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Results: 1-24 |
Results: 24
MIXED D-2 5-HT2A ANTAGONISM OF COCAINE-INDUCED FACILITATION OF BRAIN-STIMULATION REWARD/
Authors: TSIBULSKY VL GROCKI S DASHEVSKY BA KEHNE JH SCHMIDT CJ SORENSEN SM FRANK RA
Citation: Vl. Tsibulsky et al., MIXED D-2 5-HT2A ANTAGONISM OF COCAINE-INDUCED FACILITATION OF BRAIN-STIMULATION REWARD/, Pharmacology, biochemistry and behavior, 59(2), 1998, pp. 275-280
PRECLINICAL CHARACTERIZATION OF MDL-27,192 AS A POTENTIAL BROAD-SPECTRUM ANTICONVULSANT AGENT WITH NEUROPROTECTIVE PROPERTIES
Authors: KEHNE JH KANE JM CHANEY SF HURST G MCCLOSKEY TC PETTY MA SENYAH Y WOLF HH ZOBRIST R WHITE HS
Citation: Jh. Kehne et al., PRECLINICAL CHARACTERIZATION OF MDL-27,192 AS A POTENTIAL BROAD-SPECTRUM ANTICONVULSANT AGENT WITH NEUROPROTECTIVE PROPERTIES, Epilepsy research, 27(1), 1997, pp. 41-54
THE PERIPHERAL NK-1 NK-2-RECEPTOR ANTAGONIST MDL-105,172A INHIBITS TACHYKININ-MEDIATED RESPIRATORY EFFECTS IN GUINEA-PIGS/
Authors: KUDLACZ EM KNIPPENBERG RW SHATZER SA KEHNE JH MCCLOSKEY TC BURKHOLDER TP
Citation: Em. Kudlacz et al., THE PERIPHERAL NK-1 NK-2-RECEPTOR ANTAGONIST MDL-105,172A INHIBITS TACHYKININ-MEDIATED RESPIRATORY EFFECTS IN GUINEA-PIGS/, Journal of autonomic pharmacology, 17(2), 1997, pp. 109-119
MIXED D-2 5-HT2 ANTAGONISM DIFFERENTIALLY AFFECTS APOMORPHINE-INDUCEDAND AMPHETAMINE-INDUCED STEREOTYPED BEHAVIOR/
Authors: FELDMAN DJ FRANK RA KEHNE JH FLANNERY R BROWN D SONI S BYRD G SHAH S
Citation: Dj. Feldman et al., MIXED D-2 5-HT2 ANTAGONISM DIFFERENTIALLY AFFECTS APOMORPHINE-INDUCEDAND AMPHETAMINE-INDUCED STEREOTYPED BEHAVIOR/, Pharmacology, biochemistry and behavior, 58(2), 1997, pp. 565-572
PHARMACOLOGICAL CHARACTERIZATION OF MDL-105,519, AN NMDA RECEPTOR GLYCINE SITE ANTAGONIST
Authors: BARON BM HARRISON BL KEHNE JH SCHMIDT CJ VANGIERSBERGEN PLM WHITE HS SIEGEL BW SENYAH Y MCCLOSKEY TC FADAYEL GM TAYLOR VL MURAWSKY MK NYCE P SALITURO FG
Citation: Bm. Baron et al., PHARMACOLOGICAL CHARACTERIZATION OF MDL-105,519, AN NMDA RECEPTOR GLYCINE SITE ANTAGONIST, European journal of pharmacology, 323(2-3), 1997, pp. 181-192
5-HT MODULATION OF AUDITORY AND VISUAL SENSORIMOTOR GATING .1. EFFECTS OF 5-HT RELEASERS ON SOUND AND LIGHT PREPULSE INHIBITION IN WISTAR RATS
Authors: KEHNE JH PADICH RA MCCLOSKEY TC TAYLOR VL SCHMIDT CJ
Citation: Jh. Kehne et al., 5-HT MODULATION OF AUDITORY AND VISUAL SENSORIMOTOR GATING .1. EFFECTS OF 5-HT RELEASERS ON SOUND AND LIGHT PREPULSE INHIBITION IN WISTAR RATS, Psychopharmacology, 124(1-2), 1996, pp. 95-106
