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Results: 1-25 | 26-45
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ALTERATIONS IN PROTEIN AGGREGATION AND DEGRADATION DUE TO MILD AND SEVERE MISSENSE MUTATIONS (A104D, R157N) IN THE HUMAN PHENYLALANINE-HYDROXYLASE GENE (PAH)
Authors: WATERS PJ PARNIAK MA HEWSON AS SCRIVER CR
Citation: Pj. Waters et al., ALTERATIONS IN PROTEIN AGGREGATION AND DEGRADATION DUE TO MILD AND SEVERE MISSENSE MUTATIONS (A104D, R157N) IN THE HUMAN PHENYLALANINE-HYDROXYLASE GENE (PAH), Human mutation, 12(5), 1998, pp. 344-354
IN-VITRO EXPRESSION ANALYSIS OF MUTATIONS IN PHENYLALANINE-HYDROXYLASE - LINKING GENOTYPE TO PHENOTYPE AND STRUCTURE TO FUNCTION
Authors: WATERS PJ PARNIAK MA NOWACKI P SCRIVER CR
Citation: Pj. Waters et al., IN-VITRO EXPRESSION ANALYSIS OF MUTATIONS IN PHENYLALANINE-HYDROXYLASE - LINKING GENOTYPE TO PHENOTYPE AND STRUCTURE TO FUNCTION, Human mutation, 11(1), 1998, pp. 4-17
IN-VITRO EXPRESSION ANALYSIS OF MUTATIONS IN PHENYLALANINE-HYDROXYLASE - LINKING GENOTYPE TO PHENOTYPE AND STRUCTURE TO FUNCTION
Authors: WATERS PJ PARNIAK MA NOWACKI P SCRIVER CR
Citation: Pj. Waters et al., IN-VITRO EXPRESSION ANALYSIS OF MUTATIONS IN PHENYLALANINE-HYDROXYLASE - LINKING GENOTYPE TO PHENOTYPE AND STRUCTURE TO FUNCTION, Human mutation, 11(1), 1998, pp. 4-17
DEGRADATION RATES DIFFER BETWEEN MUTANT AND WILD-TYPE FORMS OF PHENYLALANINE-HYDROXYLASE EXPRESSED IN-VITRO
Authors: WATERS PJ SCRIVER CR PARNIAK MA
Citation: Pj. Waters et al., DEGRADATION RATES DIFFER BETWEEN MUTANT AND WILD-TYPE FORMS OF PHENYLALANINE-HYDROXYLASE EXPRESSED IN-VITRO, Biochemical Society transactions, 26(3), 1998, pp. 276-276
ENDOGENOUS REVERSE-TRANSCRIPTASE ASSAYS REVEAL SYNERGY BETWEEN COMBINATIONS OF THE M184V AND OTHER DRUG RESISTANCE-CONFERRING MUTATIONS IN INTERACTIONS WITH NUCLEOSIDE ANALOG TRIPHOSPHATES
Authors: QUAN YD GU ZX LI XG LIANG C PARNIAK MA WAINBERG MA
Citation: Yd. Quan et al., ENDOGENOUS REVERSE-TRANSCRIPTASE ASSAYS REVEAL SYNERGY BETWEEN COMBINATIONS OF THE M184V AND OTHER DRUG RESISTANCE-CONFERRING MUTATIONS IN INTERACTIONS WITH NUCLEOSIDE ANALOG TRIPHOSPHATES, Journal of Molecular Biology, 277(2), 1998, pp. 237-247
A PROLINE-TO-HISTIDINE SUBSTITUTION AT POSITION-225 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) SENSITIZES HIV-1 RT TO BHAP U-90152
Authors: PELEMANS H ESNOUF RM PARNIAK MA VANDAMME AM DECLERCQ E BALZARINI J
Citation: H. Pelemans et al., A PROLINE-TO-HISTIDINE SUBSTITUTION AT POSITION-225 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) SENSITIZES HIV-1 RT TO BHAP U-90152, Journal of General Virology, 79, 1998, pp. 1347-1352
PHENOTYPIC MECHANISM OF HIV-1 RESISTANCE TO 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT) - INCREASED POLYMERIZATION PROCESSIVITY AND ENHANCED SENSITIVITY TO PYROPHOSPHATE OF THE MUTANT VIRAL REVERSE-TRANSCRIPTASE
Authors: ARION D KAUSHIK N MCCORMICK S BORKOW G PARNIAK MA
