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Results: 1-18 |
Results: 18
BIOPHYSICAL AND ANTISENSE PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 7-PROPYNYL-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, 7-IODO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES AND 7-CYANO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES
Authors: BALOW G MOHAN V LESNIK EA JOHNSTON JF MONIA BP ACEVEDO OL
Citation: G. Balow et al., BIOPHYSICAL AND ANTISENSE PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 7-PROPYNYL-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, 7-IODO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES AND 7-CYANO-7-DEAZA-2-AMINO-2'-DEOXYADENOSINES, Nucleic acids research, 26(14), 1998, pp. 3350-3357
WHAT AFFECTS THE EFFECT OF 2'-ALKOXY MODIFICATIONS - 1 - STABILIZATION EFFECT OF 2'-METHOXY SUBSTITUTIONS IN UNIFORMLY MODIFIED DNA OLIGONUCLEOTIDES
Authors: LESNIK EA FREIER SM
Citation: Ea. Lesnik et Sm. Freier, WHAT AFFECTS THE EFFECT OF 2'-ALKOXY MODIFICATIONS - 1 - STABILIZATION EFFECT OF 2'-METHOXY SUBSTITUTIONS IN UNIFORMLY MODIFIED DNA OLIGONUCLEOTIDES, Biochemistry, 37(19), 1998, pp. 6991-6997
EVALUATION OF PYRIMIDINE PNA BINDING TO SSDNA TARGETS FROM NONEQUILIBRIUM MELTING EXPERIMENTS
Authors: LESNIK EA RISEN LM DRIVER DA GRIFFITH MC SPRANKLE K FREIER SM
Citation: Ea. Lesnik et al., EVALUATION OF PYRIMIDINE PNA BINDING TO SSDNA TARGETS FROM NONEQUILIBRIUM MELTING EXPERIMENTS, Nucleic acids research, 25(3), 1997, pp. 568-574
2'-O-(2-METHOXY)ETHYL-MODIFIED ANTI-INTERCELLULAR ADHESION MOLECULE-1(ICAM-1) OLIGONUCLEOTIDES SELECTIVELY INCREASE THE ICAM-1 MESSENGER-RNA LEVEL AND INHIBIT FORMATION OF THE ICAM-1 TRANSLATION INITIATION COMPLEX IN HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS
Authors: BAKER BF LOT SS CONDON TP CHENGFLOURNOY S LESNIK EA SASMOR HM BENNETT CF
Citation: Bf. Baker et al., 2'-O-(2-METHOXY)ETHYL-MODIFIED ANTI-INTERCELLULAR ADHESION MOLECULE-1(ICAM-1) OLIGONUCLEOTIDES SELECTIVELY INCREASE THE ICAM-1 MESSENGER-RNA LEVEL AND INHIBIT FORMATION OF THE ICAM-1 TRANSLATION INITIATION COMPLEX IN HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS, The Journal of biological chemistry, 272(18), 1997, pp. 11994-12000
ENHANCED ACTIVITY OF AN ANTISENSE OLIGONUCLEOTIDE TARGETING MURINE PROTEIN-KINASE C-ALPHA BY THE INCORPORATION OF 2'-O-PROPYL MODIFICATIONS
Authors: MCKAY RA CUMMINS LL GRAHAM MJ LESNIK EA OWENS SR WINNIMAN M DEAN NM
Citation: Ra. Mckay et al., ENHANCED ACTIVITY OF AN ANTISENSE OLIGONUCLEOTIDE TARGETING MURINE PROTEIN-KINASE C-ALPHA BY THE INCORPORATION OF 2'-O-PROPYL MODIFICATIONS, Nucleic acids research, 24(3), 1996, pp. 411-417
INVESTIGATION OF SOME PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 4'-THIO-2'-DEOXYNUCLEOTIDES - DUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY
Authors: JONES GD LESNIK EA OWENS SR RISEN LM WALKER RT
Citation: Gd. Jones et al., INVESTIGATION OF SOME PROPERTIES OF OLIGODEOXYNUCLEOTIDES CONTAINING 4'-THIO-2'-DEOXYNUCLEOTIDES - DUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY, Nucleic acids research, 24(21), 1996, pp. 4117-4122
SEQUENCE-SPECIFIC ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE OLIGODEOXYRIBONUCLEOTIDE TARGETED TO HUMAN C-RAF KINASE SUPPORTS AN ANTISENSE MECHANISM OF ACTION IN-VIVO
Authors: MONIA BP SASMOR H JOHNSTON JF FREIER SM LESNIK EA MULLER M GEIGER T ALTMANN KH MOSER H FABBRO D
Citation: Bp. Monia et al., SEQUENCE-SPECIFIC ANTITUMOR-ACTIVITY OF A PHOSPHOROTHIOATE OLIGODEOXYRIBONUCLEOTIDE TARGETED TO HUMAN C-RAF KINASE SUPPORTS AN ANTISENSE MECHANISM OF ACTION IN-VIVO, Proceedings of the National Academy of Sciences of the United Statesof America, 93(26), 1996, pp. 15481-15484
MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY
Authors: FREIER SM BENNETT CF COOK PD CROOKE ST CUMMINS LL DEAN NM ECKER DJ GRIFFEY RH GUINOSSO CJ KORNBRUST D LEEDS J LESNIK EA MONIA BP SANGHVI YS ZUCKERMAN JE
