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Results: 1-25 | 26-44
Results: 1-25/44
SELECTION OF A COMBINATORIAL TETRAPEPTIDE LIBRARY ON FARNESYL-PROTEINTRANSFERASE YIELDS INHIBITORS COMPETITIVE WITH FARNESYL DIPHOSPHATE
Authors: PESSI A KOBLAN KS OLIFF A CORTESE R GIBBS JB WALLACE A
Citation: A. Pessi et al., SELECTION OF A COMBINATORIAL TETRAPEPTIDE LIBRARY ON FARNESYL-PROTEINTRANSFERASE YIELDS INHIBITORS COMPETITIVE WITH FARNESYL DIPHOSPHATE, Annals of oncology, 9, 1998, pp. 6-6
A FARNESYLTRANSFERASE INHIBITOR INDUCES TUMOR-REGRESSION IN TRANSGENIC MICE HARBORING MULTIPLE ONCOGENIC MUTATIONS BY MEDIATING ALTERATIONSIN BOTH CELL-CYCLE CONTROL AND APOPTOSIS
Authors: BARRINGTON RE SUBLER MA RANDS E OMER CA MILLER PJ HUNDLEY JE KOESTER SK TROYER DA BEARSS DJ CONNER MW GIBBS JB HAMILTON K KOBLAN KS MOSSER SD ONEILL TJ SCHABER MD SENDERAK ET WINDLE JJ OLIFF A KOHL NE
Citation: Re. Barrington et al., A FARNESYLTRANSFERASE INHIBITOR INDUCES TUMOR-REGRESSION IN TRANSGENIC MICE HARBORING MULTIPLE ONCOGENIC MUTATIONS BY MEDIATING ALTERATIONSIN BOTH CELL-CYCLE CONTROL AND APOPTOSIS, Molecular and cellular biology, 18(1), 1998, pp. 85-92
CLAVARIC ACID AND STEROIDAL ANALOGS AS RAS-DIRECTED AND FPP-DIRECTED INHIBITORS OF HUMAN FARNESYL-PROTEIN TRANSFERASE
Authors: LINGHAM RB SILVERMAN KC JAYASURIYA H KIM BM AMO SE WILSON FR REW DJ SCHABER MD BERGSTROM JD KOBLAN KS GRAHAM SL KOHL NE GIBBS JB SINGH SB
Citation: Rb. Lingham et al., CLAVARIC ACID AND STEROIDAL ANALOGS AS RAS-DIRECTED AND FPP-DIRECTED INHIBITORS OF HUMAN FARNESYL-PROTEIN TRANSFERASE, Journal of medicinal chemistry, 41(23), 1998, pp. 4492-4501
N-ARYLALKYL PSEUDOPEPTIDE INHIBITORS OF FARNESYLTRANSFERASE
Authors: DESOLMS SJ GIULIANI EA GRAHAM SL KOBLAN KS KOHL NE MOSSER SD OLIFF AI POMPLIANO DL RANDS E SCHOLZ TH WISCOUNT CM GIBBS JB SMITH RL
Citation: Sj. Desolms et al., N-ARYLALKYL PSEUDOPEPTIDE INHIBITORS OF FARNESYLTRANSFERASE, Journal of medicinal chemistry, 41(14), 1998, pp. 2651-2656
ANTITUMOR EFFECT OF A FARNESYL-PROTEIN TRANSFERASE INHIBITOR IN MAMMARY AND LYMPHOID TUMORS OVEREXPRESSING N-RAS IN TRANSGENIC MICE
Authors: MANGUES R CORRAL T KOHL NE SYMMANS WF LU SY MALUMBRES M GIBBS JB OLIFF A PELLICER A
Citation: R. Mangues et al., ANTITUMOR EFFECT OF A FARNESYL-PROTEIN TRANSFERASE INHIBITOR IN MAMMARY AND LYMPHOID TUMORS OVEREXPRESSING N-RAS IN TRANSGENIC MICE, Cancer research, 58(6), 1998, pp. 1253-1259
FARNESYLTRANSFERASE INHIBITORS VERSUS RAS INHIBITORS
Authors: GIBBS JB GRAHAM SL HARTMAN GD KOBLAN KS KOHL NE OMER CA OLIFF A
Citation: Jb. Gibbs et al., FARNESYLTRANSFERASE INHIBITORS VERSUS RAS INHIBITORS, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(2), 1997, pp. 197-203
DIARYLETHER INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Authors: DINSMORE CJ WILLIAMS TM HAMILTON K ONEILL TJ RANDS E KOBLAN KS KOHL NE GIBBS JB GRAHAM SL HARTMAN GD OLIFF AI
Citation: Cj. Dinsmore et al., DIARYLETHER INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE, Bioorganic & medicinal chemistry letters, 7(10), 1997, pp. 1345-1348
ANTITUMOR ACTIVITIES OF FARNESYLTRANSFERASE INHIBITORS
Authors: KOHL NE ANTHONY NJ CONNER MW DESOLMS SJ GIBBS JB GRAHAM L HARTMAN GD KOBLAN KS OMER CA PELLICER A WILLIAMS TM WINDLE JJ OLIFF A
Citation: Ne. Kohl et al., ANTITUMOR ACTIVITIES OF FARNESYLTRANSFERASE INHIBITORS, The FASEB journal, 11(9), 1997, pp. 797-797
THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS
Authors: GIBBS JB OLIFF A
Citation: Jb. Gibbs et A. Oliff, THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS, Annual review of pharmacology and toxicology, 37, 1997, pp. 143-166
KINASE-DEFICIENT PAK1 MUTANTS INHIBIT RAS TRANSFORMATION OF RAT-1 FIBROBLASTS
Authors: TANG Y CHEN ZX AMBROSE D LIU JH GIBBS JB CHERNOFF J FIELD J
Citation: Y. Tang et al., KINASE-DEFICIENT PAK1 MUTANTS INHIBIT RAS TRANSFORMATION OF RAT-1 FIBROBLASTS, Molecular and cellular biology, 17(8), 1997, pp. 4454-4464
FARNESYLTRANSFERASE INHIBITORS - A NEW CLASS OF CANCER CHEMOTHERAPEUTICS
Authors: KOBLAN KS KOHL NE OMER CA ANTHONY NJ CONNER MW DESOLMS SJ WILLIAMS TM GRAHAM SL HARTMAN GD OLIFF A GIBBS JB
Citation: Ks. Koblan et al., FARNESYLTRANSFERASE INHIBITORS - A NEW CLASS OF CANCER CHEMOTHERAPEUTICS, Biochemical Society transactions, 24(3), 1996, pp. 688-692
FARNESYLTRANSFERASE INHIBITORS AND ANTI-RAS THERAPY
Authors: GIBBS JB KOHL NE KOBLAN KS OMER CA SEPPLORENZINO L ROSEN N ANTHONY NJ CONNER MW DESOLMS SJ WILLIAMS TM GRAHAM SL HARTMAN GD OLIFF A
Citation: Jb. Gibbs et al., FARNESYLTRANSFERASE INHIBITORS AND ANTI-RAS THERAPY, Breast cancer research and treatment, 38(1), 1996, pp. 75-83
NEW MOLECULAR TARGETS FOR CANCER-THERAPY
Authors: OLIFF A GIBBS JB MCCORMICK F
Citation: A. Oliff et al., NEW MOLECULAR TARGETS FOR CANCER-THERAPY, Scientific American, 275(3), 1996, pp. 144-149
CHEMISTRY AND BIOLOGY OF CYLINDROLS - NOVEL INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE FROM CYLINDROCARPON LUCIDUM
Authors: SINGH SB BALL RG BILLS GF CASCALES C GIBBS JB GOETZ MA HOOGSTEEN K JENKINS RG LIESCH JM LINGHAM RB SILVERMAN KC ZINK DL
Citation: Sb. Singh et al., CHEMISTRY AND BIOLOGY OF CYLINDROLS - NOVEL INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE FROM CYLINDROCARPON LUCIDUM, Journal of organic chemistry, 61(22), 1996, pp. 7727-7737
A-SUBSTITUTED PIPERAZINES AS CONSTRAINED AMINO-ACIDS - APPLICATION TOTHE SYNTHESIS OF POTENT, NON CARBOXYLIC-ACID INHIBITORS OF FARNESYLTRANSFERASE
Authors: WILLIAMS TM CICCARONE TM MACTOUGH SC BOCK RL CONNER MW DAVIDE JP HAMILTON K KOBLAN KS KOHL NE KRAL AM MOSSER SD OMER CA POMPLIANO DL RANDS E SCHABER MD SHAH D WILSON FR GIBBS JB GRAHAM SL HARTMAN GD OLIFF AI SMITH RL
Citation: Tm. Williams et al., A-SUBSTITUTED PIPERAZINES AS CONSTRAINED AMINO-ACIDS - APPLICATION TOTHE SYNTHESIS OF POTENT, NON CARBOXYLIC-ACID INHIBITORS OF FARNESYLTRANSFERASE, Journal of medicinal chemistry, 39(7), 1996, pp. 1345-1348
SELECTION OF POTENT INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE FROM ASYNTHETIC TETRAPEPTIDE COMBINATORIAL LIBRARY
Authors: WALLACE A KOBLAN KS HAMILTON K MARQUISOMER DJ MILLER PJ MOSSER SD OMER CA SCHABER MD CORTESE R OLIFF A GIBBS JB PESSI A
Citation: A. Wallace et al., SELECTION OF POTENT INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE FROM ASYNTHETIC TETRAPEPTIDE COMBINATORIAL LIBRARY, The Journal of biological chemistry, 271(49), 1996, pp. 31306-31311
INHIBITION OF FARNESYLTRANSFERASE INDUCES REGRESSION OF MAMMARY AND SALIVARY CARCINOMAS IN RAS TRANSGENIC MICE
Authors: KOHL NE OMER CA CONNER MW ANTHONY NJ DAVIDE JP DESOLMS SJ GIULIANI EA GOMEZ RP GRAHAM SL HAMILTON K HANDT LK HARTMAN GD KOBLAN KS KRAL AM MILLER PJ MOSSER SD ONEILL TJ RANDS E SCHABER MD GIBBS JB OLIFF A
