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Results: 1-19 |
Results: 19
IN-VITRO AND IN-VIVO EVALUATIONS OF INTESTINAL BARRIERS FOR THE ZWITTERION L-767,679 AND ITS CARBOXYL ESTER PRODRUG L-775,318 - ROLES OF EFFLUX AND METABOLISM
Authors: PRUEKSARITANONT T DELUNA P GORHAM LM MA B COHN D PANG JM XU X LEUNG K LIN JH
Citation: T. Prueksaritanont et al., IN-VITRO AND IN-VIVO EVALUATIONS OF INTESTINAL BARRIERS FOR THE ZWITTERION L-767,679 AND ITS CARBOXYL ESTER PRODRUG L-775,318 - ROLES OF EFFLUX AND METABOLISM, Drug metabolism and disposition, 26(6), 1998, pp. 520-527
ERYTHROMYCIN BREATH TEST (EBT) AND ORAL MIDAZOLAM (MDZ) CONCURRENTLY AS IN-VIVO PROBES FOR CYP3A ACTIVITY
Authors: MCCREA J PRUEKSARITANONT T GERTZ B CARIDES A GILLAN L ANTONELLO S BRUCKER MJ MILLERSTEIN C OSBORNE B WALDMAN S
Citation: J. Mccrea et al., ERYTHROMYCIN BREATH TEST (EBT) AND ORAL MIDAZOLAM (MDZ) CONCURRENTLY AS IN-VIVO PROBES FOR CYP3A ACTIVITY, Clinical pharmacology and therapeutics, 63(2), 1998, pp. 68-68
EFFECTS OF PENTOBARBITAL ON PHARMACOKINETICS AND PHARMACODYNAMICS OF A POTENT FIBRINOGEN RECEPTOR ANTAGONIST, L-734217, IN DOGS
Authors: PRUEKSARITANONT T STRANIERI MT HAND EL ELLIS JD HOLAHAN MA SITKO GR COOK JJ
Citation: T. Prueksaritanont et al., EFFECTS OF PENTOBARBITAL ON PHARMACOKINETICS AND PHARMACODYNAMICS OF A POTENT FIBRINOGEN RECEPTOR ANTAGONIST, L-734217, IN DOGS, Biopharmaceutics & drug disposition, 18(8), 1997, pp. 649-663
IN-VITRO AND IN-VIVO EVALUATIONS OF THE METABOLISM, PHARMACOKINETICS,AND BIOAVAILABILITY OF ESTER PRODRUGS OF L-767,679, A POTENT FIBRINOGEN RECEPTOR ANTAGONIST - AN APPROACH FOR THE SELECTION OF A PRODRUG CANDIDATE
Authors: PRUEKSARITANONT T GORHAM LM BRESLIN MJ HUTCHINSON JH HARTMAN GD VYAS KP BAILLIE TA
Citation: T. Prueksaritanont et al., IN-VITRO AND IN-VIVO EVALUATIONS OF THE METABOLISM, PHARMACOKINETICS,AND BIOAVAILABILITY OF ESTER PRODRUGS OF L-767,679, A POTENT FIBRINOGEN RECEPTOR ANTAGONIST - AN APPROACH FOR THE SELECTION OF A PRODRUG CANDIDATE, Drug metabolism and disposition, 25(8), 1997, pp. 978-984
DISPOSITION OF L-738,167, A POTENT AND LONG-ACTING FIBRINOGEN RECEPTOR ANTAGONIST, IN DOGS - DOSE-DEPENDENT PHARMACOKINETICS
Authors: PRUEKSARITANONT T GORHAM LM NAUE JA HAMILL TG ASKEW BC VYAS KP
Citation: T. Prueksaritanont et al., DISPOSITION OF L-738,167, A POTENT AND LONG-ACTING FIBRINOGEN RECEPTOR ANTAGONIST, IN DOGS - DOSE-DEPENDENT PHARMACOKINETICS, Drug metabolism and disposition, 25(3), 1997, pp. 355-361
IN-VITRO METABOLISM OF SIMVASTATIN IN HUMANS [SBT]IDENTIFICATION OF METABOLIZING ENZYMES AND EFFECT OF THE DRUG ON HEPATIC P450S
Authors: PRUEKSARITANONT T GORHAM LM MA B LIU LD YU X ZHAO JGJ SLAUGHTER DE ARISON BH VYAS KP
