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Results: 1-25 | 26-28
Results: 1-25/28
PRESENTATIONS FROM THE 2ND NIH SYMPOSIUM ON THERAPEUTIC OLIGONUCLEOTIDES - INTRODUCTION
Authors: CHOCHUNG YS BEAUCAGE S BERGAN R MARQUEZ V NECKERS L TORRENCE PF
Citation: Ys. Chochung et al., PRESENTATIONS FROM THE 2ND NIH SYMPOSIUM ON THERAPEUTIC OLIGONUCLEOTIDES - INTRODUCTION, ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 8(2), 1998, pp. 113-114
P53 INHIBITS HYPOXIA-INDUCIBLE FACTOR-STIMULATED TRANSCRIPTION
Authors: BLAGOSKLONNY MV AN WG ROMANOVA LY TREPEL J FOJO T NECKERS L
Citation: Mv. Blagosklonny et al., P53 INHIBITS HYPOXIA-INDUCIBLE FACTOR-STIMULATED TRANSCRIPTION, The Journal of biological chemistry, 273(20), 1998, pp. 11995-11998
GELDANAMYCIN-STIMULATED DESTABILIZATION OF MUTATED P53 IS MEDIATED BYTHE PROTEASOME IN-VIVO
Authors: WHITESELL L SUTPHIN P AN WG SCHULTE T BLAGOSKLONNY MV NECKERS L
Citation: L. Whitesell et al., GELDANAMYCIN-STIMULATED DESTABILIZATION OF MUTATED P53 IS MEDIATED BYTHE PROTEASOME IN-VIVO, Oncogene, 14(23), 1997, pp. 2809-2816
DEPLETION OF P185(ERBB2), RAF-1 AND MUTANT P53 PROTEINS BY GELDANAMYCIN DERIVATIVES CORRELATES WITH ANTIPROLIFERATIVE ACTIVITY
Authors: AN WG SCHNUR RC NECKERS L BLAGOSKLONNY MV
Citation: Wg. An et al., DEPLETION OF P185(ERBB2), RAF-1 AND MUTANT P53 PROTEINS BY GELDANAMYCIN DERIVATIVES CORRELATES WITH ANTIPROLIFERATIVE ACTIVITY, Cancer chemotherapy and pharmacology, 40(1), 1997, pp. 60-64
INHIBITION OF EWS-FLI-1 FUSION PROTEIN WITH ANTISENSE OLIGODEOXYNUCLEOTIDES
Authors: TORETSKY JA CONNELL Y NECKERS L BHAT NK
Citation: Ja. Toretsky et al., INHIBITION OF EWS-FLI-1 FUSION PROTEIN WITH ANTISENSE OLIGODEOXYNUCLEOTIDES, Journal of neuro-oncology, 31(1-2), 1997, pp. 9-16
GENISTEIN-INDUCED APOPTOSIS OF PROSTATE-CANCER CELLS IS PRECEDED BY ASPECIFIC DECREASE IN FOCAL ADHESION KINASE-ACTIVITY
Authors: KYLE E NECKERS L TAKIMOTO C CURT G BERGAN R
Citation: E. Kyle et al., GENISTEIN-INDUCED APOPTOSIS OF PROSTATE-CANCER CELLS IS PRECEDED BY ASPECIFIC DECREASE IN FOCAL ADHESION KINASE-ACTIVITY, Molecular pharmacology, 51(2), 1997, pp. 193-200
RAF-1 BCL-2 PHOSPHORYLATION - A STEP FROM MICROTUBULE DAMAGE TO CELL-DEATH/
Authors: BLAGOSKLONNY MV GIANNAKAKOU P ELDEIRY WS KINGSTON DGI HIGGS PI NECKERS L FOJO T
