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Results: 1-25 | 26-44
Results: 1-25/44
Analysis of protein kinase B/Akt
Authors: Hill, MM Hemmings, BA
Citation: Mm. Hill et Ba. Hemmings, Analysis of protein kinase B/Akt, METH ENZYM, 345, 2002, pp. 448-463
The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappa B activation
Authors: Heussler, VT Kuenzi, P Fraga, F Schwab, RA Hemmings, BA Dobbelaere, DAE
Citation: Vt. Heussler et al., The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappa B activation, CELL MICROB, 3(8), 2001, pp. 537-550
Ten years of protein kinase B signalling: a hard Akt to follow
Authors: Brazil, DP Hemmings, BA
Citation: Dp. Brazil et Ba. Hemmings, Ten years of protein kinase B signalling: a hard Akt to follow, TRENDS BIOC, 26(11), 2001, pp. 657-664
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
Authors: Brunet, A Park, J Tran, H Hu, LS Hemmings, BA Greenberg, ME
Citation: A. Brunet et al., Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a), MOL CELL B, 21(3), 2001, pp. 952-965
Active-site mutations impairing the catalytic function of the catalytic subunit of human protein phosphatase 2A permit baculovirus-mediated overexpression in insect cells
Authors: Myles, T Schmidt, K Evans, DRH Cron, P Hemmings, BA
Citation: T. Myles et al., Active-site mutations impairing the catalytic function of the catalytic subunit of human protein phosphatase 2A permit baculovirus-mediated overexpression in insect cells, BIOCHEM J, 357, 2001, pp. 225-232
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
Authors: Maira, SM Galetic, I Brazil, DP Kaech, S Ingley, E Thelen, M Hemmings, BA
Citation: Sm. Maira et al., Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane, SCIENCE, 294(5541), 2001, pp. 374-380
Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice
Authors: Kins, S Crameri, A Evans, DRH Hemmings, BA Nitsch, RM Gotz, J
Citation: S. Kins et al., Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice, J BIOL CHEM, 276(41), 2001, pp. 38193-38200
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity
Authors: Park, J Hill, MM Hess, D Brazil, DP Hofsteenge, J Hemmings, BA
Citation: J. Park et al., Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity, J BIOL CHEM, 276(40), 2001, pp. 37459-37471
Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain
Authors: Brodbeck, D Hill, MM Hemmings, BA
Citation: D. Brodbeck et al., Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain, J BIOL CHEM, 276(31), 2001, pp. 29550-29558
Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase
Authors: Hill, MM Andjelkovic, M Brazil, DP Ferrari, S Fabbro, D Hemmings, BA
Citation: Mm. Hill et al., Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase, J BIOL CHEM, 276(28), 2001, pp. 25643-25646
Protein kinase B beta/Akt2 plays a specific role in muscle differentiation
Authors: Vandromme, M Rochat, A Meier, R Carnac, G Besser, D Hemmings, BA Fernandez, A Lamb, NJC
Citation: M. Vandromme et al., Protein kinase B beta/Akt2 plays a specific role in muscle differentiation, J BIOL CHEM, 276(11), 2001, pp. 8173-8179
In vitro and in vivo studies of a naturally occurring variant of the humanp85 alpha regulatory subunit of the phosphoinositide 3-kinase - Inhibitionof protein kinase B and relationships with type 2 diabetes, insulin secretion, glucose disappearance constant, and insulin sensitivity
Authors: Hansen, L Zethelius, B Berglund, L Reneland, R Hansen, T Berne, C Lithell, B Hemmings, BA Pedersen, O
Citation: L. Hansen et al., In vitro and in vivo studies of a naturally occurring variant of the humanp85 alpha regulatory subunit of the phosphoinositide 3-kinase - Inhibitionof protein kinase B and relationships with type 2 diabetes, insulin secretion, glucose disappearance constant, and insulin sensitivity, DIABETES, 50(3), 2001, pp. 690-693
