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Results: 1-17 |
Results: 17
DISCOVERY OF POTENT NONPEPTIDE VITRONECTIN RECEPTOR (ALPHA(V)BETA(3))ANTAGONISTS
Authors: KEENAN RM MILLER WH KWON C ALI FE CALLAHAN JF CALVO RR HWANG SM KOPPLE KD PEISHOFF CE SAMANEN JM WONG AS YUAN CK HUFFMAN WF
Citation: Rm. Keenan et al., DISCOVERY OF POTENT NONPEPTIDE VITRONECTIN RECEPTOR (ALPHA(V)BETA(3))ANTAGONISTS, Journal of medicinal chemistry, 40(15), 1997, pp. 2289-2292
DESIGN AND EVALUATION OF SMALL PEPTIDES MAPPING THE EXPOSED SURFACE OF IL-8
Authors: THOMPSON SK VEBER DF JUREWICZ AJ PEISHOFF CE LEE JM WHITE JR
Citation: Sk. Thompson et al., DESIGN AND EVALUATION OF SMALL PEPTIDES MAPPING THE EXPOSED SURFACE OF IL-8, International journal of peptide & protein research, 47(3), 1996, pp. 214-218
POTENT, SELECTIVE, ORALLY-ACTIVE 3-OXO-1,4-BENZODIAZEPINE GPIIB IIIA INTEGRIN ANTAGONISTS/
Authors: SAMANEN JM ALI FE BARTON LS BONDINELL WE BURGESS JL CALLAHAN JF CALVO RR CHEN WT CHEN LC ERHARD K FEUERSTEIN G HEYS R HWANG SM JAKAS DR KEENAN RM KU TW KWON C LEE CP MILLER WH NEWLANDER KA NICHOLS A PARKER M PEISHOFF CE RHODES G ROSS S SHU A SIMPSON R TAKATA D YELLIN TO UZSINSKAS I VENSLAVSKY JW YUAN CK HUFFMAN WF
Citation: Jm. Samanen et al., POTENT, SELECTIVE, ORALLY-ACTIVE 3-OXO-1,4-BENZODIAZEPINE GPIIB IIIA INTEGRIN ANTAGONISTS/, Journal of medicinal chemistry, 39(25), 1996, pp. 4867-4870
D-N-[(1-BENZYL-1H-IMIDAZOL-5-YL)-ALKYL] AND L-N-[(1-BENZYL-1H-IMIDAZOL-5-YL)-ALKYL] ACIDS AS ANGIOTENSIN-II AT-1 ANTAGONISTS
Authors: HILL DT GIRARD GR WEINSTOCK J EDWARDS RM WEIDLEY EF OHLSTEIN E PEISHOFF CE BAKER E AIYAR N
Citation: Dt. Hill et al., D-N-[(1-BENZYL-1H-IMIDAZOL-5-YL)-ALKYL] AND L-N-[(1-BENZYL-1H-IMIDAZOL-5-YL)-ALKYL] ACIDS AS ANGIOTENSIN-II AT-1 ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(1), 1995, pp. 19-24
IDENTIFICATION OF RESIDUES IN MULTIPLE TRANSMEMBRANE DOMAINS OF THE ENDOTHELIN RECEPTOR IMPLICATED IN LIGAND-BINDING - EVIDENCE FOR THE OVERLAP OF PEPTIDE AND NONPEPTIDE LIGAND-BINDING SITES
Authors: LONGTON ED BRINKMANN JA FRIESEN WJ PULVINO TA PEISHOFF CE ELLIOTT JD LEE JA
Citation: Ed. Longton et al., IDENTIFICATION OF RESIDUES IN MULTIPLE TRANSMEMBRANE DOMAINS OF THE ENDOTHELIN RECEPTOR IMPLICATED IN LIGAND-BINDING - EVIDENCE FOR THE OVERLAP OF PEPTIDE AND NONPEPTIDE LIGAND-BINDING SITES, The FASEB journal, 9(6), 1995, pp. 1449-1449
POTENT NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS WHICH PRESENT AN ALTERNATIVE PHARMACOPHORE
Authors: KU TW MILLER WH BONDINELL WE ERHARD KF KEENAN RM NICHOLS AJ PEISHOFF CE SAMANEN JM WONG AS HUFFMAN WF