5-HT MODULATION OF AUDITORY AND VISUAL SENSORIMOTOR GATING .2. EFFECTS OF THE 5-HT2A ANTAGONIST MDL-100,907 ON DISRUPTION OF SOUND AND LIGHT PREPULSE INHIBITION PRODUCED BY 5-HT AGONISTS IN WISTAR RATS
Authors: PADICH RA MCCLOSKEY TC KEHNE JH
Citation: Ra. Padich et al., 5-HT MODULATION OF AUDITORY AND VISUAL SENSORIMOTOR GATING .2. EFFECTS OF THE 5-HT2A ANTAGONIST MDL-100,907 ON DISRUPTION OF SOUND AND LIGHT PREPULSE INHIBITION PRODUCED BY 5-HT AGONISTS IN WISTAR RATS, Psychopharmacology, 124(1-2), 1996, pp. 107-116
RATIONALE FOR THE USE OF A SELECTIVE 5-HT2A RECEPTOR ANTAGONIST IN THE TREATMENT OF SCHIZOPHRENIA
Authors: SCHMIDT CJ FADAYEL GM SORENSEN SM KEHNE JH
Citation: Cj. Schmidt et al., RATIONALE FOR THE USE OF A SELECTIVE 5-HT2A RECEPTOR ANTAGONIST IN THE TREATMENT OF SCHIZOPHRENIA, Schizophrenia research, 18(2-3), 1996, pp. 11-11
PRECLINICAL PROFILE OF MDL-100907, A POTENT AND SELECTIVE 5-HT2A ANTAGONIST IN DEVELOPMENT FOR SCHIZOPHRENIA
Authors: SORENSEN SM CARR AA VANGIERSBERGEN PLM HITCHCOCK JM KEHNE JH SCHMIDT CJ
Citation: Sm. Sorensen et al., PRECLINICAL PROFILE OF MDL-100907, A POTENT AND SELECTIVE 5-HT2A ANTAGONIST IN DEVELOPMENT FOR SCHIZOPHRENIA, Schizophrenia research, 18(2-3), 1996, pp. 13-13
EFFECTS OF THE SELECTIVE 5-HT2A RECEPTOR ANTAGONIST MDL-100,907 ON MDMA-INDUCED LOCOMOTOR STIMULATION IN RATS
Authors: KEHNE JH KETTELER HJ MCCLOSKEY TC SULLIVAN CK DUDLEY MW SCHMIDT CJ
Citation: Jh. Kehne et al., EFFECTS OF THE SELECTIVE 5-HT2A RECEPTOR ANTAGONIST MDL-100,907 ON MDMA-INDUCED LOCOMOTOR STIMULATION IN RATS, Neuropsychopharmacology, 15(2), 1996, pp. 116-124
PRECLINICAL CHARACTERIZATION OF THE POTENTIAL OF THE PUTATIVE ATYPICAL ANTIPSYCHOTIC MDL-100,907 AS A POTENT 5-HT2A ANTAGONIST WITH A FAVORABLE CNS SAFETY PROFILE
Authors: KEHNE JH BARON BM CARR AA CHANEY SF ELANDS J FELDMAN DJ FRANK RA VANGIERSBERGEN PLM MCCLOSKEY TC JOHNSON MP MCCARTY DR POIROT M SENYAH Y SIEGEL BW WIDMAIER C
Citation: Jh. Kehne et al., PRECLINICAL CHARACTERIZATION OF THE POTENTIAL OF THE PUTATIVE ATYPICAL ANTIPSYCHOTIC MDL-100,907 AS A POTENT 5-HT2A ANTAGONIST WITH A FAVORABLE CNS SAFETY PROFILE, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 968-981
CYCLIC NITRONE FREE-RADICAL TRAPS - ISOLATION, IDENTIFICATION, AND SYNTHESIS OF 3,3-DIMETHYL-3,4-DIHYDROISOQUINOLIN-4-OL N-OXIDE, A METABOLITE WITH REDUCED SIDE-EFFECTS
Authors: THOMAS CE BERNARDELLI P BOWEN SM CHANEY SF FRIEDRICH D JANOWICK DA JONES BK KEELEY FJ KEHNE JH KETTELER B OHLWEILER DF PAQUETTE LA ROBKE DJ FEVIG TL
