Authors:
STAHL F
WENDE W
WENZ C
JELTSCH A
PINGOUD A
Citation: F. Stahl et al., INTRASUBUNIT VS INTERSUBUNIT COMMUNICATION IN THE HOMODIMERIC RESTRICTION ENZYME ECORV - THR-37 AND LYS-38 INVOLVED IN INDIRECT READOUT AREONLY IMPORTANT FOR THE CATALYTIC ACTIVITY OF THEIR OWN SUBUNIT, Biochemistry, 37(16), 1998, pp. 5682-5688
Citation: F. Stahl et al., THE MECHANISM OF DNA CLEAVAGE BY THE TYPE-II RESTRICTION ENZYME ECORV- ASP36 IS NOT DIRECTLY INVOLVED IN DNA CLEAVAGE BUT SERVES TO COUPLEINDIRECT READOUT TO CATALYSIS, Biological chemistry, 379(4-5), 1998, pp. 467-473
Citation: T. Friedrich et al., FUNCTIONAL MAPPING OF THE ECORV DNA METHYLTRANSFERASE BY RANDOM MUTAGENESIS AND SCREENING FOR CATALYTICALLY INACTIVE MUTANTS, Biological chemistry, 379(4-5), 1998, pp. 475-480
Citation: A. Jeltsch, FLEXIBILITY OF DNA IN COMPLEX WITH PROTEINS DEDUCED FROM THE DISTRIBUTION OF BENDING ANGLES OBSERVED BY SCANNING FORCE MICROSCOPY, Biophysical chemistry, 74(1), 1998, pp. 53-57
Citation: T. Lanio et al., TOWARDS THE DESIGN OF RARE CUTTING RESTRICTION ENDONUCLEASES - USING DIRECTED EVOLUTION TO GENERATE VARIANTS OF ECORV DIFFERING IN THEIR SUBSTRATE-SPECIFICITY BY 2 ORDERS OF MAGNITUDE, Journal of Molecular Biology, 283(1), 1998, pp. 59-69
Citation: A. Jeltsch et al., KINETICS OF METHYLATION AND BINDING OF DNA BY THE ECORV ADENINE-N-6 METHYLTRANSFERASE, Journal of Molecular Biology, 275(5), 1998, pp. 747-758
Citation: M. Roth et al., FUNCTIONAL ROLES OF CONSERVED AMINO-ACID-RESIDUES IN DNA METHYLTRANSFERASES INVESTIGATED BY SITE-DIRECTED MUTAGENESIS OF THE ECORV ADENINE-N-6-METHYLTRANSFERASE, The Journal of biological chemistry, 273(28), 1998, pp. 17333-17342
Authors:
SCHOTTLER S
WENZ C
LANIO T
JELTSCH A
PINGOUD A
Citation: S. Schottler et al., PROTEIN ENGINEERING OF THE RESTRICTION-ENDONUCLEASE ECORV - STRUCTURE-GUIDED DESIGN OF ENZYME VARIANTS THAT RECOGNIZE THE BASE-PAIRS FLANKING THE RECOGNITION SITE, European journal of biochemistry, 258(1), 1998, pp. 184-191
Authors:
LEISMANN O
ROTH M
FRIEDRICH T
WENDE W
JELTSCH A
Citation: O. Leismann et al., THE FLAVOBACTERIUM-OKEANOKOITES ADENINE-N-6-SPECIFIC DNA-METHYLTRANSFERASE M.FOKI IS A TANDEM ENZYME OF 2 INDEPENDENT DOMAINS WITH VERY DIFFERENT KINETIC-PROPERTIES, European journal of biochemistry, 251(3), 1998, pp. 899-906
Citation: A. Jeltsch et A. Pingoud, KINETIC CHARACTERIZATION OF LINEAR DIFFUSION OF THE RESTRICTION-ENDONUCLEASE ECORV ON DNA, Biochemistry, 37(8), 1998, pp. 2160-2169
Citation: A. Pingoud et A. Jeltsch, RECOGNITION AND CLEAVAGE OF DNA BY TYPE-II RESTRICTION ENDONUCLEASES, European journal of biochemistry, 246(1), 1997, pp. 1-22
Citation: Dh. Groll et al., DOES THE RESTRICTION-ENDONUCLEASE ECORV EMPLOY A 2-METAL-ION MECHANISM FOR DNA CLEAVAGE, Biochemistry, 36(38), 1997, pp. 11389-11401