Citation: Tw. Ku et al., POTENT NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS WHICH PRESENT AN ALTERNATIVE PHARMACOPHORE, Journal of medicinal chemistry, 38(1), 1995, pp. 9-12
COMPARISON OF THE STRUCTURES OF THE ENDOTHELIN-A RECEPTOR ANTAGONISTSBQ123 AND N-METHYL LEUCINE BQ123 WITH THE CRYSTAL-STRUCTURE OF THE C-TERMINAL TAIL OF ENDOTHELIN-1
Authors: PEISHOFF CE JANES RW WALLACE BA
Citation: Ce. Peishoff et al., COMPARISON OF THE STRUCTURES OF THE ENDOTHELIN-A RECEPTOR ANTAGONISTSBQ123 AND N-METHYL LEUCINE BQ123 WITH THE CRYSTAL-STRUCTURE OF THE C-TERMINAL TAIL OF ENDOTHELIN-1, FEBS letters, 374(3), 1995, pp. 379-383
CONFORMATIONS OF CYCLIC PENTAPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS
Authors: BEAN JW PEISHOFF CE KOPPLE KD
Citation: Jw. Bean et al., CONFORMATIONS OF CYCLIC PENTAPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS, International journal of peptide & protein research, 44(3), 1994, pp. 223-232
SB-209670, A RATIONALLY DESIGNED POTENT NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONIST
Authors: OHLSTEIN EH NAMBI P DOUGLAS SA EDWARDS RM GELLAI M LAGO A LEBER JD COUSINS RD GAO AM FRAZEE JS PEISHOFF CE BEAN JW EGGLESTON DS ELSHOURBAGY NA KUMAR C LEE JA YUE TL LOUDEN C BROOKS DP WEINSTOCK J FEUERSTEIN G POSTE G RUFFOLO RR GLEASON JG ELLIOTT JD
Citation: Eh. Ohlstein et al., SB-209670, A RATIONALLY DESIGNED POTENT NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONIST, Proceedings of the National Academy of Sciences of the United Statesof America, 91(17), 1994, pp. 8052-8056
TYR-129 IS IMPORTANT TO THE PEPTIDE LIGAND AFFINITY AND SELECTIVITY OF HUMAN ENDOTHELIN TYPE-A RECEPTOR
Authors: LEE JA ELLIOTT JD SUTIPHONG JA FRIESEN WJ OHLSTEIN EH STADEL JM GLEASON JG PEISHOFF CE
Citation: Ja. Lee et al., TYR-129 IS IMPORTANT TO THE PEPTIDE LIGAND AFFINITY AND SELECTIVITY OF HUMAN ENDOTHELIN TYPE-A RECEPTOR, Proceedings of the National Academy of Sciences of the United Statesof America, 91(15), 1994, pp. 7164-7168
1,3-DIARYLINDAN-2-CARBOXYLIC ACIDS, POTENT AND SELECTIVE NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS
Authors: ELLIOTT JD LAGO MA COUSINS RD GAO AM LEBER JD ERHARD KF NAMBI P ELSHOURBAGY NA KUMAR C LEE JA BEAN JW DEBROSSE CW EGGLESTON DS BROOKS DP FEUERSTEIN G RUFFOLO RR WEINSTOCK J GLEASON JG PEISHOFF CE OHLSTEIN EH
Citation: Jd. Elliott et al., 1,3-DIARYLINDAN-2-CARBOXYLIC ACIDS, POTENT AND SELECTIVE NONPEPTIDE ENDOTHELIN RECEPTOR ANTAGONISTS, Journal of medicinal chemistry, 37(11), 1994, pp. 1553-1557
LYSINE-182 OF ENDOTHELIN-B RECEPTOR MODULATES AGONIST SELECTIVITY ANDANTAGONIST AFFINITY - EVIDENCE FOR THE OVER-LAP OF PEPTIDE AND NONPEPTIDE LIGAND-BINDING SITES
