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Results: 1-25 | 26-30
Results: 1-25/30
SYNTHESIS OF BISINDOLYLMALEIMIDES USING A PALLADIUM-CATALYZED CROSS-COUPLING REACTION
Authors: NEEL DA JIROUSEK MR MCDONALD JH
Citation: Da. Neel et al., SYNTHESIS OF BISINDOLYLMALEIMIDES USING A PALLADIUM-CATALYZED CROSS-COUPLING REACTION, Bioorganic & medicinal chemistry letters, 8(1), 1998, pp. 47-50
MACROCYCLIC BISINDOLYLMALEIMIDES - SYNTHESIS BY INTERMOLECULAR AND INTRAMOLECULAR ALKYLATION
Authors: FAUL MM WINNEROSKI LL KRUMRICH CA SULLIVAN KA GILLIG JR NEEL DA RITO CJ JIROUSEK MR
Citation: Mm. Faul et al., MACROCYCLIC BISINDOLYLMALEIMIDES - SYNTHESIS BY INTERMOLECULAR AND INTRAMOLECULAR ALKYLATION, Journal of organic chemistry, 63(6), 1998, pp. 1961-1973
CARBACHOL RESTORES INSULIN RELEASE IN SPONTANEOUSLY DIABETIC GK (GOTO-KAKIZAKI) RAT ISLETS BY A MECHANISM LARGELY INVOLVING RAPID HYDROLYSIS OF DIACYLGLYCEROL TO ARACHIDONIC-ACID
Authors: GUENIFI A ABDELHALIM SM JIROUSEK MR EFENDIC S
Citation: A. Guenifi et al., CARBACHOL RESTORES INSULIN RELEASE IN SPONTANEOUSLY DIABETIC GK (GOTO-KAKIZAKI) RAT ISLETS BY A MECHANISM LARGELY INVOLVING RAPID HYDROLYSIS OF DIACYLGLYCEROL TO ARACHIDONIC-ACID, Diabetologia, 41, 1998, pp. 530-530
ABNORMALITIES OF RETINAL METABOLISM IN DIABETES OR EXPERIMENTAL GALACTOSEMIA V - RELATIONSHIP BETWEEN PROTEIN-KINASE-C AND ATPASES
Authors: KOWLURU RA JIROUSEK MR STRAMM L FARID N ENGERMAN RL KERN TS
Citation: Ra. Kowluru et al., ABNORMALITIES OF RETINAL METABOLISM IN DIABETES OR EXPERIMENTAL GALACTOSEMIA V - RELATIONSHIP BETWEEN PROTEIN-KINASE-C AND ATPASES, Diabetes, 47(3), 1998, pp. 464-469
PROTEIN-KINASE-C (PKC) ISOFORMS DIFFERENTIALLY REGULATE THROMBIN-INDUCED THROMBOXANE (TX) PRODUCTION BY HUMAN PLATELETES
Authors: SAMOKHIN GP HENRIKSEN RA JIROUSEK MR WAYS DK
Citation: Gp. Samokhin et al., PROTEIN-KINASE-C (PKC) ISOFORMS DIFFERENTIALLY REGULATE THROMBIN-INDUCED THROMBOXANE (TX) PRODUCTION BY HUMAN PLATELETES, The FASEB journal, 11(3), 1997, pp. 1806-1806
TARGETED OVEREXPRESSION OF PROTEIN-KINASE-C BETA-2 ISOFORM IN MYOCARDIUM CAUSES CARDIOMYOPATHY
Authors: WAKASAKI H KOYA D SCHOEN FJ JIROUSEK MR WAYS DK HOIT BD WALSH RA KING GL
Citation: H. Wakasaki et al., TARGETED OVEREXPRESSION OF PROTEIN-KINASE-C BETA-2 ISOFORM IN MYOCARDIUM CAUSES CARDIOMYOPATHY, Proceedings of the National Academy of Sciences of the United Statesof America, 94(17), 1997, pp. 9320-9325
CHARACTERIZATION OF PROTEIN-KINASE-C BETA-ISOFORM ACTIVATION ON THE GENE-EXPRESSION OF TRANSFORMING GROWTH-FACTOR-BETA, EXTRACELLULAR-MATRIX COMPONENTS, AND PROSTANOIDS IN THE GLOMERULI OF DIABETIC RATS
