AAAAAA

   
Results: 1-25 | 26-28
Results: 1-25/28
Crossed acyloin condensation of aliphatic aldehydes
Authors: Heck, R Henderson, AP Kohler, B Retey, J Golding, BT
Citation: R. Heck et al., Crossed acyloin condensation of aliphatic aldehydes, EUR J ORG C, (14), 2001, pp. 2623-2627
In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity
Authors: Smith, PG Thomas, HD Barlow, HC Griffin, RJ Golding, BT Calvert, AH Newell, DR Curtin, NJ
Citation: Pg. Smith et al., In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity, CLIN CANC R, 7(7), 2001, pp. 2105-2113
Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035)
Authors: Stockley, M Clegg, W Fontana, G Golding, BT Martin, N Rigoreau, LJM Smith, GCM Griffin, RJ
Citation: M. Stockley et al., Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035), BIOORG MED, 11(21), 2001, pp. 2837-2841
In vitro metabolism of chloroprene: Species differences, epoxide stereochemistry and a de-chlorination pathway
Authors: Cottrell, L Golding, BT Munter, T Watson, WP
Citation: L. Cottrell et al., In vitro metabolism of chloroprene: Species differences, epoxide stereochemistry and a de-chlorination pathway, CHEM RES T, 14(11), 2001, pp. 1552-1562
Metabolism and molecular toxicology of isoprene
Authors: Watson, WP Cottrell, L Zhang, DP Golding, BT
Citation: Wp. Watson et al., Metabolism and molecular toxicology of isoprene, CHEM-BIO IN, 135, 2001, pp. 223-238
Understanding the mechanism of B-12-dependent diol dehydratase: A synergistic retro-push-pull proposal
Authors: Smith, DM Golding, BT Radom, L
Citation: Dm. Smith et al., Understanding the mechanism of B-12-dependent diol dehydratase: A synergistic retro-push-pull proposal, J AM CHEM S, 123(8), 2001, pp. 1664-1675
Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: A distinctive B-12-dependent carbon-skeleton rearrangement
Authors: Wetmore, SD Smith, DM Golding, BT Radom, L
Citation: Sd. Wetmore et al., Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: A distinctive B-12-dependent carbon-skeleton rearrangement, J AM CHEM S, 123(33), 2001, pp. 7963-7972
Intramolecular functionalisation by a methylene radical of a 1,2-diol and a vicinal amino alcohol: models for coenzyme B-12-dependent diol dehydratase and ethanolamine ammonia lyase
Authors: Anderson, RJ Ashwell, S Garnett, I Golding, BT
Citation: Rj. Anderson et al., Intramolecular functionalisation by a methylene radical of a 1,2-diol and a vicinal amino alcohol: models for coenzyme B-12-dependent diol dehydratase and ethanolamine ammonia lyase, J CHEM S P1, (24), 2000, pp. 4488-4498
Atmospheric chemistry of toluene-1,2-oxide/2-methyloxepin
Authors: Klotz, B Barnes, I Golding, BT Becker, KH
Citation: B. Klotz et al., Atmospheric chemistry of toluene-1,2-oxide/2-methyloxepin, PCCP PHYS C, 2(2), 2000, pp. 227-235
Synthesis of enantiopure isoprene epoxides from (S)-lactic acid via 'dispoke' intermediates
Authors: Zhang, DP Bleasdale, C Golding, BT Watson, WP
Citation: Dp. Zhang et al., Synthesis of enantiopure isoprene epoxides from (S)-lactic acid via 'dispoke' intermediates, CHEM COMMUN, (13), 2000, pp. 1141-1142
Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP)
Authors: Barlow, HC Bowman, KJ Curtin, NJ Calvert, AH Golding, BT Huang, B Loughlin, PJ Newell, DR Smith, PG Griffin, RJ
Citation: Hc. Barlow et al., Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP), BIOORG MED, 10(6), 2000, pp. 585-589
Transalkylation of phosphotriesters using cob(I)alamin: Toward specific determination of DNA-phosphate adducts
Authors: Haglund, J Rafiq, A Ehrenberg, L Golding, BT Tornqvist, M
Citation: J. Haglund et al., Transalkylation of phosphotriesters using cob(I)alamin: Toward specific determination of DNA-phosphate adducts, CHEM RES T, 13(4), 2000, pp. 253-256
A convenient preparation of p-metboxybenzyl esters
Authors: Wang, MF Golding, BT Potter, GA
Citation: Mf. Wang et al., A convenient preparation of p-metboxybenzyl esters, SYN COMMUN, 30(23), 2000, pp. 4197-4204
Resistance-modifying agents. 8. Inhibition of O-6-alkylguanine-DNA alkyltransferase by O-6-alkenyl-, O-6-cycloalkenyl-, and O-6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O-6-(1-cyclopentenylmethyl)guanine
Authors: Griffin, RJ Arris, CE Bleasdale, C Boyle, FT Calvert, AH Curtin, NJ Dalby, C Kanugula, S Lembicz, NK Newell, DR Pegg, AE Golding, BT
