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Results: 1-7 |
Results: 7
BENZOFURAN DERIVATIVES AS ETA-SELECTIVE, NONPEPTIDE ENDOTHELIN ANTAGONISTS
Authors: KALTENBRONN JS QUIN J REISDORPH BR KLUTCHKO S REYNOLDS EE WELCH KM FLYNN MA DOHERTY AM
Citation: Js. Kaltenbronn et al., BENZOFURAN DERIVATIVES AS ETA-SELECTIVE, NONPEPTIDE ENDOTHELIN ANTAGONISTS, European journal of medicinal chemistry, 32(5), 1997, pp. 425-431
C-TERMINAL MODIFICATIONS OF HISTIDYL-N-BENZYLGLYCINAMIDES TO GIVE IMPROVED INHIBITION OF RAS FARNESYLTRANSFERASE, CELLULAR-ACTIVITY, AND ANTICANCER ACTIVITY IN MICE
Authors: MCNAMARA DJ DOBRUSIN E LEONARD DM SHULER KR KALTENBRONN JS QUIN J BUR S THOMAS CE DOHERTY AM SCHOLTEN JD ZIMMERMAN KK GIBBS BS GOWAN RC LATASH MP LEOPOLD WR PRZYBRANOWSKI SA SEBOLTLEOPOLD JS
Citation: Dj. Mcnamara et al., C-TERMINAL MODIFICATIONS OF HISTIDYL-N-BENZYLGLYCINAMIDES TO GIVE IMPROVED INHIBITION OF RAS FARNESYLTRANSFERASE, CELLULAR-ACTIVITY, AND ANTICANCER ACTIVITY IN MICE, Journal of medicinal chemistry, 40(21), 1997, pp. 3319-3322
EVALUATION OF PHYSICOCHEMICAL PARAMETERS IMPORTANT TO THE ORAL BIOAVAILABILITY OF PEPTIDE-LIKE COMPOUNDS - IMPLICATIONS FOR THE SYNTHESIS OF RENIN INHIBITORS
Authors: HAMILTON HW STEINBAUGH BA STEWART BH CHAN OH SCHMID HL SCHROEDER R RYAN MJ KEISER J TAYLOR MD BLANKLEY CJ KALTENBRONN JS WRIGHT J HICKS J
Citation: Hw. Hamilton et al., EVALUATION OF PHYSICOCHEMICAL PARAMETERS IMPORTANT TO THE ORAL BIOAVAILABILITY OF PEPTIDE-LIKE COMPOUNDS - IMPLICATIONS FOR THE SYNTHESIS OF RENIN INHIBITORS, Journal of medicinal chemistry, 38(9), 1995, pp. 1446-1455
STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE POTENT COMBINED ENDOTHELIN-A ENDOTHELIN-B RECEPTOR ANTAGONIST AC-DDIP(16)-LEU-ASP-ILE-ILE-TRP(21) -DEVELOPMENT OF ENDOTHELIN-B RECEPTOR-SELECTIVE ANTAGONISTS
Authors: CODY WL HE JX DEPUE PL WAITE LA LEONARD DM SEFLER AM KALTENBRONN JS HALEEN SJ WALKER DM FLYNN MA WELCH KM REYNOLDS EE DOHERTY AM
Citation: Wl. Cody et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE POTENT COMBINED ENDOTHELIN-A ENDOTHELIN-B RECEPTOR ANTAGONIST AC-DDIP(16)-LEU-ASP-ILE-ILE-TRP(21) -DEVELOPMENT OF ENDOTHELIN-B RECEPTOR-SELECTIVE ANTAGONISTS, Journal of medicinal chemistry, 38(15), 1995, pp. 2809-2819
DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS
Authors: PLUMMER MS SHAHRIPOUR A KALTENBRONN JS LUNNEY EA STEINBAUGH BA HAMBY JM HAMILTON HW SAWYER TK HUMBLET C DOHERTY AM TAYLOR MD HINGORANI G BATLEY BL RAPUNDALO ST
Citation: Ms. Plummer et al., DESIGN AND SYNTHESIS OF RENIN INHIBITORS - INCORPORATION OF TRANSITION-STATE ISOSTERE SIDE-CHAINS THAT SPAN FROM THE S1 TO THE S3 BINDING POCKETS AND EXAMINATION OF P3-MODIFIED RENIN INHIBITORS, Journal of medicinal chemistry, 38(15), 1995, pp. 2893-2905
ANALYSES OF LIGAND-BINDING IN 5 ENDOTHIAPEPSIN CRYSTAL COMPLEXES AND THEIR USE IN THE DESIGN AND EVALUATION OF NOVEL RENIN INHIBITORS
Authors: LUNNEY EA HAMILTON HW HODGES JC KALTENBRONN JS REPINE JT BADASSO M COOPER JB DEALWIS C WALLACE BA LOWTHER WT DUNN BM HUMBLET C
Citation: Ea. Lunney et al., ANALYSES OF LIGAND-BINDING IN 5 ENDOTHIAPEPSIN CRYSTAL COMPLEXES AND THEIR USE IN THE DESIGN AND EVALUATION OF NOVEL RENIN INHIBITORS, Journal of medicinal chemistry, 36(24), 1993, pp. 3809-3820
RENIN INHIBITORS CONTAINING ALPHA-HETEROATOM AMINO-ACIDS AS P2 RESIDUES
Authors: REPINE JT KALTENBRONN JS DOHERTY AM HAMBY JM HIMMELSBACH RJ KORNBERG BE TAYLOR MD LUNNEY EA HUMBLET C RAPUNDALO ST BATLEY BL RYAN MJ PAINCHAUD CA
Citation: Jt. Repine et al., RENIN INHIBITORS CONTAINING ALPHA-HETEROATOM AMINO-ACIDS AS P2 RESIDUES, Journal of medicinal chemistry, 35(6), 1992, pp. 1032-1042
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