Authors:
Hamid, M
McCluskey, JT
McClenaghan, NH
Flatt, PR
Citation: M. Hamid et al., Comparative functional study of clonal insulin-secreting cells cultured infive commercially available tissue culture media, CELL TRANSP, 10(2), 2001, pp. 153-159
Citation: Fpm. O'Harte et al., Degradation and glycemic effects of His(7)-glucitol glucagon-like peptide-1(7-36)amide in obese diabetic ob/ob mice, REGUL PEPT, 96(3), 2001, pp. 95-104
Citation: Nh. Mcclenaghan et al., Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure, BIOCH PHARM, 61(5), 2001, pp. 527-536
Authors:
McKillop, AM
Mooney, MH
Harriott, P
Flatt, PR
O'Harte, FPM
Citation: Am. Mckillop et al., Evaluation of glycated insulin in diabetic animals using immunocytochemistry and radioimmunoassay, BIOC BIOP R, 286(3), 2001, pp. 524-528
Authors:
Salgado, AP
Santos, RM
Fernandes, AP
Tome, AR
Flatt, PR
Rosario, LM
Citation: Ap. Salgado et al., Glucose-mediated Ca2+ signalling in single clonal insulin-secreting cells:evidence for a mixed model of cellular activation, INT J BIO C, 32(5), 2000, pp. 557-569
Citation: Aj. Ball et al., Stimulation of insulin secretion in clonal BRIN-BD11 cells by the imidazoline derivatives KU14R and RX801080, PHARMAC RES, 42(6), 2000, pp. 575-579
Citation: M. Ahmad et al., The role of the cyclic GMP-inhibited cyclic AMP-specific phosphodiesterase(PDE3) in regulating clonal BRIN-BD11 insulin secreting cell survival, CELL SIGNAL, 12(8), 2000, pp. 541-548
Citation: Nh. Mcclenaghan et Pr. Flatt, Metabolic and K-ATP channel-independent actions of keto acid initiators ofinsulin secretion, PANCREAS, 20(1), 2000, pp. 38-46
Authors:
Boyd, AC
Abdel-Wahab, YHA
McKillop, AM
McNulty, H
Barnett, CR
O'Harte, FPM
Flatt, PR
Citation: Ac. Boyd et al., Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle, BBA-GEN SUB, 1523(1), 2000, pp. 128-134
Authors:
O'Harte, FPM
Mooney, MH
Lawlor, A
Flatt, PR
Citation: Fpm. O'Harte et al., N-terminally modified glucagon-like peptide-1(7-36) amide exhibits resistance to enzymatic degradation while maintaining its antihyperglycaemic activity in vivo, BBA-GEN SUB, 1474(1), 2000, pp. 13-22
Authors:
O'Harte, FPM
Boyd, AC
McKillop, AM
Abdel-Wahab, YHA
McNulty, H
Barnett, CR
Conlon, JM
Hojrup, P
Flatt, PR
Citation: Fpm. O'Harte et al., Structure, antihyperglycemic activity and cellular actions of a novel diglycated human insulin, PEPTIDES, 21(10), 2000, pp. 1519-1526
Authors:
Hamid, M
McCluskey, JT
McClenaghan, NH
Flatt, PR
Citation: M. Hamid et al., Culture and function of electrofusion-derived clonal insulin-secreting cells immobilized on solid and macroporous microcarrier beads, BIOSCI REP, 20(3), 2000, pp. 167-176
Citation: Am. Gray et al., The traditional plant treatment, Sambucus nigra (elder), exhibits insulin-like and insulin-releasing actions in vitro, J NUTR, 130(1), 2000, pp. 15-20
Authors:
McKillop, AM
McCluskey, JT
Boyd, AC
Mooney, MH
Flatt, PR
O'Harte, FPM
Citation: Am. Mckillop et al., Production and characterization of specific antibodies for evaluation of glycated insulin in plasma and biological tissues, J ENDOCR, 167(1), 2000, pp. 153-163
Citation: Fpm. O'Harte et al., Improved glycaemic control in obese diabetic ob/ob mice using N-terminallymodified gastric inhibitory polypeptide, J ENDOCR, 165(3), 2000, pp. 639-648
Authors:
Conroy, SJ
Abdel-Wahab, YHA
Caraher, EM
Byrne, PM
Murphy, E
Nolan, J
Flatt, PR
Newsholme, P
Citation: Sj. Conroy et al., Evidence for complement-dependent and -independent inhibition of insulin secretion from clonal beta-cells incubated in the presence of sera of newly diagnosed IDDM patients, J ENDOCR, 164(2), 2000, pp. 139-147
Citation: Aj. Ball et al., Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide, EUR J PHARM, 408(3), 2000, pp. 327-333
Citation: Nh. Mcclenaghan et al., Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide, BR J PHARM, 130(2), 2000, pp. 478-484
Authors:
Ahmad, M
Abdel-Wahab, YHA
Tate, R
Flatt, PR
Pyne, NJ
Furman, BL
Citation: M. Ahmad et al., Effect of type-selective inhibitors on cyclic nucleotide phosphodiesteraseactivity and insulin secretion in the clonal insulin secreting cell Line BRIN-BD11, BR J PHARM, 129(6), 2000, pp. 1228-1234
Citation: Nh. Mcclenaghan et Pr. Flatt, Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines, DIABET OB M, 1(3), 1999, pp. 137-150
Citation: Nh. Mcclenaghan et Pr. Flatt, Glucose and non-glucidic nutrients exert permissive effects on 2-keto acidregulation of pancreatic beta-cell function, BBA-GEN SUB, 1426(1), 1999, pp. 110-118
Authors:
Salgado, AP
Pereira, FC
Seica, RM
Fernandes, AP
Flatt, PR
Santos, RM
Rosario, LM
Ramasamy, R
Citation: Ap. Salgado et al., Modulation of glucose-induced insulin secretion by cytosolic redox state in clonal beta-cells, MOL C ENDOC, 154(1-2), 1999, pp. 79-88
Citation: Yha. Abdel-wahab et al., N-terminal glycation of cholecystokinin-8 abolishes its insulinotropic action on clonal pancreatic B-cells, BBA-MOL CEL, 1452(1), 1999, pp. 60-67