AAAAAA

   
Results: 1-25 | 26-28
Results: 1-25/28
A beta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice
Authors: Tomidokoro, Y Ishiguro, K Harigaya, Y Matsubara, E Ikeda, M Park, JM Yasutake, K Kawarabayashi, T Okamoto, K Shoji, M
Citation: Y. Tomidokoro et al., A beta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice, NEUROSCI L, 299(3), 2001, pp. 169-172
The levels of cerebrospinal fluid A beta 40 and A beta 42(43) are regulated age-dependently
Authors: Shoji, M Kanai, M Matsubara, E Tomidokoro, Y Shizuka, M Ikeda, Y Ikeda, M Harigaya, Y Okamoto, K Hirai, S
Citation: M. Shoji et al., The levels of cerebrospinal fluid A beta 40 and A beta 42(43) are regulated age-dependently, NEUROBIOL A, 22(2), 2001, pp. 209-215
Novel synthesis of tetrahydro-2(1H)-quinolones using Diels-Alder reactionsof 1-arylsulfonyl-2(1H)-pyridones having an electron-withdrawing group
Authors: Fujita, R Watanabe, K Ikeura, W Ohtake, Y Hongo, H Harigaya, Y Matsuzaki, H
Citation: R. Fujita et al., Novel synthesis of tetrahydro-2(1H)-quinolones using Diels-Alder reactionsof 1-arylsulfonyl-2(1H)-pyridones having an electron-withdrawing group, TETRAHEDRON, 57(42), 2001, pp. 8841-8850
First total synthesis of Mer-N5075A and a diastereomeric mixture of alpha and beta-MAPI, new HIV-I protease inhibitors from a species of Streptomyces
Authors: Konda, Y Takahashi, Y Arima, S Sato, N Takeda, K Dobashi, K Baba, M Harigaya, Y
Citation: Y. Konda et al., First total synthesis of Mer-N5075A and a diastereomeric mixture of alpha and beta-MAPI, new HIV-I protease inhibitors from a species of Streptomyces, TETRAHEDRON, 57(20), 2001, pp. 4311-4321
Brain A beta amyloidosis in APPsw mice induces accumulation of presenilin-I and tau
Authors: Tomidokoro, Y Harigaya, Y Matsubara, E Ikeda, M Kawarabayashi, T Shirao, T Ishiguro, K Okamoto, K Younkin, SG Shoji, M
Citation: Y. Tomidokoro et al., Brain A beta amyloidosis in APPsw mice induces accumulation of presenilin-I and tau, J PATHOLOGY, 194(4), 2001, pp. 500-506
Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ataxia
Authors: Takenoshita, H Shizuka-Ikeda, M Mitoma, H Song, SY Harigaya, Y Igeta, Y Yaguchi, M Ishida, K Shoji, M Tanaka, M Mizusawa, H Okamoto, K
Citation: H. Takenoshita et al., Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ataxia, J NE NE PSY, 70(3), 2001, pp. 386-389
Convergent synthesis of arisugacin skeletons and their acetylcholinesterase inhibitory activity
Authors: Handa, M Sunazuka, T Nagai, K Kimura, R Shirahata, T Tian, ZM Otoguro, K Harigaya, Y Omura, S
Citation: M. Handa et al., Convergent synthesis of arisugacin skeletons and their acetylcholinesterase inhibitory activity, J ANTIBIOT, 54(4), 2001, pp. 382-385
Determination of absolute stereochemistries of arisugacin F and territrem B, novel acetylcholinesterase inhibitors
Authors: Handa, M Sunazuka, T Nagai, R Kimura, R Otoguro, K Harigaya, Y Omura, S
Citation: M. Handa et al., Determination of absolute stereochemistries of arisugacin F and territrem B, novel acetylcholinesterase inhibitors, J ANTIBIOT, 54(4), 2001, pp. 386-391
Synthesis of phenanthridones using Diels-Alder reactions of 4-substituted 2(1H)-quinolones acting as dienophiles
Authors: Fujita, R Watanabe, K Yoshisuji, T Matsuzaki, H Harigaya, Y Hongo, H
Citation: R. Fujita et al., Synthesis of phenanthridones using Diels-Alder reactions of 4-substituted 2(1H)-quinolones acting as dienophiles, CHEM PHARM, 49(4), 2001, pp. 407-412
Synthesis of cis- and trans-5,8-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone
Authors: Arima, S Konda, YY Takeda, K Takayanagi, H Harigaya, Y
Citation: S. Arima et al., Synthesis of cis- and trans-5,8-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone, CHEM PHARM, 49(10), 2001, pp. 1340-1342
Distribution of amyloid beta protein precursor in the Alzheimer's disease brain
Authors: Shoji, M Kawarabayashi, T Matsubara, E Ikeda, M Ishiguro, K Harigaya, Y Okamoto, K
Citation: M. Shoji et al., Distribution of amyloid beta protein precursor in the Alzheimer's disease brain, PSY CLIN N, 54(1), 2000, pp. 45-54
Synthetic conversion of ACAT inhibitor to acetylcholinesterase inhibitor
Authors: Obata, R Sunazuka, T Otoguro, K Tomoda, H Harigaya, Y Omura, S
Citation: R. Obata et al., Synthetic conversion of ACAT inhibitor to acetylcholinesterase inhibitor, BIOORG MED, 10(12), 2000, pp. 1315-1316
Total syntheses of kurasoins A and B, novel protein farnesyltransferase inhibitors, and absolute structures of kurasoins A and B
