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Results: 1-25 | 26-29
Results: 1-25/29
G-PROTEIN COUPLED RECEPTORS - MODELS, MUTAGENESIS, AND DRUG DESIGN
Authors: BIKKER JA TRUMPPKALLMEYER S HUMBLET C
Citation: Ja. Bikker et al., G-PROTEIN COUPLED RECEPTORS - MODELS, MUTAGENESIS, AND DRUG DESIGN, Journal of medicinal chemistry, 41(16), 1998, pp. 2911-2927
DEVELOPMENT OF A BINDING MODEL TO PROTEIN-TYROSINE KINASES FOR SUBSTITUTED PYRIDO[2,3-D]PYRIMIDINE INHIBITORS
Authors: TRUMPPKALLMEYER S RUBIN JR HUMBLET C HAMBY JM SHOWALTER HDH
Citation: S. Trumppkallmeyer et al., DEVELOPMENT OF A BINDING MODEL TO PROTEIN-TYROSINE KINASES FOR SUBSTITUTED PYRIDO[2,3-D]PYRIMIDINE INHIBITORS, Journal of medicinal chemistry, 41(11), 1998, pp. 1752-1763
STRUCTURE-BASED DESIGN OF NOVEL, DIPEPTIDE LIGANDS TARGETING THE PP60(SRC) SH2 DOMAIN
Authors: SHAHRIPOUR A PARA KS PLUMMER MS LUNNEY EA HOLLAND DR RUBIN JR HUMBLET C FERGUS JH MARKS JS SALTIEL AR SAWYER TK
Citation: A. Shahripour et al., STRUCTURE-BASED DESIGN OF NOVEL, DIPEPTIDE LIGANDS TARGETING THE PP60(SRC) SH2 DOMAIN, Bioorganic & medicinal chemistry letters, 7(9), 1997, pp. 1107-1112
THE ROLE OF 4-PHOSPHONODIFLUOROMETHYL-PHENYLALANINE AND 4-PHOSPHONO-PHENYLALANINE IN THE SELECTIVITY AND CELLULAR UPTAKE OF SH2 DOMAIN LIGANDS
Authors: STANKOVIC CJ SURENDRAN N LUNNEY EA PLUMMER MS PARA KS SHAHRIPOUR A FERGUS JH MARKS JS HERRERA R HUBBELL SE HUMBLET C SALTIEL AR STEWART BH SAWYER TK
Citation: Cj. Stankovic et al., THE ROLE OF 4-PHOSPHONODIFLUOROMETHYL-PHENYLALANINE AND 4-PHOSPHONO-PHENYLALANINE IN THE SELECTIVITY AND CELLULAR UPTAKE OF SH2 DOMAIN LIGANDS, Bioorganic & medicinal chemistry letters, 7(14), 1997, pp. 1909-1914
STAGES IN THE DEVELOPMENT OF RADIATION-INDUCED THYMIC LYMPHOMAS IN C57 BL KA MICE - PRELEUKEMIC CELLS BECOME PROGRESSIVELY RESISTANT TO THETUMOR PREVENTING EFFECTS OF A BONE-MARROW GRAFT/
Authors: HUMBLET C GREIMERS R BONIVER J DEFRESNE MP
Citation: C. Humblet et al., STAGES IN THE DEVELOPMENT OF RADIATION-INDUCED THYMIC LYMPHOMAS IN C57 BL KA MICE - PRELEUKEMIC CELLS BECOME PROGRESSIVELY RESISTANT TO THETUMOR PREVENTING EFFECTS OF A BONE-MARROW GRAFT/, Experimental hematology, 25(2), 1997, pp. 109-113
4-HYDROXY-5,6-DIHYDROPYRONES .2. POTENT NONPEPTIDE INHIBITORS OF HIV PROTEASE
Authors: TAIT BD HAGEN S DOMAGALA J ELLSWORTH EL GAJDA C HAMILTON HW PRASAD JVNV FERGUSON D GRAHAM N HUPE D NOUHAN C TUMMINO PJ HUMBLET C LUNNEY EA PAVLOVSKY A RUBIN J GRACHECK SJ BALDWIN ET BHAT TN ERICKSON JW GULNIK SV LIU BS
