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Webster, KL
Maude, AB
O'Donnell, ME
Mehrotra, AP
Gani, D
Citation: Kl. Webster et al., Design and preparation of serine-threonine protein phosphatase inhibitors based upon the nodularin and microcystin toxin structures. Part 3, J CHEM S P1, (14), 2001, pp. 1673-1695
Citation: Me. O'Donnell et al., Serine-threonine protein phosphatase inhibitors derived from nodularin: role of the 2-methyl and 3-diene groups in the Adda residue and the effect ofmacrocyclic conformational restraint, J CHEM S P1, (14), 2001, pp. 1696-1708
Authors:
Sanvoisin, J
Pollard, JR
Hormozdiari, P
Ward, WHJ
Gani, D
Citation: J. Sanvoisin et al., A generic medium throughput activity assay procedure for serine-threonine protein phosphatases using C-14-labelled N-acetyl-Arg-Arg-Ala-Thr(P)-Val-Ala, J CHEM S P1, (14), 2001, pp. 1709-1715
Citation: J. Sanvoisin et D. Gani, Protein phosphatase 1 catalyses the direct hydrolytic cleavage of phosphate monoester in a ternary complex mechanism, BIOORG MED, 11(4), 2001, pp. 471-474
Authors:
Asuncion, M
Barlow, JN
Pollard, J
Staines, AG
McMahon, SA
Blankenfeldt, W
Gani, D
Naismith, JH
Citation: M. Asuncion et al., Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum, ACT CRYST D, 57, 2001, pp. 731-733
Authors:
Donnelly, MLL
Luke, G
Mehrotra, A
Li, XJ
Hughes, LE
Gani, D
Ryan, MD
Citation: Mll. Donnelly et al., Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putativeribosomal 'skip', J GEN VIROL, 82, 2001, pp. 1013-1025
Authors:
Donnelly, MLL
Hughes, LE
Luke, G
Mendoza, H
ten Dam, E
Gani, D
Ryan, MD
Citation: Mll. Donnelly et al., The 'cleavage' activities of foot-and-mouth disease virus 2A site-directedmutants and naturally occurring '2A-like' sequences, J GEN VIROL, 82, 2001, pp. 1027-1041
Citation: Dj. Miller et al., The 6-OH group of D-inositol 1-phosphate serves as an H-bond donor in the catalytic hydrolysis of the phosphate ester by inositol monsphosphatase, CHEMBIOCHEM, 1(4), 2000, pp. 262-271
Citation: Ap. Mehrotra et al., Synthesis of 6-dimethylamino-9-[3 '-(O-methyl) (2S)-[UL-C-14]-tyrosinylamino)-3 '-deoxy-beta-D-ribofuranosyl] purine, J LABEL C R, 43(6), 2000, pp. 623-634
Citation: J. Schulz et al., Synthesis of (+)-(1R,2R,4R,6S)-1,6-epoxy-4-benzyloxycyclohexan-2-ol, a keyprecursor to inositol monophosphatase inhibitors, from (-)-quinic acid, J CHEM S P1, (6), 2000, pp. 943-954
Citation: M. Akhtar et al., Solid-phase synthesis on functionalised fluoropolymer resins. Part 1: Nafion resin sulfonamide-immobilised carboxylic acid derivatives and aryl vinylsulfones, TETRAHEDR L, 41(22), 2000, pp. 4487-4491
Citation: Sy. Liu et al., Solid-phase synthesis on functionalised fluoropolymer resins. Part 2: Preparation and properties of functional Merrifield-type resins possessing a perfluorinated polymer backbone, TETRAHEDR L, 41(22), 2000, pp. 4493-4497
Authors:
Khayer, K
Jenn, T
Akhtar, M
John, R
Gani, D
Citation: K. Khayer et al., Synthesis of (R)- and (S)-2,3-diaminopropyl sulfate: mechanism based inhibition of glutamate 1-semialdehyde aminomutase, TETRAHEDR L, 41(10), 2000, pp. 1637-1641
Authors:
Contestabile, R
Jenn, T
Akhtar, M
Gani, D
John, RA
Citation: R. Contestabile et al., Reactions of glutamate 1-semialdehyde aminomutase with R- and S-enantiomers of a novel, mechanism-based inhibitor, 2,3-diaminopropyl sulfate, BIOCHEM, 39(11), 2000, pp. 3091-3096
Authors:
Pollard, JR
Richardson, S
Akhtar, M
Lasry, P
Neal, T
Botting, NP
Gani, D
Citation: Jr. Pollard et al., Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: Identification of an essential cysteine residue, BIO MED CH, 7(5), 1999, pp. 949-975
Authors:
Gani, D
Archer, CH
Botting, NP
Pollard, JR
Citation: D. Gani et al., The 3-methylaspartase reaction probed using H-2- and N-15-isotope effects for three substrates: A flip from a concerted to a carbocationic amino-enzyme elimination mechanism upon changing the C-3 stereochemistry in the substrate from R to S, BIO MED CH, 7(5), 1999, pp. 977-990
Authors:
Ryan, MD
Donnelly, M
Lewis, A
Mehrotra, AP
Wilkie, J
Gani, D
Citation: Md. Ryan et al., A model for nonstoichiometric, cotranslational protein scission in eukaryotic ribosomes, BIOORG CHEM, 27(1), 1999, pp. 55-79
Citation: N. Pitt et D. Gani, Synthesis and structure of a small marcocyclic hexapeptide model for antiparallel beta-sheet containing two restrained 2-(3 '-aminopropynyl)-aniline reverse-turn mimetics, TETRAHEDR L, 40(19), 1999, pp. 3811-3814
Citation: A. Lewis et al., Design, construction and properties of peptide N-terminal cap templates devised to initiate alpha-helices. Part 1. Caps derived from N-(4-chlorobutyryl)-(2S)-Pro-(2S)-Pro-(2S)-Ala-OMe and N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-hydroxyPro-OMe, J CHEM S P1, (22), 1998, pp. 3767-3775
Authors:
Lewis, A
Wilkie, J
Rutherford, TJ
Gani, D
Citation: A. Lewis et al., Design, construction and properties of peptide N-terminal cap templates devised to initiate alpha-helices. Part 2. Caps derived from N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-thioPro-OMe, J CHEM S P1, (22), 1998, pp. 3777-3793
Authors:
Lewis, A
Rutherford, TJ
Wilkie, J
Jenn, T
Gani, D
Citation: A. Lewis et al., Design, construction and properties of peptide N-terminal cap templates devised to initiate alpha-helices. Part 3. Caps derived from N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2R)-Ala-(2S,4S)-4-thioPro-OMe, J CHEM S P1, (22), 1998, pp. 3795-3806