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Results: 1-16 |
Results: 16
SEQUENCE-SPECIFIC MUTAGENESIS OF THE MAJOR (-ANTI-BENZO[A]PYRENE DIOLEPOXIDE DNA ADDUCT AT A MUTATIONAL HOT-SPOT IN-VITRO AND IN ESCHERICHIA-COLI-CELLS())
Authors: HANRAHAN CJ BACOLOD MD VYAS RR LIU TM GEACINTOV NE LOECHLER EL BASU AK
Citation: Cj. Hanrahan et al., SEQUENCE-SPECIFIC MUTAGENESIS OF THE MAJOR (-ANTI-BENZO[A]PYRENE DIOLEPOXIDE DNA ADDUCT AT A MUTATIONAL HOT-SPOT IN-VITRO AND IN ESCHERICHIA-COLI-CELLS()), Chemical research in toxicology, 10(4), 1997, pp. 369-377
MOLECULAR MODELING OF THE CONFORMATIONAL COMPLEXITY OF (-ANTI-B[A]PDE-ADDUCTED DNA USING SIMULATED ANNEALING())
Authors: KOZACK RE LOECHLER EL
Citation: Re. Kozack et El. Loechler, MOLECULAR MODELING OF THE CONFORMATIONAL COMPLEXITY OF (-ANTI-B[A]PDE-ADDUCTED DNA USING SIMULATED ANNEALING()), Carcinogenesis, 18(8), 1997, pp. 1585-1593
HOW STEREOCHEMISTRY AFFECTS MUTAGENESIS BY N-2-DEOXYGUANOSINE ADDUCTSOF Y-9,10-EPOXY-7,8,9,10-TETRAHYDROBENZO[ALPHA]PYRENE - CONFIGURATIONOF THE ADDUCT BOND IS MORE IMPORTANT THAN THOSE OF THE HYDROXYL-GROUPS
Authors: SHUKLA R JELINSKY S LIU TM GEACINTOV NE LOECHLER EL
Citation: R. Shukla et al., HOW STEREOCHEMISTRY AFFECTS MUTAGENESIS BY N-2-DEOXYGUANOSINE ADDUCTSOF Y-9,10-EPOXY-7,8,9,10-TETRAHYDROBENZO[ALPHA]PYRENE - CONFIGURATIONOF THE ADDUCT BOND IS MORE IMPORTANT THAN THOSE OF THE HYDROXYL-GROUPS, Biochemistry, 36(43), 1997, pp. 13263-13269
THE MAJOR, N-2-DG ADDUCT OF (-ANTI-B[A]PDE SHOWS A DRAMATICALLY DIFFERENT MUTAGENIC SPECIFICITY (PREDOMINANTLY, G-]A) IN A 5'-CGT-3' SEQUENCE CONTEXT())
Authors: SHUKLA R LIU TM GEACINTOV NE LOECHLER EL
Citation: R. Shukla et al., THE MAJOR, N-2-DG ADDUCT OF (-ANTI-B[A]PDE SHOWS A DRAMATICALLY DIFFERENT MUTAGENIC SPECIFICITY (PREDOMINANTLY, G-]A) IN A 5'-CGT-3' SEQUENCE CONTEXT()), Biochemistry, 36(33), 1997, pp. 10256-10261
EVIDENCE FOR A RECOMBINATION-INDEPENDENT PATHWAY FOR THE REPAIR OF DNA INTERSTRAND CROSS-LINKS BASED ON A SITE-SPECIFIC STUDY WITH NITROGEN-MUSTARD
Authors: BERARDINI M MACKAY W LOECHLER EL
Citation: M. Berardini et al., EVIDENCE FOR A RECOMBINATION-INDEPENDENT PATHWAY FOR THE REPAIR OF DNA INTERSTRAND CROSS-LINKS BASED ON A SITE-SPECIFIC STUDY WITH NITROGEN-MUSTARD, Biochemistry, 36(12), 1997, pp. 3506-3513