Authors: KOYA D JIROUSEK MR LIN YW ISHII H KUBOKI K KING GL
Citation: D. Koya et al., CHARACTERIZATION OF PROTEIN-KINASE-C BETA-ISOFORM ACTIVATION ON THE GENE-EXPRESSION OF TRANSFORMING GROWTH-FACTOR-BETA, EXTRACELLULAR-MATRIX COMPONENTS, AND PROSTANOIDS IN THE GLOMERULI OF DIABETIC RATS, The Journal of clinical investigation, 100(1), 1997, pp. 115-126
THE IMIDAZOLINE RX871024 AND THE SECRETIN GLP-1 INDUCE GLUCOSE-DEPENDENT INSULIN-SECRETION IN BETA-TC-6 CELLS
Authors: SCHLOOS J STECKEL B RAAP A JIROUSEK MR GOLD G MEST HJ
Citation: J. Schloos et al., THE IMIDAZOLINE RX871024 AND THE SECRETIN GLP-1 INDUCE GLUCOSE-DEPENDENT INSULIN-SECRETION IN BETA-TC-6 CELLS, Diabetologia, 40, 1997, pp. 407-407
EFFECT OF NEUROENDOCRINOLOGICAL AND 2ND-MESSENGER SIGNALS ON INSULIN-SECRETION IN BETA-TC CELLS
Authors: WILLIAMS VK GONZALEZ CM GOLD G STRAMM LE SCHLOOS J JIROUSEK MR
Citation: Vk. Williams et al., EFFECT OF NEUROENDOCRINOLOGICAL AND 2ND-MESSENGER SIGNALS ON INSULIN-SECRETION IN BETA-TC CELLS, Diabetologia, 40, 1997, pp. 416-416
EFFECT OF PROTEIN-KINASE C-BETA SELECTIVE INHIBITORS ON INSULIN-SECRETION AND BETA-CELL ACTIVITY
Authors: GONZALEZ CM WILLIAMS VK GOLD G STRAMM LE JIROUSEK MR
Citation: Cm. Gonzalez et al., EFFECT OF PROTEIN-KINASE C-BETA SELECTIVE INHIBITORS ON INSULIN-SECRETION AND BETA-CELL ACTIVITY, Diabetologia, 40, 1997, pp. 443-443
CHARACTERIZATION OF THE ROLE OF PKC-BETA IN THE REGULATION OF EXTRACELLULAR-MATRIX ABNORMALITIES IN DIABETIC RATS
Authors: KOYA D JIROUSEK MR ISHII H KING GL
Citation: D. Koya et al., CHARACTERIZATION OF THE ROLE OF PKC-BETA IN THE REGULATION OF EXTRACELLULAR-MATRIX ABNORMALITIES IN DIABETIC RATS, Journal of the American Society of Nephrology, 7(9), 1996, pp. 3139-3139
MIMICKING OF ABNORMAL RETINAL HEMODYNAMICS IN DIABETES BY ENHANCING DAG-PKC LEVELS IN THE RETINA OF NONDIABETIC
Authors: TAKAGI C BURSELL SE CLERMONT AC TAKAGI H JIROUSEK MR KING GL
Citation: C. Takagi et al., MIMICKING OF ABNORMAL RETINAL HEMODYNAMICS IN DIABETES BY ENHANCING DAG-PKC LEVELS IN THE RETINA OF NONDIABETIC, Investigative ophthalmology & visual science, 37(3), 1996, pp. 4291-4291
AMELIORATION OF VASCULAR DYSFUNCTIONS IN DIABETIC RATS BY AN ORAL PKC-BETA INHIBITOR
Authors: ISHII H JIROUSEK MR KOYA D TAKAGI C XIA P CLERMONT A BURSELL SE KERN TS BALLAS LM HEATH WF STRAMM LE FEENER EP KING GL
Citation: H. Ishii et al., AMELIORATION OF VASCULAR DYSFUNCTIONS IN DIABETIC RATS BY AN ORAL PKC-BETA INHIBITOR, Science, 272(5262), 1996, pp. 728-731
