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Results: 1-7 |
Results: 7
Farnesyl protein transferase inhibition: A novel approach to anti-tumor therapy. The discovery and development of SCH 66336
Authors: Ganguly, AK Doll, RJ Girijavallabhan, VM
Citation: Ak. Ganguly et al., Farnesyl protein transferase inhibition: A novel approach to anti-tumor therapy. The discovery and development of SCH 66336, CURR MED CH, 8(12), 2001, pp. 1419-1436
Enzymatic kinetic resolution of piperidine atropisomers: Synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336
Authors: Morgan, B Zaks, A Dodds, DR Liu, JC Jain, R Megati, S Njoroge, FG Girijavallabhan, VM
Citation: B. Morgan et al., Enzymatic kinetic resolution of piperidine atropisomers: Synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336, J ORG CHEM, 65(18), 2000, pp. 5451-5459
Structural characterization of the oligosaccharide antibiotics everninomicins by negative ion FAB and ESI/MS
Authors: Pramanik, BN Shipkova, PA Bartner, PL Heimark, L Liu, YH Das, PR Saksena, AK Sarre, OZ Girijavallabhan, VM Ganguly, AK
Citation: Bn. Pramanik et al., Structural characterization of the oligosaccharide antibiotics everninomicins by negative ion FAB and ESI/MS, J ANTIBIOT, 53(6), 2000, pp. 640-643
Atropisomeric trihalobenzocycloheptapyridine analogues provide stereoselective FPT inhibitors with antitumor activity
Authors: Njoroge, FG Vibulbhan, B Bishop, WR Kirschmeier, P Bryant, MS Nomeir, AA Liu, M Doll, RJ Girijavallabhan, VM Ganguly, AK
Citation: Fg. Njoroge et al., Atropisomeric trihalobenzocycloheptapyridine analogues provide stereoselective FPT inhibitors with antitumor activity, BIO MED CH, 7(5), 1999, pp. 861-867
Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice
Authors: Liu, M Bryant, MS Chen, JP Lee, SN Yaremko, B Li, ZJ Dell, J Lipari, P Malkowski, M Prioli, N Rossman, RR Korfmacher, WA Nomeir, AA Lin, CC Mallams, AK Doll, RJ Catino, JJ Girijavallabhan, VM Kirschmeier, P Bishop, WR
Citation: M. Liu et al., Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice, CANC CHEMOT, 43(1), 1999, pp. 50-58
Identification of pharmacokinetically stable 3,10-dibromo-8-chlorobenzocycloheptapyridine farnesyl protein transferase inhibitors with potent enzyme and cellular activities
Authors: Taveras, AG Deskus, J Chao, JP Vaccaro, CJ Njoroge, FG Vibulbhan, B Pinto, P Remiszewski, S del Rosario, J Doll, RJ Alvarez, C Lalwani, T Mallams, AK Rossman, RR Afonso, A Girijavallabhan, VM Ganguly, AK Pramanik, B Heimark, L Bishop, WR Wang, L Kirschmeier, P James, L Carr, D Patton, R Bryant, MS Nomeir, AA Liu, M
Citation: Ag. Taveras et al., Identification of pharmacokinetically stable 3,10-dibromo-8-chlorobenzocycloheptapyridine farnesyl protein transferase inhibitors with potent enzyme and cellular activities, J MED CHEM, 42(14), 1999, pp. 2651-2661
Tricyclic farnesyl protein transferase inhibitors: Crystallographic and calorimetric studies of structure-activity relationships
Authors: Strickland, CL Weber, PC Windsor, WT Wu, Z Le, HV Albanese, MM Alvarez, CS Cesarz, D del Rosario, J Deskus, J Mallams, AK Njoroge, FG Piwinski, JJ Remiszewski, S Rossman, RR Taveras, AG Vibulbhan, B Doll, RJ Girijavallabhan, VM Ganguly, AK
Citation: Cl. Strickland et al., Tricyclic farnesyl protein transferase inhibitors: Crystallographic and calorimetric studies of structure-activity relationships, J MED CHEM, 42(12), 1999, pp. 2125-2135
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