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Results: 1-14 |
Results: 14
2ND-GENERATION NON-NUCLEOSIDIC REVERSE-TRANSCRIPTASE INHIBITOR HBY097AND HIV-1 VIRAL LOAD
Authors: RUBSAMENWAIGMANN H HUGUENEL E PAESSENS A KLEIM JP WAINBERG MA SHAH A
Citation: H. Rubsamenwaigmann et al., 2ND-GENERATION NON-NUCLEOSIDIC REVERSE-TRANSCRIPTASE INHIBITOR HBY097AND HIV-1 VIRAL LOAD, Lancet, 349(9064), 1997, pp. 1517-1517
IN-VITRO SELECTION FOR DIFFERENT MUTATIONAL PATTERNS IN THE HIV-1 REVERSE-TRANSCRIPTASE USING HIGH AND LOW SELECTIVE PRESSURE OF THE NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR HBY-097
Authors: KLEIM JP WINKLER I ROSNER M KIRSCH R RUBSAMENWAIGMANN H PAESSENS A RIESS G
Citation: Jp. Kleim et al., IN-VITRO SELECTION FOR DIFFERENT MUTATIONAL PATTERNS IN THE HIV-1 REVERSE-TRANSCRIPTASE USING HIGH AND LOW SELECTIVE PRESSURE OF THE NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR HBY-097, Virology, 231(1), 1997, pp. 112-118
ANTIVIRAL PROFILE OF HBY-097, A NONNUCLEOSIDIC INHIBITOR OF HIV-1 RT IN A PHASE STUDY
Authors: RUBSAMENWAIGMANN H WAINBERG M HUGUENEL E SHAH A PAESSENS A KLEIM JP ROSNER M
Citation: H. Rubsamenwaigmann et al., ANTIVIRAL PROFILE OF HBY-097, A NONNUCLEOSIDIC INHIBITOR OF HIV-1 RT IN A PHASE STUDY, Experimental hematology, 24(9), 1996, pp. 377-377
DIFFERENT MUTATIONAL PATHWAYS OF THE HIV-1 RT GENE ARE DEFINED BY ALTERNATIVE EXPERIMENTAL PROTOCOLS APPLIED TO GENERATE IN-VITRO RESISTANCE OF HIV-1 TO HBY-097
Authors: RIESS G WINKLER I ROSNER M KIRSCH R RUBSAMENWAIGMANN H PAESSENS A KLEIM JP HOECHST AG
Citation: G. Riess et al., DIFFERENT MUTATIONAL PATHWAYS OF THE HIV-1 RT GENE ARE DEFINED BY ALTERNATIVE EXPERIMENTAL PROTOCOLS APPLIED TO GENERATE IN-VITRO RESISTANCE OF HIV-1 TO HBY-097, AIDS, 10, 1996, pp. 8-8
SELECTIVE PRESSURE OF A QUINOXALINE NONNUCLEOSIDE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) ON HIV-1 REPLICATION RESULTS IN THE EMERGENCE OF NUCLEOSIDE RT-INHIBITOR-SPECIFIC (RT LEU-74-]VAL OR ILE AND VAL-75-]LEU OR ILE) HIV-1 MUTANTS
Authors: KLEIM JP ROSNER M WINKLER I PAESSENS A KIRSCH R HSIOU Y ARNOLD E RIESS G
Citation: Jp. Kleim et al., SELECTIVE PRESSURE OF A QUINOXALINE NONNUCLEOSIDE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) ON HIV-1 REPLICATION RESULTS IN THE EMERGENCE OF NUCLEOSIDE RT-INHIBITOR-SPECIFIC (RT LEU-74-]VAL OR ILE AND VAL-75-]LEU OR ILE) HIV-1 MUTANTS, Proceedings of the National Academy of Sciences of the United Statesof America, 93(1), 1996, pp. 34-38
NUCLEOSIDE REVERSE-TRANSCRIPTASE (RT) INHIBITOR-SPECIFIC MUTATIONS WITHIN THE HIV-1 POL GENE SELECTED WITH A NONNUCLEOSIDE TYPE RT INHIBITOR
Authors: KLEIM JP ROSNER M WINKLER I PAESSENS A KIRSCH R HSIOU Y ARNOLD E RIESS G
Citation: Jp. Kleim et al., NUCLEOSIDE REVERSE-TRANSCRIPTASE (RT) INHIBITOR-SPECIFIC MUTATIONS WITHIN THE HIV-1 POL GENE SELECTED WITH A NONNUCLEOSIDE TYPE RT INHIBITOR, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 3-3
HBY 097, IN-VITRO ANTIVIRAL PROFILE AGAINST HIV-1 AND ACTIVITY IN COMBINATION WITH OTHER ANTI-HIV-DRUGS
