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Results: 51-75/110
IDENTIFICATION OF CYSTEINE-354 OF BETA-TUBULIN AS PART OF THE BINDING-SITE FOR THE A-RING OF COLCHICINE
Authors: BAI RL PEI XF BOYE O GETAHUN Z GROVER S BEKISZ J NGUYEN NY BROSSI A HAMEL E
Citation: Rl. Bai et al., IDENTIFICATION OF CYSTEINE-354 OF BETA-TUBULIN AS PART OF THE BINDING-SITE FOR THE A-RING OF COLCHICINE, The Journal of biological chemistry, 271(21), 1996, pp. 12639-12645
CHARACTERIZATION OF THE INTERACTION OF CRYPTOPHYCIN-1 WITH TUBULIN - BINDING IN THE VINCA DOMAIN, COMPETITIVE-INHIBITION OF DOLASTATIN-10 BINDING, AND AN UNUSUAL AGGREGATION REACTION
Authors: BAI RL SCHWARTZ RE KEPLER JA PETTIT GR HAMEL E
Citation: Rl. Bai et al., CHARACTERIZATION OF THE INTERACTION OF CRYPTOPHYCIN-1 WITH TUBULIN - BINDING IN THE VINCA DOMAIN, COMPETITIVE-INHIBITION OF DOLASTATIN-10 BINDING, AND AN UNUSUAL AGGREGATION REACTION, Cancer research, 56(19), 1996, pp. 4398-4406
IPSILATERAL ALTERATIONS IN TRYPTOPHAN-HYDROXYLASE ACTIVITY IN RAT-BRAIN AFTER HYPOTHALAMIC 5,7-DI-HYDROXYTRYPTAMINE LESION
Authors: LJUBICTHIBAL V DIKSIC M HAMEL E RAISON S PUJOL JF WEISSMANN D
Citation: V. Ljubicthibal et al., IPSILATERAL ALTERATIONS IN TRYPTOPHAN-HYDROXYLASE ACTIVITY IN RAT-BRAIN AFTER HYPOTHALAMIC 5,7-DI-HYDROXYTRYPTAMINE LESION, Brain research, 724(2), 1996, pp. 222-231
INTERACTIONS OF 2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE, WITH UNPOLYMERIZED TUBULIN AND WITH TUBULIN POLYMERS
Authors: HAMEL E LIN CM FLYNN E DAMATO RJ
Citation: E. Hamel et al., INTERACTIONS OF 2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE, WITH UNPOLYMERIZED TUBULIN AND WITH TUBULIN POLYMERS, Biochemistry, 35(4), 1996, pp. 1304-1310
DISCODERMOLIDE, A CYTOTOXIC MARINE AGENT THAT STABILIZES MICROTUBULESMORE POTENTLY THAN TAXOL
Authors: TERHAAR E KOWALSKI RJ HAMEL E LIN CM LONGLEY RE GUNASEKERA SP ROSENKRANZ HS DAY BW
Citation: E. Terhaar et al., DISCODERMOLIDE, A CYTOTOXIC MARINE AGENT THAT STABILIZES MICROTUBULESMORE POTENTLY THAN TAXOL, Biochemistry, 35(1), 1996, pp. 243-250
ANTITUMOR 2,3-DIHYDRO-2-(ARYL)-4(1H)-QUINAZOLINONE DERIVATIVES - INTERACTIONS WITH TUBULIN
Authors: HAMEL E LIN CM PLOWMAN J WANG HK LEE KH PAULL KD
Citation: E. Hamel et al., ANTITUMOR 2,3-DIHYDRO-2-(ARYL)-4(1H)-QUINAZOLINONE DERIVATIVES - INTERACTIONS WITH TUBULIN, Biochemical pharmacology, 51(1), 1996, pp. 53-59
INTERACTIONS OF TUBULIN WITH GUANINE-NUCLEOTIDES THAT HAVE PACLITAXEL-LIKE EFFECTS ON TUBULIN ASSEMBLY
Authors: VAUGHNS J GETAHUN Z JOHNSON R LIN CM HAMEL E