Citation: Mv. Blagosklonny et al., RAF-1 BCL-2 PHOSPHORYLATION - A STEP FROM MICROTUBULE DAMAGE TO CELL-DEATH/, Cancer research, 57(1), 1997, pp. 130-135
RAPID DEUBIQUITINATION OF NUCLEOSOMAL HISTONES IN HUMAN TUMOR-CELLS CAUSED BY PROTEASOME INHIBITORS AND STRESS-RESPONSE INDUCERS - EFFECTS ON REPLICATION, TRANSCRIPTION, TRANSLATION, AND THE CELLULAR STRESS-RESPONSE
Authors: MIMNAUGH EG CHEN HY DAVIE JR CELIS JE NECKERS L
Citation: Eg. Mimnaugh et al., RAPID DEUBIQUITINATION OF NUCLEOSOMAL HISTONES IN HUMAN TUMOR-CELLS CAUSED BY PROTEASOME INHIBITORS AND STRESS-RESPONSE INDUCERS - EFFECTS ON REPLICATION, TRANSCRIPTION, TRANSLATION, AND THE CELLULAR STRESS-RESPONSE, Biochemistry, 36(47), 1997, pp. 14418-14429
GENISTEIN-STIMULATED ADHERENCE OF PROSTATE-CANCER CELLS IS ASSOCIATEDWITH THE BINDING OF FOCAL ADHESION KINASE TO BETA-1-INTEGRIN
Authors: BERGAN R KYLE E NGUYEN P TREPEL J INGUI C NECKERS L
Citation: R. Bergan et al., GENISTEIN-STIMULATED ADHERENCE OF PROSTATE-CANCER CELLS IS ASSOCIATEDWITH THE BINDING OF FOCAL ADHESION KINASE TO BETA-1-INTEGRIN, Clinical & experimental metastasis, 14(4), 1996, pp. 389-398
MUTANT CONFORMATION OF P53 TRANSLATED IN-VITRO OR IN-VIVO REQUIRES FUNCTIONAL HSP90
Authors: BLAGOSKLONNY MV TORETSKY J BOHEN S NECKERS L
Citation: Mv. Blagosklonny et al., MUTANT CONFORMATION OF P53 TRANSLATED IN-VITRO OR IN-VIVO REQUIRES FUNCTIONAL HSP90, Proceedings of the National Academy of Sciences of the United Statesof America, 93(16), 1996, pp. 8379-8383
P185(ERBB2) BINDS TO GRP94 IN-VIVO - DISSOCIATION OF THE P185(ERBB2) GRP94 HETEROCOMPLEX BY BENZOAUINONE ANSAMYCINS PRECEDES DEPLETION OF P185(ERBB2)/
Authors: CHAVANY C MIMNAUGH E MILLER P BITTON R NGUYEN P TREPEL J WHITESELL L SCHNUR R MOYER JD NECKERS L
Citation: C. Chavany et al., P185(ERBB2) BINDS TO GRP94 IN-VIVO - DISSOCIATION OF THE P185(ERBB2) GRP94 HETEROCOMPLEX BY BENZOAUINONE ANSAMYCINS PRECEDES DEPLETION OF P185(ERBB2)/, The Journal of biological chemistry, 271(9), 1996, pp. 4974-4977
POLYUBIQUITINATION AND PROTEASOMAL DEGRADATION OF THE P185(C-ERBB-2) RECEPTOR PROTEIN-TYROSINE KINASE INDUCED BY GELDANAMYCIN
Authors: MIMNAUGH EG CHAVANY C NECKERS L
Citation: Eg. Mimnaugh et al., POLYUBIQUITINATION AND PROTEASOMAL DEGRADATION OF THE P185(C-ERBB-2) RECEPTOR PROTEIN-TYROSINE KINASE INDUCED BY GELDANAMYCIN, The Journal of biological chemistry, 271(37), 1996, pp. 22796-22801
