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Results: 1-18 |
Results: 18

Authors: Kirn, D Martuza, RL Zwiebel, J
Citation: D. Kirn et al., Replication-selective virotherapy for cancer: Biological principles, risk management and future directions, NAT MED, 7(7), 2001, pp. 783-789

Authors: Ganly, I Kirn, D Eckhardt, SG Rodriguez, GI Soutar, DS Otto, R Robertson, AG Park, O Gulley, ML Heise, C VonHoff, DD Kaye, SB
Citation: I. Ganly et al., A phase I study of Onyx-015, an ELB-attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer (vol 6, pg 798, 2000), CLIN CANC R, 7(3), 2001, pp. 754-754

Authors: Mulvihlll, S Warren, R Venook, A Adler, A Randlev, B Heise, C Kirn, D
Citation: S. Mulvihlll et al., Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial, GENE THER, 8(4), 2001, pp. 308-315

Authors: Reid, T Galanis, E Abbruzzese, J Sze, D Andrews, J Romel, L Hatfield, M Rubin, J Kirn, D
Citation: T. Reid et al., Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase Itrial, GENE THER, 8(21), 2001, pp. 1618-1626

Authors: Kirn, D
Citation: D. Kirn, Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?, GENE THER, 8(2), 2001, pp. 89-98

Authors: Nemunaitis, J Cunningham, C Buchanan, A Blackburn, A Edelman, G Maples, P Netto, G Tong, A Randlev, B Olson, S Kirn, D
Citation: J. Nemunaitis et al., Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity, GENE THER, 8(10), 2001, pp. 746-759

Authors: Nemunaitis, J Khuri, F Ganly, I Arseneau, J Posner, M Vokes, E Kuhn, J McCarty, T Landers, S Blackburn, A Romel, L Randlev, B Kaye, S Kirn, D
Citation: J. Nemunaitis et al., Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer, J CL ONCOL, 19(2), 2001, pp. 289-298

Authors: Heise, C Hermiston, T Johnson, L Brooks, G Sampson-Johannes, A Williams, A Hawkins, L Kirn, D
Citation: C. Heise et al., An adenovirus E1A mutant that demonstrates potent and selective systemic antitumoral efficacy (vol 6, pg 1134, 2000), NAT MED, 6(12), 2000, pp. 1412-1412

Authors: Heise, C Hermiston, T Johnson, L Brooks, G Sampson-Johannes, A Williams, A Hawkins, L Kirn, D
Citation: C. Heise et al., An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy, NAT MED, 6(10), 2000, pp. 1134-1139

Authors: Ganly, I Kirn, D Eckhardt, SG Rodriguez, GI Soutar, DS Otto, R Robertson, AG Park, O Gulley, ML Heise, C VonHoff, DD Kaye, SB
Citation: I. Ganly et al., A Phase I study of Onyx-015, an E1B attenuated adenovirus, administered intramorally to patients with recurrent head and neck cancer (vol 6, pg 798, 2000), CLIN CANC R, 6(9), 2000, pp. 3797-3797

Authors: Ganly, I Kirn, D Eckhardt, SG Rodriguez, GI Soutar, DS Otto, R Robertson, AG Park, O Gulley, ML Heise, C Von Hoff, DD Kaye, SB
Citation: I. Ganly et al., A Phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer, CLIN CANC R, 6(3), 2000, pp. 798-806

Authors: Heise, C Lemmon, M Kirn, D
Citation: C. Heise et al., Efficacy with a replication-selective adenovirus plus cisplatin-based chemotherapy: Dependence on sequencing but not p53 functional status or route of administration, CLIN CANC R, 6(12), 2000, pp. 4908-4914

Authors: Heise, C Ganly, I Kim, YT Sampson-Johannes, A Brown, R Kirn, D
Citation: C. Heise et al., Efficacy of a replication-selective adenovirus against ovarian carcinomatosis is dependent on tumor burden, viral replication and p53 status, GENE THER, 7(22), 2000, pp. 1925-1929

Authors: Kirn, D
Citation: D. Kirn, Replication-selective oncolytic adenoviruses: virotherapy aimed at genetictargets in cancer, ONCOGENE, 19(56), 2000, pp. 6660-6669

Authors: Ahram, M Sameni, M Qiu, RG Linebaugh, B Kirn, D Sloane, BF
Citation: M. Ahram et al., Rac1-induced endocytosis is associated with intracellular proteolysis during migration through a three-dimensional matrix, EXP CELL RE, 260(2), 2000, pp. 292-303

Authors: Nemunaitis, J Ganly, I Khuri, F Arseneau, J Kuhn, J McCarty, T Landers, S Maples, P Romel, L Randlev, B Reid, T Kaye, S Kirn, D
Citation: J. Nemunaitis et al., Selective replication and oncolysis in p53 mutant tumors with ONYX-015, anE1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A Phase II trial, CANCER RES, 60(22), 2000, pp. 6359-6366

Authors: Kirn, D Hermiston, T
Citation: D. Kirn et T. Hermiston, Induction of an oncogenic fusion protein by a viral gene - a new chapter in an old story, NAT MED, 5(9), 1999, pp. 991-992

Authors: Kirn, D Hermiston, T McCormick, F
Citation: D. Kirn et al., ONYX-015: Clinical data are encouraging, NAT MED, 4(12), 1998, pp. 1341-1342
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