Citation: Sm. Freier et al., MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY, Journal of cellular biochemistry, 1995, pp. 205-205
CHARACTERIZATION OF FULLY 2'-MODIFIED OLIGORIBONUCLEOTIDE HETERODUPLEX AND HOMODUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY
Authors: CUMMINS LL OWENS SR RISEN LM LESNIK EA FREIER SM MCGEE D GUINOSSO CJ COOK PD
Citation: Ll. Cummins et al., CHARACTERIZATION OF FULLY 2'-MODIFIED OLIGORIBONUCLEOTIDE HETERODUPLEX AND HOMODUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY, Nucleic acids research, 23(11), 1995, pp. 2019-2024
KINETIC CHARACTERISTICS OF ESCHERICHIA-COLI RNASE H1 - CLEAVAGE OF VARIOUS ANTISENSE OLIGONUCLEOTIDE-RNA DUPLEXES
Authors: CROOKE ST LEMONIDIS KM NEILSON L GRIFFEY R LESNIK EA MONIA BP
Citation: St. Crooke et al., KINETIC CHARACTERISTICS OF ESCHERICHIA-COLI RNASE H1 - CLEAVAGE OF VARIOUS ANTISENSE OLIGONUCLEOTIDE-RNA DUPLEXES, Biochemical journal, 312, 1995, pp. 599-608
RELATIVE THERMODYNAMIC STABILITY OF DNA, RNA, AND DNA-RNA HYBRID DUPLEXES - RELATIONSHIP WITH BASE COMPOSITION AND STRUCTURE
Authors: LESNIK EA FREIER SM
Citation: Ea. Lesnik et Sm. Freier, RELATIVE THERMODYNAMIC STABILITY OF DNA, RNA, AND DNA-RNA HYBRID DUPLEXES - RELATIONSHIP WITH BASE COMPOSITION AND STRUCTURE, Biochemistry, 34(34), 1995, pp. 10807-10815
SINGLE AND BIS PEPTIDE NUCLEIC-ACIDS AS TRIPLEXING AGENTS - BINDING AND STOICHIOMETRY
Authors: GRIFFITH MC RISEN LM GREIG MJ LESNIK EA SPRANKLE KG GRIFFEY RH KIELY JS FREIER SM
Citation: Mc. Griffith et al., SINGLE AND BIS PEPTIDE NUCLEIC-ACIDS AS TRIPLEXING AGENTS - BINDING AND STOICHIOMETRY, Journal of the American Chemical Society, 117(2), 1995, pp. 831-832
REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES
Authors: RAMASAMY KS ZOUNES M GONZALEZ C FREIER SM LESNIK EA CUMMINS LL GRIFFEY RH MONIA BP COOK PD
Citation: Ks. Ramasamy et al., REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES, Tetrahedron letters, 35(2), 1994, pp. 215-218
EFFECT OF 2'-SUBSTITUTION OF OLIGONUCLEOTIDES ON ANTISENSE INHIBITIONOF GENE-EXPRESSION
Authors: MONIA BP JOHNSTON JF CUMMINS LL OWENS SR RISEN LM LESNIK EA FREIER SM
Citation: Bp. Monia et al., EFFECT OF 2'-SUBSTITUTION OF OLIGONUCLEOTIDES ON ANTISENSE INHIBITIONOF GENE-EXPRESSION, Clinical chemistry, 40(12), 1994, pp. 2337-2337
TRITIUM LABELING OF ANTISENSE OLIGONUCLEOTIDES BY EXCHANGE WITH TRITIATED-WATER
Authors: GRAHAM MJ FREIER SM CROOKE RM ECKER DJ MASLOVA RN LESNIK EA
Citation: Mj. Graham et al., TRITIUM LABELING OF ANTISENSE OLIGONUCLEOTIDES BY EXCHANGE WITH TRITIATED-WATER, Nucleic acids research, 21(16), 1993, pp. 3737-3743
EVALUATION OF 2'-MODIFIED OLIGONUCLEOTIDES CONTAINING 2'-DEOXY GAPS AS ANTISENSE INHIBITORS OF GENE-EXPRESSION
Authors: MONIA BP LESNIK EA GONZALEZ C LIMA WF MCGEE D GUINOSSO CJ KAWASAKI AM COOK PD FREIER SM
Citation: Bp. Monia et al., EVALUATION OF 2'-MODIFIED OLIGONUCLEOTIDES CONTAINING 2'-DEOXY GAPS AS ANTISENSE INHIBITORS OF GENE-EXPRESSION, The Journal of biological chemistry, 268(19), 1993, pp. 14514-14522
OLIGODEOXYNUCLEOTIDES CONTAINING 2'-O-MODIFIED ADENOSINE - SYNTHESIS AND EFFECTS ON STABILITY OF DNA-RNA DUPLEXES
Authors: LESNIK EA GUINOSSO CJ KAWASAKI AM SASMOR H ZOUNES M CUMMINS LL ECKER DJ COOK PD FREIER SM
Citation: Ea. Lesnik et al., OLIGODEOXYNUCLEOTIDES CONTAINING 2'-O-MODIFIED ADENOSINE - SYNTHESIS AND EFFECTS ON STABILITY OF DNA-RNA DUPLEXES, Biochemistry, 32(30), 1993, pp. 7832-7838
CONFORMATIONAL CHARACTERISTICS OF THE HIGH-SALT FORM OF POLY(D2NH2A-DT) BASED ON H-1-]H-3 EXCHANGE BETWEEN WATER AND C8H GROUPS OF ITS ADENYLIC RESIDUES
Authors: LESNIK EA BESCHETNIKOVA ZA SAGI J MASLOVA RN VARSHAVSKII YM
Citation: Ea. Lesnik et al., CONFORMATIONAL CHARACTERISTICS OF THE HIGH-SALT FORM OF POLY(D2NH2A-DT) BASED ON H-1-]H-3 EXCHANGE BETWEEN WATER AND C8H GROUPS OF ITS ADENYLIC RESIDUES, Molecular biology, 26(5), 1992, pp. 753-755
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