ELECTROPORATION OF SYNTHETIC OLIGODEOXYNUCLEOTIDES - A NOVEL TECHNIQUE FOR EX-VIVO BONE-MARROW PURGING
Authors: BERGAN R HAKIM F SCHWARTZ GN KYLE E CEPADA R SZABO JM FOWLER D GRESS R NECKERS L
Citation: R. Bergan et al., ELECTROPORATION OF SYNTHETIC OLIGODEOXYNUCLEOTIDES - A NOVEL TECHNIQUE FOR EX-VIVO BONE-MARROW PURGING, Blood, 88(2), 1996, pp. 731-741
HOW DO ANTISENSE OLIGODEOXYNUCLEOTIDES INHIBIT THE GROWTH OF CHRONIC MYELOGENOUS LEUKEMIA-CELLS
Authors: BERGAN R NECKERS L
Citation: R. Bergan et L. Neckers, HOW DO ANTISENSE OLIGODEOXYNUCLEOTIDES INHIBIT THE GROWTH OF CHRONIC MYELOGENOUS LEUKEMIA-CELLS, Blood, 87(9), 1996, pp. 4019-4019
DETECTION OF (11-22)(Q24-Q12) TRANSLOCATION-BEARING CELLS IN PERIPHERAL-BLOOD PROGENITOR CELLS OF PATIENTS WITH EWINGS-SARCOMA FAMILY OF TUMORS
Authors: TORETSKY JA NECKERS L WEXLER LH
Citation: Ja. Toretsky et al., DETECTION OF (11-22)(Q24-Q12) TRANSLOCATION-BEARING CELLS IN PERIPHERAL-BLOOD PROGENITOR CELLS OF PATIENTS WITH EWINGS-SARCOMA FAMILY OF TUMORS, Journal of the National Cancer Institute, 87(5), 1995, pp. 385-386
INHIBITION OF PROTEIN-TYROSINE KINASE-ACTIVITY IN INTACT-CELLS BY THEAPTAMERIC ACTION OF OLIGODEOXYNUCLEOTIDES
Authors: BERGAN RC KYLE E CONNELL Y NECKERS L
Citation: Rc. Bergan et al., INHIBITION OF PROTEIN-TYROSINE KINASE-ACTIVITY IN INTACT-CELLS BY THEAPTAMERIC ACTION OF OLIGODEOXYNUCLEOTIDES, Antisense research and development, 5(1), 1995, pp. 33-38
GELDANAMYCIN SELECTIVELY DESTABILIZES AND CONFORMATIONALLY ALTERS MUTATED P53
Authors: BLAGOSKLONNY MV TORETSKY J NECKERS L
Citation: Mv. Blagosklonny et al., GELDANAMYCIN SELECTIVELY DESTABILIZES AND CONFORMATIONALLY ALTERS MUTATED P53, Oncogene, 11(5), 1995, pp. 933-939
CONTRIBUTION OF SEQUENCE AND PHOSPHOROTHIOATE CONTENT TO INHIBITION OF CELL-GROWTH AND ADHESION CAUSED BY C-MYC ANTISENSE OLIGOMERS
Authors: CHAVANY C CONNELL Y NECKERS L
Citation: C. Chavany et al., CONTRIBUTION OF SEQUENCE AND PHOSPHOROTHIOATE CONTENT TO INHIBITION OF CELL-GROWTH AND ADHESION CAUSED BY C-MYC ANTISENSE OLIGOMERS, Molecular pharmacology, 48(4), 1995, pp. 738-746
DISRUPTION OF THE RAF-1-HSP90 MOLECULAR-COMPLEX RESULTS IN DESTABILIZATION OF RAF-1 AND LOSS OF RAF-1-RAS ASSOCIATION
Authors: SCHULTE TW BLAGOSKLONNY MV INGUI C NECKERS L
Citation: Tw. Schulte et al., DISRUPTION OF THE RAF-1-HSP90 MOLECULAR-COMPLEX RESULTS IN DESTABILIZATION OF RAF-1 AND LOSS OF RAF-1-RAS ASSOCIATION, The Journal of biological chemistry, 270(41), 1995, pp. 24585-24588