THE ROLE OF ADDUCT SITE-SPECIFIC MUTAGENESIS IN UNDERSTANDING HOW CARCINOGEN-DNA ADDUCTS CAUSE MUTATIONS - PERSPECTIVE, PROSPECTS AND PROBLEMS
Authors: LOECHLER EL
Citation: El. Loechler, THE ROLE OF ADDUCT SITE-SPECIFIC MUTAGENESIS IN UNDERSTANDING HOW CARCINOGEN-DNA ADDUCTS CAUSE MUTATIONS - PERSPECTIVE, PROSPECTS AND PROBLEMS, Carcinogenesis, 17(5), 1996, pp. 895-902
TARGETED A-]T AND G-]T MUTATIONS INDUCED BY SITE-SPECIFIC DEOXYADENOSINE AND DEOXYGUANOSINE ADDUCTS, RESPECTIVELY, FROM THE (-ANTI-DIOL EPOXIDE OF DIBENZ[AJ]ANTHRACENE IN M13MP7L2())
Authors: MIN Z GILL RD CORTEZ C HARVEY RG LOECHLER EL DIGIOVANNI J
Citation: Z. Min et al., TARGETED A-]T AND G-]T MUTATIONS INDUCED BY SITE-SPECIFIC DEOXYADENOSINE AND DEOXYGUANOSINE ADDUCTS, RESPECTIVELY, FROM THE (-ANTI-DIOL EPOXIDE OF DIBENZ[AJ]ANTHRACENE IN M13MP7L2()), Biochemistry, 35(13), 1996, pp. 4128-4138
HOW ARE POTENT BULKY CARCINOGENS ABLE TO INDUCE SUCH A DIVERSE ARRAY OF MUTATIONS
Authors: LOECHLER EL
Citation: El. Loechler, HOW ARE POTENT BULKY CARCINOGENS ABLE TO INDUCE SUCH A DIVERSE ARRAY OF MUTATIONS, Molecular carcinogenesis, 13(4), 1995, pp. 213-219
ARE BASE SUBSTITUTION AND FRAMESHIFT MUTAGENESIS PATHWAYS INTERRELATED - AN ANALYSIS BASED UPON STUDIES OF THE FREQUENCIES AND SPECIFICITIES OF MUTATIONS INDUCED BY THE (-ANTI DIOL EPOXIDE OF BENZO[A]PYRENE())
Authors: RODRIGUEZ H LOECHLER EL
Citation: H. Rodriguez et El. Loechler, ARE BASE SUBSTITUTION AND FRAMESHIFT MUTAGENESIS PATHWAYS INTERRELATED - AN ANALYSIS BASED UPON STUDIES OF THE FREQUENCIES AND SPECIFICITIES OF MUTATIONS INDUCED BY THE (-ANTI DIOL EPOXIDE OF BENZO[A]PYRENE()), Mutation research, 326(1), 1995, pp. 29-37
THE MAJOR, N-2-GUA ADDUCT OF THE (-ANTI-BENZO[A]PYRENE DIOL EPOXIDE CAN BE UNSTABLE IN DOUBLE-STRANDED DNA())
Authors: DROUIN EE LECH J LOECHLER EL
Citation: Ee. Drouin et al., THE MAJOR, N-2-GUA ADDUCT OF THE (-ANTI-BENZO[A]PYRENE DIOL EPOXIDE CAN BE UNSTABLE IN DOUBLE-STRANDED DNA()), Biochemistry, 34(7), 1995, pp. 2251-2259
THE MAJOR, N-2-GUA ADDUCT OF THE (-ANTI-BENZO[A]PYRENE DIOL EPOXIDE IS CAPABLE OF INDUCING G-]A AND G-]C, IN ADDITION TO G-]T, MUTATIONS())
Authors: JELINSKY SA LIU TM GEACINTOV NE LOECHLER EL
Citation: Sa. Jelinsky et al., THE MAJOR, N-2-GUA ADDUCT OF THE (-ANTI-BENZO[A]PYRENE DIOL EPOXIDE IS CAPABLE OF INDUCING G-]A AND G-]C, IN ADDITION TO G-]T, MUTATIONS()), Biochemistry, 34(41), 1995, pp. 13545-13553