Citation: Rj. Griffin et al., Resistance-modifying agents. 8. Inhibition of O-6-alkylguanine-DNA alkyltransferase by O-6-alkenyl-, O-6-cycloalkenyl-, and O-6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O-6-(1-cyclopentenylmethyl)guanine, J MED CHEM, 43(22), 2000, pp. 4071-4083
Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase
Authors: White, AW Almassy, R Calvert, AH Curtin, NJ Griffin, RJ Hostomsky, Z Maegley, K Newell, DR Srinivasan, S Golding, BT
Citation: Aw. White et al., Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase, J MED CHEM, 43(22), 2000, pp. 4084-4097
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
Authors: Arris, CE Boyle, FT Calvert, AH Curtin, NJ Endicott, JA Garman, EF Gibson, AE Golding, BT Grant, S Griffin, RJ Jewsbury, P Johnson, LN Lawrie, AM Newell, DR Noble, MEM Sausville, EA Schultz, R Yu, W
Citation: Ce. Arris et al., Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles, J MED CHEM, 43(15), 2000, pp. 2797-2804
Stereochemistry of the methyl group in (R)-3-methylitaconate derived by rearrangement of 2-methylideneglutarate catalysed by a coenzyme B-12-dependent mutase
Authors: Ciceri, D Pierik, AJ Hartrampf, G Broker, G Speranza, G Buckel, W Cornforth, J Golding, BT
Citation: D. Ciceri et al., Stereochemistry of the methyl group in (R)-3-methylitaconate derived by rearrangement of 2-methylideneglutarate catalysed by a coenzyme B-12-dependent mutase, HELV CHIM A, 83(9), 2000, pp. 2550-2561
Synthesis of 3-alkoxy- and 3-alkylamino-2-alkyl-3-arylisoindolinones
Authors: Kitching, MS Clegg, W Elsegood, MRJ Griffin, RJ Golding, BT
Citation: Ms. Kitching et al., Synthesis of 3-alkoxy- and 3-alkylamino-2-alkyl-3-arylisoindolinones, SYNLETT, 1999, pp. 997-999
Protecting-group strategies for the synthesis of N-4-substituted and N-1,N-8-disubstituted spermidines, exemplified by hirudonine
Authors: Golding, BT Mitchinson, A Clegg, W Elsegood, MRJ Griffin, RJ
Citation: Bt. Golding et al., Protecting-group strategies for the synthesis of N-4-substituted and N-1,N-8-disubstituted spermidines, exemplified by hirudonine, J CHEM S P1, (3), 1999, pp. 349-356
Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced alpha(1)-acid glycoprotein binding
Authors: Curtin, NJ Bowman, KJ Turner, RN Huang, B Loughlin, PJ Calvert, AH Golding, BT Griffin, RJ Newell, DR
Citation: Nj. Curtin et al., Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced alpha(1)-acid glycoprotein binding, BR J CANC, 80(11), 1999, pp. 1738-1746
Facilitation of enzyme-catalyzed reactions by partial proton transfer: Application to coenzyme-B-12-dependent methylmalonyl-CoA mutase
Authors: Smith, DM Golding, BT Radom, L
Citation: Dm. Smith et al., Facilitation of enzyme-catalyzed reactions by partial proton transfer: Application to coenzyme-B-12-dependent methylmalonyl-CoA mutase, J AM CHEM S, 121(6), 1999, pp. 1383-1384
On the mechanism of action of vitamin B-12: Theoretical studies of the 2-methyleneglutarate mutase catalyzed rearrangement
Authors: Smith, DM Golding, BT Radom, L
Citation: Dm. Smith et al., On the mechanism of action of vitamin B-12: Theoretical studies of the 2-methyleneglutarate mutase catalyzed rearrangement, J AM CHEM S, 121(5), 1999, pp. 1037-1044
Understanding the mechanism of B-12-dependent methylmalonyl-CoA mutase: Partial proton transfer in action
Authors: Smith, DM Golding, BT Radom, L
Citation: Dm. Smith et al., Understanding the mechanism of B-12-dependent methylmalonyl-CoA mutase: Partial proton transfer in action, J AM CHEM S, 121(40), 1999, pp. 9388-9399
Toward a consistent mechanism for diol dehydratase catalyzed reactions: Anapplication of the partial-proton-transfer concept
Authors: Smith, DM Golding, BT Radom, L
Citation: Dm. Smith et al., Toward a consistent mechanism for diol dehydratase catalyzed reactions: Anapplication of the partial-proton-transfer concept, J AM CHEM S, 121(24), 1999, pp. 5700-5704
Remarkable cleavage of molecular hydrogen without the use of metallic catalysts: a theoretical investigation
Authors: Scott, AP Golding, BT Radom, L
Citation: Ap. Scott et al., Remarkable cleavage of molecular hydrogen without the use of metallic catalysts: a theoretical investigation, NEW J CHEM, 22(11), 1998, pp. 1171-1173
Risultati: 1-25 | 26-28