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Results: 1-25 | 26-42
Results: 1-25/42
FUNCTIONAL CAPABILITIES OF MOLECULAR NETWORK COMPONENTS CONTROLLING THE MAMMALIAN G1 S CELL-CYCLE PHASE-TRANSITION/
Authors: KOHN KW
Citation: Kw. Kohn, FUNCTIONAL CAPABILITIES OF MOLECULAR NETWORK COMPONENTS CONTROLLING THE MAMMALIAN G1 S CELL-CYCLE PHASE-TRANSITION/, Oncogene, 16(8), 1998, pp. 1065-1075
MOLECULAR MODELING STUDIES OF THE DNA-TOPOISOMERASE-I TERNARY CLEAVABLE COMPLEX WITH CAMPTOTHECIN
Authors: FAN Y WEINSTEIN JN KOHN KW SHI LM POMMIER Y
Citation: Y. Fan et al., MOLECULAR MODELING STUDIES OF THE DNA-TOPOISOMERASE-I TERNARY CLEAVABLE COMPLEX WITH CAMPTOTHECIN, Journal of medicinal chemistry, 41(13), 1998, pp. 2216-2226
INACTIVATION OF P53 INCREASES THE CYTOTOXICITY OF CAMPTOTHECIN IN HUMAN COLON HCT116 AND BREAST MCF-7 CANCER-CELLS
Authors: GUPTA M FAN SJ ZHAN QM KOHN KW OCONNOR PM POMMIER Y
Citation: M. Gupta et al., INACTIVATION OF P53 INCREASES THE CYTOTOXICITY OF CAMPTOTHECIN IN HUMAN COLON HCT116 AND BREAST MCF-7 CANCER-CELLS, Clinical cancer research, 3(9), 1997, pp. 1653-1660
FUNCTIONAL CAPABILITIES OF MOLECULAR NETWORK COMPONENTS CONTROLLING THE MAMMALIAN G1 S CELL-CYCLE PHASE-TRANSITION/
Authors: KOHN KW
Citation: Kw. Kohn, FUNCTIONAL CAPABILITIES OF MOLECULAR NETWORK COMPONENTS CONTROLLING THE MAMMALIAN G1 S CELL-CYCLE PHASE-TRANSITION/, Molecular biology of the cell, 8, 1997, pp. 96-96
AN INFORMATION-INTENSIVE APPROACH TO THE MOLECULAR PHARMACOLOGY OF CANCER
Authors: WEINSTEIN JN MYERS TG OCONNOR PM FRIEND SH FORNACE AJ KOHN KW FOJO T BATES SE RUBINSTEIN LV ANDERSON NL BUOLAMWINI JK VANOSDOL WW MONKS AP SCUDIERO DA SAUSVILLE EA ZAHAREVITZ DW BUNOW B VISWANADHAN VN JOHNSON GS WITTES RE PAULL KD
Citation: Jn. Weinstein et al., AN INFORMATION-INTENSIVE APPROACH TO THE MOLECULAR PHARMACOLOGY OF CANCER, Science, 275(5298), 1997, pp. 343-349
NOVEL 7-ALKYL METHYLENEDIOXY-CAMPTOTHECIN DERIVATIVES EXHIBIT INCREASED CYTOTOXICITY AND INDUCE PERSISTENT CLEAVABLE COMPLEXES BOTH WITH PURIFIED MAMMALIAN TOPOISOMERASE-I AND IN HUMAN COLON-CARCINOMA SW620 CELLS
Authors: VALENTI M NIEVESNEIRA W KOHLHAGEN G KOHN KW WALL ME WANI MC POMMIER Y
Citation: M. Valenti et al., NOVEL 7-ALKYL METHYLENEDIOXY-CAMPTOTHECIN DERIVATIVES EXHIBIT INCREASED CYTOTOXICITY AND INDUCE PERSISTENT CLEAVABLE COMPLEXES BOTH WITH PURIFIED MAMMALIAN TOPOISOMERASE-I AND IN HUMAN COLON-CARCINOMA SW620 CELLS, Molecular pharmacology, 52(1), 1997, pp. 82-87