Citation: J. Vaughns et al., INTERACTIONS OF TUBULIN WITH GUANINE-NUCLEOTIDES THAT HAVE PACLITAXEL-LIKE EFFECTS ON TUBULIN ASSEMBLY, Molecular biology of the cell, 6, 1995, pp. 169-169
COMPARISON OF NOVEL MICROTUBULE POLYMERIZING AGENTS, DLSCODERMOLIDE AND EPOTHILONE A B, WITH TAXOL/
Authors: KOWALSKI RJ TERHAAR E LONGLEY RE GUNASEKERA SP LIN CM DAY BV HAMEL E
Citation: Rj. Kowalski et al., COMPARISON OF NOVEL MICROTUBULE POLYMERIZING AGENTS, DLSCODERMOLIDE AND EPOTHILONE A B, WITH TAXOL/, Molecular biology of the cell, 6, 1995, pp. 2137-2137
THE RECEPTOR-BINDING AND VASCULAR IN-VITRO PHARMACOLOGICAL PROFILE OFBMS-180048, A NOVEL ANTIMIGRAINE AGENT
Authors: SARBIN NS GYLYS JA IBEN LG MAHLE CD IZZARELLI DG PARKER EM NOONAN JW WILLIAMS AD SMITH DW HAMEL E YOCCA FD
Citation: Ns. Sarbin et al., THE RECEPTOR-BINDING AND VASCULAR IN-VITRO PHARMACOLOGICAL PROFILE OFBMS-180048, A NOVEL ANTIMIGRAINE AGENT, The FASEB journal, 9(3), 1995, pp. 347-347
IN-VIVO SYNTHESIZED RADIOACTIVELY LABELED ALPHA-METHYL SEROTONIN AS ASELECTIVE TRACER FOR VISUALIZATION OF BRAIN-SEROTONIN NEURONS
Authors: COHEN Z TSUIKI K TAKADA A BEAUDET A DIKSIC M HAMEL E
Citation: Z. Cohen et al., IN-VIVO SYNTHESIZED RADIOACTIVELY LABELED ALPHA-METHYL SEROTONIN AS ASELECTIVE TRACER FOR VISUALIZATION OF BRAIN-SEROTONIN NEURONS, Synapse, 21(1), 1995, pp. 21-28
ULTRASTRUCTURAL ANALYSIS OF TRYPTOPHAN-HYDROXYLASE IMMUNOREACTIVE NERVE-TERMINALS IN THE RAT CEREBRAL-CORTEX AND HIPPOCAMPUS - THEIR ASSOCIATIONS WITH LOCAL BLOOD-VESSELS
Authors: COHEN Z EHRET M MAITRE M HAMEL E
Citation: Z. Cohen et al., ULTRASTRUCTURAL ANALYSIS OF TRYPTOPHAN-HYDROXYLASE IMMUNOREACTIVE NERVE-TERMINALS IN THE RAT CEREBRAL-CORTEX AND HIPPOCAMPUS - THEIR ASSOCIATIONS WITH LOCAL BLOOD-VESSELS, Neuroscience, 66(3), 1995, pp. 555-569
LIMITATIONS IN THE USE OF TUBULIN POLYMERIZATION ASSAYS AS A SCREEN FOR THE IDENTIFICATION OF NEW ANTIMITOTIC AGENTS - THE POTENT MARINE NATURAL PRODUCT CURACIN-A AS AN EXAMPLE
Authors: HAMEL E BLOKHIN AV NAGLE DG YOO HD GERWICK WH
Citation: E. Hamel et al., LIMITATIONS IN THE USE OF TUBULIN POLYMERIZATION ASSAYS AS A SCREEN FOR THE IDENTIFICATION OF NEW ANTIMITOTIC AGENTS - THE POTENT MARINE NATURAL PRODUCT CURACIN-A AS AN EXAMPLE, Drug development research, 34(2), 1995, pp. 110-120
CHOLINERGIC BASAL FOREBRAIN NEURONS PROJECT TO CORTICAL MICROVESSELS IN THE RAT - ELECTRON-MICROSCOPIC STUDY WITH ANTEROGRADELY TRANSPORTEDPHASEOLUS-VULGARIS-LEUKOAGGLUTININ AND CHOLINE-ACETYLTRANSFERASE IMMUNOCYTOCHEMISTRY
Authors: VAUCHER E HAMEL E
