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Results: 1-25/38
Authors:
Lombo, F
Pfeifer, B
Leaf, T
Ou, S
Kim, YS
Cane, DE
Licari, P
Khosla, C
Citation: F. Lombo et al., Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering, BIOTECH PR, 17(4), 2001, pp. 612-617
Structure-activity relationships within a family of selectively cytotoxic macrolide natural products
Authors:
Salomon, AR
Zhang, YB
Seto, H
Khosla, C
Citation: Ar. Salomon et al., Structure-activity relationships within a family of selectively cytotoxic macrolide natural products, ORG LETT, 3(1), 2001, pp. 57-59
Authors:
Pfeifer, BA
Khosla, C
Citation: Ba. Pfeifer et C. Khosla, Biosynthesis of polyketides in heterologous hosts, MICRO M B R, 65(1), 2001, pp. 106
Authors:
Salomon, AR
Voehringer, DW
Herzenberg, LA
Khosla, C
Citation: Ar. Salomon et al., Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase, CHEM BIOL, 8(1), 2001, pp. 71-80
Authors:
Yin, YF
Gokhale, R
Khosla, C
Cane, DE
Citation: Yf. Yin et al., Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase, BIOORG MED, 11(12), 2001, pp. 1477-1479
Authors:
Roberts, RJ
Varmus, HE
Ashburner, M
Brown, PO
Eisen, MB
Khosla, C
Kirschner, M
Nusse, R
Scott, M
Wold, B
Citation: Rj. Roberts et al., Information access - Building a "GenBank" of the published literature, SCIENCE, 291(5512), 2001, pp. 2318-2319
Authors:
Pfeifer, BA
Admiraal, SJ
Gramajo, H
Cane, DE
Khosla, C
Citation: Ba. Pfeifer et al., Biosynthesis of complex polyketides in a metabolically engineered strain of E-coli, SCIENCE, 291(5509), 2001, pp. 1790-1792
Authors:
Khosla, C
Harbury, PB
Citation: C. Khosla et Pb. Harbury, Modular enzymes, NATURE, 409(6817), 2001, pp. 247-252
Authors:
Chiu, HT
Hubbard, BK
Shah, AN
Eide, J
Fredenburg, RA
Walsh, CT
Khosla, C
Citation: Ht. Chiu et al., Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster, P NAS US, 98(15), 2001, pp. 8548-8553
Authors:
Tsuji, SY
Wu, N
Khosla, C
Citation: Sy. Tsuji et al., Intermodular communication in polyketide syntheses: Comparing the role of protein-protein interactions to those in other multidomain proteins, BIOCHEM, 40(8), 2001, pp. 2317-2325
Authors:
Tsuji, SY
Cane, DE
Khosla, C
Citation: Sy. Tsuji et al., Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules, BIOCHEM, 40(8), 2001, pp. 2326-2331
Authors:
Meadows, ES
Khosla, C
Citation: Es. Meadows et C. Khosla, In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase, BIOCHEM, 40(49), 2001, pp. 14855-14861
Authors:
Dreier, J
Li, Q
Khosla, C
Citation: J. Dreier et al., Malonyl-CoA : ACP transacylase from Streptomyces coelicolor has two alternative catalytically active nucleophiles, BIOCHEM, 40(41), 2001, pp. 12407-12411
Authors:
Admiraal, SJ
Walsh, CT
Khosla, C
Citation: Sj. Admiraal et al., The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates, BIOCHEM, 40(20), 2001, pp. 6116-6123
Authors:
Wu, N
Tsuji, SY
Cane, DE
Khosla, C
Citation: N. Wu et al., Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules, J AM CHEM S, 123(27), 2001, pp. 6465-6474
Authors:
Pohl, NL
Hans, M
Lee, HY
Kim, YS
Cane, DE
Khosla, C
Citation: Nl. Pohl et al., Remarkably broad substrate tolerance of Malonyl-CoA synthetase, an enzyme capable of intracellular synthesis of polyketide precursors, J AM CHEM S, 123(24), 2001, pp. 5822-5823
Authors:
Kinoshita, K
Williard, PG
Khosla, C
Cane, DE
Citation: K. Kinoshita et al., Precursor-directed biosynthesis of 16-membered macrolides by the erythromycin polyketide synthase, J AM CHEM S, 123(11), 2001, pp. 2495-2502
Authors:
Gokhale, RS
Khosla, C
Citation: Rs. Gokhale et C. Khosla, Role of linkers in communication between protein modules, CURR OP C B, 4(1), 2000, pp. 22-27
Authors:
Julien, B
Shah, S
Ziermann, R
Goldman, R
Katz, L
Khosla, C
Citation: B. Julien et al., Isolation and characterization of the epothilone biosynthetic gene clusterfrom Sorangium cellulosum, GENE, 249(1-2), 2000, pp. 153-160
Authors:
Khosla, C
Shivanna, KR
Ram, HYM
Citation: C. Khosla et al., Reproductive biology of Polypleurum stylosum (Podostemaceae), AQUATIC BOT, 67(2), 2000, pp. 143-154
Authors:
Hu, ZH
Hopwood, DA
Khosla, C
Citation: Zh. Hu et al., Directed transfer of large DNA fragments between Streptomyces species, APPL ENVIR, 66(5), 2000, pp. 2274-2277
Authors:
Burson, KK
Khosla, C
Citation: Kk. Burson et C. Khosla, Dissecting the chain length specificity in bacterial aromatic polyketide synthases using chimeric genes, TETRAHEDRON, 56(48), 2000, pp. 9401-9408
Authors:
Tang, L
Shah, S
Chung, L
Carney, J
Katz, L
Khosla, C
Julien, B
Citation: L. Tang et al., Cloning and heterologous expression of the epothilone gene cluster, SCIENCE, 287(5453), 2000, pp. 640-642
Authors:
Salomon, AR
Voehringer, DW
Herzenberg, LA
Khosla, C
Citation: Ar. Salomon et al., Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F0F1-ATPase, P NAS US, 97(26), 2000, pp. 14766-14771
Authors:
Khosla, C
Citation: C. Khosla, Natural product biosynthesis: A new interface between enzymology and medicine, J ORG CHEM, 65(24), 2000, pp. 8127-8133