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Results: 1-25/27
Authors:
SPAHNLANGGUTH H
BAKTIR G
RADSCHUWEIT A
OKYAR A
TERHAAG B
ADER P
HANAFY A
LANGGUTH P
Citation: H. Spahnlangguth et al., P-GLYCOPROTEIN TRANSPORTERS AND THE GASTROINTESTINAL-TRACT - EVALUATION OF THE POTENTIAL IN-VIVO RELEVANCE OF IN-VITRO DATA EMPLOYING TALINOLOL AS MODEL-COMPOUND, International journal of clinical pharmacology and therapeutics, 36(1), 1998, pp. 16-24
Authors:
GIETZ U
ALDER R
LANGGUTH P
ARVINTE T
MERKLE HP
Citation: U. Gietz et al., CHEMICAL DEGRADATION KINETICS OF RECOMBINANT HIRUDIN (HV1) IN AQUEOUS-SOLUTION - EFFECT OF PH, Pharmaceutical research, 15(9), 1998, pp. 1456-1462
Authors:
DOPPENSCHMITT S
SPAHNLANGGUTH H
REGARDH CG
LANGGUTH P
Citation: S. Doppenschmitt et al., RADIOLIGAND-BINDING ASSAY EMPLOYING P-GLYCOPROTEIN-OVEREXPRESSING CELLS - TESTING DRUG AFFINITIES TO THE SECRETORY INTESTINAL MULTIDRUG TRANSPORTER, Pharmaceutical research, 15(7), 1998, pp. 1001-1006
Authors:
DRESSLER C
LANGGUTH P
ADER P
SPAHNLANGGUTH H
Citation: C. Dressler et al., LOSARTAN AND ITS ACTIVE METABOLITE EXP3174 - ESTIMATION OF PARTIAL CLEARANCES IN IN-VITRO AND IN-VIVO RAT STUDIES, Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 1998, pp. 11-11
Authors:
HANAFY A
LANGGUTH P
SPAHNLANGGUTH H
Citation: A. Hanafy et al., TISSUE DISTRIBUTION OF THE P-GLYCOPROTEIN SUBSTRATE TALINOLOL IN RATS- INFLUENCE OF VERAPAMIL, Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 1998, pp. 15-15
Authors:
HILGENDORF C
SPAHNLANGGUTH H
LANGGUTH P
Citation: C. Hilgendorf et al., CACO-2 AND HT29-MTX CELLS AND THEIR COCULTURES AS PERMEABILITY SCREENS FOR CARRIER-MEDIATED AND PASSIVE INTESTINAL TRANSPORT, Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 1998, pp. 16-16
Authors:
ANDERLE P
NIEDERER E
RUBAS W
HILGENDORF C
SPAHNLANGGUTH H
WUNDERLIALLENSPACH H
MERKLE HP
LANGGUTH P
Citation: P. Anderle et al., P-GLYCOPROTEIN (P-GP) MEDIATED EFFLUX IN CACO-2 CELL MONOLAYERS - THEINFLUENCE OF CULTURING CONDITIONS AND DRUG EXPOSURE ON P-GP EXPRESSION LEVELS, Journal of pharmaceutical sciences, 87(6), 1998, pp. 757-762
Authors:
LANGGUTH P
BOHNER V
HEIZMANN J
MERKLE HP
WOLFFRAM S
AMIDON GL
YAMASHITA S
Citation: P. Langguth et al., THE CHALLENGE OF PROTEOLYTIC-ENZYMES IN INTESTINAL PEPTIDE DELIVERY, Journal of controlled release, 46(1-2), 1997, pp. 39-57
Authors:
HERBER B
SPAHNLANGGUTH H
ROHRICH J
KAUERT G
LANGGUTH P
Citation: B. Herber et al., DISTRIBUTION OF IP AND NASAL COCAINE INTO THE CNS OF RATS - INCREASEDTISSUE-TO-BLOOD RATIOS AFTER APPLICATION ON THE NASAL-MUCOSA, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 4-4
Authors:
WEYHENMEYER R
KRUMBIEGEL G
LANG W
WACHTER W
LANGGUTH P
Citation: R. Weyhenmeyer et al., STUDIES ON THE INTESTINAL-ABSORPTION OF THE QUATERNARY TROSPIUM CHLORIDE FROM AQUEOUS-SOLUTION AND NOVEL FORMULATIONS, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 9-9
Authors:
DOPPENSCHMITT S
PORT R
LANGGUTH P
BALDAMUS CA
MUTSCHLER E
SPAHNLANGGUTH H
Citation: S. Doppenschmitt et al., PHARMACOKINETICS OF HYDROXYZINE AND ITS ACTIVE METABOLITE CETIRIZINE IN HEALTHY-VOLUNTEERS AND PATIENTS WITH RENAL-INSUFFICIENCY, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 453-453
Authors:
HILGENDORF C
SPAHNLANGGUTH H
LANGGUTH P
Citation: C. Hilgendorf et al., INTESTINAL SECRETION OF TALINOLOL - COMPETITIVE AND P-GP-ANTIBODY-INDUCED INHIBITION OF TRANSPORT IN STUDIES WITH CACO-2 CELLS, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 480-480
Authors:
LANG VB
LANGGUTH P
OTTIGER C
WUNDERLIALLENSPACH H
ROGNAN D
ROTHENRUTISHAUSER B
PERRIARD JC