Citation: E. Vaucher et E. Hamel, CHOLINERGIC BASAL FOREBRAIN NEURONS PROJECT TO CORTICAL MICROVESSELS IN THE RAT - ELECTRON-MICROSCOPIC STUDY WITH ANTEROGRADELY TRANSPORTEDPHASEOLUS-VULGARIS-LEUKOAGGLUTININ AND CHOLINE-ACETYLTRANSFERASE IMMUNOCYTOCHEMISTRY, The Journal of neuroscience, 15(11), 1995, pp. 7427-7441
ANTINEOPLASTIC AGENTS .337. SYNTHESIS OF DOLASTATIN-10 STRUCTURAL MODIFICATIONS
Authors: PETTIT GR SRIRANGAM JK BARKOCZY J WILLIAMS MD DURKIN KPM BOYD MR BAI RL HAMEL E SCHMIDT JM CHAPUIS JC
Citation: Gr. Pettit et al., ANTINEOPLASTIC AGENTS .337. SYNTHESIS OF DOLASTATIN-10 STRUCTURAL MODIFICATIONS, Anti-cancer drug design, 10(7), 1995, pp. 529-544
ANTITUMOR AGENTS .154. CYTOTOXIC AND ANTIMITOTIC FLAVONOLS FROM POLANISIA-DODECANDRA
Authors: SHI Q CHEN K LI LP CHANG JJ AUTRY C KOZUKA M KONOSHIMA T ESTES JR LIN CM HAMEL E MCPHAIL AT MCPHAIL DR LEE KH
Citation: Q. Shi et al., ANTITUMOR AGENTS .154. CYTOTOXIC AND ANTIMITOTIC FLAVONOLS FROM POLANISIA-DODECANDRA, Journal of natural products, 58(4), 1995, pp. 475-482
SYNTHESIS AND BIOLOGICAL EVALUATION OF PACLITAXEL ANALOGS MODIFIED INRING-C
Authors: LIANG XA KINGSTON DGI LIN CM HAMEL E
Citation: Xa. Liang et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF PACLITAXEL ANALOGS MODIFIED INRING-C, Tetrahedron letters, 36(17), 1995, pp. 2901-2904
PHARMACOLOGICAL CHARACTERIZATION OF MUSCARINIC ACETYLCHOLINE BINDING-SITES IN HUMAN AND BOVINE CEREBRAL MICROVESSELS
Authors: LINVILLE DG HAMEL E
Citation: Dg. Linville et E. Hamel, PHARMACOLOGICAL CHARACTERIZATION OF MUSCARINIC ACETYLCHOLINE BINDING-SITES IN HUMAN AND BOVINE CEREBRAL MICROVESSELS, Naunyn-Schmiedeberg's archives of pharmacology, 352(2), 1995, pp. 179-186
CHARACTERIZATION OF THE INTERACTION OF THE MARINE CYANOBACTERIAL NATURAL PRODUCT CURACIN-A WITH THE COLCHICINE SITE OF TUBULIN AND INITIAL STRUCTURE-ACTIVITY STUDIES WITH ANALOGS
Authors: BLOKHIN AV YOO HD GERALDS RS NAGLE DG GERWICK WH HAMEL E
Citation: Av. Blokhin et al., CHARACTERIZATION OF THE INTERACTION OF THE MARINE CYANOBACTERIAL NATURAL PRODUCT CURACIN-A WITH THE COLCHICINE SITE OF TUBULIN AND INITIAL STRUCTURE-ACTIVITY STUDIES WITH ANALOGS, Molecular pharmacology, 48(3), 1995, pp. 523-531
INTERACTION OF DOLASTATIN-10 WITH TUBULIN - INDUCTION OF AGGREGATION AND BINDING AND DISSOCIATION REACTIONS
Authors: BAI RL TAYLOR GF SCHMIDT JM WILIAMS MD KEPLER JA PETTIT GR HAMEL E
Citation: Rl. Bai et al., INTERACTION OF DOLASTATIN-10 WITH TUBULIN - INDUCTION OF AGGREGATION AND BINDING AND DISSOCIATION REACTIONS, Molecular pharmacology, 47(5), 1995, pp. 965-976
ANTINEOPLASTIC AGENTS .291. ISOLATION AND SYNTHESIS OF COMBRETASTATINS A-4, A-5, AND A-6 (VOL 38, PG 1666, 1995)
