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Results:
1-20
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Results: 20
Authors:
ROSING H
HILLEBRAND MJX
JIMENO JM
GOMEZ A
FLORIANO P
FAIRCLOTH G
CAMERON L
HENRAR REC
VERMORKEN JB
BULT A
BEIJNEN JH
Citation: H. Rosing et al., ANALYSIS OF ECTEINASCIDIN-743, A NEW POTENT MARINE-DERIVED ANTICANCERDRUG, IN HUMAN PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN COMBINATION WITH SOLID-PHASE EXTRACTION, Journal of chromatography B. Biomedical sciences and applications, 710(1-2), 1998, pp. 183-189
Authors:
ROSING H
HILLEBRAND MJX
JIMENO JM
GOMEZ A
FLORIANO P
FAIRCLOTH G
HENRAR REC
VERMORKEN JB
CVITKOVIC E
BULT A
BEIJNEN JH
Citation: H. Rosing et al., QUANTITATIVE-DETERMINATION OF ECTEINASCIDIN-743 IN HUMAN PLASMA BY MINIATURIZED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY COUPLED WITH ELECTROSPRAY-IONIZATION TANDEM MASS-SPECTROMETRY, Journal of mass spectrometry, 33(11), 1998, pp. 1134-1140
Authors:
MASTBERGEN SC
HENRAR REC
FAIRCLOTH G
GELDOF AA
Citation: Sc. Mastbergen et al., CYTOTOXICITY AND NEUROCYTOTOXICITY OF APLIDINE, A NEW MARINE ANTICANCER AGENT EVALUATED USING IN-VITRO ASSAYS, Annals of oncology, 9, 1998, pp. 131-131
Authors:
NUYEN B
HENRAR REC
GOMEZ A
BEIJNEN JH
Citation: B. Nuyen et al., PHARMACEUTICAL DEVELOPMENT OF A PARENTERAL LYOPHILIZED FORMULATION OFTHE NOVEL ANTITUMOR AGENT APLIDINE (DEHYDRODIDEMNIN-B), Annals of oncology, 9, 1998, pp. 180-180
Authors:
SPARIDANS RW
HENRAR REC
JIMENO J
FAIRCLOTH C
FLORIANO P
BEIJNEN JH
Citation: Rw. Sparidans et al., BIOANALYSIS OF APLIDINE, A NEW MARINE ANTITUMOR DEPSIPEPTIDE, IN PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AFTER DERIVATIZATION WITH4'-HYDRAZINO-2-STILBAZOLE, Annals of oncology, 9, 1998, pp. 192-192
Authors:
VANTELLINGEN O
SCHAAF LJ
PUNT CJA
AWADA A
VANDERVALK M
HENRAR REC
WAGENER DJT
PICCART MJ
NOOIJEN WJ
BEIJNEN JH
Citation: O. Vantellingen et al., IN-VITRO AND IN-VIVO BONE-MARROW TOXICITY ASSAYS IN THE CLINICAL DEVELOPMENT OF NEW DRUGS - CARZELESIN AS AN EXAMPLE, Annals of oncology, 9, 1998, pp. 204-204
Authors:
ROSING H
HILLEBRAND MJX
JIMENO JM
GOMEZ A
FLORIANO P
FAIRCLOTH G
HENRAR REC
VERMORKEN JB
CVITKOVIC E
VILLALONA M
BULT A
BEIJNEN JH
Citation: H. Rosing et al., DETERMINATION OF ECTEINASCIDIN-743 IN HUMAN PLASMA - COMPARISON OF CONVENTIONAL LC UV TO MINIATURIZED LC ELECTROSPRAY-IONIZATION TANDEM MASS-SPECTROMETRY/, Annals of oncology, 9, 1998, pp. 454-454
Authors:
VANTELLINGEN O
PUNT CJA
AWADA A
WAGENER DJT
PICCART MJ
GROOT Y
SCHAAF LJ
HENRAR REC
NOOIJEN WJ
BEIJNEN JH
Citation: O. Vantellingen et al., A CLINICAL PHARMACOKINETICS STUDY OF CARZELESIN GIVEN BY SHORT-TERM INTRAVENOUS-INFUSION IN A PHASE-I STUDY, Cancer chemotherapy and pharmacology, 41(5), 1998, pp. 377-384
Authors:
JONKMANDEVRIES JD
ROSING H
TALSMA H
HENRAR REC
KETTENESVANDENBOSCH JJ
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., PHARMACEUTICAL DEVELOPMENT OF A PARENTERAL LYOPHILIZED FORMULATION OFTHE INVESTIGATIONAL ANTITUMOR NEUROPEPTIDE ANTAGONIST [ARG(6), D-TRP(7,9), MEPHE(8)]-SUBSTANCE P (6-11), Investigational new drugs, 16(2), 1998, pp. 99-111
