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Results: 1-24 |
Results: 24
A REDOX PATHWAY LEADING TO THE ALKYLATION OF NUCLEIC-ACIDS BY DOXORUBICIN AND RELATED ANTHRACYCLINES - APPLICATION TO THE DESIGN OF ANTITUMOR DRUGS FOR RESISTANT CANCER
Authors: TAATJES DJ FENICK DJ GAUDIANO G KOCH TH
Citation: Dj. Taatjes et al., A REDOX PATHWAY LEADING TO THE ALKYLATION OF NUCLEIC-ACIDS BY DOXORUBICIN AND RELATED ANTHRACYCLINES - APPLICATION TO THE DESIGN OF ANTITUMOR DRUGS FOR RESISTANT CANCER, Current pharmaceutical design, 4(3), 1998, pp. 203-218
CARBONYL AND THIOCARBONYL STABILIZED 1,4-DIHYDROPYRAZINES - SYNTHESISAND CHARACTERIZATION
Authors: BROOK DJR NOLL BC KOCH TH
Citation: Djr. Brook et al., CARBONYL AND THIOCARBONYL STABILIZED 1,4-DIHYDROPYRAZINES - SYNTHESISAND CHARACTERIZATION, Journal of the Chemical Society. Perkin transactions. I, (2), 1998, pp. 289-292
CYTOPLASMIC LOCALIZATION OF ANTHRACYCLINE ANTITUMOR DRUGS CONJUGATED WITH REDUCED GLUTATHIONE - A POSSIBLE CORRELATION WITH MULTIDRUG-RESISTANCE MECHANISMS
Authors: SERAFINO A SINIBALDIVALLEBONA P GAUDIANO G KOCH TH RASI G GARACI E RAVAGNAN G
Citation: A. Serafino et al., CYTOPLASMIC LOCALIZATION OF ANTHRACYCLINE ANTITUMOR DRUGS CONJUGATED WITH REDUCED GLUTATHIONE - A POSSIBLE CORRELATION WITH MULTIDRUG-RESISTANCE MECHANISMS, Anticancer research, 18(2A), 1998, pp. 1159-1166
EPIDOXOFORM - A HYDROLYTICALLY MORE STABLE ANTHRACYCLINE-FORMALDEHYDECONJUGATE TOXIC TO RESISTANT TUMOR-CELLS
Authors: TAATJES DJ FENICK DJ KOCH TH
Citation: Dj. Taatjes et al., EPIDOXOFORM - A HYDROLYTICALLY MORE STABLE ANTHRACYCLINE-FORMALDEHYDECONJUGATE TOXIC TO RESISTANT TUMOR-CELLS, Journal of medicinal chemistry, 41(8), 1998, pp. 1306-1314
PHOTOCROSS-LINKING OF NUCLEIC-ACIDS TO ASSOCIATED PROTEINS
Authors: MEISENHEIMER KM KOCH TH
Citation: Km. Meisenheimer et Th. Koch, PHOTOCROSS-LINKING OF NUCLEIC-ACIDS TO ASSOCIATED PROTEINS, Critical reviews in biochemistry and molecular biology, 32(2), 1997, pp. 101-140
STRUCTURE AND PROPERTIES OF SOME NEW DIHYDROPYRAZINE-TETRACYANOQUINODIMETHANE CHARGE-TRANSFER SALTS
Authors: BROOK DJR KOCH TH
Citation: Djr. Brook et Th. Koch, STRUCTURE AND PROPERTIES OF SOME NEW DIHYDROPYRAZINE-TETRACYANOQUINODIMETHANE CHARGE-TRANSFER SALTS, Journal of materials chemistry, 7(12), 1997, pp. 2381-2385
PRODUCTION OF FORMALDEHYDE AND DNA-ADRIAMYCIN OR DNA-DAUNOMYCIN ADDUCTS, INITIATED THROUGH REDOX CHEMISTRY OF DITHIOTHREITOL IRON, XANTHINEOXIDASE/NADH/IRON, OR GLUTATHIONE/IRON/
Authors: TAATJES DJ GAUDIANO G KOCH TH
Citation: Dj. Taatjes et al., PRODUCTION OF FORMALDEHYDE AND DNA-ADRIAMYCIN OR DNA-DAUNOMYCIN ADDUCTS, INITIATED THROUGH REDOX CHEMISTRY OF DITHIOTHREITOL IRON, XANTHINEOXIDASE/NADH/IRON, OR GLUTATHIONE/IRON/, Chemical research in toxicology, 10(9), 1997, pp. 953-961