EFFECTS OF URACIL INCORPORATION, DNA MISMATCHES, AND ABASIC SITES ON CLEAVAGE AND RELIGATION ACTIVITIES OF MAMMALIAN TOPOISOMERASE-I
Authors: POURQUIER P UENG LM KOHLHAGEN G MAZUMDER A GUPTA M KOHN KW POMMIER Y
Citation: P. Pourquier et al., EFFECTS OF URACIL INCORPORATION, DNA MISMATCHES, AND ABASIC SITES ON CLEAVAGE AND RELIGATION ACTIVITIES OF MAMMALIAN TOPOISOMERASE-I, The Journal of biological chemistry, 272(12), 1997, pp. 7792-7796
CHARACTERIZATION OF THE P53 TUMOR-SUPPRESSOR PATHWAY IN CELL-LINES OFTHE NATIONAL-CANCER-INSTITUTE ANTICANCER DRUG SCREEN AND CORRELATIONSWITH THE GROWTH-INHIBITORY POTENCY OF 123 ANTICANCER AGENTS
Authors: OCONNOR PM JACKMAN J BAE I MYERS TG FAN SJ MUTOH M SCUDIERO DA MONKS A SAUSVILLE EA WEINSTEIN JN FRIEND S FORNACE AJ KOHN KW
Citation: Pm. Oconnor et al., CHARACTERIZATION OF THE P53 TUMOR-SUPPRESSOR PATHWAY IN CELL-LINES OFTHE NATIONAL-CANCER-INSTITUTE ANTICANCER DRUG SCREEN AND CORRELATIONSWITH THE GROWTH-INHIBITORY POTENCY OF 123 ANTICANCER AGENTS, Cancer research, 57(19), 1997, pp. 4285-4300
ABROGATION OF AN S-PHASE CHECKPOINT AND POTENTIATION OF CAMPTOTHECIN CYTOTOXICITY BY 7-HYDROXYSTAUROSPORINE (UCN-O1) IN HUMAN CANCER CELL-LINES, POSSIBLY INFLUENCED BY P53 FUNCTION
Authors: SHAO RG CAO CX SHIMIZU T OCONNOR PM KOHN KW POMMIER Y
Citation: Rg. Shao et al., ABROGATION OF AN S-PHASE CHECKPOINT AND POTENTIATION OF CAMPTOTHECIN CYTOTOXICITY BY 7-HYDROXYSTAUROSPORINE (UCN-O1) IN HUMAN CANCER CELL-LINES, POSSIBLY INFLUENCED BY P53 FUNCTION, Cancer research, 57(18), 1997, pp. 4029-4035
REGULATORY GENES AND DRUG-SENSITIVITY
Authors: KOHN KW
Citation: Kw. Kohn, REGULATORY GENES AND DRUG-SENSITIVITY, Journal of the National Cancer Institute, 88(18), 1996, pp. 1255-1256
POTENTIATION OF CISPLATIN CYTOTOXICITY BY 9-AMINOCAMPTOTHECIN
Authors: GOLDWASSER F VALENTI M TORRES R KOHN KW POMMIER Y
Citation: F. Goldwasser et al., POTENTIATION OF CISPLATIN CYTOTOXICITY BY 9-AMINOCAMPTOTHECIN, Clinical cancer research, 2(4), 1996, pp. 687-693
APPLICATION OF THE ELECTROTOPOLOGICAL STATE INDEX TO QSAR ANALYSIS OFFLAVONE DERIVATIVES AS HIV-1 INTEGRASE INHIBITORS
Authors: BUOLAMWINI JK RAGHAVAN K FESEN MR POMMIER Y KOHN KW WEINSTEIN JN
Citation: Jk. Buolamwini et al., APPLICATION OF THE ELECTROTOPOLOGICAL STATE INDEX TO QSAR ANALYSIS OFFLAVONE DERIVATIVES AS HIV-1 INTEGRASE INHIBITORS, Pharmaceutical research, 13(12), 1996, pp. 1892-1895
