Authors:
DELLAPASCHOA OE
MANDEMA JW
VOSKUYL RA
DANHOF M
Citation: Oe. Dellapaschoa et al., PHARMACOKINETIC-PHARMACODYNAMIC MODELING OF THE ANTICONVULSANT AND ELECTROENCEPHALOGRAM EFFECTS OF PHENYTOIN IN RATS, The Journal of pharmacology and experimental therapeutics, 284(2), 1998, pp. 460-466
Citation: B. Tuk et al., RELEVANCE OF ARTERIOVENOUS CONCENTRATION DIFFERENCES IN PHARMACOKINETIC-PHARMACODYNAMIC MODELING OF MIDAZOLAM, The Journal of pharmacology and experimental therapeutics, 284(1), 1998, pp. 202-207
Citation: B. Tuk et al., THE IMPACT OF ARTERIOVENOUS CONCENTRATION DIFFERENCES ON PHARMACODYNAMIC PARAMETER ESTIMATES, Journal of pharmacokinetics and biopharmaceutics, 25(1), 1997, pp. 39-62
Citation: Cjjg. Bol et al., PHARMACOKINETIC-PHARMACODYNAMIC CHARACTERIZATION OF THE CARDIOVASCULAR, HYPNOTIC, EEG AND VENTILATORY RESPONSES TO DEXMEDETOMIDINE IN THE RAT, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1051-1058
Citation: Cjjg. Bol et al., DETERMINATION OF DEXMEDETOMIDINE IN RAT PLASMA BY A SENSITIVE [H-3] CLONIDINE RADIORECEPTOR ASSAY, Journal of pharmaceutical sciences, 86(7), 1997, pp. 822-826
Authors:
LOCKWOOD PA
MILLER R
MANDEMA JW
BUTLER J
DEVANE J
Citation: Pa. Lockwood et al., A PK PD MODEL FOR PAIN RELIEF (PR) FOLLOWING A SINGLE-DOSE OF 2 NSAIDFORMULATIONS WITH DIFFERENT IN-VIVO RELEASE RATES/, Clinical pharmacology and therapeutics, 61(2), 1997, pp. 70-70
Citation: Jw. Mandema, IMPACT OF FILL-IN SCHEMES FOR MISSING DATA IN ANALGESIC TRIALS ON PHARMACODYNAMIC (PD) PARAMETER ESTIMATES, Clinical pharmacology and therapeutics, 61(2), 1997, pp. 79-79
Authors:
MINTO CF
SCHNIDER TW
EGAN TD
YOUNGS E
LEMMENS HJM
GAMBUS PL
BILLARD V
HOKE JF
MOORE KHP
HERMANN DJ
MUIR KT
MANDEMA JW
SHAFER SL
Citation: Cf. Minto et al., INFLUENCE OF AGE AND GENDER ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF REMIFENTANIL .1. MODEL DEVELOPMENT, Anesthesiology, 86(1), 1997, pp. 10-23
Authors:
DOWRIE RH
EBLING WF
MANDEMA JW
STANSKI DR
Citation: Rh. Dowrie et al., HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY OF PROPOFOL IN HUMAN AND RAT PLASMA AND 14 RAT-TISSUES USING ELECTROCHEMICAL DETECTION, Journal of chromatography B. Biomedical applications, 678(2), 1996, pp. 279-288
Authors:
MANDEMA JW
KAIKO RF
OSHLACK B
REDER RF
STANSKI DR
Citation: Jw. Mandema et al., CHARACTERIZATION AND VALIDATION OF A PHARMACOKINETIC MODEL FOR CONTROLLED-RELEASE OXYCODONE, British journal of clinical pharmacology, 42(6), 1996, pp. 747-756
Authors:
HOOGERKAMP A
ARENDS RHGP
BOMERS AM
MANDEMA JW
VOSKUYL RA
DANHOF M
Citation: A. Hoogerkamp et al., PHARMACOKINETIC PHARMACODYNAMIC RELATIONSHIP OF BENZODIAZEPINES IN THE DIRECT CORTICAL STIMULATION MODEL OF ANTICONVULSANT EFFECT/, The Journal of pharmacology and experimental therapeutics, 279(2), 1996, pp. 803-812
Authors:
HARB GE
MANDEMA JW
DELAHUNTY T
BENOWITZ NB
COLEMAN R
SHEINER LB
JACOBSON MA
