp. 3862-3866
Privileged molecules for protein binding identified from NMR-based screening
Authors: Hajduk, PJ Bures, M Praestgaard, J Fesik, SW
Citation: Pj. Hajduk et al., Privileged molecules for protein binding identified from NMR-based screening, J MED CHEM, 43(18), 2000, pp. 3443-3447
NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP
Authors: Sun, CH Cai, ML Meadows, RP Xu, N Gunasekera, AH Herrmann, J Wu, JC Fesik, SW
Citation: Ch. Sun et al., NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP, J BIOL CHEM, 275(43), 2000, pp. 33777-33781
NMR studies of the anti-apoptotic protein Bcl-x(L) in micelles
Authors: Losonczi, JA Olejniczak, ET Betz, SF Harlan, JE Mack, J Fesik, SW
Citation: Ja. Losonczi et al., NMR studies of the anti-apoptotic protein Bcl-x(L) in micelles, BIOCHEM, 39(36), 2000, pp. 11024-11033
The use of differential chemical shifts for determining the binding site location and orientation of protein-bound ligands
Authors: Medek, A Hajduk, PJ Mack, J Fesik, SW
Citation: A. Medek et al., The use of differential chemical shifts for determining the binding site location and orientation of protein-bound ligands, J AM CHEM S, 122(6), 2000, pp. 1241-1242
NMR-based screening of proteins containing C-13-labeled methyl groups
Authors: Hajduk, PJ Augeri, DJ Mack, J Mendoza, R Yang, JG Betz, SF Fesik, SW
Citation: Pj. Hajduk et al., NMR-based screening of proteins containing C-13-labeled methyl groups, J AM CHEM S, 122(33), 2000, pp. 7898-7904
Accurate measurement of H-N-H-alpha residual dipolar couplings in proteins
Authors: Cai, ML Wang, H Olejniczak, ET Meadows, RP Gunasekera, AH Xu, N Fesik, SW
Citation: Ml. Cai et al., Accurate measurement of H-N-H-alpha residual dipolar couplings in proteins, J MAGN RES, 139(2), 1999, pp. 451-453
NMR-based discovery of phosphotyrosine mimetics that bind to the Lck SH2 domain
Authors: Hajduk, PJ Zhou, MM Fesik, SW
Citation: Pj. Hajduk et al., NMR-based discovery of phosphotyrosine mimetics that bind to the Lck SH2 domain, BIOORG MED, 9(16), 1999, pp. 2403-2406
The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptoticfunction of Bcl-x(L)
Authors: Chang, BS Kelekar, A Harris, MH Harlan, JE Fesik, SW Thompson, CB
Citation: Bs. Chang et al., The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptoticfunction of Bcl-x(L), MOL CELL B, 19(10), 1999, pp. 6673-6681
Bcl-x(L) regulates apoptosis by heterodimerization-dependent and -independent mechanisms
Authors: Minn, AJ Kettlun, CS Liang, H Kelekar, A Vander Heiden, MG Chang, BS Fesik, SW Fill, M Thompson, CB
Citation: Aj. Minn et al., Bcl-x(L) regulates apoptosis by heterodimerization-dependent and -independent mechanisms, EMBO J, 18(3), 1999, pp. 632-643
Risultati: 1-25 | 26-32