Citation: Ce. Thomas et al., CYCLIC NITRONE FREE-RADICAL TRAPS - ISOLATION, IDENTIFICATION, AND SYNTHESIS OF 3,3-DIMETHYL-3,4-DIHYDROISOQUINOLIN-4-OL N-OXIDE, A METABOLITE WITH REDUCED SIDE-EFFECTS, Journal of medicinal chemistry, 39(25), 1996, pp. 4997-5004
DOPAMINERGIC, GLUTAMATERGIC, AND SEROTONERGIC MODULATION OF SENSORY GATING - USE OF PREPULSE INHIBITION FOR EVALUATING ANTIPSYCHOTIC ACTIVITY AND PSYCHOTOMIMETIC POTENTIAL OF NOVEL THERAPEUTIC COMPOUNDS
Authors: KEHNE JH MCCLOSKEY TC PADICH RA
Citation: Jh. Kehne et al., DOPAMINERGIC, GLUTAMATERGIC, AND SEROTONERGIC MODULATION OF SENSORY GATING - USE OF PREPULSE INHIBITION FOR EVALUATING ANTIPSYCHOTIC ACTIVITY AND PSYCHOTOMIMETIC POTENTIAL OF NOVEL THERAPEUTIC COMPOUNDS, Schizophrenia research, 15(1-2), 1995, pp. 154-154
REVERSAL OF AMPHETAMINE-INDUCED BEHAVIORS BY MDL-100,907, A SELECTIVE5-HT2A ANTAGONIST
Authors: MOSER PC MORAN PM FRANK RA KEHNE JH
Citation: Pc. Moser et al., REVERSAL OF AMPHETAMINE-INDUCED BEHAVIORS BY MDL-100,907, A SELECTIVE5-HT2A ANTAGONIST, Behavioural brain research, 73(1-2), 1995, pp. 163-167
MIXED D-2 5-HT2A ANTAGONISM OF AMPHETAMINE-INDUCED FACILITATION OF BRAIN-STIMULATION REWARD/
Authors: FRANK RA TSIBULSKY V GROCKI S DASHEVSKY B KEHNE JH SCHMIDT CJ SORENSEN SM
Citation: Ra. Frank et al., MIXED D-2 5-HT2A ANTAGONISM OF AMPHETAMINE-INDUCED FACILITATION OF BRAIN-STIMULATION REWARD/, Pharmacology, biochemistry and behavior, 52(4), 1995, pp. 799-804
THE ROLE OF 5-HT2A RECEPTORS IN ANTIPSYCHOTIC ACTIVITY
Authors: SCHMIDT CJ SORENSEN SM KEHNE JH CARR AA PALFREYMAN MG
Citation: Cj. Schmidt et al., THE ROLE OF 5-HT2A RECEPTORS IN ANTIPSYCHOTIC ACTIVITY, Life sciences, 56(25), 1995, pp. 2209-2222
MDL-100,458 AND MDL-102,288 - 2 POTENT AND SELECTIVE GLYCINE RECEPTORANTAGONISTS WITH DIFFERENT FUNCTIONAL PROFILES
Authors: KEHNE JH BARON BM HARRISON BL MCCLOSKEY TC PALFREYMAN MG POIROT M SALITURO FG SIEGEL BW SLONE AL VANGIERSBERGEN PLM WHITE HS
Citation: Jh. Kehne et al., MDL-100,458 AND MDL-102,288 - 2 POTENT AND SELECTIVE GLYCINE RECEPTORANTAGONISTS WITH DIFFERENT FUNCTIONAL PROFILES, European journal of pharmacology, 284(1-2), 1995, pp. 109-118
ANTICONVULSANT PROFILE AND MECHANISM OF ACTION OF THE NOVEL ANTICONVULSANT MDL-27,192 HENYL)-2,4-DIHYDRO-4-ETHYL-3H-1,2,4-TRIAZOL-3-ONE)
Authors: WOLF HH WHITE HS WOODHEAD JH ROGERS CJ OGDEN AM KANE JM KEHNE JH METCALF G
Citation: Hh. Wolf et al., ANTICONVULSANT PROFILE AND MECHANISM OF ACTION OF THE NOVEL ANTICONVULSANT MDL-27,192 HENYL)-2,4-DIHYDRO-4-ETHYL-3H-1,2,4-TRIAZOL-3-ONE), Epilepsia, 36, 1995, pp. 37-37
PRECLINICAL ANTIPSYCHOTIC ACTIVITY OF A SELECTIVE 5HT(2) ANTAGONIST