MECHANISTIC STUDIES RELEVANT TO BROMOURIDINE-ENHANCED NUCLEOPROTEIN PHOTO-CROSS-LINKING - POSSIBLE INVOLVEMENT OF AN EXCITED TYROSINE RESIDUE OF THE PROTEIN
Authors: NORRIS CL MEISENHEIMER KM KOCH TH
Citation: Cl. Norris et al., MECHANISTIC STUDIES RELEVANT TO BROMOURIDINE-ENHANCED NUCLEOPROTEIN PHOTO-CROSS-LINKING - POSSIBLE INVOLVEMENT OF AN EXCITED TYROSINE RESIDUE OF THE PROTEIN, Photochemistry and photobiology, 65(2), 1997, pp. 201-207
DIOXYGEN OXIDATION OF A STABLE 1,4-DIHYDROPYRAZINE
Authors: BROOK DJR NOLL BC KOCH TH
Citation: Djr. Brook et al., DIOXYGEN OXIDATION OF A STABLE 1,4-DIHYDROPYRAZINE, Journal of organic chemistry, 62(20), 1997, pp. 6767-6772
REDOX PATHWAY LEADING TO THE ALKYLATION OF DNA BY THE ANTHRACYCLINE, ANTITUMOR DRUGS ADRIAMYCIN AND DAUNOMYCIN
Authors: TAATJES DJ GAUDIANO G RESING K KOCH TH
Citation: Dj. Taatjes et al., REDOX PATHWAY LEADING TO THE ALKYLATION OF DNA BY THE ANTHRACYCLINE, ANTITUMOR DRUGS ADRIAMYCIN AND DAUNOMYCIN, Journal of medicinal chemistry, 40(8), 1997, pp. 1276-1286
DOXOFORM AND DAUNOFORM - ANTHRACYCLINE-FORMALDEHYDE CONJUGATES TOXIC TO RESISTANT TUMOR-CELLS
Authors: FENICK DJ TAATJES DJ KOCH TH
Citation: Dj. Fenick et al., DOXOFORM AND DAUNOFORM - ANTHRACYCLINE-FORMALDEHYDE CONJUGATES TOXIC TO RESISTANT TUMOR-CELLS, Journal of medicinal chemistry, 40(16), 1997, pp. 2452-2461
HIGH-YIELD PHOTO-CROSS-LINKING OF A 5-IODOCYTIDINE (IC) SUBSTITUTED RNA TO ITS ASSOCIATED PROTEIN
Authors: MEISENHEIMER KM MEISENHEIMER PL WILLIS MC KOCH TH
Citation: Km. Meisenheimer et al., HIGH-YIELD PHOTO-CROSS-LINKING OF A 5-IODOCYTIDINE (IC) SUBSTITUTED RNA TO ITS ASSOCIATED PROTEIN, Nucleic acids research, 24(5), 1996, pp. 981-982
ALKYLATION OF DNA BY THE ANTHRACYCLINE, ANTITUMOR DRUGS ADRIAMYCIN AND DAUNOMYCIN
Authors: TAATJES DJ GAUDIANO G RESING K KOCH TH
Citation: Dj. Taatjes et al., ALKYLATION OF DNA BY THE ANTHRACYCLINE, ANTITUMOR DRUGS ADRIAMYCIN AND DAUNOMYCIN, Journal of medicinal chemistry, 39(21), 1996, pp. 4135-4138
MECHANISTIC STUDIES OF THE 5-IODOURACIL CHROMOPHORE RELEVANT TO ITS USE IN NUCLEOPROTEIN PHOTO-CROSS-LINKING
Authors: NORRIS CL MEISENHEIMER PL KOCH TH
Citation: Cl. Norris et al., MECHANISTIC STUDIES OF THE 5-IODOURACIL CHROMOPHORE RELEVANT TO ITS USE IN NUCLEOPROTEIN PHOTO-CROSS-LINKING, Journal of the American Chemical Society, 118(24), 1996, pp. 5796-5803
USING IN-VITRO SELECTION TO DIRECT THE COVALENT ATTACHMENT OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REV PROTEIN TO HIGH-AFFINITY RNA LIGANDS
Authors: JENSEN KB ATKINSON BL WILLIS MC KOCH TH GOLD L
Citation: Kb. Jensen et al., USING IN-VITRO SELECTION TO DIRECT THE COVALENT ATTACHMENT OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REV PROTEIN TO HIGH-AFFINITY RNA LIGANDS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(26), 1995, pp. 12220-12224
DISPROPORTIONATION OF DIIRON NONACARBONYL IN TNF SOLUTION - FORMATIONAND STRUCTURE OF FE(THF)(4)[HFE3(CO)(11)](2)
