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METAANALYSIS OF STUDIES OF THE CYP2D6 POLYMORPHISM IN RELATION TO LUNG-CANCER AND PARKINSONS-DISEASE
Authors:
ROSTAMIHODJEGAN A
LENNARD MS
WOODS HE
TUCKER GT
Citation: A. Rostamihodjegan et al., METAANALYSIS OF STUDIES OF THE CYP2D6 POLYMORPHISM IN RELATION TO LUNG-CANCER AND PARKINSONS-DISEASE, Pharmacogenetics, 8(3), 1998, pp. 227-238
Authors:
SIMOOYA OO
SIJUMBILA G
LENNARD MS
TUCKER GT
Citation: Oo. Simooya et al., HALOFANTRINE AND CHLOROQUINE INHIBIT CYP2D6 ACTIVITY IN HEALTHY ZAMBIANS (VOL 45, PG 315, 1998), British journal of clinical pharmacology, 46(4), 1998, pp. 414-414
Authors:
SIMOOYA OO
SIJUMBIL G
LENNARD MS
TUCKER GT
Citation: Oo. Simooya et al., HALOFANTRINE AND CHLOROQUINE INHIBIT CYP2D6 ACTIVITY IN HEALTHY ZAMBIANS, British journal of clinical pharmacology, 45(3), 1998, pp. 315-317
Authors:
GHAHRAMANI P
ELLIS SW
LENNARD MS
RAMSAY LE
TUCKER GT
Citation: P. Ghahramani et al., CYTOCHROMES P450 MEDIATING THE N-DEMETHYLATION OF AMITRIPTYLINE, British journal of clinical pharmacology, 43(2), 1997, pp. 137-144
Authors:
LIN LY
DISTEFANO EW
SCHMITZ DA
HSU L
ELLIS SW
LENNARD MS
TUCKER GT
CHO AK
Citation: Ly. Lin et al., OXIDATION OF METHAMPHETAMINE AND METHYLENEDIOXYMETHAMPHETAMINE BY CYP2D6, Drug metabolism and disposition, 25(9), 1997, pp. 1059-1064
Authors:
LENNARD MS
CREWE HK
ELLIS SW
TUCKER GT
Citation: Ms. Lennard et al., THE 4-HYDROXYLATION OF TAMOXIFEN BY HUMAN LIVER CYTOCHROMES P450 2D6,2C9 AND 3A4, Clinical pharmacology and therapeutics, 61(2), 1997, pp. 37-37
Authors:
CREWE HK
ELLIS SW
LENNARD MS
TUCKER GT
Citation: Hk. Crewe et al., VARIABLE CONTRIBUTION OF CYTOCHROMES P450 2D6, 2C9 AND 3A4 TO THE 4-HYDROXYLATION OF TAMOXIFEN BY HUMAN LIVER-MICROSOMES, Biochemical pharmacology, 53(2), 1997, pp. 171-178
Authors:
GHAHRAMANI P
LENNARD MS
Citation: P. Ghahramani et Ms. Lennard, QUANTITATIVE-ANALYSIS OF AMITRIPTYLINE AND NORTRIPTYLINE IN HUMAN PLASMA AND LIVER MICROSOMAL PREPARATIONS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography B. Biomedical applications, 685(2), 1996, pp. 307-313
Authors:
JENNINGS M
SWEETLAND H
SMITH CAD
WOLF CR
LENNARD MS
TUCKER GT
WOODS HF
ROGERS K
Citation: M. Jennings et al., LACK OF RELATIONSHIPS BETWEEN THE DEBRISOQUINE (CYP2D6) AND MEPHENYTION (CYP2C19) OXIDATION POLYMORPHISMS AND SUSCEPTIBILITY TO BREAST-CANCER, Breast, 5(4), 1996, pp. 254-258
VARIABLE CONTRIBUTION OF CYP2D6 TO THE N-DEALKYLATION OF S-(-)-PROPRANOLOL BY HUMAN LIVER-MICROSOMES
Authors:
ROWLAND K
ELLIS SW
LENNARD MS
TUCKER GT
Citation: K. Rowland et al., VARIABLE CONTRIBUTION OF CYP2D6 TO THE N-DEALKYLATION OF S-(-)-PROPRANOLOL BY HUMAN LIVER-MICROSOMES, British journal of clinical pharmacology, 42(3), 1996, pp. 390-393
Authors:
ELLIS SW
ROWLAND K
ACKLAND MJ
REKKA E
SIMULA AP
LENNARD MS
WOLF CR
TUCKER GT
Citation: Sw. Ellis et al., INFLUENCE OF AMINO-ACID RESIDUE-374 OF CYTOCHROME-P-450 2D6 (CYP2D6) ON THE REGIO-SELECTIVE AND ENANTIO-SELECTIVE METABOLISM OF METOPROLOL, Biochemical journal, 316, 1996, pp. 647-654
Authors:
COLEMAN T
ELLIS SW
MARTIN IJ
LENNARD MS
TUCKER GT
Citation: T. Coleman et al., 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IS N-DEMETHYLATEDBY CYTOCHROMES P450 2D6, 1A2 AND 3A4 - IMPLICATIONS FOR SUSCEPTIBILITY TO PARKINSONS-DISEASE, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 685-690
Authors:
COE PL
LENNARD MS
TATLOW JC
