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Results: 1-8 |
Results: 8
Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors
Authors: Parker, MH Ortwine, DF O'Brien, PM Lunney, EA Banotai, CA Mueller, WT McConnell, P Brouillette, CG
Citation: Mh. Parker et al., Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors, BIOORG MED, 10(21), 2000, pp. 2427-2430
Structure-activity relationships and pharmacokinetic analysis for a seriesof potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors
Authors: O'Brien, PM Ortwine, DF Pavlovsky, AG Picard, JA Sliskovic, DR Roth, BD Dyer, RD Johnson, LL Man, C Hallak, H
Citation: Pm. O'Brien et al., Structure-activity relationships and pharmacokinetic analysis for a seriesof potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors, J MED CHEM, 43(2), 2000, pp. 156-166
A rationalization of the acidic pH dependence for stromelysin-1 (matrix metalloproteinase-3) catalysis and inhibition
Authors: Johnson, LL Pavlovsky, AG Johnson, AR Janowicz, JA Man, CF Ortwine, DF Purchase, CF White, AD Hupe, DJ
Citation: Ll. Johnson et al., A rationalization of the acidic pH dependence for stromelysin-1 (matrix metalloproteinase-3) catalysis and inhibition, J BIOL CHEM, 275(15), 2000, pp. 11026-11033
X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity
Authors: Pavlovsky, AG Williams, MG Ye, QZ Ortwine, DF Purchase, CF White, AD Dhanaraj, V Roth, BD Johnson, LL Hupe, D Humblet, C Blundell, TL
Citation: Ag. Pavlovsky et al., X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity, PROTEIN SCI, 8(7), 1999, pp. 1455-1462
Design and synthesis of novel quinoxaline-2,3-dione AMPA/Gly(N) receptor antagonists: Amino acid derivatives
Authors: Nikam, SS Cordon, JJ Ortwine, DF Heimbach, TH Blackburn, AC Vartanian, MG Nelson, CB Schwarz, RD Boxer, PA Rafferty, MF
Citation: Ss. Nikam et al., Design and synthesis of novel quinoxaline-2,3-dione AMPA/Gly(N) receptor antagonists: Amino acid derivatives, J MED CHEM, 42(12), 1999, pp. 2266-2271
Effect of species differences on stromelysin-1 (MMP-3) inhibitor potency -An explanation of inhibitor selectivity using homology modeling and chimeric proteins
Authors: Johnson, LL Bornemeier, DA Janowicz, JA Chen, J Pavlovsky, AG Ortwine, DF
Citation: Ll. Johnson et al., Effect of species differences on stromelysin-1 (MMP-3) inhibitor potency -An explanation of inhibitor selectivity using homology modeling and chimeric proteins, J BIOL CHEM, 274(35), 1999, pp. 24881-24887
X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor
Authors: Dhanaraj, V Williams, MG Ye, QZ Molina, F Johnson, LL Ortwine, DF Pavlovsky, A Rubin, JR Skeean, RW White, AD Humblet, C Hupe, DJ Blundell, TL
Citation: V. Dhanaraj et al., X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor, CROAT CHEM, 72(2-3), 1999, pp. 575-591
Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry
Authors: Parker, MH Lunney, EA Ortwine, DF Pavlovsky, AG Humblet, C Brouillette, CG
Citation: Mh. Parker et al., Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry, BIOCHEM, 38(41), 1999, pp. 13592-13601
Risultati: 1-8 |