Authors: SORENSEN SM SCHMIDT CJ HUMPHREYS TM PADICH RA KEHNE JH
Citation: Sm. Sorensen et al., PRECLINICAL ANTIPSYCHOTIC ACTIVITY OF A SELECTIVE 5HT(2) ANTAGONIST, Schizophrenia research, 11(2), 1994, pp. 115-115
5-ARYL-3-(ALKYLTHIO)-4H-1,2,4-TRIAZOLES AS SELECTIVE ANTAGONISTS OF STRYCHNINE-INDUCED CONVULSIONS AND POTENTIAL ANTISPASTIC AGENTS
Authors: KANE JM STAEGER MA DALTON CR MILLER FP DUDLEY MW OGDEN AML KEHNE JH KETTELER HJ MCCLOSKEY TC SENYAH Y CHMIELEWSKI PA MILLER JA
Citation: Jm. Kane et al., 5-ARYL-3-(ALKYLTHIO)-4H-1,2,4-TRIAZOLES AS SELECTIVE ANTAGONISTS OF STRYCHNINE-INDUCED CONVULSIONS AND POTENTIAL ANTISPASTIC AGENTS, Journal of medicinal chemistry, 37(1), 1994, pp. 125-132
ELECTROPHYSIOLOGICAL, BIOCHEMICAL AND BEHAVIORAL EVIDENCE FOR 5-HT(2)AND 5-HT(3) MEDIATED CONTROL OF DOPAMINERGIC FUNCTION
Authors: PALFREYMAN MG SCHMIDT CJ SORENSEN SM DUDLEY MW KEHNE JH MOSER P GITTOS MW CARR AA
Citation: Mg. Palfreyman et al., ELECTROPHYSIOLOGICAL, BIOCHEMICAL AND BEHAVIORAL EVIDENCE FOR 5-HT(2)AND 5-HT(3) MEDIATED CONTROL OF DOPAMINERGIC FUNCTION, Psychopharmacology, 112(1), 1993, pp. 190000060-190000067
CONTRIBUTION OF SEROTONIN NEUROTOXINS TO UNDERSTANDING PSYCHIATRIC-DISORDERS - THE ROLE OF 5-HT2 RECEPTORS IN SCHIZOPHRENIA AND ANTIPSYCHOTIC ACTIVITY
Authors: SCHMIDT CJ KEHNE JH CARR AA FADAYEL GM HUMPHREYS TM KETTLER HJ MCCLOSKEY TC PADICH RA TAYLOR VL SORENSEN SM
Citation: Cj. Schmidt et al., CONTRIBUTION OF SEROTONIN NEUROTOXINS TO UNDERSTANDING PSYCHIATRIC-DISORDERS - THE ROLE OF 5-HT2 RECEPTORS IN SCHIZOPHRENIA AND ANTIPSYCHOTIC ACTIVITY, International clinical psychopharmacology, 8, 1993, pp. 25-32
CHARACTERIZATION OF THE 5-HT(2) RECEPTOR ANTAGONIST MDL 100907 AS A PUTATIVE ATYPICAL ANTIPSYCHOTIC - BEHAVIORAL, ELECTROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES
Authors: SORENSEN SM KEHNE JH FADAYEL GM HUMPHREYS TM KETTELER HJ SULLIVAN CK TAYLOR VL SCHMIDT CJ
Citation: Sm. Sorensen et al., CHARACTERIZATION OF THE 5-HT(2) RECEPTOR ANTAGONIST MDL 100907 AS A PUTATIVE ATYPICAL ANTIPSYCHOTIC - BEHAVIORAL, ELECTROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES, The Journal of pharmacology and experimental therapeutics, 266(2), 1993, pp. 684-691
GLYCINE ANTAGONISTS AS POTENTIAL NOVEL ANXIOLYTIC AGENTS
Authors: KEHNE JH BARON BM HARRISON BL MCDONALD IA PALFREYMAN MG SALITURO FG MCCLOSKEY TC WHITE HS
Citation: Jh. Kehne et al., GLYCINE ANTAGONISTS AS POTENTIAL NOVEL ANXIOLYTIC AGENTS, Journal of neurochemistry, 61, 1993, pp. 190000051-190000051
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