Citation: D. Arion et al., PHENOTYPIC MECHANISM OF HIV-1 RESISTANCE TO 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT) - INCREASED POLYMERIZATION PROCESSIVITY AND ENHANCED SENSITIVITY TO PYROPHOSPHATE OF THE MUTANT VIRAL REVERSE-TRANSCRIPTASE, Biochemistry (Easton), 37(45), 1998, pp. 15908-15917
PHYSICOCHEMICAL AND BIOCHEMICAL-PROPERTIES OF 2',5'-LINKED RNA AND 2',5'-RNA-3',5'-RNA HYBRID DUPLEXES
Authors: WASNER M ARION D BORKOW G NORONHA A UDDIN AH PARNIAK MA DAMHA MJ
Citation: M. Wasner et al., PHYSICOCHEMICAL AND BIOCHEMICAL-PROPERTIES OF 2',5'-LINKED RNA AND 2',5'-RNA-3',5'-RNA HYBRID DUPLEXES, Biochemistry, 37(20), 1998, pp. 7478-7486
INHIBITORY POTENCY OF R-REGION SPECIFIC ANTISENSE OLIGONUCLEOTIDES AGAINST IN-VITRO DNA POLYMERIZATION AND TEMPLATE-SWITCHING REACTIONS CATALYZED BY HIV-1 REVERSE-TRANSCRIPTASE
Authors: BORKOW G ARION D NORONHA A SCARTOZZI M DAMHA MJ PARNIAK MA
Citation: G. Borkow et al., INHIBITORY POTENCY OF R-REGION SPECIFIC ANTISENSE OLIGONUCLEOTIDES AGAINST IN-VITRO DNA POLYMERIZATION AND TEMPLATE-SWITCHING REACTIONS CATALYZED BY HIV-1 REVERSE-TRANSCRIPTASE, International journal of biochemistry & cell biology, 29(11), 1997, pp. 1285-1295
INHIBITION OF CARBOXYPEPTIDASE A BY N-(4-T-BUTYLBENZOYL)-2-HYDROXY-1-NAPHTHALDEHYDE HYDRAZONE
Authors: LANTHIER CM PARNIAK MA DMITRIENKO GI
Citation: Cm. Lanthier et al., INHIBITION OF CARBOXYPEPTIDASE A BY N-(4-T-BUTYLBENZOYL)-2-HYDROXY-1-NAPHTHALDEHYDE HYDRAZONE, Bioorganic & medicinal chemistry letters, 7(12), 1997, pp. 1557-1562
COMPARATIVE-ANALYSIS OF PHENYLALANINE-HYDROXYLASE A104D MUTANT, ASSOCIATED WITH VARIANT PHENYLKETONURIA, AND WILD-TYPE ENZYME
Authors: WATERS PJ HEWSON AS SCRIVER CR TREACY EP MARTINEZ A KNAPPSKOG PM PARNIAK MA
Citation: Pj. Waters et al., COMPARATIVE-ANALYSIS OF PHENYLALANINE-HYDROXYLASE A104D MUTANT, ASSOCIATED WITH VARIANT PHENYLKETONURIA, AND WILD-TYPE ENZYME, Biochemical Society transactions, 25(2), 1997, pp. 362-362
THE ROLE OF PHENYLALANINE IN STRUCTURE-FUNCTION-RELATIONSHIPS OF PHENYLALANINE-HYDROXYLASE REVEALED BY RADIATION TARGET ANALYSIS
Authors: DAVIS MD PARNIAK MA KAUFMAN S KEMPNER E
Citation: Md. Davis et al., THE ROLE OF PHENYLALANINE IN STRUCTURE-FUNCTION-RELATIONSHIPS OF PHENYLALANINE-HYDROXYLASE REVEALED BY RADIATION TARGET ANALYSIS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(2), 1997, pp. 491-495
IDENTIFICATION OF SEQUENCES DOWNSTREAM OF THE PRIMER BINDING-SITE THAT ARE IMPORTANT FOR EFFICIENT REPLICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
Authors: LI XG LIANG C QUAN YD CHANDOK R LAUGHREA M PARNIAK MA KLEIMAN L WAINBERG MA
Citation: Xg. Li et al., IDENTIFICATION OF SEQUENCES DOWNSTREAM OF THE PRIMER BINDING-SITE THAT ARE IMPORTANT FOR EFFICIENT REPLICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1, Journal of virology, 71(8), 1997, pp. 6003-6010