Citation: Ge. Harb et al., POPULATION PHARMACOKINETICS OF DIDANOSINE IN PATIENTS WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION, The Journal of infectious diseases, 173(1), 1996, pp. 273-273
Citation: Jw. Mandema et Dr. Stanski, POPULATION PHARMACODYNAMIC MODEL FOR KETOROLAC ANALGESIA, Clinical pharmacology and therapeutics, 60(6), 1996, pp. 619-635
Authors:
SCHNIDER TW
MINTO CF
BRUCKERT H
MANDEMA JW
Citation: Tw. Schnider et al., POPULATION PHARMACODYNAMIC MODELING AND COVARIATE DETECTION FOR CENTRAL NEURAL BLOCKADE, Anesthesiology, 85(3), 1996, pp. 502-512
Citation: C. Hoyovadillo et al., PHARMACODYNAMIC INTERACTION BETWEEN MIDAZOLAM AND A LOW-DOSE OF ETHANOL IN-VIVO, Life sciences, 57(4), 1995, pp. 325-333
Citation: Jw. Mandema et Dr. Wada, PHARMACODYNAMIC MODEL FOR ACUTE TOLERANCE DEVELOPMENT TO THE ELECTROENCEPHALOGRAPHIC EFFECTS OF ALFENTANIL IN THE RAT, The Journal of pharmacology and experimental therapeutics, 275(3), 1995, pp. 1185-1194
Authors:
MANDEMA JW
HU C
GAMBUS PL
BARR J
SHAFER SL
Citation: Jw. Mandema et al., POPULATION PHARMACODYNAMICS OF PROPOFOL FOR ICU SEDATION, Clinical pharmacology and therapeutics, 57(2), 1995, pp. 156-156
Authors:
MANDEMA JW
BROWN CR
MROSZCZAK EJ
TSINA IW
STANSKI DR
Citation: Jw. Mandema et al., POPULATION PHARMACODYNAMIC MODEL FOR KETOROLAC ANALGESIA, Clinical pharmacology and therapeutics, 57(2), 1995, pp. 188-188
Authors:
DELANGE ECM
BOUW MR
MANDEMA JW
DANHOF M
DEBEER AG
BREIMER DD
Citation: Ecm. Delange et al., APPLICATION OF INTRACEREBRAL MICRODIALYSIS TO STUDY REGIONAL DISTRIBUTION KINETICS OF DRUGS IN RAT-BRAIN, British Journal of Pharmacology, 116(5), 1995, pp. 2538-2544
Authors:
SCHNIDER TW
MINTO CF
BRUCKERT H
MANDEMA JW
Citation: Tw. Schnider et al., POPULATION PHARMACODYNAMIC MODELING AND COVARIATE DETECTION FOR CENTRAL NEURAL BLOCKADE, Anesthesiology, 83(3A), 1995, pp. 372-372
Authors:
KATARIA BK
VED SA
NICODEMUS HF
HOY GR
LEA D
DUBOIS MY
MANDEMA JW
SHAFER SL
Citation: Bk. Kataria et al., THE PHARMACOKINETICS OF PROPOFOL IN CHILDREN USING 3 DIFFERENT DATA-ANALYSIS APPROACHES, Anesthesiology, 80(1), 1994, pp. 104-122
Authors:
DANHOF M
MANDEMA JW
HOOGERKAMP A
MATHOT RAA
Citation: M. Danhof et al., PHARMACOKINETIC-PHARMACODYNAMIC MODELING IN PRECLINICAL INVESTIGATIONS - PRINCIPLES AND PERSPECTIVES, European journal of drug metabolism and pharmacokinetics, 18(1), 1993, pp. 41-47
Authors:
VANSTEVENINCK AL
MANDEMA JW
TUK B
VANDIJK JG
SCHOEMAKER HC
DANHOF M
COHEN AF
Citation: Al. Vansteveninck et al., A COMPARISON OF THE CONCENTRATION-EFFECT RELATIONSHIPS OF MIDAZOLAM FOR EEG-DERIVED PARAMETERS AND SACCADIC PEAK VELOCITY, British journal of clinical pharmacology, 36(2), 1993, pp. 109-115
Citation: Jw. Mandema et al., EFFECT OF EXPERIMENTAL LIVER AND KIDNEY DYSFUNCTION ON THE PHARMACO-KINETICS AND PHARMACODYNAMICS OF MIDAZOLAM IN THE RAT, Anesthesiology, 79(3A), 1993, pp. 10000363-10000363