[(DIMETHYLAMINO)METHYL]-10,11,14,15-TETRAHYDRO-4,9 ,4-H][1,4,13]OXADIAZACYCLOHEXADECENE-1,3(2H)-DIONE (LY333531) AND RELATED ANALOGS - ISOZYME-SELECTIVE INHIBITORS OF PROTEIN-KINASE C-BETA/
Authors: JIROUSEK MR GILLIG JR GONZALEZ CM HEATH WF MCDONALD JH NEEL DA RITO CJ SINGH U STRAMM LE MELIKIANBADALIAN A BAEVSKY M BALLAS LM HALL SE WINNEROSKI LL FAUL MM
Citation: Mr. Jirousek et al., [(DIMETHYLAMINO)METHYL]-10,11,14,15-TETRAHYDRO-4,9 ,4-H][1,4,13]OXADIAZACYCLOHEXADECENE-1,3(2H)-DIONE (LY333531) AND RELATED ANALOGS - ISOZYME-SELECTIVE INHIBITORS OF PROTEIN-KINASE C-BETA/, Journal of medicinal chemistry, 39(14), 1996, pp. 2664-2671
CHARACTERIZATION OF VASCULAR ENDOTHELIAL GROWTH-FACTORS EFFECT ON THEACTIVATION OF PROTEIN-KINASE-C, ITS ISOFORMS, AND ENDOTHELIAL-CELL GROWTH
Authors: XIA P AIELLO LP ISHII H JIANG ZY PARK DJ ROBINSON GS TAKAGI H NEWSOME WP JIROUSEK MR KING GL
Citation: P. Xia et al., CHARACTERIZATION OF VASCULAR ENDOTHELIAL GROWTH-FACTORS EFFECT ON THEACTIVATION OF PROTEIN-KINASE-C, ITS ISOFORMS, AND ENDOTHELIAL-CELL GROWTH, The Journal of clinical investigation, 98(9), 1996, pp. 2018-2026
DIABETES-INDUCED DISORDERS OF RETINAL PROTEIN-KINASE-C AND NA,K-ATPASE ARE INHIBITED BY LY333531
Authors: KOWLURU RA JIROUSEK MR STRAMM L ENGERMAN RL KERN TS
Citation: Ra. Kowluru et al., DIABETES-INDUCED DISORDERS OF RETINAL PROTEIN-KINASE-C AND NA,K-ATPASE ARE INHIBITED BY LY333531, Diabetes, 45, 1996, pp. 50-50
NORMALIZATION OF HYPERGLYCEMIA-INDUCED-INHIBITION OF NA-K+ ATPASE ACTIVITY BY PROTEIN-KINASE-C (PKC)BETA-SELECTIVE INHIBITOR IN GLOMERULAR MESANGIAL CELLS()
Authors: KOYA D ISHII H JIROUSEK MR KING GL
Citation: D. Koya et al., NORMALIZATION OF HYPERGLYCEMIA-INDUCED-INHIBITION OF NA-K+ ATPASE ACTIVITY BY PROTEIN-KINASE-C (PKC)BETA-SELECTIVE INHIBITOR IN GLOMERULAR MESANGIAL CELLS(), Diabetes, 45, 1996, pp. 478-478
TREATMENT WITH PROTEIN-KINASE-C BETA-ISOFORM INHIBITOR NORMALIZED URINARY ALBUMIN EXCRETION AND GLOMERULAR-FILTRATION RATE IN DIABETIC RATS
Authors: ISHII H KOYA D JIROUSEK MR KING GL
Citation: H. Ishii et al., TREATMENT WITH PROTEIN-KINASE-C BETA-ISOFORM INHIBITOR NORMALIZED URINARY ALBUMIN EXCRETION AND GLOMERULAR-FILTRATION RATE IN DIABETIC RATS, Diabetes, 45, 1996, pp. 479-479
PREVENTION OF ABNORMAL RENAL AND RETINAL FUNCTIONS IN DIABETIC RATS BY AN ORALLY-ACTIVE ISOFORM-SPECIFIC INHIBITOR OF PROTEIN-KINASE-C (PKC)
Authors: ISHII H TAKAGI C KOYA D JIROUSEK MR STRAMM L BURSELL SE KING GL
