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Results: 1-25 | 26-37
Results: 1-25/37
Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones
Authors: Sinha, SC Sun, J Wartmann, M Lerner, RA
Citation: Sc. Sinha et al., Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones, CHEMBIOCHEM, 2(9), 2001, pp. 656-665
Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions
Authors: Tanaka, F Kerwin, L Kubitz, D Lerner, RA Barbas, CF
Citation: F. Tanaka et al., Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions, BIOORG MED, 11(22), 2001, pp. 2983-2986
Catalytic antibody route to the naturally occurring epothilones: Total synthesis of epothilones A-F
Authors: Sinha, SC Sun, J Miller, GP Wartmann, M Lerner, RA
Citation: Sc. Sinha et al., Catalytic antibody route to the naturally occurring epothilones: Total synthesis of epothilones A-F, CHEM-EUR J, 7(8), 2001, pp. 1691-1702
Antibody catalysis of the oxidation of water
Authors: Wentworth, P Jones, LH Wentworth, AD Zhu, XY Larsen, NA Wilson, IA Xu, X Goddard, WA Janda, KD Eschenmoser, A Lerner, RA
Citation: P. Wentworth et al., Antibody catalysis of the oxidation of water, SCIENCE, 293(5536), 2001, pp. 1806-1811
Synthesis of an organoinsulin molecule that can be activated by antibody catalysis
Authors: Worrall, DS McDunn, JE List, B Reichart, D Hevener, A Gustafson, T Barbas, CF Lerner, RA Olefsky, JM
Citation: Ds. Worrall et al., Synthesis of an organoinsulin molecule that can be activated by antibody catalysis, P NAS US, 98(24), 2001, pp. 13514-13518
In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy
Authors: Shabat, D Lode, HN Pertl, U Reisfeld, RA Rader, C Lerner, RA Barbas, CF
Citation: D. Shabat et al., In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy, P NAS US, 98(13), 2001, pp. 7528-7533
Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies
Authors: Chen, DW Beuscher, AE Stevens, RC Wirsching, P Lerner, RA Janda, KD
Citation: Dw. Chen et al., Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies, J ORG CHEM, 66(5), 2001, pp. 1725-1732
Structural basis for a disfavored elimination reaction in catalytic antibody 1D4
Authors: Larsen, NA Heine, A Crane, L Cravatt, BF Lerner, RA Wilson, IA
Citation: Na. Larsen et al., Structural basis for a disfavored elimination reaction in catalytic antibody 1D4, J MOL BIOL, 314(1), 2001, pp. 93-102
Conversion of enediynes into quinones by antibody catalysis and in aqueousbuffers: Implications for an alternative enediynes therapeutic mechanism
Authors: Jones, LH Harwig, CW Wentworth, P Simeonov, A Wentworth, AD Py, S Ashley, JA Lerner, RA Janda, KD
Citation: Lh. Jones et al., Conversion of enediynes into quinones by antibody catalysis and in aqueousbuffers: Implications for an alternative enediynes therapeutic mechanism, J AM CHEM S, 123(15), 2001, pp. 3607-3608
A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities
Authors: Hasserodt, J Janda, KD Lerner, RA
Citation: J. Hasserodt et al., A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities, BIO MED CH, 8(5), 2000, pp. 995-1003
An efficient benchtop system for multigram-scale kinetic resolutions usingaldolase antibodies
Authors: Turner, JM Bui, T Lerner, RA Barbas, CF List, B
Citation: Jm. Turner et al., An efficient benchtop system for multigram-scale kinetic resolutions usingaldolase antibodies, CHEM-EUR J, 6(15), 2000, pp. 2772-2774
In remembrance: Norton B. Gilula (1944-2000) - Obituary
Authors: Lerner, RA
Citation: Ra. Lerner, In remembrance: Norton B. Gilula (1944-2000) - Obituary, CELL, 103(4), 2000, pp. 541-542
Blue-fluorescent antibodies
