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Results: 1-15 |
Results: 15
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - SYNTHESIS AND BIOLOGICAL-ACTIVITY OF AMIDE AND CYANOGUANIDINE DERIVATIVES CONTAINING A 5,11-DIHYDRO[1]BENZTHIEPIN, BENZOXEPIN, AND BENZAZEPIN [4,3-B]PYRIDINE RING-SYSTEM
Authors: WOLIN R CONNOLLY M KELLY J WEINSTEIN J ROSENBLUM S AFONSO A JAMES L KIRSCHMEIER P BISHOP WR
Citation: R. Wolin et al., INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - SYNTHESIS AND BIOLOGICAL-ACTIVITY OF AMIDE AND CYANOGUANIDINE DERIVATIVES CONTAINING A 5,11-DIHYDRO[1]BENZTHIEPIN, BENZOXEPIN, AND BENZAZEPIN [4,3-B]PYRIDINE RING-SYSTEM, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2521-2526
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - 4-AMIDO, 4-CARBAMOYL, AND 4-CARBOXAMIDO DERIVATIVES OF ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE AND ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE
Authors: MALLAMS AK ROSSMAN RR DOLL RJ GIRIJAVALLABHAN VM GANGULY AK PETRIN J WANG L PATTON R BISHOP WR CARR DM KIRSCHMEIER P CATINO JJ BRYANT MS CHEN KJ KORFMACHER WA NARDO C WANG SY NOMEIR AA LIN CC LI ZJ CHEN JP LEE S DELL J LIPARI P MALKOWSKI M YAREMKO B KING I LIU M
Citation: Ak. Mallams et al., INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - 4-AMIDO, 4-CARBAMOYL, AND 4-CARBOXAMIDO DERIVATIVES OF ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE AND ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE, Journal of medicinal chemistry, 41(6), 1998, pp. 877-893
-PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT())
Authors: NJOROGE FG TAVERAS AG KELLY J REMISZEWSKI S MALLAMS AK WOLIN R AFONSO A COOPER AB RANE DF LIU YT WONG J VIBULBHAN B PINTO P DESKUS J ALVAREZ CS DELROSARIO J CONNOLLY M WANG J DESAI J ROSSMAN RR BISHOP WR PATTON R WANG L KIRSCHMEIER P BRYANT MS NOMEIR AA LIN CC LIU M MCPHAIL AT DOLL RJ GIRIJAVALLABHAN VM GANGULY AK
Citation: Fg. Njoroge et al., -PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT()), Journal of medicinal chemistry, 41(24), 1998, pp. 4890-4902
ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE
Authors: LIU M BRYANT MS CHEN JP LEE SN YAREMKO B LIPARI P MALKOWSKI M FERRARI E NIELSEN L PRIOLI N DELL J SINHA D SYED J KORFMACHER WA NOMEIR AA LIN CC WANG L TAVERAS AG DOLL RJ NJOROGE FG MALLAMS AK REMISZEWSKI S CATINO JJ GIRIJAVALLABHAN VM KIRSCHMEIER P BISHOP WR
Citation: M. Liu et al., ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE, Cancer research, 58(21), 1998, pp. 4947-4956
INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN
Authors: GANGULY AK WANG YS PRAMANIK BN DOLL RJ SNOW ME TAVERAS AG REMISZEWSKI S CESARZ D DELROSARIO J VIBULBHAN B BROWN JE KIRSCHMEIER P HUANG EC HEIMARK L TSARBOPOULOS A GIRIJAVALLABHAN VM AUST RM BROWN EL DELISLE DM FUHRMAN SA HENDRICKSON TF KISSINGER CR LOVE RA SISSON WA VILLAFRANCA JE WEBBER SE
Citation: Ak. Ganguly et al., INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN, Biochemistry (Easton), 37(45), 1998, pp. 15631-15637
DETECTION AND STRUCTURAL CHARACTERIZATION OF RAS ONCOPROTEIN-INHIBITORS COMPLEXES BY ELECTROSPRAY MASS-SPECTROMETRY
Authors: GANGULY AK PRAMANIK BN HUANG EC LIBERLES S HEIMARK L LIU YH TSARBOPOULOS A DOLL RJ TAVERAS AG REMISZEWSKI S SNOW ME WANG YS VIBULBHAN B CESARZ D BROWN JE DELROSARIO J KIRSCHMEIER P GIRIJAVALLABHAN V
Citation: Ak. Ganguly et al., DETECTION AND STRUCTURAL CHARACTERIZATION OF RAS ONCOPROTEIN-INHIBITORS COMPLEXES BY ELECTROSPRAY MASS-SPECTROMETRY, Bioorganic & medicinal chemistry, 5(5), 1997, pp. 817-820
K-RAS AND N-RAS ARE GERANYLGERANYLATED IN CELLS TREATED WITH FARNESYL-PROTEIN TRANSFERASE INHIBITORS