Authors: Hirose, T Sunazuka, T Tian, ZM Handa, M Uchida, R Shiomi, K Harigaya, Y Omura, S
Citation: T. Hirose et al., Total syntheses of kurasoins A and B, novel protein farnesyltransferase inhibitors, and absolute structures of kurasoins A and B, HETEROCYCLE, 53(4), 2000, pp. 777-784
Taps to Alzheimer's patients: A continuous Japanese study of cerebrospinalfluid biomarkers
Authors: Shoji, M Kanai, M Matsubara, E Ikeda, M Harigaya, Y Okamoto, K Hirai, S
Citation: M. Shoji et al., Taps to Alzheimer's patients: A continuous Japanese study of cerebrospinalfluid biomarkers, ANN NEUROL, 48(3), 2000, pp. 402-402
Impaired neurotransmitter systems by A beta amyloidosis in APPsw transgenic mice overexpressing amyloid beta protein precursor
Authors: Tomidokoro, Y Harigaya, Y Matsubara, E Ikeda, M Kawarabayashi, T Okamoto, K Shoji, M
Citation: Y. Tomidokoro et al., Impaired neurotransmitter systems by A beta amyloidosis in APPsw transgenic mice overexpressing amyloid beta protein precursor, NEUROSCI L, 292(3), 2000, pp. 155-158
Structure and stereochemistry of nardostachysin, a new terpenoid ester constituent of the rhizomes of Naradostachys jatamansi
Authors: Chatterjee, A Basak, B Saha, M Dutta, U Mukhopadhyay, C Banerji, J Konda, Y Harigaya, Y
Citation: A. Chatterjee et al., Structure and stereochemistry of nardostachysin, a new terpenoid ester constituent of the rhizomes of Naradostachys jatamansi, J NAT PROD, 63(11), 2000, pp. 1531-1533
Neat formic acid: An excellent N-formylating agent for carbazoles, 3-alkylindoles, diphenylamine and moderately weak nucleophilic anilines
Authors: Chakrabarty, M Khasnobis, S Harigaya, Y Konda, Y
Citation: M. Chakrabarty et al., Neat formic acid: An excellent N-formylating agent for carbazoles, 3-alkylindoles, diphenylamine and moderately weak nucleophilic anilines, SYN COMMUN, 30(2), 2000, pp. 187-200
Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice
Authors: Shoji, M Kawarabayashi, T Sato, M Sasaki, A Saido, TC Matsubara, E Tomidokoro, Y Kanai, M Shizuka, M Ishiguro, K Ikeda, M Harigaya, Y Okamoto, K Hirai, S
Citation: M. Shoji et al., Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice, J PATHOLOGY, 191(1), 2000, pp. 93-101
Accumulation of NACP/alpha-synuclein in Lewy body disease and multiple system atrophy
Authors: Shoji, M Harigaya, Y Sasaki, A Ueda, K Ishiguro, K Matsubara, E Watanabe, M Ikeda, M Kanai, M Tomidokoro, Y Shizuka, M Amari, M Kosaka, K Nakazato, Y Okamoto, K Hirai, S
Citation: M. Shoji et al., Accumulation of NACP/alpha-synuclein in Lewy body disease and multiple system atrophy, J NE NE PSY, 68(5), 2000, pp. 605-608
Structure-activity relationships study of pyripyropenes: Reversal of cancer cell multidrug resistance
Authors: Obata, R Sunazuka, T Harigaya, Y Hayashi, M Rho, MC Tomoda, H Omura, S
Citation: R. Obata et al., Structure-activity relationships study of pyripyropenes: Reversal of cancer cell multidrug resistance, J ANTIBIOT, 53(4), 2000, pp. 422-425
Synthesis and antiangiogenic activity of staurosporine derivatives
Authors: Li, ZR Sunazuka, T Yamada, R Kato, Y Enomoto, A Hayashi, M Harigaya, Y Omura, S
Citation: Zr. Li et al., Synthesis and antiangiogenic activity of staurosporine derivatives, J ANTIBIOT, 53(4), 2000, pp. 426-429
Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain
Authors: Harigaya, Y Saido, TC Eckman, CB Prada, CM Shoji, M Younkin, SG
Citation: Y. Harigaya et al., Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain, BIOC BIOP R, 276(2), 2000, pp. 422-427
Lipoprotein-free amyloidogenic peptides in plasma are elevated in patientswith sporadic Alzheimer's disease and Down's syndrome
Authors: Matsubara, E Ghiso, J Frangione, B Amari, M Tomidokoro, Y Ikeda, Y Harigaya, Y Okamoto, K Shoji, M
Citation: E. Matsubara et al., Lipoprotein-free amyloidogenic peptides in plasma are elevated in patientswith sporadic Alzheimer's disease and Down's syndrome, ANN NEUROL, 45(4), 1999, pp. 537-541
Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease
Authors: Kanai, M Shizuka, M Urakami, K Matsubara, E Harigaya, Y Okamoto, K Shoji, M
Citation: M. Kanai et al., Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease, NEUROSCI L, 267(1), 1999, pp. 65-68
Macrocyclization by TTN oxidation for the synthesis of Chloropeptin left-hand segment
Authors: Kai, T Kajimoto, N Konda, Y Harigaya, Y Takayanagi, H
Citation: T. Kai et al., Macrocyclization by TTN oxidation for the synthesis of Chloropeptin left-hand segment, TETRAHEDR L, 40(34), 1999, pp. 6289-6292
Risultati: 1-25 | 26-28