DNA FILTER ELUTION - A WINDOW ON DNA-DAMAGE IN MAMMALIAN-CELLS
Authors: KOHN KW
Citation: Kw. Kohn, DNA FILTER ELUTION - A WINDOW ON DNA-DAMAGE IN MAMMALIAN-CELLS, BioEssays, 18(6), 1996, pp. 505-513
BEYOND DNA CROSS-LINKING - HISTORY AND PROSPECTS OF DNA-TARGETED CANCER-TREATMENT - 15TH BRUCE-F-CAIN-MEMORIAL-AWARD-LECTURE
Authors: KOHN KW
Citation: Kw. Kohn, BEYOND DNA CROSS-LINKING - HISTORY AND PROSPECTS OF DNA-TARGETED CANCER-TREATMENT - 15TH BRUCE-F-CAIN-MEMORIAL-AWARD-LECTURE, Cancer research, 56(24), 1996, pp. 5533-5546
CORRELATIONS BETWEEN S AND G(2) ARREST AND THE CYTOTOXICITY OF CAMPTOTHECIN IN HUMAN COLON-CARCINOMA CELLS
Authors: GOLDWASSER F SHIMIZU T JACKMAN J HOKI Y OCONNOR PM KOHN KW POMMIER Y
Citation: F. Goldwasser et al., CORRELATIONS BETWEEN S AND G(2) ARREST AND THE CYTOTOXICITY OF CAMPTOTHECIN IN HUMAN COLON-CARCINOMA CELLS, Cancer research, 56(19), 1996, pp. 4430-4437
DNA SEQUENCE-SELECTIVE AND STRUCTURE-SELECTIVE ALKYLATION OF GUANINE N2 IN THE DNA MINOR-GROOVE BY ECTEINASCIDIN-743, A POTENT ANTITUMOR COMPOUND FROM THE CARIBBEAN TUNICATE ECTEINASCIDIN-TURBINATA
Authors: POMMIER Y KOHLHAGEN G BAILLY C WARING M MAZUMDER A KOHN KW
Citation: Y. Pommier et al., DNA SEQUENCE-SELECTIVE AND STRUCTURE-SELECTIVE ALKYLATION OF GUANINE N2 IN THE DNA MINOR-GROOVE BY ECTEINASCIDIN-743, A POTENT ANTITUMOR COMPOUND FROM THE CARIBBEAN TUNICATE ECTEINASCIDIN-TURBINATA, Biochemistry, 35(41), 1996, pp. 13303-13309
DETECTION OF APOPTOSIS-ASSOCIATED DNA FRAGMENTATION USING A RAPID ANDQUANTITATIVE FILTER ELUTION ASSAY
Authors: BERTRAND R KOHN KW SOLARY E POMMIER Y
Citation: R. Bertrand et al., DETECTION OF APOPTOSIS-ASSOCIATED DNA FRAGMENTATION USING A RAPID ANDQUANTITATIVE FILTER ELUTION ASSAY, Drug development research, 34(2), 1995, pp. 138-144
INTERACTION OF AN ALKYLATING CAMPTOTHECIN DERIVATIVE WITH A DNA-BASE AT TOPOISOMERASE I-DNA CLEAVAGE SITES
Authors: POMMIER Y KOHLHAGEN G KOHN KW LETEURTRE F WANI MC WALL ME
Citation: Y. Pommier et al., INTERACTION OF AN ALKYLATING CAMPTOTHECIN DERIVATIVE WITH A DNA-BASE AT TOPOISOMERASE I-DNA CLEAVAGE SITES, Proceedings of the National Academy of Sciences of the United Statesof America, 92(19), 1995, pp. 8861-8865
3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP (QSAR) OF HIV INTEGRASE INHIBITORS - A COMPARATIVE MOLECULAR-FIELD ANALYSIS (COMFA) STUDY
Authors: RAGHAVAN K BUOLAMWINI JK FESEN MR POMMIER Y KOHN KW WEINSTEIN JN