EFFECT OF MUTATIONS IN THE NUCLEOCAPSID PROTEIN (NCP7) UPON PR160(GAG-POL) AND TRNA(LYS) INCORPORATION INTO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
Authors: HUANG Y KHORCHID A WANG J PARNIAK MA DARLIX JL WAINBERG MA KLEIMAN L
Citation: Y. Huang et al., EFFECT OF MUTATIONS IN THE NUCLEOCAPSID PROTEIN (NCP7) UPON PR160(GAG-POL) AND TRNA(LYS) INCORPORATION INTO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1, Journal of virology, 71(6), 1997, pp. 4378-4384
CHEMICAL BARRIERS TO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) INFECTION - RETROVIRUCIDAL ACTIVITY OF UC781, A THIOCARBOXANILIDE NONNUCLEOSIDE INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE
Authors: BORKOW G BARNARD J NGUYEN TM BELMONTE A WAINBERG MA PARNIAK MA
Citation: G. Borkow et al., CHEMICAL BARRIERS TO HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) INFECTION - RETROVIRUCIDAL ACTIVITY OF UC781, A THIOCARBOXANILIDE NONNUCLEOSIDE INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE, Journal of virology, 71(4), 1997, pp. 3023-3030
CHARACTERISTICS OF THE PRO225HIS MUTATION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE THAT APPEARS UNDER SELECTIVEPRESSURE OF DOSE-ESCALATING QUINOXALINE TREATMENT OF HIV-1
Authors: PELEMANS H ESNOUF R DUNKLER A PARNIAK MA VANDAMME AM KARLSSON A DECLERCQ E KLEIM JP BALZARINI J
Citation: H. Pelemans et al., CHARACTERISTICS OF THE PRO225HIS MUTATION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE THAT APPEARS UNDER SELECTIVEPRESSURE OF DOSE-ESCALATING QUINOXALINE TREATMENT OF HIV-1, Journal of virology, 71(11), 1997, pp. 8195-8203
EFFECTS OF MUTATIONS IN PR160(GAG-POL) UPON TRNA(LYS3) AND PR160(GAG-POL) INCORPORATION INTO HIV-1
Authors: MAK J KHORCHID A CAO Q HUANG Y LOWY I PARNIAK MA PRASAD VR WAINBERG MA KLEIMAN L
Citation: J. Mak et al., EFFECTS OF MUTATIONS IN PR160(GAG-POL) UPON TRNA(LYS3) AND PR160(GAG-POL) INCORPORATION INTO HIV-1, Journal of Molecular Biology, 265(4), 1997, pp. 419-431
THE THIOCARBOXANILIDE NONNUCLEOSIDE UC781 IS A TIGHT-BINDING INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE
Authors: BARNARD J BORKOW G PARNIAK MA
Citation: J. Barnard et al., THE THIOCARBOXANILIDE NONNUCLEOSIDE UC781 IS A TIGHT-BINDING INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE, Biochemistry, 36(25), 1997, pp. 7786-7792
INHIBITION OF THE RIBONUCLEASE-H AND DNA-POLYMERASE ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE BY N-(4-TERT-BUTYLBENZOYL)-2-HYDROXY-1-NAPHTHALDEHYDE HYDRAZONE
Authors: BORKOW G FLETCHER RS BARNARD J ARION D MOTAKIS D DMITRIENKO GI PARNIAK MA
Citation: G. Borkow et al., INHIBITION OF THE RIBONUCLEASE-H AND DNA-POLYMERASE ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE BY N-(4-TERT-BUTYLBENZOYL)-2-HYDROXY-1-NAPHTHALDEHYDE HYDRAZONE, Biochemistry, 36(11), 1997, pp. 3179-3185
