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Results: 1-25/27
Authors:
Roush, WR
Cheng, JM
Knapp-Reed, B
Alvarez-Hernandez, A
McKerrow, JH
Hansell, E
Engel, JC
Citation: Wr. Roush et al., Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain, BIOORG MED, 11(20), 2001, pp. 2759-2762
Authors:
Davies, SJ
Grogan, JL
Blank, RB
Lim, KC
Locksley, RM
McKerrow, JH
Citation: Sj. Davies et al., Modulation of blood fluke development in the liver by hepatic CD4(+) lymphocytes, SCIENCE, 294(5545), 2001, pp. 1358-1361
Authors:
Paddock, CD
McKerrow, JH
Hansell, E
Foreman, KW
Hsieh, I
Marshall, N
Citation: Cd. Paddock et al., Identification, cloning, and recombinant expression of procalin, a major triatomine allergen, J IMMUNOL, 167(5), 2001, pp. 2694-2699
Authors:
Lecaille, F
Cotton, J
McKerrow, JH
Ferrer-Di Martino, M
Boll-Bataille, E
Gauthier, F
Lalmanach, G
Citation: F. Lecaille et al., Reversible inhibition of cathepsin L-like proteases by 4-mer pseudopeptides, FEBS LETTER, 507(3), 2001, pp. 362-366
Authors:
Troeberg, L
Chen, XW
Flaherty, TM
Morty, RE
Cheng, MS
Hua, HM
Springer, C
McKerrow, JH
Kenyon, GL
Lonsdale-Eccles, JD
Coetzer, THT
Cohen, FE
Citation: L. Troeberg et al., Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei, MOL MED, 6(8), 2000, pp. 660-669
Authors:
McKerrow, JH
Bhargava, V
Hansell, E
Huling, S
Kuwahara, T
Matley, M
Coussens, L
Warren, R
Citation: Jh. Mckerrow et al., A functional proteomics screen of proteases in colorectal carcinoma, MOL MED, 6(5), 2000, pp. 450-460
Authors:
Du, XH
Hansell, E
Engel, JC
Caffrey, CR
Cohen, FE
McKerrow, JH
Citation: Xh. Du et al., Aryl ureas represent a new class of anti-trypanosomal agents, CHEM BIOL, 7(9), 2000, pp. 733-742
Authors:
Brinen, LS
Hansell, E
Cheng, JM
Roush, WR
McKerrow, JH
Fletterick, RJ
Citation: Ls. Brinen et al., A target within the target: probing Cruzain's P1 ' site to define structural determinants for the Chagas' disease protease, STRUCT F D, 8(8), 2000, pp. 831-840
Authors:
Brinen, LS
Que, XC
McKerrow, JH
Reed, SL
Citation: Ls. Brinen et al., Homology modeling of Entamoeba histolytica cysteine proteinases reveals the basis for cathepsin L-like structure with cathepsin B-like specificity, ARCH MED R, 31(4), 2000, pp. S63-S64
Authors:
Roush, WR
Hernandez, AA
McKerrow, JH
Selzer, PM
Hansell, E
Engel, JC
Citation: Wr. Roush et al., Design, synthesis and evaluation of D-homophenylalanyl epoxysuccinate inhibitors of the trypanosomal cysteine protease cruzain, TETRAHEDRON, 56(50), 2000, pp. 9747-9762
Authors:
Engel, JC
Garcia, CT
Hsieh, I
Doyle, PS
McKerrow, JH
Citation: Jc. Engel et al., Upregulation of the secretory pathway in cysteine protease inhibitor-resistant Trypanosoma cruzi, J CELL SCI, 113(8), 2000, pp. 1345-1354
Authors:
Engel, JC
Garcia, CT
Hsieh, I
Doyle, PS
McKerrow, JH
Citation: Jc. Engel et al., Upregulation of the secretory pathway in cysteine protease inhibitor-resistant Trypanosoma cruzi (vol 113, pg 1345, 2000), J CELL SCI, 113(14), 2000, pp. NIL_3-NIL_3
Authors:
Salter, JP
Lim, KC
Hansell, E
Hsieh, I
McKerrow, JH
Citation: Jp. Salter et al., Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease, J BIOL CHEM, 275(49), 2000, pp. 38667-38673
Authors:
Stoka, V
Turk, B
McKerrow, JH
Bjork, I
Cazzulo, JJ
Turk, V
Citation: V. Stoka et al., The high stability of cruzipain against pH-induced inactivation is not dependent on its C-terminal domain, FEBS LETTER, 469(1), 2000, pp. 29-32
Authors:
Caffrey, CR
Mathieu, MA
Gaffney, AM
Salter, JP
Sajid, M
Lucas, KD
Franklin, C
Bogyo, M
McKerrow, JH
Citation: Cr. Caffrey et al., Identification of a cDNA encoding an active asparaginyl endopeptidase of Schistosoma mansoni and its expression in Pichia pastoris, FEBS LETTER, 466(2-3), 2000, pp. 244-248
Authors:
Davies, SJ
McKerrow, JH
Citation: Sj. Davies et Jh. Mckerrow, Molecular mechanisms of granuloma formation in schistosomiasis, BIOLOGY OF PARASITISM, 2000, pp. 273-289
Authors:
McKerrow, JH
Engel, JC
Caffrey, CR
Citation: Jh. Mckerrow et al., Cysteine protease inhibitors as chemotherapy for parasitic infections, BIO MED CH, 7(4), 1999, pp. 639-644
Authors:
Chan, VJ
Selzer, PM
McKerrow, JH
Sakanari, JA
Citation: Vj. Chan et al., Expression and alteration of the S-2 subsite of the Leishmania major cathepsin B-like cysteine protease, BIOCHEM J, 340, 1999, pp. 113-117
Authors:
McKerrow, JH
Huima, T
Lustigman, S
Citation: Jh. Mckerrow et al., Do filarid nematodes have a vascular system?, PARASIT TOD, 15(3), 1999, pp. 123-123
Authors:
Britton, C
Redmond, DL
Knox, DP
McKerrow, JH
Barry, JD
Citation: C. Britton et al., Identification of promoter elements of parasite nematode genes in transgenic Caenorhabditis elegans, MOL BIOCH P, 103(2), 1999, pp. 171-181
Authors:
Selzer, PM
Pingel, S
Hsieh, I
Ugele, B
Chan, VJ
Engel, JC
Bogyo, M
Russell, DG
Sakanari, JA
McKerrow, JH
Citation: Pm. Selzer et al., Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target, P NAS US, 96(20), 1999, pp. 11015-11022
Authors:
Engel, JC
Doyle, PS
McKerrow, JH
Citation: Jc. Engel et al., Trypanocidal effect of cysteine protease inhibitors in vitro and in vivo in experimental Chagas disease, MEDICINA, 59, 1999, pp. 171-175
Authors:
Huete-Perez, JA
Engel, JC
Brinen, LS
Mottram, JC
McKerrow, JH
Citation: Ja. Huete-perez et al., Protease trafficking in two primitive eukaryotes is mediated by a prodomain protein motif, J BIOL CHEM, 274(23), 1999, pp. 16249-16256
Authors:
McKerrow, JH
Citation: Jh. Mckerrow, Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action, INT J PARAS, 29(6), 1999, pp. 833-837
Authors:
Troeberg, L
Morty, RE
Pike, RN
Lonsdale-Eccles, JD
Palmer, JT
McKerrow, JH
Coetzer, THT
Citation: L. Troeberg et al., Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei, EXP PARASIT, 91(4), 1999, pp. 349-355