Citation: K. Raghavan et al., 3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP (QSAR) OF HIV INTEGRASE INHIBITORS - A COMPARATIVE MOLECULAR-FIELD ANALYSIS (COMFA) STUDY, Journal of medicinal chemistry, 38(6), 1995, pp. 890-897
DISRUPTION OF P53 FUNCTION SENSITIZES BREAST-CANCER MCF-7 CELLS TO CISPLATIN AND PENTOXIFYLLINE
Authors: FAN SJ SMITH ML RIVET DJ DUBA D ZHAN QM KOHN KW FORNACE AJ OCONNOR PM
Citation: Sj. Fan et al., DISRUPTION OF P53 FUNCTION SENSITIZES BREAST-CANCER MCF-7 CELLS TO CISPLATIN AND PENTOXIFYLLINE, Cancer research, 55(8), 1995, pp. 1649-1654
UNSCHEDULED ACTIVATION OF CYCLIN B1 CDC2 KINASE IN HUMAN PROMYELOCYTIC LEUKEMIA-CELL LINE HL-60 CELLS UNDERGOING APOPTOSIS INDUCED BY DNA-DAMAGE/
Authors: SHIMIZU T OCONNOR PM KOHN KW POMMIER Y
Citation: T. Shimizu et al., UNSCHEDULED ACTIVATION OF CYCLIN B1 CDC2 KINASE IN HUMAN PROMYELOCYTIC LEUKEMIA-CELL LINE HL-60 CELLS UNDERGOING APOPTOSIS INDUCED BY DNA-DAMAGE/, Cancer research, 55(2), 1995, pp. 228-231
RELATIONSHIPS BETWEEN G(1) ARREST AND STABILITY OF THE P53 AND P21(CIP1 WAF1) PROTEINS FOLLOWING GAMMA-IRRADIATION OF HUMAN LYMPHOMA-CELLS/
Authors: BAE IS FAN SJ BHATIA K KOHN KW FORNACE AJ OCONNOR PM
Citation: Is. Bae et al., RELATIONSHIPS BETWEEN G(1) ARREST AND STABILITY OF THE P53 AND P21(CIP1 WAF1) PROTEINS FOLLOWING GAMMA-IRRADIATION OF HUMAN LYMPHOMA-CELLS/, Cancer research, 55(11), 1995, pp. 2387-2393
DIFFERENTIAL STABILIZATION OF EUKARYOTIC DNA TOPOISOMERASE-I CLEAVABLE COMPLEXES BY CAMPTOTHECIN DERIVATIVES
Authors: TANIZAWA A KOHN KW KOHLHAGEN G LETEURTRE F POMMIER Y
Citation: A. Tanizawa et al., DIFFERENTIAL STABILIZATION OF EUKARYOTIC DNA TOPOISOMERASE-I CLEAVABLE COMPLEXES BY CAMPTOTHECIN DERIVATIVES, Biochemistry, 34(21), 1995, pp. 7200-7206
INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE BY CURCUMIN
Authors: MAZUMDER A RAGHAVAN K WEINSTEIN J KOHN KW POMMIER Y
Citation: A. Mazumder et al., INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE BY CURCUMIN, Biochemical pharmacology, 49(8), 1995, pp. 1165-1170
USE OF THE KOHONEN SELF-ORGANIZING MAP TO STUDY THE MECHANISMS OF ACTION OF CHEMOTHERAPEUTIC-AGENTS
Authors: VANOSDOL WW MYERS TG PAULL KD KOHN KW WEINSTEIN JN
Citation: Ww. Vanosdol et al., USE OF THE KOHONEN SELF-ORGANIZING MAP TO STUDY THE MECHANISMS OF ACTION OF CHEMOTHERAPEUTIC-AGENTS, Journal of the National Cancer Institute, 86(24), 1994, pp. 1853-1859
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