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Results: 1-25 | 26-31
Results: 1-25/31
Kinetics of testosterone 6 beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome P450 oxidoreductase and cytochrome B-5 to human liver microsomes
Authors: Taguchi, M Imaoka, S Yoshii, K Kobayashi, K Hosokawa, M Shimada, N Funae, Y Chiba, K
Citation: M. Taguchi et al., Kinetics of testosterone 6 beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome P450 oxidoreductase and cytochrome B-5 to human liver microsomes, RES COM M P, 109(1-2), 2001, pp. 53-63
Functional evaluation of cytochrome P450 2D6 with Gly(42)Arg substitution expressed in Saccharomyces cerevisiae
Authors: Tsuzuki, D Takemi, C Yamamoto, S Tamagake, K Imaoka, S Funae, Y Kataoka, H Shinoda, S Narimatsu, S
Citation: D. Tsuzuki et al., Functional evaluation of cytochrome P450 2D6 with Gly(42)Arg substitution expressed in Saccharomyces cerevisiae, PHARMACOGEN, 11(8), 2001, pp. 709-718
Escape from tolerance of organic nitrate by induction of cytochrome P450
Authors: Minamiyama, Y Imaoka, S Takemura, S Okada, S Inoue, M Funae, Y
Citation: Y. Minamiyama et al., Escape from tolerance of organic nitrate by induction of cytochrome P450, FREE RAD B, 31(11), 2001, pp. 1498-1508
Involvement of human liver cytochrome P4502B6 in the metabolism of propofol
Authors: Oda, Y Hamaoka, N Hiroi, T Imaoka, S Hase, I Tanaka, K Funae, Y Ishizaki, T Asada, A
Citation: Y. Oda et al., Involvement of human liver cytochrome P4502B6 in the metabolism of propofol, BR J CL PH, 51(3), 2001, pp. 281-285
Androgen regulation of CYP4B1 responsible for mutagenic activation of bladder carcinogens in the rat bladder: detection of CYP4B1 mRNA by competitivereverse transcription-polymerase chain reaction
Authors: Imaoka, S Yoneda, Y Sugimoto, T Ikemoto, S Hiroi, T Yamamoto, K Nakatani, T Funae, Y
Citation: S. Imaoka et al., Androgen regulation of CYP4B1 responsible for mutagenic activation of bladder carcinogens in the rat bladder: detection of CYP4B1 mRNA by competitivereverse transcription-polymerase chain reaction, CANCER LETT, 166(2), 2001, pp. 119-123
Presence of a no-observed effect level for enhancing effects of development of the alpha-isomer of benzene hexachloride (alpha-BHC) on diethylnitrosamine-initiated hepatic foci in rats
Authors: Masuda, C Wanibuchi, H Otori, K Wei, M Yamamoto, S Hiroi, T Imaoka, S Funae, Y Fukushima, S
Citation: C. Masuda et al., Presence of a no-observed effect level for enhancing effects of development of the alpha-isomer of benzene hexachloride (alpha-BHC) on diethylnitrosamine-initiated hepatic foci in rats, CANCER LETT, 163(2), 2001, pp. 179-185
Study of cytochrome P4502E1 mRNA level of mononuclear cells in patients with alcoholic liver disease
Authors: Yano, H Tsutsumi, M Fukura, M Chen, WB Shimanaka, K Tsuchishima, M Takase, S Imaoka, S Funae, Y
Citation: H. Yano et al., Study of cytochrome P4502E1 mRNA level of mononuclear cells in patients with alcoholic liver disease, ALC CLIN EX, 25(6), 2001, pp. 2S-6S
A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine
Authors: Hashizume, T Mise, M Matsumoto, S Terauchi, Y Fujii, T Imaoka, S Funae, Y Kamataki, T Miyazaki, H
Citation: T. Hashizume et al., A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine, DRUG META D, 29(6), 2001, pp. 798-805
Progesterone oxidation by cytochrome P450 2D isoforms in the brain
Authors: Hiroi, T Kishimoto, W Chow, T Imaoka, S Igarashi, TS Funae, Y
Citation: T. Hiroi et al., Progesterone oxidation by cytochrome P450 2D isoforms in the brain, ENDOCRINOL, 142(9), 2001, pp. 3901-3908
A transgenic mouse expressing human CYP4B1 in the liver
Authors: Imaoka, S Hayashi, K Hiroi, T Yabusaki, Y Kamataki, T Funae, Y
Citation: S. Imaoka et al., A transgenic mouse expressing human CYP4B1 in the liver, BIOC BIOP R, 284(3), 2001, pp. 757-762
cDNA cloning and expression of a novel cytochrome P450 (CYP4F12) from human small intestine
Authors: Hashizume, T Imaoka, S Hiroi, T Terauchi, Y Fujii, T Miyazaki, H Kamataki, T Funae, Y
Citation: T. Hashizume et al., cDNA cloning and expression of a novel cytochrome P450 (CYP4F12) from human small intestine, BIOC BIOP R, 280(4), 2001, pp. 1135-1141
High index optical materials prepared by copolymerization of novel bifunctional thiomethacrylates
Authors: Matsuda, T Funae, Y Yoshida, M Yamamoto, T
Citation: T. Matsuda et al., High index optical materials prepared by copolymerization of novel bifunctional thiomethacrylates, J MACR S PU, 37(3), 2000, pp. 239-257
Quantitative RT-PCR for CYP3A4 mRNA in human peripheral lymphocytes: induction of CYP3A4 in lymphocytes and in liver by rifampicin