Authors: BROOK DJR LYNCH V KOCH TH
Citation: Djr. Brook et al., DISPROPORTIONATION OF DIIRON NONACARBONYL IN TNF SOLUTION - FORMATIONAND STRUCTURE OF FE(THF)(4)[HFE3(CO)(11)](2), Inorganic chemistry, 34(22), 1995, pp. 5691
AN RNA-PROTEIN CONTACT DETERMINED BY 5-BROMOURIDINE SUBSTITUTION, PHOTO-CROSS-LINKING AND SEQUENCING
Authors: WILLIS MC LECUYER KA MEISENHEIMER KM UHLENBECK OC KOCH TH
Citation: Mc. Willis et al., AN RNA-PROTEIN CONTACT DETERMINED BY 5-BROMOURIDINE SUBSTITUTION, PHOTO-CROSS-LINKING AND SEQUENCING, Nucleic acids research, 22(23), 1994, pp. 4947-4952
TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE (VOL 33, PG 3364, 1994)
Authors: HICKE BJ WILLIS MC KOCH TH CECH TR
Citation: Bj. Hicke et al., TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE (VOL 33, PG 3364, 1994), Biochemistry, 33(24), 1994, pp. 7744-7744
TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE
Authors: HICKE BJ WILLIS MC KOCH TH CECH TR
Citation: Bj. Hicke et al., TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE, Biochemistry, 33(11), 1994, pp. 3364-3373
REACTION OF ANTHRACYCLINE ANTITUMOR DRUGS WITH REDUCED GLUTATHIONE - FORMATION OF AGLYCON CONJUGATES
Authors: GAUDIANO G RESING K KOCH TH
Citation: G. Gaudiano et al., REACTION OF ANTHRACYCLINE ANTITUMOR DRUGS WITH REDUCED GLUTATHIONE - FORMATION OF AGLYCON CONJUGATES, Journal of the American Chemical Society, 116(15), 1994, pp. 6537-6544
PHOTO-CROSS-LINKING OF 5-IODOURACIL SUBSTITUTED RNA AND DNA TO PROTEINS
Authors: WILLIS MC HICKE BJ UHLENBECK OC CECH TR KOCH TH
Citation: Mc. Willis et al., PHOTO-CROSS-LINKING OF 5-IODOURACIL SUBSTITUTED RNA AND DNA TO PROTEINS, Science, 262(5137), 1993, pp. 1255-1257
5-BIS(HYDROXYMETHYL)-3-METHYL-2-OXOMORPHOLIN-3-YL] (BHM-3 DIMER) - A LOW TOXICITY, WATER-SOLUBLE, ONE-ELECTRON REDUCING AGENT
Authors: GAUDIANO G FRANK E WYSOR MS AVERBUCH SD KOCH TH
Citation: G. Gaudiano et al., 5-BIS(HYDROXYMETHYL)-3-METHYL-2-OXOMORPHOLIN-3-YL] (BHM-3 DIMER) - A LOW TOXICITY, WATER-SOLUBLE, ONE-ELECTRON REDUCING AGENT, Journal of organic chemistry, 58(26), 1993, pp. 7355-7363
SYNTHESIS AND REDOX CHEMISTRY OF 5-DEOXYDAUNOMYCIN - A LONG-LIVED HYDROQUINONE TAUTOMER
Authors: SCHWEITZER BA KOCH TH
Citation: Ba. Schweitzer et Th. Koch, SYNTHESIS AND REDOX CHEMISTRY OF 5-DEOXYDAUNOMYCIN - A LONG-LIVED HYDROQUINONE TAUTOMER, Journal of the American Chemical Society, 115(13), 1993, pp. 5440-5445
GLYCOSIDIC CLEAVAGE FROM ANAEROBIC SAPONIFICATION OF THE HEPTAACETATEOF DAUNOMYCIN HYDROQUINONE
Authors: SCHWEITZER BA KOCH TH
Citation: Ba. Schweitzer et Th. Koch, GLYCOSIDIC CLEAVAGE FROM ANAEROBIC SAPONIFICATION OF THE HEPTAACETATEOF DAUNOMYCIN HYDROQUINONE, Journal of the American Chemical Society, 115(13), 1993, pp. 5446-5452
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