Cell polarity: Scaffold proteins par excellence
Authors: Brazil, DP Hemmings, BA
Citation: Dp. Brazil et Ba. Hemmings, Cell polarity: Scaffold proteins par excellence, CURR BIOL, 10(16), 2000, pp. R592-R594
Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
Authors: Filippa, N Sable, CL Hemmings, BA Van Obberghen, E
Citation: N. Filippa et al., Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation, MOL CELL B, 20(15), 2000, pp. 5712-5721
The crystal structure of human eukaryotic release factor eRF1 - Mechanism of stop codon recognition and peptidyl-tRNA hydrolysis
Authors: Song, HW Mugnier, P Das, AK Webb, HM Evans, DR Tuite, MF Hemmings, BA Barford, D
Citation: Hw. Song et al., The crystal structure of human eukaryotic release factor eRF1 - Mechanism of stop codon recognition and peptidyl-tRNA hydrolysis, CELL, 100(3), 2000, pp. 311-321
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
Authors: Clemens, JC Worby, CA Simonson-Leff, N Muda, M Maehama, T Hemmings, BA Dixon, JE
Citation: Jc. Clemens et al., Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways, P NAS US, 97(12), 2000, pp. 6499-6503
Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae
Authors: Evans, DRH Hemmings, BA
Citation: Drh. Evans et Ba. Hemmings, Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae, MOL G GENET, 264(4), 2000, pp. 425-432
p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1)
Authors: King, CC Gardiner, EMM Zenke, FT Bohl, BP Newton, AC Hemmings, BA Bokoch, GM
Citation: Cc. King et al., p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1), J BIOL CHEM, 275(52), 2000, pp. 41201-41209
Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway
Authors: Bell, LM Leong, MLL Kim, B Wang, E Park, J Hemmings, BA Firestone, GL
Citation: Lm. Bell et al., Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway, J BIOL CHEM, 275(33), 2000, pp. 25262-25272
Raf-1-associated protein phosphatase 2A as a positive regulator of kinase activation
Authors: Abraham, D Podar, K Pacher, M Kubicek, M Welzel, N Hemmings, BA Dilworth, SM Mischak, H Kolch, W Baccarini, M
Citation: D. Abraham et al., Raf-1-associated protein phosphatase 2A as a positive regulator of kinase activation, J BIOL CHEM, 275(29), 2000, pp. 22300-22304
Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1
Authors: King, CC Zenke, FT Dawson, PE Dutil, EM Newton, AC Hemmings, BA Bokoch, GM
Citation: Cc. King et al., Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1, J BIOL CHEM, 275(24), 2000, pp. 18108-18113
Important role for phylogenetically invariant PP2Ac alpha active site and C-terminal residues revealed by mutational analysis in Saccharomyces cerevisiae
Authors: Evans, DRH Hemmings, BA
Citation: Drh. Evans et Ba. Hemmings, Important role for phylogenetically invariant PP2Ac alpha active site and C-terminal residues revealed by mutational analysis in Saccharomyces cerevisiae, GENETICS, 156(1), 2000, pp. 21-29
PKB/Akt interacts with inosine-5 ' monophosphate dehydrogenase through itspleckstrin homology domain
Authors: Ingley, E Hemmings, BA
Citation: E. Ingley et Ba. Hemmings, PKB/Akt interacts with inosine-5 ' monophosphate dehydrogenase through itspleckstrin homology domain, FEBS LETTER, 478(3), 2000, pp. 253-259
Biochemical characterization of recombinant subunits of type 2A protein phosphatase overexpressed in Pichia pastoris
Authors: Swiatek, W Sugajska, E Lankiewicz, L Hemmings, BA Zolnierowicz, S
Citation: W. Swiatek et al., Biochemical characterization of recombinant subunits of type 2A protein phosphatase overexpressed in Pichia pastoris, EUR J BIOCH, 267(16), 2000, pp. 5209-5216
Regulation of protein kinase B
Authors: Meier, R Hemmings, BA
Citation: R. Meier et Ba. Hemmings, Regulation of protein kinase B, J RECEPT SI, 19(1-4), 1999, pp. 121-128
Risultati: 1-25 | 26-44