Citation: Ne. Kohl et al., INHIBITION OF FARNESYLTRANSFERASE INDUCES REGRESSION OF MAMMARY AND SALIVARY CARCINOMAS IN RAS TRANSGENIC MICE, Nature medicine, 1(8), 1995, pp. 792-797
DEVELOPMENT OF INHIBITORS OF PROTEIN FARNESYLATION AS POTENTIAL CHEMOTHERAPEUTIC-AGENTS
Authors: KOHL NE CONNER MW GIBBS JB GRAHAM SL HARTMAN GD OLIFF A
Citation: Ne. Kohl et al., DEVELOPMENT OF INHIBITORS OF PROTEIN FARNESYLATION AS POTENTIAL CHEMOTHERAPEUTIC-AGENTS, Journal of cellular biochemistry, 1995, pp. 145-150
SRC-HOMOLOGY-2 (SH2) DOMAIN LIGATION AS AN ALLOSTERIC REGULATOR - MODULATION OF PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE-C-GAMMA-1 STRUCTUREAND ACTIVITY
Authors: KOBLAN KS SCHABER MD EDWARDS G GIBBS JB POMPLIANO DL
Citation: Ks. Koblan et al., SRC-HOMOLOGY-2 (SH2) DOMAIN LIGATION AS AN ALLOSTERIC REGULATOR - MODULATION OF PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE-C-GAMMA-1 STRUCTUREAND ACTIVITY, Biochemical journal, 305, 1995, pp. 745-751
ACTINOPLANIC-ACID-A AND ACTINOPLANIC-ACID-B AS NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Authors: SILVERMAN KC CASCALES C GENILLOUD O SIGMUND JM GARTNER SE KOCH GE GAGLIARDI MM HEIMBUCH BK NALLINOMSTEAD M SANCHEZ M DIEZ MT MARTIN I GARRITY GM HIRSCH CF GIBBS JB SINGH SB LINGHAM RB
Citation: Kc. Silverman et al., ACTINOPLANIC-ACID-A AND ACTINOPLANIC-ACID-B AS NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE, Applied microbiology and biotechnology, 43(4), 1995, pp. 610-616
PSEUDODIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE
Authors: DESOLMS SJ DEANA AA GIULIANI EA GRAHAM SL KOHL NE MOSSER SD OLIFF AI POMPLIANO DL RANDS E SCHOLZ TH WIGGINS JM GIBBS JB SMITH RL
Citation: Sj. Desolms et al., PSEUDODIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE, Journal of medicinal chemistry, 38(20), 1995, pp. 3967-3971
PEPTIDOMIMETIC INHIBITOR OF FARNESYL, PROTEIN TRANSFERASE BLOCKS THE ANCHORAGE-DEPENDENT AND ANCHORAGE-INDEPENDENT GROWTH OF HUMAN TUMOR-CELL LINES
Authors: SEPPLORENZINO L MA ZP BANDS E KOHL NE GIBBS JB OLIFF A ROSEN N
Citation: L. Sepplorenzino et al., PEPTIDOMIMETIC INHIBITOR OF FARNESYL, PROTEIN TRANSFERASE BLOCKS THE ANCHORAGE-DEPENDENT AND ANCHORAGE-INDEPENDENT GROWTH OF HUMAN TUMOR-CELL LINES, Cancer research, 55(22), 1995, pp. 5302-5309
NEW FUNGAL METABOLITES AS POTENTIAL ANTIHYPERCHOLESTEROLEMICS AND ANTICANCER AGENTS
Authors: HUANG LY LINGHAM RB HARRIS GH SINGH SB DUFRESNE C NALLINOMSTEAD M BILLS GF MOJENA M SANCHEZ M KARKAS JD GIBBS JB CLAPP WH MEINZ MS SILVERMAN KC BERGSTROM JD
Citation: Ly. Huang et al., NEW FUNGAL METABOLITES AS POTENTIAL ANTIHYPERCHOLESTEROLEMICS AND ANTICANCER AGENTS, Canadian journal of botany, 73, 1995, pp. 898-906
PROTEIN PRENYLATION IN EUKARYOTIC MICROORGANISMS - GENETICS, BIOLOGY AND BIOCHEMISTRY
Authors: OMER CA GIBBS JB
Citation: Ca. Omer et Jb. Gibbs, PROTEIN PRENYLATION IN EUKARYOTIC MICROORGANISMS - GENETICS, BIOLOGY AND BIOCHEMISTRY, Molecular microbiology, 11(2), 1994, pp. 219-225
SELECTIVE-INHIBITION OF RAS-DEPENDENT CELL-TRANSFORMATION BY INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Authors: OLIFF A KOHL NE GRAHAM SL HARTMAN GD GIBBS JB
Citation: A. Oliff et al., SELECTIVE-INHIBITION OF RAS-DEPENDENT CELL-TRANSFORMATION BY INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE, Journal of cellular biochemistry, 1994, pp. 102-102
Risultati: 1-25 | 26-44