A VIOLATION OF THE SWAIN-SCOTT PRINCIPLE, AND NOT S(N)1 VERSUS S(N)2 REACTION-MECHANISMS, EXPLAINS WHY CARCINOGENIC ALKYLATING-AGENTS CAN FORM DIFFERENT PROPORTIONS OF ADDUCTS AT OXYGEN VERSUS NITROGEN IN DNA
Authors: LOECHLER EL
Citation: El. Loechler, A VIOLATION OF THE SWAIN-SCOTT PRINCIPLE, AND NOT S(N)1 VERSUS S(N)2 REACTION-MECHANISMS, EXPLAINS WHY CARCINOGENIC ALKYLATING-AGENTS CAN FORM DIFFERENT PROPORTIONS OF ADDUCTS AT OXYGEN VERSUS NITROGEN IN DNA, Chemical research in toxicology, 7(3), 1994, pp. 277-280
MUTAGENIC SPECIFICITY OF THE (-DIOL EPOXIDE OF DIBENZ[A,J]ANTHRACENE IN THE SUPF GENE OF AN ESCHERICHIA-COLI PLASMID()ANTI)
Authors: GILL RD RODRIGUEZ H CORTEZ C HARVEY RG LOECHLER EL DIGIOVANNI J
Citation: Rd. Gill et al., MUTAGENIC SPECIFICITY OF THE (-DIOL EPOXIDE OF DIBENZ[A,J]ANTHRACENE IN THE SUPF GENE OF AN ESCHERICHIA-COLI PLASMID()ANTI), Molecular carcinogenesis, 8(3), 1993, pp. 145-154
CONSTRUCTION OF ESCHERICHIA-COLI VECTORS CONTAINING DEOXYADENOSINE AND DEOXYGUANOSINE ADDUCTS FROM (-ANTI-DIBENZ[A,J]ANTHRACENE DIOL EPOXIDE AT A DEFINED SITE())
Authors: GILL RD MIN Z CORTEZ C HARVEY RG LOECHLER EL DIGIOVANNI J
Citation: Rd. Gill et al., CONSTRUCTION OF ESCHERICHIA-COLI VECTORS CONTAINING DEOXYADENOSINE AND DEOXYGUANOSINE ADDUCTS FROM (-ANTI-DIBENZ[A,J]ANTHRACENE DIOL EPOXIDE AT A DEFINED SITE()), Chemical research in toxicology, 6(5), 1993, pp. 681-689
EVIDENCE FROM INVITRO REPLICATION THAT O6-METHYLGUANINE CAN ADOPT MULTIPLE CONFORMATIONS
Authors: DOSANJH MK LOECHLER EL SINGER B
Citation: Mk. Dosanjh et al., EVIDENCE FROM INVITRO REPLICATION THAT O6-METHYLGUANINE CAN ADOPT MULTIPLE CONFORMATIONS, Proceedings of the National Academy of Sciences of the United Statesof America, 90(9), 1993, pp. 3983-3987
AP SITES ARE NOT SIGNIFICANTLY INVOLVED IN MUTAGENESIS BY THE (-ANTI DIOL EPOXIDE OF BENZO[A]PYRENE - THE COMPLEXITY OF ITS MUTAGENIC SPECIFICITY IS LIKELY TO ARISE FROM ADDUCT CONFORMATIONAL POLYMORPHISM())
Authors: DROUIN EE LOECHLER EL
Citation: Ee. Drouin et El. Loechler, AP SITES ARE NOT SIGNIFICANTLY INVOLVED IN MUTAGENESIS BY THE (-ANTI DIOL EPOXIDE OF BENZO[A]PYRENE - THE COMPLEXITY OF ITS MUTAGENIC SPECIFICITY IS LIKELY TO ARISE FROM ADDUCT CONFORMATIONAL POLYMORPHISM()), Biochemistry, 32(26), 1993, pp. 6555-6562
Risultati: 1-16 |