ANALYSIS OF THE [C.470G-]A-C.471A-]C] (R157N) MUTATION IN HUMAN PHENYLALANINE-HYDROXYLASE BY IN-VITRO PROTEIN EXPRESSION IN 3 SYSTEMS - CORRELATION WITH IN-VIVO PHENYLALANINE OXIDATION AND PHENYLKETONURIA PHENOTYPE
Authors: WATERS PJ HEWSON AS PARNIAK MA CARTER K KAYAALP E LAFRAMBOISE R TREACY EP SCRIVER CR
Citation: Pj. Waters et al., ANALYSIS OF THE [C.470G-]A-C.471A-]C] (R157N) MUTATION IN HUMAN PHENYLALANINE-HYDROXYLASE BY IN-VITRO PROTEIN EXPRESSION IN 3 SYSTEMS - CORRELATION WITH IN-VIVO PHENYLALANINE OXIDATION AND PHENYLKETONURIA PHENOTYPE, American journal of human genetics, 61(4), 1997, pp. 1532-1532
SINGLE-STEP PURIFICATION OF RECOMBINANT WILD-TYPE AND MUTANT HIV-1 REVERSE-TRANSCRIPTASE
Authors: FLETCHER RS HOLLESCHAK G NAGY E ARION D BORKOW G GU ZX WAINBERG MA PARNIAK MA
Citation: Rs. Fletcher et al., SINGLE-STEP PURIFICATION OF RECOMBINANT WILD-TYPE AND MUTANT HIV-1 REVERSE-TRANSCRIPTASE, Protein expression and purification, 7(1), 1996, pp. 27-32
EFFECTIVENESS OF 3TC IN HIV CLINICAL-TRIALS MAY BE DUE IN PART TO THEM184V SUBSTITUTION IN 3TC-RESISTANT HIV-1 REVERSE-TRANSCRIPTASE
Authors: WAINBERG MA HSU M GU ZX BORKOW G PARNIAK MA
Citation: Ma. Wainberg et al., EFFECTIVENESS OF 3TC IN HIV CLINICAL-TRIALS MAY BE DUE IN PART TO THEM184V SUBSTITUTION IN 3TC-RESISTANT HIV-1 REVERSE-TRANSCRIPTASE, AIDS, 10, 1996, pp. 3-10
ENHANCED FIDELITY OF 3TC-SELECTED MUTANT HIV-1 REVERSE-TRANSCRIPTASE
Authors: WAINBERG MA DROSOPOULOS WC SALOMON H HSU M BORKOW G PARNIAK MA GU ZX SONG QB MANNE J ISLAM S CASTRIOTA G PRASAD VR
Citation: Ma. Wainberg et al., ENHANCED FIDELITY OF 3TC-SELECTED MUTANT HIV-1 REVERSE-TRANSCRIPTASE, Science, 271(5253), 1996, pp. 1282-1285
DIFFERENCES IN THE INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE DNA-POLYMERASE-ACTIVITY BY ANALOGS OF NEVIRAPINEAND -5''-(4''-AMINO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE] (TSAO)
Authors: ARION D FLETCHER RS BORKOW G CAMARASA MJ BALZARINI J DMITRIENKO GI PARNIAK MA
Citation: D. Arion et al., DIFFERENCES IN THE INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE DNA-POLYMERASE-ACTIVITY BY ANALOGS OF NEVIRAPINEAND -5''-(4''-AMINO-1'',2''-OXATHIOLE-2'',2''-DIOXIDE] (TSAO), Molecular pharmacology, 50(5), 1996, pp. 1057-1064
HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 NUCLEOCAPSID PROTEIN (NCP7) DIRECTS SPECIFIC INITIATION OF MINUS-STRAND DNA-SYNTHESIS PRIMED BY HUMAN TRNA(3)(LYS) IN-VITRO - STUDIES OF VIRAL-RNA MOLECULES MUTATED IN REGIONS THAT FLANK THE PRIMER BINDING-SITE
Authors: LI XG QUAN YD ARTS EJ LI Z PRESTON BD DEROCQUIGNY H ROQUES BP DARLIX JL KLEIMAN L PARNIAK MA WAINBERG MA
Citation: Xg. Li et al., HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 NUCLEOCAPSID PROTEIN (NCP7) DIRECTS SPECIFIC INITIATION OF MINUS-STRAND DNA-SYNTHESIS PRIMED BY HUMAN TRNA(3)(LYS) IN-VITRO - STUDIES OF VIRAL-RNA MOLECULES MUTATED IN REGIONS THAT FLANK THE PRIMER BINDING-SITE, Journal of virology, 70(8), 1996, pp. 4996-5004
Risultati: 1-25 | 26-45