Citation: Bd. Tait et al., 4-HYDROXY-5,6-DIHYDROPYRONES .2. POTENT NONPEPTIDE INHIBITORS OF HIV PROTEASE, Journal of medicinal chemistry, 40(23), 1997, pp. 3781-3792
STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF NONPEPTIDE LIGANDS THAT BIND TO THE PP60(SRC) SH2 DOMAIN
Authors: LUNNEY EA PARA KS RUBIN JR HUMBLET C FERGUS JH MARKS JS SAWYER TK
Citation: Ea. Lunney et al., STRUCTURE-BASED DESIGN OF A NOVEL SERIES OF NONPEPTIDE LIGANDS THAT BIND TO THE PP60(SRC) SH2 DOMAIN, Journal of the American Chemical Society, 119(51), 1997, pp. 12471-12476
PREVENTION OF MURINE RADIOGENIC THYMIC LYMPHOMAS BY TUMOR-NECROSIS-FACTOR OR BY MARROW GRAFTING
Authors: HUMBLET C GREIMERS R DELVENNE P DEMAN J BONIVER J DEFRESNE MP
Citation: C. Humblet et al., PREVENTION OF MURINE RADIOGENIC THYMIC LYMPHOMAS BY TUMOR-NECROSIS-FACTOR OR BY MARROW GRAFTING, Journal of the National Cancer Institute, 88(12), 1996, pp. 824-831
X-RAY STRUCTURE OF A HYDROXAMATE INHIBITOR COMPLEX OF STROMELYSIN CATALYTIC DOMAIN AND ITS COMPARISON WITH MEMBERS OF THE ZINC METALLOPROTEINASE SUPERFAMILY
Authors: DHANARAJ V YE QZ JOHNSON LL HUPE DJ ORTWINE DF DUBAR JB RUBIN JR PAVLOVSKY A HUMBLET C BLUNDELL TL
Citation: V. Dhanaraj et al., X-RAY STRUCTURE OF A HYDROXAMATE INHIBITOR COMPLEX OF STROMELYSIN CATALYTIC DOMAIN AND ITS COMPARISON WITH MEMBERS OF THE ZINC METALLOPROTEINASE SUPERFAMILY, Structure, 4(4), 1996, pp. 375-386
NOVEL PHOSPHOTYROSINE MIMETICS IN THE DESIGN OF PEPTIDE LIGANDS FOR PP60(SRC) SH2 DOMAIN
Authors: SHAHRIPOUR A PLUMMER MS LUNNEY EA PARA KS STANKOVIC CJ RUBIN JR HUMBLET C FERGUS JH MARKS JS HERRERA R HUBBELL SE SALTIEL AR SAWYER TK
Citation: A. Shahripour et al., NOVEL PHOSPHOTYROSINE MIMETICS IN THE DESIGN OF PEPTIDE LIGANDS FOR PP60(SRC) SH2 DOMAIN, Bioorganic & medicinal chemistry letters, 6(11), 1996, pp. 1209-1214
STIGMATA - AN ALGORITHM TO DETERMINE STRUCTURAL COMMONALITIES IN DIVERSE DATASETS
Authors: SHEMETULSKIS NE WEININGER D BLANKLEY CJ YANG JJ HUMBLET C
Citation: Ne. Shemetulskis et al., STIGMATA - AN ALGORITHM TO DETERMINE STRUCTURAL COMMONALITIES IN DIVERSE DATASETS, Journal of chemical information and computer sciences, 36(4), 1996, pp. 862-871
X-SITE - USE OF EMPIRICALLY DERIVED ATOMIC PACKING PREFERENCES TO IDENTIFY FAVORABLE INTERACTION REGIONS IN THE BINDING-SITES OF PROTEINS
Authors: LASKOWSKI RA THORNTON JM HUMBLET C SINGH J
Citation: Ra. Laskowski et al., X-SITE - USE OF EMPIRICALLY DERIVED ATOMIC PACKING PREFERENCES TO IDENTIFY FAVORABLE INTERACTION REGIONS IN THE BINDING-SITES OF PROTEINS, Journal of Molecular Biology, 259(1), 1996, pp. 175-201
