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Results: 1-11 |
Results: 11
Methyl analogues of the experimental Alzheimer drug phenserine: Synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action
Authors: Yu, QS Holloway, HW Flippen-Anderson, JL Hoffman, B Brossi, A Greig, NH
Citation: Qs. Yu et al., Methyl analogues of the experimental Alzheimer drug phenserine: Synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action, J MED CHEM, 44(24), 2001, pp. 4062-4071
Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent
Authors: Doyle, ME Greig, NH Holloway, HW Betkey, JA Bernier, M Egan, JM
Citation: Me. Doyle et al., Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent, ENDOCRINOL, 142(10), 2001, pp. 4462-4468
(-)-(3aS)-eseroline carbamate (II), a potent cholinesterase inhibitor and close analogue of physostigmine: Reanalysis
Authors: Yu, QS Greig, NH Holloway, HW Flippen-Anderson, JL Brossi, A
Citation: Qs. Yu et al., (-)-(3aS)-eseroline carbamate (II), a potent cholinesterase inhibitor and close analogue of physostigmine: Reanalysis, MED CHEM RE, 10(3), 2000, pp. 186-199
Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans
Authors: Furey, ML Pietrini, P Alexander, GE Mentis, MJ Szczepanik, J Shetty, U Greig, NH Holloway, HW Schapiro, MB Freo, U
Citation: Ml. Furey et al., Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans, PHARM BIO B, 66(3), 2000, pp. 475-481
A practical conversion of natural physostigmine into the potent butyrylcholinesterase inhibitor N-1,N-8-bisnorcymserine
Authors: Zhu, XX Greig, NH Holloway, HW Whittaker, NF Brossi, A Yu, QS
Citation: Xx. Zhu et al., A practical conversion of natural physostigmine into the potent butyrylcholinesterase inhibitor N-1,N-8-bisnorcymserine, TETRAHEDR L, 41(25), 2000, pp. 4861-4864
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
Authors: Szayna, M Doyle, ME Betkey, JA Holloway, HW Spencer, RGS Greig, NH Egan, JM
Citation: M. Szayna et al., Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats, ENDOCRINOL, 141(6), 2000, pp. 1936-1941
The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics
Authors: Greig, NH De Micheli, E Holloway, HW Yu, QS Utsuki, T Perry, TA Brossi, A Ingram, DK Deutsch, J Lahiri, DK Soncrant, TT
Citation: Nh. Greig et al., The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics, ACT NEUR SC, 102, 2000, pp. 74-84
Syntheses and biological evaluation of ring-C opened analogues of the cholinesterase inhibitors physostigmine, phenserine and cymserine
Authors: Pei, XF Yu, QS Holloway, HW Brossi, A Greig, NH
Citation: Xf. Pei et al., Syntheses and biological evaluation of ring-C opened analogues of the cholinesterase inhibitors physostigmine, phenserine and cymserine, MED CHEM RE, 9(1), 1999, pp. 50-60
4 '-hydroxyphenylcarbamates of (3aS)-eseroline and (3aS)-N(1)-noreseroline: Potential metabolites of the Alzheimer's anticholinesterase drug phenserine
Authors: Yu, QS Greig, NH Holloway, HW Brossi, A
Citation: Qs. Yu et al., 4 '-hydroxyphenylcarbamates of (3aS)-eseroline and (3aS)-N(1)-noreseroline: Potential metabolites of the Alzheimer's anticholinesterase drug phenserine, HETEROCYCLE, 50(1), 1999, pp. 95-102
Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease
Authors: Yu, QS Holloway, HW Utsuki, T Brossi, A Greig, NH
Citation: Qs. Yu et al., Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease, J MED CHEM, 42(10), 1999, pp. 1855-1861
Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations
Authors: Greig, NH Holloway, HW De Ore, KA Jani, D Wang, Y Zhou, J Garant, MJ Egan, JM
Citation: Nh. Greig et al., Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations, DIABETOLOG, 42(1), 1999, pp. 45-50
Risultati: 1-11 |