Authors:
VANTELLINGEN O
NOOIJEN WJ
SCHAAF LJ
VANDERVALK M
VANASPEREN J
HENRAR REC
BEIJNEN JH
Citation: O. Vantellingen et al., COMPARATIVE PHARMACOLOGY OF THE NOVEL CYCLOPROPYLPYRROLOINDOLE-PRODRUG CARZELESIN IN MICE, RATS, AND HUMANS, Cancer research, 58(11), 1998, pp. 2410-2416
Authors:
JONKMANDEVRIES JD
HENRAR REC
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., MANUFACTURING OF A LYOPHILIZED PARENTERAL DOSAGE FORM OF THE INDOLOQUINONE ANTITUMOR AGENT EO9 FOR PHASE-II CLINICAL-STUDIES IN THE SETTINGOF A HOSPITAL PHARMACY, Drug development and industrial pharmacy, 23(2), 1997, pp. 137-144
Authors:
HENRAR REC
Citation: Rec. Henrar, FILING OF EORTC SOPS AT FDA WILL SPEED APPROVAL OF DRUGS FROM EUROPE, European journal of cancer, 32A(3), 1996, pp. 389-389
Authors:
JONKMANDEVRIES JD
KETTENESVANDENBOSCH JJ
HENRAR REC
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., PURITY DETERMINATIONS IN THE BULK DRUG OF THE NOVEL INDOLOQUINONE ANTITUMOR AGENT EO9, Investigational new drugs, 14(2), 1996, pp. 181-191
Authors:
JONKMANDEVRIES JD
DOPPENBERG WG
HENRAR REC
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., SYSTEMATIC STUDY ON THE CHEMICAL-STABILITY OF THE PRODRUG ANTITUMOR AGENT CARZELESIN (U-80,244), Journal of pharmaceutical sciences, 85(11), 1996, pp. 1227-1233
Authors:
BURTLES SS
NEWELL DR
HENRAR REC
CONNERS TA
Citation: Ss. Burtles et al., REVISIONS OF GENERAL-GUIDELINES FOR THE PRECLINICAL TOXICOLOGY OF NEWCYTOTOXIC ANTICANCER AGENTS IN EUROPE, European journal of cancer, 31A(3), 1995, pp. 408-410
Authors:
BEIJNEN JH
FLORA KP
HALBERT GW
HENRAR REC
SLACK JA
Citation: Jh. Beijnen et al., CRC EORTC/NCI JOINT FORMULATION WORKING PARTY - EXPERIENCES IN THE FORMULATION OF INVESTIGATIONAL CYTOTOXIC DRUGS/, British Journal of Cancer, 72(1), 1995, pp. 210-218
Authors:
VANTELLINGEN O
PELS EM
HENRAR REC
SCHAAF LJ
PADBURY GE
BEIJNEN JH
NOOIJEN WJ
Citation: O. Vantellingen et al., FULLY AUTOMATED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF CARZELESIN (U-80,244) AND METABOLITES (U-76,073 ANDU-76,074) IN HUMAN PLASMA, Journal of chromatography B. Biomedical applications, 652(1), 1994, pp. 51-58
Authors:
JONKMANDEVRIES JD
TALSMA H
HENRAR REC
KETTENESVANDENBOSCH JJ
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., PHARMACEUTICAL DEVELOPMENT OF A PARENTERAL LYOPHILIZED FORMULATION OFTHE NOVEL INDOLOQUINONE ANTITUMOR AGENT E09, Cancer chemotherapy and pharmacology, 34(5), 1994, pp. 416-422
Authors:
JONKMANDEVRIES JD
DEGRAAFFTEULEN MJA
HENRAR REC
DENBOSCH JJKV
BULT A
BEIJNEN JH
Citation: Jd. Jonkmandevries et al., PHARMACEUTICAL DEVELOPMENT OF A PARENTERAL FORMULATION OF THE NOVEL ANTITUMOR AGENT CARZELESIN (U-80,244), Investigational new drugs, 12(4), 1994, pp. 303-314
Authors:
DEVRIES JD
WINKELHORST J
UNDERBERG WJM
HENRAR REC
BEIJNEN JH
Citation: Jd. Devries et al., A SYSTEMATIC STUDY ON THE CHEMICAL-STABILITY OF THE NOVEL INDOLOQUINONE ANTITUMOR AGENT EO9, International journal of pharmaceutics, 100(1-3), 1993, pp. 181-188
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