IN-VIVO EXPRESSION OF INTERLEUKIN-1-BETA (IL-1-BETA), IL-2, IL-4, IL-6, TUMOR-NECROSIS-FACTOR-ALPHA AND INTERFERON-GAMMA IN THE FETAL MURINE THYMUS
Authors: DEMAN J VANMEURS M CLAASSEN E HUMBLET C BONIVER J DEFRESNE MP
Citation: J. Deman et al., IN-VIVO EXPRESSION OF INTERLEUKIN-1-BETA (IL-1-BETA), IL-2, IL-4, IL-6, TUMOR-NECROSIS-FACTOR-ALPHA AND INTERFERON-GAMMA IN THE FETAL MURINE THYMUS, Immunology, 89(1), 1996, pp. 152-157
BINDING OF TACRINE AND 6-CHLOROTACRINE BY ACETYLCHOLINESTERASE
Authors: WLODEK ST ANTOSIEWICZ J MCCAMMON JA STRAATSMA TP GILSON MK BRIGGS JM HUMBLET C SUSSMAN JL
Citation: St. Wlodek et al., BINDING OF TACRINE AND 6-CHLOROTACRINE BY ACETYLCHOLINESTERASE, Biopolymers, 38(1), 1996, pp. 109-117
SPONTANEOUS AND INDUCED APOPTOSIS AFTER WHOLE-BODY RADIATION EXPOSURE- EXPERIMENTAL APPROACHES - OBSERVATIONS IN RADIO-INDUCED THYMIC LYMPHOMAGENESIS
Authors: HUMBLET C DEMAN J FRANZEN R GREIMERS R BONIVER J DEFRESNE MP
Citation: C. Humblet et al., SPONTANEOUS AND INDUCED APOPTOSIS AFTER WHOLE-BODY RADIATION EXPOSURE- EXPERIMENTAL APPROACHES - OBSERVATIONS IN RADIO-INDUCED THYMIC LYMPHOMAGENESIS, Stem cells, 13, 1995, pp. 129-135
ENHANCING THE DIVERSITY OF A CORPORATE DATABASE USING CHEMICAL DATABASE CLUSTERING AND ANALYSIS
Authors: SHEMETULSKIS NE DUNBAR JB DUNBAR BW MORELAND DW HUMBLET C
Citation: Ne. Shemetulskis et al., ENHANCING THE DIVERSITY OF A CORPORATE DATABASE USING CHEMICAL DATABASE CLUSTERING AND ANALYSIS, Journal of computer-aided molecular design, 9(5), 1995, pp. 407-416
MORPHOLOGICAL-CHANGES OF THYMUS IN RETROVIRUS-INDUCED MURINE ACQUIRED-IMMUNODEFICIENCY-SYNDROME (MAIDS)
Authors: DELEVAL L DEPREZ M COLOMBI S HUMBLET C DEFRESNE MP BONIVER J MOUTSCHEN M
Citation: L. Deleval et al., MORPHOLOGICAL-CHANGES OF THYMUS IN RETROVIRUS-INDUCED MURINE ACQUIRED-IMMUNODEFICIENCY-SYNDROME (MAIDS), Pathology research and practice, 191(6), 1995, pp. 506-512
2 CLASSES OF STRUCTURALLY DIFFERENT ANTAGONISTS DISPLAY SIMILAR SPECIES PREFERENCE FOR THE HUMAN TACHYKININ NEUROKININ(3) RECEPTOR
Authors: CHUNG FZ WU LH TIAN Y VARTANIAN MA LEE H BIKKER J HUMBLET C PRITCHARD MC RAPHY J SUMANCHAUHAN N HORWELL DC LALWANI ND OXENDER DL
Citation: Fz. Chung et al., 2 CLASSES OF STRUCTURALLY DIFFERENT ANTAGONISTS DISPLAY SIMILAR SPECIES PREFERENCE FOR THE HUMAN TACHYKININ NEUROKININ(3) RECEPTOR, Molecular pharmacology, 48(4), 1995, pp. 711-716
DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS
Authors: PLUMMER MS SHAHRIPOUR A KALTENBRONN JS LUNNEY EA STEINBAUGH BA HAMBY JM HAMILTON HW SAWYER TK HUMBLET C DOHERTY AM TAYLOR MD HINGORANI G BATLEY BL RAPUNDALO ST