Authors: LEE JA BRINKMANN JA LONGTON ED PEISHOFF CE LAGO MA LEBER JD COUSINS RD GAO AM STADEL JM KUMAR CS OHLSTEIN EH GLEASON JG ELLIOTT JD
Citation: Ja. Lee et al., LYSINE-182 OF ENDOTHELIN-B RECEPTOR MODULATES AGONIST SELECTIVITY ANDANTAGONIST AFFINITY - EVIDENCE FOR THE OVER-LAP OF PEPTIDE AND NONPEPTIDE LIGAND-BINDING SITES, Biochemistry, 33(48), 1994, pp. 14543-14549
REFINEMENT OF A MOLECULAR-MODEL OF ANGIOTENSIN-II (AII) EMPLOYED IN THE DISCOVERY OF POTENT NONPEPTIDE ANTAGONISTS
Authors: SAMANEN JM PEISHOFF CE KEENAN RM WEINSTOCK J
Citation: Jm. Samanen et al., REFINEMENT OF A MOLECULAR-MODEL OF ANGIOTENSIN-II (AII) EMPLOYED IN THE DISCOVERY OF POTENT NONPEPTIDE ANTAGONISTS, Bioorganic & medicinal chemistry letters, 3(5), 1993, pp. 909-914
EXTRACELLULAR DOMAIN-III MUTATIONS OF HUMAN ETB RECEPTOR AFFECT SARAFOTOXIN-6C BUT NOT ENDOTHELIN BINDING
Authors: LEE JA ELLIOTT JD ELSHOURBAGY N GLEASON J MORRIS R PEISHOFF CE SATHE G STADEL J SUTIPHONG JA
Citation: Ja. Lee et al., EXTRACELLULAR DOMAIN-III MUTATIONS OF HUMAN ETB RECEPTOR AFFECT SARAFOTOXIN-6C BUT NOT ENDOTHELIN BINDING, The FASEB journal, 7(7), 1993, pp. 1153-1153
POTENT NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS .2. 1-(CARBOXYBENZYL)IMIDAZOLE-5-ACRYLIC ACIDS
Authors: KEENAN RM WEINSTOCK J FINKELSTEIN JA FRANZ RG GAITANOPOULOS DE GIRARD GR HILL DT MORGAN TM SAMANEN JM PEISHOFF CE TUCKER LM AIYAR N GRIFFIN E OHLSTEIN EH STACK EJ WEIDLEY EF EDWARDS RM
Citation: Rm. Keenan et al., POTENT NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS .2. 1-(CARBOXYBENZYL)IMIDAZOLE-5-ACRYLIC ACIDS, Journal of medicinal chemistry, 36(13), 1993, pp. 1880-1892
CONFORMATIONAL MOBILITY IN CYCLIC OLIGOPEPTIDES
Authors: KOPPLE KD BEAN JW BHANDARY KK BRIAND J DAMBROSIO CA PEISHOFF CE
Citation: Kd. Kopple et al., CONFORMATIONAL MOBILITY IN CYCLIC OLIGOPEPTIDES, Biopolymers, 33(7), 1993, pp. 1093-1099
DIRECT DESIGN OF A POTENT NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONIST BASED ON THE STRUCTURE AND CONFORMATION OF A HIGHLY CONSTRAINED CYCLIC RGD PEPTIDE
Authors: KU TW ALI FE BARTON LS BEAN JW BONDINELL WE BURGESS JL CALLAHAN JF CALVO RR CHEN LC EGGLESTON DS GLEASON JG HUFFMAN WF HWANG SM JAKAS DR KARASH CB KEENAN RM KOPPLE KD MILLER WH NEWLANDER KA NICHOLS A PARKER MF PEISHOFF CE SAMANEN JM UZINSKAS I VENSLAVSKY JW
Citation: Tw. Ku et al., DIRECT DESIGN OF A POTENT NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONIST BASED ON THE STRUCTURE AND CONFORMATION OF A HIGHLY CONSTRAINED CYCLIC RGD PEPTIDE, Journal of the American Chemical Society, 115(19), 1993, pp. 8861-8862
Risultati: 1-17 |