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Results: 1-8 |
Results: 8
Synthesis of rofecoxib, (MK 0966, Vioxx((R)) 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2
Authors: Therien, M Gauthier, JY Leblanc, Y Leger, S Perrier, H Prasit, P Wang, ZI
Citation: M. Therien et al., Synthesis of rofecoxib, (MK 0966, Vioxx((R)) 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2, SYNTHESIS-S, (12), 2001, pp. 1778-1779
A class act
Authors: Gauthier, JY Agrawal, N
Citation: Jy. Gauthier et N. Agrawal, A class act, CHEM BRIT, 37(8), 2001, pp. 31-34
Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM))
Authors: Nicoll-Griffith, DA Yergey, JA Trimble, LA Silva, JM Li, C Chauret, N Gauthier, JY Grimm, E Leger, S Roy, P Therien, M Wang, ZY Prasit, P Zamboni, R Young, RN Brideau, C Chan, CC Mancini, J Riendeau, D
Citation: Da. Nicoll-griffith et al., Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM)), BIOORG MED, 10(23), 2000, pp. 2683-2686
A new structural variation on the methanesulfonylphenyl class of selectivecyclooxygenase-2 inhibitors
Authors: Li, CS Black, WC Brideau, C Chan, CC Charleson, S Cromlish, WA Claveau, D Gauthier, JY Gordon, R Greig, G Grimm, E Guay, J Lau, CK Riendeau, D Therien, M Visco, DM Wong, E Xu, LJ Prasit, P
Citation: Cs. Li et al., A new structural variation on the methanesulfonylphenyl class of selectivecyclooxygenase-2 inhibitors, BIOORG MED, 9(22), 1999, pp. 3181-3186
Synthesis and biological evaluation of 3-heteroarizoxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors
Authors: Lau, CK Brideau, C Chan, CC Charleson, S Cromlish, WA Ethier, D Gauthier, JY Gordon, R Guay, J Kargman, S Li, CS Prasit, P Riendeau, D Therien, M Visco, DM Xu, LJ
Citation: Ck. Lau et al., Synthesis and biological evaluation of 3-heteroarizoxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors, BIOORG MED, 9(22), 1999, pp. 3187-3192
The discovery of rofecoxib, [MK 966, Vioxx (R), 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor
Authors: Prasit, P Wang, Z Brideau, C Chan, CC Charleson, S Cromlish, W Ethier, D Evans, JF Ford-Hutchinson, AW Gauthier, JY Gordon, R Guay, J Gresser, M Kargman, S Kennedy, B Leblanc, Y Leger, S Mancini, J O'Neill, GP Ouellet, M Percival, MD Perrier, H Riendeau, D Rodger, I Tagari, P Therien, M Vickers, P Wong, E Xu, LJ Young, RN Zamboni, R Boyce, S Rupniak, N Forrest, N Visco, D Patrick, D
Citation: P. Prasit et al., The discovery of rofecoxib, [MK 966, Vioxx (R), 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor, BIOORG MED, 9(13), 1999, pp. 1773-1778
Rofecoxib [Vioxx, MK-0966; 4-(4 '-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
Authors: Chan, CC Boyce, S Brideau, C Charleson, S Cromlish, W Ethier, D Evans, J Ford-Hutchinson, AW Forrest, MJ Gauthier, JY Gordon, R Gresser, M Guay, J Kargman, S Kennedy, B Leblanc, Y Leger, S Mancini, J O'Neill, GP Ouellet, M Patrick, D Percival, MD Perrier, H Prasit, P Rodger, I Tagari, P Therien, M Vickers, P Visco, D Wang, Z Webb, J Wong, E Xu, LJ Young, RN Zamboni, R Riendeau, D
Citation: Cc. Chan et al., Rofecoxib [Vioxx, MK-0966; 4-(4 '-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles, J PHARM EXP, 290(2), 1999, pp. 551-560
Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe
Authors: Chauret, N Tremblay, N Lackman, RL Gauthier, JY Silva, JM Marois, J Yergey, JA Nicoll-Griffith, DA
Citation: N. Chauret et al., Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe, ANALYT BIOC, 276(2), 1999, pp. 215-226
Risultati: 1-8 |