TAXOL INDUCTION OF P21(WAF1) AND P53 REQUIRES C-RAF-1
Authors: BLAGOSKLONNY MV SCHULTE TW NGUYEN P MIMNAUGH EG TREPEL J NECKERS L
Citation: Mv. Blagosklonny et al., TAXOL INDUCTION OF P21(WAF1) AND P53 REQUIRES C-RAF-1, Cancer research, 55(20), 1995, pp. 4623-4626
INTERLEUKIN-6 ANTISENSE DEOXYOLIGONUCLEOTIDES INHIBIT BONE-RESORPTIONBY GIANT-CELLS FROM HUMAN GIANT-CELL TUMORS OF BONE
Authors: REDDY SV TAKAHASHI S DALLAS M WILLIAMS RE NECKERS L ROODMAN GD
Citation: Sv. Reddy et al., INTERLEUKIN-6 ANTISENSE DEOXYOLIGONUCLEOTIDES INHIBIT BONE-RESORPTIONBY GIANT-CELLS FROM HUMAN GIANT-CELL TUMORS OF BONE, Journal of bone and mineral research, 9(5), 1994, pp. 753-757
GENISTEIN - A PROTEIN-TYROSINE KINASE INHIBITOR INHIBITS THE GROWTH OF PROSTATE-CANCER CELLS
Authors: BERGAN RC KYLE E NECKERS L
Citation: Rc. Bergan et al., GENISTEIN - A PROTEIN-TYROSINE KINASE INHIBITOR INHIBITS THE GROWTH OF PROSTATE-CANCER CELLS, Journal of cellular biochemistry, 1994, pp. 251-251
APTAMERIC INHIBITION OF P210(BCR-ABL) TYROSINE KINASE AUTOPHOSPHORYLATION BY OLIGODEOXYNUCLEOTIDES OF DEFINED SEQUENCE AND BACKBONE STRUCTURE
Authors: BERGAN R CONNELL Y FAHMY B KYLE E NECKERS L
Citation: R. Bergan et al., APTAMERIC INHIBITION OF P210(BCR-ABL) TYROSINE KINASE AUTOPHOSPHORYLATION BY OLIGODEOXYNUCLEOTIDES OF DEFINED SEQUENCE AND BACKBONE STRUCTURE, Nucleic acids research, 22(11), 1994, pp. 2150-2154
STABILITY, CLEARANCE AND DISPOSITION OF INTRAVENTRICULARLY ADMINISTERED OLIGODEOXYNUCLEOTIDES - IMPLICATIONS FOR THERAPEUTIC APPLICATION WITHIN THE CENTRAL-NERVOUS-SYSTEM
Authors: NECKERS L CHAVANY C GESELOWITZ D FAHMY B WALBRIDGE S ALGER J WHITESELL L
Citation: L. Neckers et al., STABILITY, CLEARANCE AND DISPOSITION OF INTRAVENTRICULARLY ADMINISTERED OLIGODEOXYNUCLEOTIDES - IMPLICATIONS FOR THERAPEUTIC APPLICATION WITHIN THE CENTRAL-NERVOUS-SYSTEM, Journal of cellular biochemistry, 1993, pp. 189-189
PHARMACOKINETICS AND DISPOSITION OF OLIGONUCLEOTIDES INFUSED INTO THERAT CENTRAL-NERVOUS-SYSTEM
Authors: GESELOWITZ DA CHAVANY C FAHMY B WHITESELL L NECKERS L
Citation: Da. Geselowitz et al., PHARMACOKINETICS AND DISPOSITION OF OLIGONUCLEOTIDES INFUSED INTO THERAT CENTRAL-NERVOUS-SYSTEM, Journal of cellular biochemistry, 1993, pp. 207-207
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