Citation: T. Prueksaritanont et al., IN-VITRO METABOLISM OF SIMVASTATIN IN HUMANS [SBT]IDENTIFICATION OF METABOLIZING ENZYMES AND EFFECT OF THE DRUG ON HEPATIC P450S, Drug metabolism and disposition, 25(10), 1997, pp. 1191-1199
ANALYSIS OF METABOLITE KINETICS BY DECONVOLUTION AND IN VIVO-IN VITROCORRELATIONS OF METABOLITE FORMATION RATES - STUDIES OF FIBRINOGEN RECEPTOR ANTAGONIST ESTER PRODRUGS
Authors: PRUEKSARITANONT T GORHAM LM YEH KC
Citation: T. Prueksaritanont et al., ANALYSIS OF METABOLITE KINETICS BY DECONVOLUTION AND IN VIVO-IN VITROCORRELATIONS OF METABOLITE FORMATION RATES - STUDIES OF FIBRINOGEN RECEPTOR ANTAGONIST ESTER PRODRUGS, Journal of pharmaceutical sciences, 86(12), 1997, pp. 1345-1351
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/
Authors: ASKEW BC BEDNAR RA BEDNAR B CLAREMON DA COOK JJ MCINTYRE CJ HUNT CA GOULD RJ LYNCH RJ LYNCH JJ GAUL SL STRANIERI MT SITKO GR HOLAHAN MA GLASS JD HAMILL T GORHAM LM PRUEKSARITANONT T BALDWIN JJ HARTMAN GD
Citation: Bc. Askew et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/, Journal of medicinal chemistry, 40(12), 1997, pp. 1779-1788
COMPARATIVE-STUDIES OF DRUG-METABOLIZING-ENZYMES IN DOG, MONKEY, AND HUMAN SMALL-INTESTINES, AND IN CACO-2 CELLS
Authors: PRUEKSARITANONT T GORHAM LM HOCHMAN JH TRAN LO VYAS KP
Citation: T. Prueksaritanont et al., COMPARATIVE-STUDIES OF DRUG-METABOLIZING-ENZYMES IN DOG, MONKEY, AND HUMAN SMALL-INTESTINES, AND IN CACO-2 CELLS, Drug metabolism and disposition, 24(6), 1996, pp. 634-642
SPECIES AND ORGAN DIFFERENCES IN FIRST-PASS METABOLISM OF THE ESTER PRODRUG L-751,164 IN DOGS AND MONKEYS - IN-VIVO AND IN-VITRO STUDIES
Authors: PRUEKSARITANONT T GORHAM LM ELLIS JD FERNANDEZMETZLER C DELUNA P GEHRET JR STRONG KL HOCHMAN JH ASKEW BC DUGGAN ME GILBERT JD LIN JH VYAS KP
Citation: T. Prueksaritanont et al., SPECIES AND ORGAN DIFFERENCES IN FIRST-PASS METABOLISM OF THE ESTER PRODRUG L-751,164 IN DOGS AND MONKEYS - IN-VIVO AND IN-VITRO STUDIES, Drug metabolism and disposition, 24(11), 1996, pp. 1263-1271
IMMUNOPHARMACODYNAMIC STUDIES OF CYCLOSPORINE IN PATIENTS AWAITING RENAL-TRANSPLANTATION
Authors: DUSCIO CH AWEEKA FT PRUEKSARITANONT T TOMLANOVICH SJ GUPTA SK LANTZ MV GAMBERTOGLIO JG GAROVOY MR BENET LZ
Citation: Ch. Duscio et al., IMMUNOPHARMACODYNAMIC STUDIES OF CYCLOSPORINE IN PATIENTS AWAITING RENAL-TRANSPLANTATION, Journal of clinical pharmacology, 35(10), 1995, pp. 967-973
SPECIES-DIFFERENCES IN THE METABOLISM OF A POTENT HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR L-738,372 - IN-VIVO AND IN-VITRO STUDIES IN RATS, DOGS, MONKEYS, AND HUMANS
Authors: PRUEKSARITANONT T BALANI SK DWYER LM ELLIS JD KAUFFMAN LR VARGA SL PITZENBERGER SM THEOHARIDES AD
