Authors:
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White, A
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Medina, N
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Citation: A. Pasternak et al., The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity, PROTEIN SCI, 10(7), 2001, pp. 1331-1342
Authors:
Sazonova, IY
Houng, AK
Chowdhry, SA
Robinson, BR
Hedstrom, L
Reed, GL
Citation: Iy. Sazonova et al., The mechanism of a bacterial plasminogen activator intermediate between streptokinase and staphylokinase, J BIOL CHEM, 276(16), 2001, pp. 12609-12613
Authors:
McLean, JE
Neidhardt, EA
Grossman, TH
Hedstrom, L
Citation: Je. Mclean et al., Multiple inhibitor analysis of the brequinar and leflunomide binding siteson human dihydroorotate dehydrogenase, BIOCHEM, 40(7), 2001, pp. 2194-2200
Authors:
Huang, XY
Knoell, CT
Frey, G
Hazegh-Azam, M
Tashijian, AH
Hedstrom, L
Abeles, RH
Timasheff, SN
Citation: Xy. Huang et al., Modulation of recombinant human prostate-specific antigen: Activation by Hofmeister salts and inhibition by azapeptides, BIOCHEM, 40(39), 2001, pp. 11734-11741
Citation: Sg. Wang et al., Zymogen activation in the streptokinase-plasminogen complex - Ile1 is required for the formation of a functional active site, EUR J BIOCH, 267(13), 2000, pp. 3994-4001
Citation: Ja. Digits et L. Hedstrom, Drug selectivity is determined by coupling across the NAD(+) site of IMP dehydrogenase, BIOCHEM, 39(7), 2000, pp. 1771-1777
Citation: Y. Dai et al., Inactivation of cysteine proteases by (acyloxy)methyl ketones using S '-P ' interactions, BIOCHEM, 39(21), 2000, pp. 6498-6502
Authors:
McMillan, FM
Cahoon, M
White, A
Hedstrom, L
Petsko, GA
Ringe, D
Citation: Fm. Mcmillan et al., Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5 '-monophosphate dehydrogenase: Evidence of a substrate-induced hinged-lid motion by loop 6, BIOCHEM, 39(15), 2000, pp. 4533-4542
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Citation: A. Pasternak et al., Comparison of anionic and cationic trypsinogens: The anionic activation domain is more flexible in solution and differs in its mode of BPTI binding in the crystal structure, PROTEIN SCI, 8(1), 1999, pp. 253-258
Authors:
Reed, GL
Houng, AK
Liu, L
Parhami-Seren, B
Matsueda, LH
Wang, SG
Hedstrom, L
Citation: Gl. Reed et al., A catalytic switch and the conversion of streptokinase to a fibrin-targeted plasminogen activator, P NAS US, 96(16), 1999, pp. 8879-8883
Citation: Ja. Digits et L. Hedstrom, Kinetic mechanism of Tritrichomonas foetus inosine 5 '-monophosphate dehydrogenase, BIOCHEM, 38(8), 1999, pp. 2295-2306
Citation: Ja. Digits et L. Hedstrom, Species-specific inhibition of inosine 5 '-monophosphate dehydrogenase by mycophenolic acid, BIOCHEM, 38(46), 1999, pp. 15388-15397
Citation: Sg. Wang et al., Deletion of Ile1 changes the mechanism of streptokinase: Evidence for the molecular sexuality hypothesis, BIOCHEM, 38(16), 1999, pp. 5232-5240