Authors:
Marriott, JH
Aherne, GW
Hardcastle, A
Jarman, M
Citation: Jh. Marriott et al., Synthesis of certain 2 '-deoxyuridine derivatives containing substituted phenoxy groups attached to C-5 '; Evaluation as potential dUTP analogues, NUCLEOS NUC, 20(9), 2001, pp. 1691-1704
Authors:
Aherne, GW
Hardcastle, A
Ward, E
Dobinson, D
Crompton, T
Valenti, M
Brunton, L
Jackman, AL
Citation: Gw. Aherne et al., Pharmacokinetic/pharmacodynamic study of ZD9331, a nonpolyglutamatable inhibitor of thymidylate synthase, in a murine model following two curative administration schedules, CLIN CANC R, 7(9), 2001, pp. 2923-2930
Authors:
Turlais, F
Hardcastle, A
Rowlands, M
Newbatt, Y
Bannister, A
Kouzarides, T
Workman, P
Aherne, GW
Citation: F. Turlais et al., High-throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (FlashPlate), ANALYT BIOC, 298(1), 2001, pp. 62-68
Authors:
Pusch, CM
Zeitz, C
Brandau, O
Pesch, K
Achatz, H
Feil, S
Scharfe, C
Maurer, J
Jacobi, FK
Pinckers, A
Andreasson, S
Hardcastle, A
Wissinger, B
Berger, W
Meindl, A
Citation: Cm. Pusch et al., The complete form of X-linked congenital stationary night blindness is caused by mutations in a gene encoding a leucine-rich repeat protein, NAT GENET, 26(3), 2000, pp. 324-327
Authors:
Webley, SD
Hardcastle, A
Ladner, RD
Jackman, AL
Aherne, GW
Citation: Sd. Webley et al., Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331, BR J CANC, 83(6), 2000, pp. 792-799
Authors:
Barnes, MJ
Estlin, EJ
Taylor, GA
Aherne, GW
Hardcastle, A
McGuire, JJ
Calvete, JA
Lunec, J
Pearson, ADJ
Newell, DR
Citation: Mj. Barnes et al., Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines, CLIN CANC R, 5(9), 1999, pp. 2548-2558