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Results: 1-9 |
Results: 9
2-substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity
Authors: Kunick, C Schultz, C Lemcke, T Zaharevitz, DW Gussio, R Jalluri, RK Sausville, EA Leost, M Meijer, L
Citation: C. Kunick et al., 2-substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity, BIOORG MED, 10(6), 2000, pp. 567-569
Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition
Authors: Gussio, R Zaharevitz, DW McGrath, CF Pattabiraman, N Kellogg, GE Schultz, C Link, A Kunick, C Leost, M Meijer, L Sausville, EA
Citation: R. Gussio et al., Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition, ANTI-CAN DR, 15(1), 2000, pp. 53-66
Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex
Authors: Legraverend, M Tunnah, P Noble, M Ducrot, P Ludwig, O Grierson, DS Leost, M Meijer, L Endicott, J
Citation: M. Legraverend et al., Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex, J MED CHEM, 43(7), 2000, pp. 1282-1292
Paullones are potent inhibitors of glycogen synthase kinase-3 beta and cyclin-dependent kinase 5/p25
Authors: Leost, M Schultz, C Link, A Wu, YZ Biernat, J Mandelkow, EM Bibb, JA Snyder, GL Greengard, P Zaharevitz, DW Gussio, R Senderowicz, AM Sausville, EA Kunick, C Meijer, L
Citation: M. Leost et al., Paullones are potent inhibitors of glycogen synthase kinase-3 beta and cyclin-dependent kinase 5/p25, EUR J BIOCH, 267(19), 2000, pp. 5983-5994
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
Authors: Hoessel, R Leclerc, S Endicott, JA Nobel, MEM Lawrie, A Tunnah, P Leost, M Damiens, E Marie, D Marko, D Niederberger, E Tang, WC Eisenbrand, G Meijer, L
Citation: R. Hoessel et al., Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases, NAT CELL BI, 1(1), 1999, pp. 60-67
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors
Authors: Chang, YT Gray, NS Rosania, GR Sutherlin, DP Kwon, S Norman, TC Sarohia, R Leost, M Meijer, L Schultz, PG
Citation: Yt. Chang et al., Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors, CHEM BIOL, 6(6), 1999, pp. 361-375
Properties and potential applications of chemical inhibitors of cyclin-dependent kinases
Authors: Meijer, L Leclerc, S Leost, M
Citation: L. Meijer et al., Properties and potential applications of chemical inhibitors of cyclin-dependent kinases, PHARM THERA, 82(2-3), 1999, pp. 279-284
Paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity
Authors: Schultz, C Link, A Leost, M Zaharevitz, DW Gussio, R Sausville, EA Meijer, L Kunick, C
Citation: C. Schultz et al., Paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity, J MED CHEM, 42(15), 1999, pp. 2909-2919
Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases
Authors: Zaharevitz, DW Gussio, R Leost, M Senderowicz, AM Lahusen, T Kunick, C Meijer, L Sausville, EA
Citation: Dw. Zaharevitz et al., Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases, CANCER RES, 59(11), 1999, pp. 2566-2569
Risultati: 1-9 |