Authors: Simeonov, A Matsushita, M Juban, EA Thompson, EHZ Hoffman, TZ Beuscher, AE Taylor, MJ Wirsching, P Rettig, W McCusker, JK Stevens, RC Millar, DP Schultz, PG Lerner, RA Janda, KD
Citation: A. Simeonov et al., Blue-fluorescent antibodies, SCIENCE, 290(5490), 2000, pp. 307-313
Mitotic misregulation and human aging
Authors: Ly, DH Lockhart, DJ Lerner, RA Schultz, PG
Citation: Dh. Ly et al., Mitotic misregulation and human aging, SCIENCE, 287(5462), 2000, pp. 2486-2492
Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task
Authors: Karlstrom, A Zhong, GF Rader, C Larsen, NA Heine, A Fuller, R List, B Tanaka, F Wilson, IA Barbas, CF Lerner, RA
Citation: A. Karlstrom et al., Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task, P NAS US, 97(8), 2000, pp. 3878-3883
Antibodies have the intrinsic capacity to destroy antigens
Authors: Wentworth, AD Jones, LH Wentworth, P Janda, KD Lerner, RA
Citation: Ad. Wentworth et al., Antibodies have the intrinsic capacity to destroy antigens, P NAS US, 97(20), 2000, pp. 10930-10935
Reconstructing aldolase antibodies to alter their substrate specificity and turnover
Authors: Tanaka, F Lerner, RA Barbas, CF
Citation: F. Tanaka et al., Reconstructing aldolase antibodies to alter their substrate specificity and turnover, J AM CHEM S, 122(19), 2000, pp. 4835-4836
Proline-catalyzed direct asymmetric aldol reactions
Authors: List, B Lerner, RA Barbas, CF
Citation: B. List et al., Proline-catalyzed direct asymmetric aldol reactions, J AM CHEM S, 122(10), 2000, pp. 2395-2396
Antibodies mimic natural oxidosqualene-cyclase action in steroid ring A formation
Authors: Hasserodt, J Janda, KD Lerner, RA
Citation: J. Hasserodt et al., Antibodies mimic natural oxidosqualene-cyclase action in steroid ring A formation, J AM CHEM S, 122(1), 2000, pp. 40-45
Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2. (vol 1, pg 59, 1999)
Authors: List, B Lerner, RA Barbas, CF
Citation: B. List et al., Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2. (vol 1, pg 59, 1999), ORG LETT, 1(2), 1999, pp. 353-353
Sets of aldolase antibodies with antipodal reactivities, formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol
Authors: Sinha, SC Sun, J Miller, G Barbas, CF Lerner, RA
Citation: Sc. Sinha et al., Sets of aldolase antibodies with antipodal reactivities, formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol, ORG LETT, 1(10), 1999, pp. 1623-1626
Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2
Authors: List, B Lerner, RA Barbas, CF
Citation: B. List et al., Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2, ORG LETT, 1(1), 1999, pp. 59-61
Broadening the aldolase catalytic antibody repertoire by combining reactive immunization and transition state theory: New enantio- and diastereoselectivities
Authors: Zhong, GF Lerner, RA Barbas, CF
Citation: Gf. Zhong et al., Broadening the aldolase catalytic antibody repertoire by combining reactive immunization and transition state theory: New enantio- and diastereoselectivities, ANGEW CHEM, 38(24), 1999, pp. 3738-3741
Convergence of catalytic antibody and terpene cyclase mechanisms: Polyene cyclization directed by carbocation - pi-interactions
Authors: Paschall, CM Hasserodt, J Jones, T Lerner, RA Janda, KD Christianson, DW
Citation: Cm. Paschall et al., Convergence of catalytic antibody and terpene cyclase mechanisms: Polyene cyclization directed by carbocation - pi-interactions, ANGEW CHEM, 38(12), 1999, pp. 1743-1747
Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy
Authors: Tanaka, F Lerner, RA Barbas, CF
Citation: F. Tanaka et al., Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy, CHEM COMMUN, (15), 1999, pp. 1383-1384
Risultati: 1-25 | 26-37