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Results: 1-15 |
Results: 15
Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression
Authors: Stewart, AO Bhatia, PA McCarty, CM Patel, MV Staeger, MA Arendsen, DL Gunawardana, IW Melcher, LM Zhu, GD Boyd, SA Fry, DG Cool, BL Kifle, L Lartey, K Marsh, KC Kempf-Grote, AJ Kilgannon, P Wisdom, W Meyer, J Gallatin, WM Okasinski, GF
Citation: Ao. Stewart et al., Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression, J MED CHEM, 44(6), 2001, pp. 988-1002
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ETA antagonists
Authors: Jae, HS Winn, M von Geldern, TW Sorensen, BK Chiou, WJ Nguyen, B Marsh, KC Opgenorth, TJ
Citation: Hs. Jae et al., Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ETA antagonists, J MED CHEM, 44(23), 2001, pp. 3978-3984
Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides
Authors: Zhu, GD Arendsen, DL Gunawardana, IW Boyd, SA Stewart, AO Fry, DG Cool, BL Kifle, L Shaefer, V Meuth, J Marsh, KC Kempf-Grote, AJ Kilgannon, P Gallatin, WM Okasinski, GF
Citation: Gd. Zhu et al., Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides, J MED CHEM, 44(21), 2001, pp. 3469-3487
Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides
Authors: Pei, ZH Xin, ZL Liu, G Li, YH Reilly, EB Lubbers, NL Huth, JR Link, JT von Geldern, TW Cox, BF Leitza, S Gao, Y Marsh, KC DeVries, P Okasinski, GF
Citation: Zh. Pei et al., Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides, J MED CHEM, 44(18), 2001, pp. 2913-2920
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead
Authors: Liu, G Link, JT Pei, ZH Reilly, EB Leitza, S Nguyen, B Marsh, KC Okasinski, GF von Geldern, TW Ormes, M Fowler, K Gallatin, M
Citation: G. Liu et al., Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead, J MED CHEM, 43(21), 2000, pp. 4025-4040
3,5-bis(trifluoromethyl)pyrazoles: A novel class of NFAT transcription factor regulator
Authors: Djuric, SW BaMaung, NY Basha, A Liu, HQ Luly, JR Madar, DJ Sciotti, RJ Tu, NP Wagenaar, FL Wiedeman, PE Zhou, X Ballaron, S Bauch, J Chen, YW Chiou, XG Fey, T Gauvin, D Gubbins, E Hsieh, GC Marsh, KC Mollison, KW Pong, M Shaughnessy, TK Sheets, MP Smith, M Trevillyan, JM Warrior, U Wegner, CD Carter, GW
Citation: Sw. Djuric et al., 3,5-bis(trifluoromethyl)pyrazoles: A novel class of NFAT transcription factor regulator, J MED CHEM, 43(16), 2000, pp. 2975-2981
Quantitation of a new macrolide in plasma by high performance liquid chromatography with tandem mass spectrometric detection: Comparison with electrochemical detection
Authors: Daszkowski, DJ Ong, VS Menacherry, S El-Shourbagy, T Carroll, SL Marsh, KC
Citation: Dj. Daszkowski et al., Quantitation of a new macrolide in plasma by high performance liquid chromatography with tandem mass spectrometric detection: Comparison with electrochemical detection, J LIQ CHR R, 22(5), 1999, pp. 641-657
Discovery of a series of pyrrolidine-based endothelin receptor antagonistswith enhanced ETA receptor selectivity
Authors: Boyd, SA Mantei, RA Tasker, AS Liu, G Sorensen, BK Henry, KJ von Geldern, TW Winn, M Wu-Wong, JSR Chiou, WJ Dixon, DB Hutchins, CW Marsh, KC Nguyen, E Opgenorth, TJ
Citation: Sa. Boyd et al., Discovery of a series of pyrrolidine-based endothelin receptor antagonistswith enhanced ETA receptor selectivity, BIO MED CH, 7(6), 1999, pp. 991-1002
Pulmonary delivery of a dopamine D-1 agonist, ABT-431, in dogs and humans
Authors: Zheng, YQ Marsh, KC Bertz, RJ El-Shourbagy, T Adjei, AL
Citation: Yq. Zheng et al., Pulmonary delivery of a dopamine D-1 agonist, ABT-431, in dogs and humans, INT J PHARM, 191(2), 1999, pp. 131-140
Parenteral sustained-release dosage forms of butorphanol for dogs
Authors: Chang, HC Li, LC Marsh, KC Tian, Y Grischeau, D
Citation: Hc. Chang et al., Parenteral sustained-release dosage forms of butorphanol for dogs, INT J PHARM, 176(2), 1999, pp. 147-156
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ETB selectivity
Authors: von Geldern, TW Tasker, AS Sorensen, BK Winn, M Szczepankiewicz, BG Dixon, DB Chiou, WJ Wang, LM Wessale, JL Adler, A Marsh, KC Nguyen, E Opgenorth, TJ
Citation: Tw. Von Geldern et al., Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ETB selectivity, J MED CHEM, 42(18), 1999, pp. 3668-3678
Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ETB antagonists containing a diphenylmethylamine acetamide side chain
Authors: Liu, G Kozmina, NS Winn, M von Geldern, TW Chiou, WJ Dixon, DB Nguyen, E Marsh, KC Opgenorth, TJ
Citation: G. Liu et al., Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ETB antagonists containing a diphenylmethylamine acetamide side chain, J MED CHEM, 42(18), 1999, pp. 3679-3689
Pharmacology of A-216546: a highly selective antagonist for endothelin ETAreceptor
Authors: Wu-Wong, JSR Dixon, DB Chiou, WJ Dayton, BD Novosad, EI Adler, AL Wessale, JL Calzadilla, SV Hernandez, L Marsh, KC Liu, G Szczepankiewicz, B von Geldern, TW Opgenorth, TJ
Citation: Jsr. Wu-wong et al., Pharmacology of A-216546: a highly selective antagonist for endothelin ETAreceptor, EUR J PHARM, 366(2-3), 1999, pp. 189-201
Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P-3 ligands
Authors: Chen, XQ Kempf, DJ Sham, HL Green, BE Molla, A Korneyeva, M Vasavanonda, S Wideburg, NE Saldivar, A Marsh, KC McDonald, E Norbeck, DW
Citation: Xq. Chen et al., Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P-3 ligands, BIOORG MED, 8(24), 1998, pp. 3531-3536
ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease
Authors: Sham, HL Kempf, DJ Molla, A Marsh, KC Kumar, GN Chen, CM Kati, W Stewart, K Lal, R Hsu, A Betebenner, D Korneyeva, M Vasavanonda, S McDonald, E Saldivar, A Wideburg, N Chen, XQ Niu, P Park, C Jayanti, V Grabowski, B Granneman, GR Sun, E Japour, AJ Leonard, JM Plattner, JJ Norbeck, DW
Citation: Hl. Sham et al., ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease, ANTIM AG CH, 42(12), 1998, pp. 3218-3224
Risultati: 1-15 |