Citation: A. Jeltsch et al., STRUCTURE PREDICTION OF THE ECORV DNA METHYLTRANSFERASE BASED ON MUTANT PROFILING, SECONDARY STRUCTURE-ANALYSIS, COMPARISON WITH KNOWN STRUCTURES OF METHYLTRANSFERASES AND ISOLATION OF CATALYTICALLY INACTIVE SINGLE MUTANTS, Protein engineering, 9(5), 1996, pp. 413-423
Citation: A. Jeltsch et al., LINEAR DIFFUSION OF THE RESTRICTION-ENDONUCLEASE ECORV ON DNA IS ESSENTIAL FOR THE IN-VIVO FUNCTION OF THE ENZYME, EMBO journal, 15(18), 1996, pp. 5104-5111
Authors:
JELTSCH A
WENZ C
WENDE W
SELENT U
PINGOUD A
Citation: A. Jeltsch et al., ENGINEERING NOVEL RESTRICTION ENDONUCLEASES - PRINCIPLES AND APPLICATIONS, Trends in biotechnology, 14(7), 1996, pp. 235-238
Citation: A. Jeltsch et A. Pingoud, HORIZONTAL GENE-TRANSFER CONTRIBUTES TO THE WIDE DISTRIBUTION AND EVOLUTION OF TYPE-II RESTRICTION-MODIFICATION SYSTEMS, Journal of molecular evolution, 42(2), 1996, pp. 91-96
Citation: C. Wenz et al., PROBING THE INDIRECT READOUT OF THE RESTRICTION ENZYME ECORV - MUTATIONAL ANALYSIS OF CONTACTS TO THE DNA BACKBONE, The Journal of biological chemistry, 271(10), 1996, pp. 5565-5573
Authors:
GRABOWSKI G
JELTSCH A
WOLFES H
MAASS G
ALVES J
Citation: G. Grabowski et al., SITE-DIRECTED MUTAGENESIS IN THE CATALYTIC CENTER OF THE RESTRICTION-ENDONUCLEASE ECORI, Gene, 157(1-2), 1995, pp. 113-118
Authors:
JELTSCH A
PLECKAITYTE M
SELENT U
WOLFES H
SIKSNYS V
PINGOUD A
Citation: A. Jeltsch et al., EVIDENCE FOR SUBSTRATE-ASSISTED CATALYSIS IN THE DNA CLEAVAGE OF SEVERAL RESTRICTION ENDONUCLEASES, Gene, 157(1-2), 1995, pp. 157-162
Authors:
JELTSCH A
ALVES J
URBANKE C
MAASS G
ECKSTEIN H
ZHANG LS
BAYER E
PINGOUD A
Citation: A. Jeltsch et al., A DODECAPEPTIDE COMPRISING THE EXTENDED CHAIN-ALPHA-4 REGION OF THE RESTRICTION-ENDONUCLEASE ECORI SPECIFICALLY BINDS TO THE ECORI RECOGNITION SITE, The Journal of biological chemistry, 270(10), 1995, pp. 5122-5129
Authors:
JELTSCH A
MASCHKE H
SELENT U
WENZ C
KOHLER E
CONNOLLY BA
THOROGOOD H
PINGOUD A
Citation: A. Jeltsch et al., DNA-BINDING SPECIFICITY OF THE ECORV RESTRICTION-ENDONUCLEASE IS INCREASED BY MG2-ION BINDING-SITE DISTINCT FROM THE CATALYTIC CENTER OF THE ENZYME( BINDING TO A METAL), Biochemistry, 34(18), 1995, pp. 6239-6246
Authors:
WENZ C
SELENT U
WENDE W
JELTSCH A
WOLFES H
PINGOUD A
Citation: C. Wenz et al., PROTEIN ENGINEERING OF THE RESTRICTION-ENDONUCLEASE ECORV - REPLACEMENT OF AN AMINO-ACID RESIDUE IN THE DNA-BINDING SITE LEADS TO AN ALTERED SELECTIVITY TOWARDS UNMODIFIED AND MODIFIED SUBSTRATES, Biochimica et biophysica acta, N. Gene structure and expression, 1219(1), 1994, pp. 73-80
Authors:
JELTSCH A
ALVES J
WOLFES H
MAASS G
PINGOUD A
Citation: A. Jeltsch et al., SUBSTRATE-ASSISTED CATALYSIS IN THE CLEAVAGE OF DNA BY THE ECORI AND ECORV RESTRICTION ENZYMES, Proceedings of the National Academy of Sciences of the United Statesof America, 90(18), 1993, pp. 8499-8503