Citation: Ms. Plummer et al., DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS, Journal of medicinal chemistry, 38(15), 1995, pp. 2893-2905
STRUCTURAL STUDIES ON THE PH DOMAINS OF DBL, SOS1, IRS-1, AND BETA-ARK1 AND THEIR DIFFERENTIAL BINDING TO G(BETA-GAMMA) SUBUNITS
Authors: MAHADEVAN D THANKI N SINGH J MCPHIE P ZANGRILLI D WANG LM GUERRERO C LEVINE H HUMBLET C SALDANHA J GUTKIND JS NAJMABADIHASKE T
Citation: D. Mahadevan et al., STRUCTURAL STUDIES ON THE PH DOMAINS OF DBL, SOS1, IRS-1, AND BETA-ARK1 AND THEIR DIFFERENTIAL BINDING TO G(BETA-GAMMA) SUBUNITS, Biochemistry, 34(28), 1995, pp. 9111-9117
SNAIL AND SPIDER TOXINS SHARE A SIMILAR TERTIARY STRUCTURE AND CYSTINE MOTIF
Authors: NARASIMHAN L SINGH J HUMBLET C GURUPRASAD K BLUNDELL T
Citation: L. Narasimhan et al., SNAIL AND SPIDER TOXINS SHARE A SIMILAR TERTIARY STRUCTURE AND CYSTINE MOTIF, Nature structural biology, 1(12), 1994, pp. 850-852
PRESENTATION AND INTERCELLULAR TRANSFER OF SELF ANTIGEN WITHIN THE THYMIC MICROENVIRONMENT - EXPRESSION OF THE E-ALPHA PEPTIDE I-AB COMPLEXBY ISOLATED THYMIC STROMAL CELLS
Authors: HUMBLET C RUDENSKY AY KYEWSKI B
Citation: C. Humblet et al., PRESENTATION AND INTERCELLULAR TRANSFER OF SELF ANTIGEN WITHIN THE THYMIC MICROENVIRONMENT - EXPRESSION OF THE E-ALPHA PEPTIDE I-AB COMPLEXBY ISOLATED THYMIC STROMAL CELLS, International immunology, 6(12), 1994, pp. 1949-1958
ANALYSIS BY IN-SITU HYBRIDIZATION OF CYTOKINE MESSENGER-RNA EXPRESSION IN THE MURINE DEVELOPING THYMUS
Authors: DEMAN J HUMBLET C MARTIN MT BONIVER J DEFRESNE MP
Citation: J. Deman et al., ANALYSIS BY IN-SITU HYBRIDIZATION OF CYTOKINE MESSENGER-RNA EXPRESSION IN THE MURINE DEVELOPING THYMUS, International immunology, 6(10), 1994, pp. 1613-1619
THYMUS INVOLVEMENT IN MURINE ACQUIRED IMMUNODEFICIENCY (MAIDS)
Authors: COLOMBI S DEPREZ M DELEVAL L HUMBLET C GREIMERS R DEFRESNE MP BONIVER J MOUTSCHEN M
Citation: S. Colombi et al., THYMUS INVOLVEMENT IN MURINE ACQUIRED IMMUNODEFICIENCY (MAIDS), Thymus, 23(1), 1994, pp. 27-37
A NOVEL NONPEPTIDE HIV-1 PROTEASE INHIBITOR - ELUCIDATION OF THE BINDING MODE AND ITS APPLICATION IN THE DESIGN OF RELATED ANALOGS
Authors: LUNNEY EA HAGEN SE DOMAGALA JM HUMBLET C KOSINSKI J TAIT BD WARMUS JS WILSON M FERGUSON D HUPE D TUMMINO PJ BALDWIN ET BHAT TN LIU BS ERICKSON JW
Citation: Ea. Lunney et al., A NOVEL NONPEPTIDE HIV-1 PROTEASE INHIBITOR - ELUCIDATION OF THE BINDING MODE AND ITS APPLICATION IN THE DESIGN OF RELATED ANALOGS, Journal of medicinal chemistry, 37(17), 1994, pp. 2664-2677
Risultati: 1-25 | 26-29