Citation: Pl. Coe et al., CHLOROPOLYFLUORODIETHYL ETHERS, Journal of fluorine chemistry, 80(2), 1996, pp. 87-90
Authors:
COLEMAN T
ELLIS SW
MARTIN IJ
LENNARD MS
TUCKER GT
Citation: T. Coleman et al., MPTP IS N-DEMETHYLATED BY CYPS 2D6, 1A2 AND 3A4 - IMPLICATIONS FOR SUSCEPTIBILITY TO PARKINSONS-DISEASE, British Journal of Pharmacology, 117, 1996, pp. 127-127
Authors:
GARDNER IB
WALKER DK
LENNARD MS
SMITH DA
TUCKER GT
Citation: Ib. Gardner et al., COMPARISON OF THE DISPOSITION OF 2 NOVEL COMBINED THROMBOXANE SYNTHASE INHIBITORS THROMBAXANE-A(2) RECEPTOR ANTAGONISTS IN THE ISOLATED-PERFUSED RAT-LIVER, Xenobiotica, 25(2), 1995, pp. 185-197
Authors:
ELLIS SW
HAYHURST GP
SMITH G
LIGHTFOOT T
WONG MMS
SIMULA AP
ACKLAND MJ
STERNBERG MJE
LENNARD MS
TUCKER GT
WOLF CR
Citation: Sw. Ellis et al., EVIDENCE THAT ASPARTIC-ACID-301 IS A CRITICAL SUBSTRATE-CONTACT RESIDUE IN THE ACTIVE-SITE OF CYTOCHROME-P450 2D6, The Journal of biological chemistry, 270(49), 1995, pp. 29055-29058
Authors:
CHING MS
BLAKE CL
GHABRIAL H
ELLIS SW
LENNARD MS
TUCKER GT
SMALLWOOD RA
Citation: Ms. Ching et al., POTENT INHIBITION OF YEAST-EXPRESSED CYP2D6 BY DIHYDROQUINIDINE, QUINIDINE, AND ITS METABOLITES, Biochemical pharmacology, 50(6), 1995, pp. 833-837
Authors:
BULSARA D
ACKLAND MJ
DUNCAN JN
REES SA
ELLIS SW
LENNARD MS
TUCKER GT
Citation: D. Bulsara et al., EVALUATION OF A TEMPLATE MODEL OF THE CYP2D6 ACTIVE-SITE BY EXPERIMENTAL TESTING OF COMPOUNDS WITH RECOMBINANT HUMAN CYP2D6, The FASEB journal, 8(7), 1994, pp. 10001244-10001244
Authors:
WEERASURIYA K
JAYAKODY RL
SMITH CAD
WOLF CR
TUCKER GT
LENNARD MS
Citation: K. Weerasuriya et al., DEBRISOQUINE AND MEPHENYTOIN OXIDATION IN SINHALESE - A POPULATION STUDY, British journal of clinical pharmacology, 38(5), 1994, pp. 466-470
Authors:
ROWLAND K
YEO WW
ELLIS SW
CHADWICK IG
HAQ I
LENNARD MS
JACKSON PR
RAMSAY LE
TUCKER GT
Citation: K. Rowland et al., INHIBITION OF CYP2D6 ACTIVITY BY TREATMENT WITH PROPRANOLOL AND THE ROLE OF 4-HYDROXY PROPRANOLOL, British journal of clinical pharmacology, 38(1), 1994, pp. 9-14
Authors:
WILLIAMS ML
LENNARD MS
MARTIN IJ
TUCKER GT
Citation: Ml. Williams et al., INTERINDIVIDUAL VARIATION IN THE ISOMERIZATION OF 4-HYDROXYTAMOXIFEN BY HUMAN LIVER-MICROSOMES - INVOLVEMENT OF CYTOCHROMES P450, Carcinogenesis, 15(12), 1994, pp. 2733-2738
REGIOSELECTIVE AND ENANTIOSELECTIVE METABOLISM OF METOPROLOL BY 2 HUMAN CDNA-DERIVED CYP2D6 PROTEINS
Authors:
ELLIS SW
ROWLAND K
HARLOW JR
SIMULA AP
LENNARD MS
WOODS HF
TUCKER GT
WOLF CR
Citation: Sw. Ellis et al., REGIOSELECTIVE AND ENANTIOSELECTIVE METABOLISM OF METOPROLOL BY 2 HUMAN CDNA-DERIVED CYP2D6 PROTEINS, British Journal of Pharmacology, 112, 1994, pp. 210000124-210000124
Authors:
BARHAM HM
LENNARD MS
TUCKER GT
Citation: Hm. Barham et al., AN EVALUATION OF CYTOCHROME-P450 ISOFORM ACTIVITIES IN THE FEMALE DARK AGOUTI (DA) RAT - RELEVANCE TO ITS USE AS A MODEL OF THE CYP2D6 POORMETABOLIZER PHENOTYPE, Biochemical pharmacology, 47(8), 1994, pp. 1295-1307
Authors:
TUCKER GT
LENNARD MS
ELLIS SW
WOODS HF
CHO AK
LIN LY
HIRATSUKA A
SCHMITZ DA
CHU TYY
Citation: Gt. Tucker et al., THE DEMETHYLENATION OF METHYLENEDIOXYMETHAMPHETAMINE (ECSTASY) BY DEBRISOQUINE HYDROXYLASE (CYP2D6), Biochemical pharmacology, 47(7), 1994, pp. 1151-1156
Authors:
WATTS AR
LENNARD MS
MASON SL
TUCKER GT
WOODS HF
Citation: Ar. Watts et al., BEETURIA AND THE BIOLOGICAL FATE OF BEETROOT PIGMENTS, Pharmacogenetics, 3(6), 1993, pp. 302-311