Authors: Nakamoto, T Hase, I Imaoka, S Hiroi, T Oda, Y Asada, A Funae, Y
Citation: T. Nakamoto et al., Quantitative RT-PCR for CYP3A4 mRNA in human peripheral lymphocytes: induction of CYP3A4 in lymphocytes and in liver by rifampicin, PHARMACOGEN, 10(6), 2000, pp. 571-575
Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments
Authors: Komatsu, K Ito, K Nakajima, Y Kanamitsu, S Imaoka, S Funae, Y Green, CE Tyson, CA Shimada, N Sugiyama, Y
Citation: K. Komatsu et al., Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments, DRUG META D, 28(4), 2000, pp. 475-481
Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes
Authors: Ishiguro, N Senda, C Kishimoto, W Sakai, K Funae, Y Igarashi, T
Citation: N. Ishiguro et al., Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes, XENOBIOTICA, 30(1), 2000, pp. 71-80
Novel bifunctional thiolcarboxylic acid esters useful as crosslinking agents for optical materials
Authors: Matsuda, T Funae, Y Yoshida, M Yamamoto, T
Citation: T. Matsuda et al., Novel bifunctional thiolcarboxylic acid esters useful as crosslinking agents for optical materials, SYN COMMUN, 30(16), 2000, pp. 3041-3045
Optical material of high refractive index resin composed of sulfur-containing aliphatic and alicyclic methacrylates
Authors: Matsuda, T Funae, Y Yoshida, M Yamamoto, T Takaya, T
Citation: T. Matsuda et al., Optical material of high refractive index resin composed of sulfur-containing aliphatic and alicyclic methacrylates, J APPL POLY, 76(1), 2000, pp. 45-49
Optical material of high refractive index resin composed of sulfur-containing aromatic methacrylates
Authors: Matsuda, T Funae, Y Yoshida, M Yamamoto, T Takaya, T
Citation: T. Matsuda et al., Optical material of high refractive index resin composed of sulfur-containing aromatic methacrylates, J APPL POLY, 76(1), 2000, pp. 50-54
CYP4B1 is a possible risk factor for bladder cancer in humans
Authors: Imaoka, S Yoneda, Y Sugimoto, T Hiroi, T Yamamoto, K Nakatani, T Funae, Y
Citation: S. Imaoka et al., CYP4B1 is a possible risk factor for bladder cancer in humans, BIOC BIOP R, 277(3), 2000, pp. 776-780
The decreased in vivo clearance of CYP2D6 substrates by CYP2D610 might becaused not only by the low-expression but also by low affinity of CYP2D6
Authors: Fukuda, T Nishida, Y Imaoka, S Hiroi, T Naohara, M Funae, Y Azuma, J
Citation: T. Fukuda et al., The decreased in vivo clearance of CYP2D6 substrates by CYP2D610 might becaused not only by the low-expression but also by low affinity of CYP2D6, ARCH BIOCH, 380(2), 2000, pp. 303-308
Area under the plasma concentration-time curve of inorganic fluoride following sevoflurane anesthesia correlates with CYP2E1 mRNA level in mononuclear cells
Authors: Hase, I Imaoka, S Oda, Y Hiroi, T Nakamoto, T Asada, A Funae, Y
Citation: I. Hase et al., Area under the plasma concentration-time curve of inorganic fluoride following sevoflurane anesthesia correlates with CYP2E1 mRNA level in mononuclear cells, ANESTHESIOL, 92(6), 2000, pp. 1661-1666
Novel thiophene methacrylates for materials of high refractive index
Authors: Matsuda, T Funae, Y Yoshida, M Takaya, T
Citation: T. Matsuda et al., Novel thiophene methacrylates for materials of high refractive index, J MACR S PU, 36(9), 1999, pp. 1271-1288
Inhibition of liver glutathione S-transferase placental form-positive focidevelopment in the rat hepatocarcinogenesis by Porphyra tenera (Asakusa-nori)
Authors: Ichihara, T Wanibuchi, H Taniyama, T Okai, Y Yano, Y Otani, S Imaoka, S Funae, Y Fukushima, S
Citation: T. Ichihara et al., Inhibition of liver glutathione S-transferase placental form-positive focidevelopment in the rat hepatocarcinogenesis by Porphyra tenera (Asakusa-nori), CANCER LETT, 141(1-2), 1999, pp. 211-218
Non-carcinogenicity, but dose-related increase in preneoplastic hepatocellular lesions, in a two-year feeding study of phenobarbital sodium in male F344 rats
Authors: Hagiwara, A Miyata, E Tamano, S Sano, M Masuda, C Funae, Y Ito, N Fukushima, S Shirai, T
Citation: A. Hagiwara et al., Non-carcinogenicity, but dose-related increase in preneoplastic hepatocellular lesions, in a two-year feeding study of phenobarbital sodium in male F344 rats, FOOD CHEM T, 37(8), 1999, pp. 869-879
Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia
Authors: Takemura, S Minamiyama, Y Imaoka, S Funae, Y Hirohashi, K Inoue, M Kinoshita, H
Citation: S. Takemura et al., Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia, J HEPATOL, 30(6), 1999, pp. 1035-1044
Risultati: 1-25 | 26-31