Authors: WHITE DB KIRSCHMEIER P HOCKENBERRY T OLIVA I JAMES L CATINO JJ BISHOP WR PAI JK
Citation: Db. White et al., K-RAS AND N-RAS ARE GERANYLGERANYLATED IN CELLS TREATED WITH FARNESYL-PROTEIN TRANSFERASE INHIBITORS, The FASEB journal, 11(9), 1997, pp. 629-629
K-RAS AND N-RAS ARE GERANYLGERANYLATED IN CELLS TREATED WITH FARNESYL-PROTEIN TRANSFERASE INHIBITORS
Authors: WHYTE DB KIRSCHMEIER P HOCKENBERRY TN NUNEZOLIVA I JAMES L CATINO JJ BISHOP WR PAI JK
Citation: Db. Whyte et al., K-RAS AND N-RAS ARE GERANYLGERANYLATED IN CELLS TREATED WITH FARNESYL-PROTEIN TRANSFERASE INHIBITORS, The Journal of biological chemistry, 272(22), 1997, pp. 14459-14464
CHARACTERIZATION OF HA-RAS, N-RAS, KI-RAS4A, AND KI-RAS4B AS IN-VITROSUBSTRATES FOR FARNESYL-PROTEIN TRANSFERASE AND GERANYLGERANYL PROTEIN TRANSFERASE TYPE-I
Authors: ZHANG FL KIRSCHMEIER P CARR D JAMES L BOND RW WANG L PATTON R WINDSOR WT SYTO R ZHANG RM BISHOP WR
Citation: Fl. Zhang et al., CHARACTERIZATION OF HA-RAS, N-RAS, KI-RAS4A, AND KI-RAS4B AS IN-VITROSUBSTRATES FOR FARNESYL-PROTEIN TRANSFERASE AND GERANYLGERANYL PROTEIN TRANSFERASE TYPE-I, The Journal of biological chemistry, 272(15), 1997, pp. 10232-10239
THE TRICYCLIC FARNESYL TRANSFERASE INHIBITOR SCH44342 BLOCKS CELLULAR-TRANSFORMATION BY H-RAS
Authors: KIRSCHMEIER P ARMSTRONG L JAMES L CARR D ZANG F DOLL R NJOROGE G DALTON M SINENSKY M BISHOP R
Citation: P. Kirschmeier et al., THE TRICYCLIC FARNESYL TRANSFERASE INHIBITOR SCH44342 BLOCKS CELLULAR-TRANSFORMATION BY H-RAS, Molecular biology of the cell, 7, 1996, pp. 2986-2986
SYNTHESIS AND EVALUATION OF PYRAZOLO [3,4-B]QUINOLINE RIBOFURANOSIDESAND THEIR DERIVATIVES AS INHIBITORS OF ONCOGENIC RAS
Authors: WOLIN R WANG D KELLY J AFONSO A JAMES L KIRSCHMEIER P MCPHAIL AT
Citation: R. Wolin et al., SYNTHESIS AND EVALUATION OF PYRAZOLO [3,4-B]QUINOLINE RIBOFURANOSIDESAND THEIR DERIVATIVES AS INHIBITORS OF ONCOGENIC RAS, Bioorganic & medicinal chemistry letters, 6(2), 1996, pp. 195-200
CHEMICAL-SHIFT ASSIGNMENTS AND SECONDARY STRUCTURE OF THE GRB2 SH2 DOMAIN BY HETERONUCLEAR NMR-SPECTROSCOPY
Authors: WANG YS FREDERICK AF SENIOR MM LYONS BA BLACK S KIRSCHMEIER P PERKINS LM WILSON O
Citation: Ys. Wang et al., CHEMICAL-SHIFT ASSIGNMENTS AND SECONDARY STRUCTURE OF THE GRB2 SH2 DOMAIN BY HETERONUCLEAR NMR-SPECTROSCOPY, Journal of biomolecular NMR, 7(2), 1996, pp. 89-98
CHARACTERIZATION OF UPA-R TRANSFECTANTS
Authors: CILIBERTI JL HAILEY JA BLOOD CH KIRSCHMEIER P
Citation: Jl. Ciliberti et al., CHARACTERIZATION OF UPA-R TRANSFECTANTS, Molecular biology of the cell, 6, 1995, pp. 1608-1608
NOVEL TRICYCLIC INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - BIOCHEMICAL-CHARACTERIZATION AND INHIBITION OF RAS MODIFICATION IN TRANSFECTEDCOS CELLS
Authors: BISHOP WR BOND R PETRIN J WANG L PATTON R DOLL R NJOROGE G CATINO J SCHWARTZ J WINDSOR W SYTO R SCHWARTZ J CARR D JAMES L KIRSCHMEIER P
Citation: Wr. Bishop et al., NOVEL TRICYCLIC INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - BIOCHEMICAL-CHARACTERIZATION AND INHIBITION OF RAS MODIFICATION IN TRANSFECTEDCOS CELLS, The Journal of biological chemistry, 270(51), 1995, pp. 30611-30618
INDOLOCARBAZOLES .1. TOTAL SYNTHESIS AND PROTEIN-KINASE INHIBITING CHARACTERISTICS OF COMPOUNDS RELATED TO K-252C
Authors: MCCOMBIE SW BISHOP RW CARR D DOBEK E KIRKUP MP KIRSCHMEIER P LIN SI PETRIN J ROSINSKI K SHANKAR BB WILSON O
Citation: Sw. Mccombie et al., INDOLOCARBAZOLES .1. TOTAL SYNTHESIS AND PROTEIN-KINASE INHIBITING CHARACTERISTICS OF COMPOUNDS RELATED TO K-252C, Bioorganic & medicinal chemistry letters, 3(8), 1993, pp. 1537-1542
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