Citation: H. Ishii et al., PREVENTION OF ABNORMAL RENAL AND RETINAL FUNCTIONS IN DIABETIC RATS BY AN ORALLY-ACTIVE ISOFORM-SPECIFIC INHIBITOR OF PROTEIN-KINASE-C (PKC), Journal of the American Society of Nephrology, 6(3), 1995, pp. 1041-1041
SYNTHESIS OF BISINDOLYLMALEIMIDE MACROCYCLES
Authors: JIROUSEK MR GILLIG JR NEEL DA RITO CJ OBANNON D HEATH WF MCDONALD JH FAUL MM WINNEROSKI LL MELIKIANBADALIAN A BAEVSKY M BALLAS LM HALL SE
Citation: Mr. Jirousek et al., SYNTHESIS OF BISINDOLYLMALEIMIDE MACROCYCLES, Bioorganic & medicinal chemistry letters, 5(18), 1995, pp. 2093-2096
VITAMIN-E PREVENTS DIABETES-INDUCED ABNORMAL RETINAL BLOOD-FLOW VIA THE DIACYLGLYCEROL-PROTEIN KINASE-C PATHWAY
Authors: KUNISAKI M BURSELL SE CLERMONT AC ISHII H BALLAS LM JIROUSEK MR UMEDA F NAWATA H KING GL
Citation: M. Kunisaki et al., VITAMIN-E PREVENTS DIABETES-INDUCED ABNORMAL RETINAL BLOOD-FLOW VIA THE DIACYLGLYCEROL-PROTEIN KINASE-C PATHWAY, American journal of physiology: endocrinology and metabolism, 32(2), 1995, pp. 239-246
A PKC-BETA ISOFORM SELECTIVE ANTAGONIST NORMALIZED RETINAL BLOOD-FLOWIN STZ DIABETIC RATS - 1ST REPORT OF AN ORAL-AGENT SELECTIVE FOR THE PKC-BETA ISOENZYME
Authors: CLERMONT AC TAKAGI C JIROUSEK MR BURSELL SE KING GL
Citation: Ac. Clermont et al., A PKC-BETA ISOFORM SELECTIVE ANTAGONIST NORMALIZED RETINAL BLOOD-FLOWIN STZ DIABETIC RATS - 1ST REPORT OF AN ORAL-AGENT SELECTIVE FOR THE PKC-BETA ISOENZYME, Investigative ophthalmology & visual science, 36(4), 1995, pp. 173-173
NORMALIZATION OF VASCULAR CELL GENE-EXPRESSION AND BLOOD-FLOW BY SPECIFIC INHIBITORS OF DIACYLGLYCEROL-PROTEIN KINASE-C
Authors: KING GL BURSELL SE ISHII H TAKAGI C KUNISAKI M JIROUSEK MR KOYA D
Citation: Gl. King et al., NORMALIZATION OF VASCULAR CELL GENE-EXPRESSION AND BLOOD-FLOW BY SPECIFIC INHIBITORS OF DIACYLGLYCEROL-PROTEIN KINASE-C, Diabetologia, 38, 1995, pp. 261-261
NORMALIZATION OF RETINAL BLOOD-FLOW IN DIABETIC RATS BY ORAL INTAKE OF AN ISOFORM-SELECTIVE INHIBITOR OF PROTEIN-KINASE-C (PKC)
Authors: ISHII H TAKAGI C JIROUSEK MR CLERMONT A STRAMM L BURSELL SE KING GL
Citation: H. Ishii et al., NORMALIZATION OF RETINAL BLOOD-FLOW IN DIABETIC RATS BY ORAL INTAKE OF AN ISOFORM-SELECTIVE INHIBITOR OF PROTEIN-KINASE-C (PKC), Diabetes, 44, 1995, pp. 54-54
NORMALIZATION OF GLUCOSE-INDUCED GENE-EXPRESSION, CALDESMON, BOTH IN-VITRO AND IN-VIVO BY AN ISOFORM-SELECTIVE PROTEIN-KINASE-C (PKC) INHIBITOR
Authors: KUNISAKI M JIROUSEK MR FEENER EP
Citation: M. Kunisaki et al., NORMALIZATION OF GLUCOSE-INDUCED GENE-EXPRESSION, CALDESMON, BOTH IN-VITRO AND IN-VIVO BY AN ISOFORM-SELECTIVE PROTEIN-KINASE-C (PKC) INHIBITOR, Diabetes, 44, 1995, pp. 59-59
Risultati: 1-25 | 26-30