Authors: RUBSAMENWAIGMANN H PAESSENS A BLUNCK M KLEIM JP RIESS G WINKLER I ROSNER M SCHNEWEIS KE VONBRIESEN H
Citation: H. Rubsamenwaigmann et al., HBY 097, IN-VITRO ANTIVIRAL PROFILE AGAINST HIV-1 AND ACTIVITY IN COMBINATION WITH OTHER ANTI-HIV-DRUGS, AIDS research and human retroviruses, 11, 1995, pp. 159-159
PRECLINICAL EVALUATION OF HBY-097, A NEW NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION
Authors: KLEIM JP BENDER R KIRSCH R MEICHSNER C PAESSENS A ROSNER M RUBSAMENWAIGMANN H KAISER R WICHERS M SCHNEWEIS KE WINKLER I RIESS G
Citation: Jp. Kleim et al., PRECLINICAL EVALUATION OF HBY-097, A NEW NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION, Antimicrobial agents and chemotherapy, 39(10), 1995, pp. 2253-2257
INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C(2)-SYMMETRICAL PHOSPHINIC ACID AMIDE
Authors: PEYMAN A WAGNER K BUDT KH SPANIG J RUPPERT D MEICHSNER C PAESSENS A
Citation: A. Peyman et al., INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C(2)-SYMMETRICAL PHOSPHINIC ACID AMIDE, Bioorganic & medicinal chemistry letters, 4(10), 1994, pp. 1191-1194
SPECTRUM OF ACTIVITY OF SOLUBLE INTERCELLULAR-ADHESION MOLECULE-1 AGAINST RHINOVIRUS REFERENCE STRAINS AND FIELD ISOLATES
Authors: OHLIN A HOOVERLITTY H SANDERSON G PAESSENS A JOHNSTON SL HOLGATE ST HUGUENEL E GREVE JM
Citation: A. Ohlin et al., SPECTRUM OF ACTIVITY OF SOLUBLE INTERCELLULAR-ADHESION MOLECULE-1 AGAINST RHINOVIRUS REFERENCE STRAINS AND FIELD ISOLATES, Antimicrobial agents and chemotherapy, 38(6), 1994, pp. 1413-1415
MUTATIONAL ANALYSIS OF RESIDUE-190 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE
Authors: KLEIM JP BENDER R KIRSCH R MEICHSNER C PAESSENS A RIESS G
Citation: Jp. Kleim et al., MUTATIONAL ANALYSIS OF RESIDUE-190 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE, Virology, 200(2), 1994, pp. 696-701
RESISTANCE PATTERN OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE TO QUINOXALINE S-2720
Authors: BALZARINI J KARLSSON A MEICHSNER C PAESSENS A RIESS G DECLERCQ E KLEIM JP
Citation: J. Balzarini et al., RESISTANCE PATTERN OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE TO QUINOXALINE S-2720, Journal of virology, 68(12), 1994, pp. 7986-7992
A QUINOXALINE DERIVATIVE WITH HIGH INHIBITORY ACTIVITY AGAINST HIV-1 DEFINES A NEW BINDING-SITE ON THE REVERSE-TRANSCRIPTASE
Authors: KLEIM JP BENDER R BILHARDT UM MEICHSNER C PAESSENS A REISS G ROSNER M WINKLER I
Citation: Jp. Kleim et al., A QUINOXALINE DERIVATIVE WITH HIGH INHIBITORY ACTIVITY AGAINST HIV-1 DEFINES A NEW BINDING-SITE ON THE REVERSE-TRANSCRIPTASE, Journal of cellular biochemistry, 1993, pp. 16-16
ACTIVITY OF A NOVEL QUINOXALINE DERIVATIVE AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE AND VIRAL REPLICATION
Authors: KLEIM JP BENDER R BILLHARDT UM MEICHSNER C RIESS G ROSNER M WINKLER I PAESSENS A
Citation: Jp. Kleim et al., ACTIVITY OF A NOVEL QUINOXALINE DERIVATIVE AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE AND VIRAL REPLICATION, Antimicrobial agents and chemotherapy, 37(8), 1993, pp. 1659-1664
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