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Results: 1-25 | 26-50 | 51-58
Results: 1-25/58
Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Kii peninsula of Japan: Clinical and neuropathological study and tau analysis
Authors: Kuzuhara, S Kokubo, Y Sasaki, R Narita, Y Yabana, T Hasegawa, M Iwatsubo, T
Citation: S. Kuzuhara et al., Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Kii peninsula of Japan: Clinical and neuropathological study and tau analysis, ANN NEUROL, 49(4), 2001, pp. 501-511
Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques
Authors: Mann, DMA Takeuchi, A Sato, S Cairns, NJ Lantos, PL Rossor, MN Haltia, M Kalimo, H Iwatsubo, T
Citation: Dma. Mann et al., Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques, NEUROP AP N, 27(3), 2001, pp. 189-196
Tau accumulation in a patient with pallidonigroluysian atrophy
Authors: Mori, H Motoi, Y Kobayashi, T Hasegawa, M Yamamura, A Iwatsubo, T Mizuno, Y
Citation: H. Mori et al., Tau accumulation in a patient with pallidonigroluysian atrophy, NEUROSCI L, 309(2), 2001, pp. 89-92
Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: relationship to age and apolipoprotein E genotype
Authors: Mann, DMA McDonagh, AM Pickering-Brown, SM Kowa, H Iwatsubo, T
Citation: Dma. Mann et al., Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: relationship to age and apolipoprotein E genotype, NEUROSCI L, 304(3), 2001, pp. 161-164
In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans
Authors: Hirota, N Ito, K Iwatsubo, T Green, CE Tyson, CA Shimada, N Suzuki, H Sugiyama, Y
Citation: N. Hirota et al., In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans, BIOPHARM DR, 22(2), 2001, pp. 53-71
Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease
Authors: Lambert, JC Mann, D Goumidi, L Harris, J Amouyel, P Iwatsubo, T Lendon, C Chartier-Harlin, MC
Citation: Jc. Lambert et al., Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease, LANCET, 357(9256), 2001, pp. 608-609
Variant Alzheimer disease with spastic paraparesis: Neuropathological phenotype
Authors: Verkkoniemi, A Kalimo, H Paetau, A Somer, M Iwatsubo, T Hardy, J Haltia, M
Citation: A. Verkkoniemi et al., Variant Alzheimer disease with spastic paraparesis: Neuropathological phenotype, J NE EXP NE, 60(5), 2001, pp. 483-492
The-48 C/T polymorphism in the presenilin 1 promoter is associated with anincreased risk of developing Alzheimer's disease and an increased A beta load in brain
Authors: Lambert, JC Mann, DMA Harris, JM Chartier-Harlin, MC Cumming, A Coates, J Lemmon, H StClair, D Iwatsubo, T Lendon, C
Citation: Jc. Lambert et al., The-48 C/T polymorphism in the presenilin 1 promoter is associated with anincreased risk of developing Alzheimer's disease and an increased A beta load in brain, J MED GENET, 38(6), 2001, pp. 353-355
Prediction of the melting point of n-alkanes using the molecular dynamics method
Authors: Tsuchiya, Y Hasegawa, H Iwatsubo, T
Citation: Y. Tsuchiya et al., Prediction of the melting point of n-alkanes using the molecular dynamics method, J CHEM PHYS, 114(5), 2001, pp. 2484-2488
Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity
Authors: Ikegaya, Y Kim, JA Baba, M Iwatsubo, T Nishiyama, N Matsuki, N
Citation: Y. Ikegaya et al., Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity, J CELL SCI, 114(22), 2001, pp. 4083-4093
The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins
Authors: Tomita, T Watabiki, T Takikawa, R Morohashi, Y Takasugi, N Kopan, R De Strooper, B Iwatsubo, T
Citation: T. Tomita et al., The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins, J BIOL CHEM, 276(35), 2001, pp. 33273-33281
Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the A beta 42-promoting effects of Alzheimer mutant presenilin 2
Authors: Iwata, H Tomita, T Maruyama, K Iwatsubo, T
Citation: H. Iwata et al., Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the A beta 42-promoting effects of Alzheimer mutant presenilin 2, J BIOL CHEM, 276(24), 2001, pp. 21678-21685
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
Authors: Shirotani, K Tsubuki, S Iwata, N Takaki, Y Harigaya, W Maruyama, K Kiryu-Seo, S Kiyama, H Iwata, H Tomita, T Iwatsubo, T Saido, TC
Citation: K. Shirotani et al., Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases, J BIOL CHEM, 276(24), 2001, pp. 21895-21901
Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains
Authors: Taniguchi, S Fujita, Y Hayashi, S Kakita, A Takahashi, H Murayama, S Saido, TC Hisanaga, S Iwatsubo, T Hasegawa, M
Citation: S. Taniguchi et al., Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains, FEBS LETTER, 489(1), 2001, pp. 46-50
Molecular cloning and expression of the novel splice variants of K+ channel-interacting protein 2
Authors: Ohya, S Morohashi, Y Muraki, K Tomita, T Watanabe, M Iwatsubo, T Imaizumi, Y
Citation: S. Ohya et al., Molecular cloning and expression of the novel splice variants of K+ channel-interacting protein 2, BIOC BIOP R, 282(1), 2001, pp. 96-102
Localization, transport, and uptake of D-aspartate in the rat adrenal and pituitary glands
Authors: Lee, JA Long, ZQ Nimura, N Iwatsubo, T Imai, K Homma, H
Citation: Ja. Lee et al., Localization, transport, and uptake of D-aspartate in the rat adrenal and pituitary glands, ARCH BIOCH, 385(2), 2001, pp. 242-249
Selective insolubility of alpha-Synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model
Authors: Kahle, PJ Neumann, M Ozmen, L Muller, V Odoy, S Okamoto, N Jacobsen, H Iwatsubo, T Trojanowski, JQ Takahashi, H Wakabayashi, K Bogdanovic, N Riederer, P Kretzschmar, HA Haass, C
Citation: Pj. Kahle et al., Selective insolubility of alpha-Synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model, AM J PATH, 159(6), 2001, pp. 2215-2225
Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease
Authors: Mann, DMA Pickering-Brown, SM Takeuchi, A Iwatsubo, T
Citation: Dma. Mann et al., Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease, AM J PATH, 158(6), 2001, pp. 2165-2175
Co-localization of alpha-synuclein and phosphorylated tan in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration
Authors: Piao, YS Hayashi, S Hasegawa, M Wakabayashi, K Yamada, M Yoshimoto, M Ishikawa, A Iwatsubo, T Takahashi, H
Citation: Ys. Piao et al., Co-localization of alpha-synuclein and phosphorylated tan in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration, ACT NEUROP, 101(3), 2001, pp. 285-293
Separation of aromatic isomers on cyclophane-bonded stationary phases
Authors: Shinbo, T Shimabukuro, Y Kanamori, T Iwatsubo, T Nagawa, Y Hiratani, K
Citation: T. Shinbo et al., Separation of aromatic isomers on cyclophane-bonded stationary phases, J CHROMAT A, 877(1-2), 2000, pp. 61-69
Increased levels of apolipoprotein E mRNA in the brains of patients with Down's syndrome
Authors: Yamagata, K Urakami, K Wakutani, Y Adachi, Y Iwatsubo, T Mann, DMA Sato, K Nakashima, K
Citation: K. Yamagata et al., Increased levels of apolipoprotein E mRNA in the brains of patients with Down's syndrome, ALZHEIM REP, 3(2), 2000, pp. 77-82
Molecular interactions between presenilin and calpain: Inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain
Authors: Maruyama, K Usami, M Kametani, F Tomita, T Iwatsubo, T Saido, TC Mori, H Ishiura, S
Citation: K. Maruyama et al., Molecular interactions between presenilin and calpain: Inhibition of m-calpain protease activity by presenilin-1, 2 and cleavage of presenilin-1 by m-, mu-calpain, INT J MOL M, 5(3), 2000, pp. 269-273
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease
Authors: Takahashi, M Dore, S Ferris, CD Tomita, T Sawa, A Wolosker, H Borchelt, DR Iwatsubo, T Kim, SH Thinakaran, G Sisodia, SS Snyder, SH
Citation: M. Takahashi et al., Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease, NEURON, 28(2), 2000, pp. 461-473
Pick's disease is associated with mutations in the tau gene
Authors: Pickering-Brown, S Baker, M Yen, SH Liu, WK Hasegawa, M Cairns, N Lantos, PL Rossor, M Iwatsubo, T Davies, Y Allsop, D Furlong, R Owen, F Hardy, J Mann, D Hutton, M
Citation: S. Pickering-brown et al., Pick's disease is associated with mutations in the tau gene, ANN NEUROL, 48(6), 2000, pp. 859-867
A novel mutation at position+12 in the intron following exon 10 of the taugene in familial frontotemporal dementia (FTD-Kumamoto)
Authors: Yasuda, M Takamatsu, J D'Souza, I Crowther, RA Kawamata, T Hasegawa, M Hasegawa, H Spillantini, MG Tanimukai, S Poorkaj, P Varani, L Varani, G Iwatsubo, T Goedert, M Schellenberg, GD Tanaka, C
Citation: M. Yasuda et al., A novel mutation at position+12 in the intron following exon 10 of the taugene in familial frontotemporal dementia (FTD-Kumamoto), ANN NEUROL, 47(4), 2000, pp. 422-429
Risultati: 1-25 | 26-50 | 51-58