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Results: 1-25/36
Authors:
Stad, R
Little, NA
Xirodimas, DP
Frenk, R
van der Eb, AJ
Lane, DP
Saville, MK
Jochemsen, AG
Citation: R. Stad et al., Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms, EMBO REP, 2(11), 2001, pp. 1029-1034
Authors:
Fischer, PM
Krausz, E
Lane, DP
Citation: Pm. Fischer et al., Cellular delivery of impermeable effector molecules in the form of conjugates with peptides capable of mediating membrane translocation, BIOCONJ CHE, 12(6), 2001, pp. 825-841
Authors:
Lipinski, KS
Djeha, AH
Krausz, E
Lane, DP
Searle, PF
Mountain, A
Wrighton, CJ
Citation: Ks. Lipinski et al., Tumour-specific therapeutic adenovirus vectors: repression of transgene expression in healthy cells by endogenous p53, GENE THER, 8(4), 2001, pp. 274-281
Authors:
Coates, PJ
Lorimore, SA
Rigat, BA
Lane, DP
Wright, EG
Citation: Pj. Coates et al., Induction of endogenous beta-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice, ONCOGENE, 20(48), 2001, pp. 7096-7097
Authors:
Xirodimas, D
Saville, MK
Edling, C
Lane, DP
Lain, S
Citation: D. Xirodimas et al., Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 invivo, ONCOGENE, 20(36), 2001, pp. 4972-4983
Authors:
Schumacher, U
Adam, E
Feldhaus, S
Katoh, M
Lane, DP
Citation: U. Schumacher et al., Cell differentiation and chemotherapy influence p53 and Mdm2 immunoreactivity in human HT29 colon cancer cells grown in scid mice, CANCER LETT, 166(2), 2001, pp. 215-221
Authors:
Liu, WL
Midgley, C
Stephen, C
Saville, M
Lane, DP
Citation: Wl. Liu et al., Biological significance of a small highly conserved region in the N terminus of the p53 tumour suppressor protein, J MOL BIOL, 313(4), 2001, pp. 711-731
Authors:
Xirodimas, DP
Stephen, CW
Lane, DP
Citation: Dp. Xirodimas et al., Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53, EXP CELL RE, 270(1), 2001, pp. 66-77
Authors:
Mattock, H
Lane, DP
Warbrick, E
Citation: H. Mattock et al., Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein, EXP CELL RE, 265(2), 2001, pp. 234-241
Authors:
Mattock, H
Jares, P
Zheleva, DI
Lane, DP
Warbrick, E
Blow, JC
Citation: H. Mattock et al., Use of peptides from p21 (Waf1/Cip1) to investigate PCNA function in Xenopus egg extracts, EXP CELL RE, 265(2), 2001, pp. 242-251
Authors:
Fischer, PM
Zhelev, NZ
Wang, S
Melville, JE
Fahraeus, R
Lane, DP
Citation: Pm. Fischer et al., Structure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin, J PEPT RES, 55(2), 2000, pp. 163-172
Authors:
Herbert, TP
Fahraeus, R
Prescott, A
Lane, DP
Proud, CG
Citation: Tp. Herbert et al., Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E, CURR BIOL, 10(13), 2000, pp. 793-796
Authors:
Steele, RJC
Lane, DP
Citation: Rjc. Steele et Dp. Lane, Gene therapy for gastric cancer: problems and prospects, SURG ONCOL, 9(1), 2000, pp. 13-16
Authors:
Midgley, CA
Desterro, JMP
Saville, MK
Howard, S
Sparks, A
Hay, RT
Lane, DP
Citation: Ca. Midgley et al., An N-terminal p14(ARF) peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo, ONCOGENE, 19(19), 2000, pp. 2312-2323
Authors:
Fischer, PM
Lane, DP
Citation: Pm. Fischer et Dp. Lane, Inhibitors of cyclin-dependent kinases as anti-cancer therapeutics, CURR MED CH, 7(12), 2000, pp. 1213-1245
Authors:
Paramio, JM
Segrelles, C
Lain, S
Gomez-Casero, E
Lane, DP
Lane, EB
Jorcano, JL
Citation: Jm. Paramio et al., p53 is phosphorylated at the carboxyl terminus and promotes the differentiation of human HaCaT keratinocytes, MOL CARCINO, 29(4), 2000, pp. 251-262
Authors:
Rodriguez, MS
Desterro, JMP
Lain, S
Lane, DP
Hay, RT
Citation: Ms. Rodriguez et al., Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation, MOL CELL B, 20(22), 2000, pp. 8458-8467
Authors:
Hupp, TR
Lane, DP
Ball, KL
Citation: Tr. Hupp et al., Strategies for manipulating the p53 pathway in the treatment of human cancer, BIOCHEM J, 352, 2000, pp. 1-17
Authors:
Ottaggio, L
Bozzo, S
Moro, F
Sparks, A
Campomenosi, P
Miele, M
Bonatti, S
Fronza, G
Lane, DP
Abbondandolo, A
Citation: L. Ottaggio et al., Defective nuclear localization of p53 protein in a Chinese hamster cell line is associated with the formation of stable cytoplasmic protein multimersin cells with gene amplification, CARCINOGENE, 21(9), 2000, pp. 1631-1638
Authors:
Hietanen, S
Lain, S
Krausz, E
Blattner, C
Lane, DP
Citation: S. Hietanen et al., Activation of p53 in cervical carcinoma cells by small molecules, P NAS US, 97(15), 2000, pp. 8501-8506
Authors:
Burch, LR
Midgley, CA
Currie, RA
Lane, DP
Hupp, TR
Citation: Lr. Burch et al., Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA, FEBS LETTER, 472(1), 2000, pp. 93-98
Authors:
Zheleva, DI
Zhelev, NZ
Fischer, PM
Duff, SV
Warbrick, E
Blake, DG
Lane, DP
Citation: Di. Zheleva et al., A quantitative study of the in vitro binding of the C-terminal domain of p21 to PCNA: Affinity, stoichiometry, and thermodynamics, BIOCHEM, 39(25), 2000, pp. 7388-7397
Authors:
Smart, P
Lane, EB
Lane, DP
Midgley, C
Vojtesek, B
Lain, S
Citation: P. Smart et al., Effects on normal fibroblasts and neuroblastoma cells of the activation ofthe p53 response by the nuclear export inhibitor leptomycin B, ONCOGENE, 18(51), 1999, pp. 7378-7386
Authors:
Bottger, V
Bottger, A
Garcia-Echeverria, C
Ramos, YFM
van der Eb, AJ
Jochemsen, AG
Lane, DP
Citation: V. Bottger et al., Comparative study of the p53-mdm2 and p53-MDMX interfaces, ONCOGENE, 18(1), 1999, pp. 189-199
Authors:
Fahraeus, R
Lane, DP
Citation: R. Fahraeus et Dp. Lane, The p16(INK4a) tumour suppressor protein inhibits alpha(v)beta(3) integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alpha(v)beta(3) to focal contacts, EMBO J, 18(8), 1999, pp. 2106-2118