LANG S
BIBER J
MERKLE HP
Citation: Vb. Lang et al., STRUCTURE-PERMEATION RELATIONS OF MET-ENKEPHALIN PEPTIDE ANALOGS ON ABSORPTION AND SECRETION MECHANISMS IN CACO-2 MONOLAYERS, Journal of pharmaceutical sciences, 86(7), 1997, pp. 846-853
Authors:
ADER P
GRENACHER B
LANGGUTH P
SCHARRER E
WOLFFRAM S
Citation: P. Ader et al., CINNAMATE UPTAKE BY RAT SMALL-INTESTINE - TRANSPORT KINETICS AND TRANSEPITHELIAL TRANSFER, Experimental physiology, 81(6), 1996, pp. 943-955
Authors:
WETTERICH U
SPAHNLANGGUTH H
MUTSCHLER E
TERHAAG B
ROSCH W
LANGGUTH P
Citation: U. Wetterich et al., EVIDENCE FOR INTESTINAL SECRETION AS AN ADDITIONAL CLEARANCE PATHWAY OF TALINOLOL ENANTIOMERS - CONCENTRATION-DEPENDENT AND DOSE-DEPENDENT ABSORPTION IN-VITRO AND IN-VIVO, Pharmaceutical research, 13(4), 1996, pp. 514-522
Authors:
LUESSEN HL
BOHNER V
PERARD D
LANGGUTH P
VERHOEF JC
DEBOER AG
MERKLE HP
JUNGINGER HE
Citation: Hl. Luessen et al., MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .5. EFFECT OF POLY(ACRYLATES) ON THE ENZYMATIC DEGRADATION OF PEPTIDE DRUGS BY INTESTINAL BRUSH-BORDER MEMBRANE-VESICLES, International journal of pharmaceutics, 141(1-2), 1996, pp. 39-52
Authors:
HEIZMANN J
LANGGUTH P
BIBER A
OSCHMANN R
MERKLE HP
WOLFFRAM S
Citation: J. Heizmann et al., ENZYMATIC CLEAVAGE OF THYMOPOIETIN OLIGOPEPTIDES BY PANCREATIC AND INTESTINAL BRUSH-BORDER ENZYMES, Peptides, 17(7), 1996, pp. 1083-1089
Authors:
LANG S
LANGGUTH P
OSCHMANN R
TRAVING B
MERKLE HP
Citation: S. Lang et al., TRANSPORT AND METABOLIC PATHWAY OF THYMOCARTIN (TP4) IN EXCISED BOVINE NASAL-MUCOSA, Journal of Pharmacy and Pharmacology, 48(11), 1996, pp. 1190-1196
Authors:
LIPKA E
LEE ID
LANGGUTH P
SPAHNLANGGUTH H
MUTSCHLER E
AMIDON GL
Citation: E. Lipka et al., CELIPROLOL DOUBLE-PEAK OCCURRENCE AND GASTRIC-MOTILITY - NONLINEAR MIXED EFFECTS MODELING OF BIOAVAILABILITY DATA OBTAINED IN DOGS, Journal of pharmacokinetics and biopharmaceutics, 23(3), 1995, pp. 267-286
Authors:
TAKI Y
SAKANE T
NADAI T
SEZAKI H
AMIDON GL
LANGGUTH P
YAMASHITA S
Citation: Y. Taki et al., GASTROINTESTINAL ABSORPTION OF PEPTIDE DRUG - QUANTITATIVE-EVALUATIONOF THE DEGRADATION AND THE PERMEATION OF METKEPHAMID IN RAT SMALL-INTESTINE, The Journal of pharmacology and experimental therapeutics, 274(1), 1995, pp. 373-377
Authors:
GIDO C
LANGGUTH P
MUTSCHLER E
Citation: C. Gido et al., PREDICTIONS OF IN-VIVO PLASMA-CONCENTRATIONS FROM IN-VITRO RELEASE KINETICS - APPLICATION TO DOXEPIN PARENTERAL (IM) SUSPENSIONS IN LIPOPHILIC VEHICLES IN DOGS, Pharmaceutical research, 11(6), 1994, pp. 800-808
Authors:
LANGGUTH P
MERKLE HP
AMIDON GL
Citation: P. Langguth et al., ORAL ABSORPTION OF PEPTIDES - THE EFFECT OF ABSORPTION SITE AND ENZYME-INHIBITION ON THE SYSTEMIC AVAILABILITY OF METKEPHAMID, Pharmaceutical research, 11(4), 1994, pp. 528-535
Authors:
LANGGUTH P
BREVES G
STOCKLI A
MERKLE HP
WOLFFRAM S
Citation: P. Langguth et al., COLONIC ABSORPTION AND BIOAVAILABILITY OF THE PENTAPEPTIDE METKEPHAMID IN THE RAT, Pharmaceutical research, 11(11), 1994, pp. 1640-1645
Authors:
LANGGUTH P
LEE KM
SPAHNLANGGUTH H
AMIDON GL
Citation: P. Langguth et al., VARIABLE GASTRIC-EMPTYING AND DISCONTINUITIES IN DRUG ABSORPTION PROFILES - DEPENDENCE OF RATES AND EXTENT OF CIMETIDINE ABSORPTION ON MOTILITY PHASE AND PH, Biopharmaceutics & drug disposition, 15(9), 1994, pp. 719-746
Authors:
LANGGUTH P
BOHNER V
BIBER J
MERKLE HP
Citation: P. Langguth et al., METABOLISM AND TRANSPORT OF THE PENTAPEPTIDE METKEPHAMID BY BRUSH-BORDER MEMBRANE-VESICLES OF RAT INTESTINE, Journal of Pharmacy and Pharmacology, 46(1), 1994, pp. 34-40