Authors:
Suri, S
Monkkonen, J
Taskinen, M
Pesonen, J
Blank, MA
Phipps, RJ
Rogers, MJ
Citation: S. Suri et al., Nitrogen-containing bisphosphonates induce apoptosis of Caco-2 cells in vitro by inhibiting the mevalonate pathway: A model of bisphosphonate-inducedgastrointestinal toxicity, BONE, 29(4), 2001, pp. 336-343
Authors:
Raiman, J
Niemi, R
Vepsalainen, J
Yritys, K
Jarvinen, T
Monkkonen, J
Citation: J. Raiman et al., Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells, INT J PHARM, 213(1-2), 2001, pp. 135-142
Authors:
Frith, JC
Monkkonen, J
Auriola, S
Monkkonen, H
Rogers, MJ
Citation: Jc. Frith et al., The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate - Evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis, ARTH RHEUM, 44(9), 2001, pp. 2201-2210
Authors:
Ceponis, A
Waris, E
Monkkonen, J
Laasonen, L
Hyttinen, M
Solovieva, SA
Hanemaaijer, R
Bitsch, A
Konttinen, YT
Citation: A. Ceponis et al., Effects of low-dose, noncytotoxic, intraarticular liposomal clodronate on development of erosions and proteoglycan loss in established antigen-induced arthritis in rabbits, ARTH RHEUM, 44(8), 2001, pp. 1908-1916
Authors:
Monkkonen, H
Moilanen, P
Monkkonen, J
Frith, JC
Rogers, MJ
Auriola, S
Citation: H. Monkkonen et al., Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography-electrospray ionisation mass spectrometry, J CHROMAT B, 738(2), 2000, pp. 395-403
Authors:
Jaaskelainen, I
Peltola, S
Honkakoski, P
Monkkonen, J
Urtti, A
Citation: I. Jaaskelainen et al., A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioateoligonucleotides, EUR J PH SC, 10(3), 2000, pp. 187-193
Authors:
Kirjavainen, M
Urtti, A
Monkkonen, J
Hirvonen, J
Citation: M. Kirjavainen et al., Influence of lipids on the mannitol flux during transdermal iontophoresis in vitro, EUR J PH SC, 10(2), 2000, pp. 97-102
Authors:
Ezra, A
Hoffman, A
Breuer, E
Alferiev, IS
Monkkonen, J
El Hanany-Rozen, N
Weiss, G
Stepensky, D
Gati, I
Cohen, H
Tormalehto, S
Amidon, GL
Golomb, G
Citation: A. Ezra et al., A peptide prodrug approach for improving bisphosphonate oral absorption, J MED CHEM, 43(20), 2000, pp. 3641-3652
Authors:
Alatalo, SL
Halleen, JM
Hentunen, TA
Monkkonen, J
Vaananen, HK
Citation: Sl. Alatalo et al., Rapid screening method for osteoclast differentiation in vitro that measures tartrate-resistant acid phosphatase 5b activity secreted into the culture medium, CLIN CHEM, 46(11), 2000, pp. 1751-1754
Authors:
Qu, Q
Harkonen, PL
Monkkonen, J
Vaananen, HK
Citation: Q. Qu et al., Conditioned medium of estrogen-treated osteoblasts inhibits osteoclast maturation and function in vitro, BONE, 25(2), 1999, pp. 211-215
Authors:
Makkonen, N
Salminen, A
Rogers, MJ
Frith, JC
Urtti, A
Azhayeva, E
Monkkonen, J
Citation: N. Makkonen et al., Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite, EUR J PH SC, 8(2), 1999, pp. 109-118
Authors:
Cohen, H
Alferiev, IS
Monkkonen, J
Seibel, MJ
Pinto, T
Ezra, A
Solomon, V
Stepensky, D
Sagi, H
Ornoy, A
Patlas, N
Hagele, G
Hoffman, A
Breuer, E
Golomb, G
Citation: H. Cohen et al., Synthesis and preclinical pharmacology of 2-(2-aminopyrimidinio) ethylidene-1,1-bisphosphonic acid betaine (ISA-13-1) - A novel bisphosphonate, PHARM RES, 16(9), 1999, pp. 1399-1406
Authors:
Stensrud, G
Passi, S
Larsen, T
Sandset, PM
Smistad, G
Monkkonen, J
Karlsen, J
Citation: G. Stensrud et al., Toxicity of gamma irradiated liposomes. 1. In vitro interactions with blood components, INT J PHARM, 178(1), 1999, pp. 33-46
Authors:
Kirjavainen, M
Monkkonen, J
Saukkosaari, M
Valjakka-Koskela, R
Kiesvaara, J
Urtti, A
Citation: M. Kirjavainen et al., Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers, J CONTR REL, 58(2), 1999, pp. 207-214
Citation: Hl. Benford et al., Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: Biochemical evidence for two distinct pharmacological classes ofbisphosphonate drugs, MOLEC PHARM, 56(1), 1999, pp. 131-140