Authors: PETTIT GR SINGH SB BOYD MR HAMEL E PETTIT RK SCHMIDT JM HOGAN F
Citation: Gr. Pettit et al., ANTINEOPLASTIC AGENTS .291. ISOLATION AND SYNTHESIS OF COMBRETASTATINS A-4, A-5, AND A-6 (VOL 38, PG 1666, 1995), Journal of medicinal chemistry, 38(15), 1995, pp. 2994-2994
SYNTHESIS, ANTITUBULIN AND ANTIMITOTIC ACTIVITY, AND CYTOTOXICITY OF ANALOGS OF 2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE OF ESTRADIOL THAT INHIBITS TUBULIN POLYMERIZATION BY BINDING TO THE COLCHICINE BINDING-SITE
Authors: CUSHMAN M HE HM KATZENELLENBOGEN JA LIN CM HAMEL E
Citation: M. Cushman et al., SYNTHESIS, ANTITUBULIN AND ANTIMITOTIC ACTIVITY, AND CYTOTOXICITY OF ANALOGS OF 2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE OF ESTRADIOL THAT INHIBITS TUBULIN POLYMERIZATION BY BINDING TO THE COLCHICINE BINDING-SITE, Journal of medicinal chemistry, 38(12), 1995, pp. 2041-2049
ANTINEOPLASTIC AGENTS .291. ISOLATION AND SYNTHESIS OF COMBRETASTATINS A-4, A-5, AND A-6
Authors: PETTIT GR SINGH SB BOYD MR HAMEL E PETTIT RK SCHMIDT JM HOGAN F
Citation: Gr. Pettit et al., ANTINEOPLASTIC AGENTS .291. ISOLATION AND SYNTHESIS OF COMBRETASTATINS A-4, A-5, AND A-6, Journal of medicinal chemistry, 38(10), 1995, pp. 1666-1672
CHARACTERIZATION OF NEUROPEPTIDE-Y (NPY) RECEPTORS IN HUMAN CEREBRAL-ARTERIES WITH SELECTIVE AGONISTS AND THE NEW Y-1 ANTAGONIST BIBP-3226
Authors: ABOUNADER R VILLEMURE JG HAMEL E
Citation: R. Abounader et al., CHARACTERIZATION OF NEUROPEPTIDE-Y (NPY) RECEPTORS IN HUMAN CEREBRAL-ARTERIES WITH SELECTIVE AGONISTS AND THE NEW Y-1 ANTAGONIST BIBP-3226, British Journal of Pharmacology, 116(4), 1995, pp. 2245-2250
THE SPONGISTATINS, POTENTLY CYTOTOXIC INHIBITORS OF TUBULIN POLYMERIZATION, BIND IN A DISTINCT REGION OF THE VINCA DOMAIN
Authors: BAI RL TAYLOR GF CICHACZ ZA HERALD CL KEPLER JA PETTIT GR HAMEL E
Citation: Rl. Bai et al., THE SPONGISTATINS, POTENTLY CYTOTOXIC INHIBITORS OF TUBULIN POLYMERIZATION, BIND IN A DISTINCT REGION OF THE VINCA DOMAIN, Biochemistry, 34(30), 1995, pp. 9714-9721
DIFFERENTIAL-EFFECTS OF PACLITAXEL (TAXOL) ANALOGS MODIFIED AT POSITIONS C-2, C-7, AND C-3' ON TUBULIN POLYMERIZATION AND POLYMER STABILIZATION - IDENTIFICATION OF A HYPERACTIVE PACLITAXEL DERIVATIVE
Authors: GROVER S RIMOLDI JM MOLINERO AA CHAUDHARY AG KINGSTON DGI HAMEL E
Citation: S. Grover et al., DIFFERENTIAL-EFFECTS OF PACLITAXEL (TAXOL) ANALOGS MODIFIED AT POSITIONS C-2, C-7, AND C-3' ON TUBULIN POLYMERIZATION AND POLYMER STABILIZATION - IDENTIFICATION OF A HYPERACTIVE PACLITAXEL DERIVATIVE, Biochemistry, 34(12), 1995, pp. 3927-3934
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