Citation: T. Prueksaritanont et al., SPECIES-DIFFERENCES IN THE METABOLISM OF A POTENT HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR L-738,372 - IN-VIVO AND IN-VITRO STUDIES IN RATS, DOGS, MONKEYS, AND HUMANS, Drug metabolism and disposition, 23(7), 1995, pp. 688-695
(-BUFURALOL 1'-HYDROXYLATION ACTIVITY IN HUMAN AND RHESUS-MONKEY INTESTINE AND LIVER())
Authors: PRUEKSARITANONT T DWYER LM CRIBB AE
Citation: T. Prueksaritanont et al., (-BUFURALOL 1'-HYDROXYLATION ACTIVITY IN HUMAN AND RHESUS-MONKEY INTESTINE AND LIVER()), Biochemical pharmacology, 50(9), 1995, pp. 1521-1525
HPLC ASSAY FOR FK-506 AND 2 METABOLITES IN ISOLATED RAT HEPATOCYTES AND RAT-LIVER MICROSOMES
Authors: PEROTTI BYT PRUEKSARITANONT T BENET LZ
Citation: Byt. Perotti et al., HPLC ASSAY FOR FK-506 AND 2 METABOLITES IN ISOLATED RAT HEPATOCYTES AND RAT-LIVER MICROSOMES, Pharmaceutical research, 11(6), 1994, pp. 844-847
PHARMACOKINETICS OF ORALLY AND INTRAVENOUSLY ADMINISTERED CYCLOSPORINE IN PRE-KIDNEY TRANSPLANT PATIENTS
Authors: AWEEKA FT TOMLANOVICH SJ PRUEKSARITANONT T GUPTA SK BENET LZ
Citation: Ft. Aweeka et al., PHARMACOKINETICS OF ORALLY AND INTRAVENOUSLY ADMINISTERED CYCLOSPORINE IN PRE-KIDNEY TRANSPLANT PATIENTS, Journal of clinical pharmacology, 34(1), 1994, pp. 60-67
IN-VITRO METABOLISM OF L-696,229, AN HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR IN RATS AND HUMANS - HEPATIC AND EXTRAHEPATIC METABOLISM AND IDENTIFICATION OF ENZYMES INVOLVED IN THE HEPATIC-METABOLISM
Authors: PRUEKSARITANONT T DWYER LM BALANI SK THEOHARIDES AD
Citation: T. Prueksaritanont et al., IN-VITRO METABOLISM OF L-696,229, AN HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR IN RATS AND HUMANS - HEPATIC AND EXTRAHEPATIC METABOLISM AND IDENTIFICATION OF ENZYMES INVOLVED IN THE HEPATIC-METABOLISM, Drug metabolism and disposition, 22(2), 1994, pp. 281-288
FK-506 METABOLISM IN MALE AND FEMALE RAT-LIVER MICROSOMES
Authors: PEROTTI BYT OKUDAIRA N PRUEKSARITANONT T BENET LZ
Citation: Byt. Perotti et al., FK-506 METABOLISM IN MALE AND FEMALE RAT-LIVER MICROSOMES, Drug metabolism and disposition, 22(1), 1994, pp. 85-89
THE EFFECT OF FLUCONAZOLE (F) ON THE PHARMACOKINETIC (PK) DISPOSITIONOF INTRAVENOUSLY ADMINISTERED CYCLOSPORINE (CYA) AND ITS METABOLITES IN RENAL-TRANSPLANT RECIPIENTS
Authors: LIM J AWEEKA F TSUNODA S PRUEKSARITANONT T TOMLANOVICH S BENET LZ
Citation: J. Lim et al., THE EFFECT OF FLUCONAZOLE (F) ON THE PHARMACOKINETIC (PK) DISPOSITIONOF INTRAVENOUSLY ADMINISTERED CYCLOSPORINE (CYA) AND ITS METABOLITES IN RENAL-TRANSPLANT RECIPIENTS, Clinical pharmacology and therapeutics, 55(2), 1994, pp. 149-149
CYCLOSPORINE METABOLISM BY RAT-LIVER MICROSOMES - EVIDENCE FOR INVOLVEMENT OF ENZYME(S) OTHER THAN CYTOCHROMES P-450 3A
Authors: PRUEKSARITANONT T CORREIA MA RETTIE AE SWINNEY DC THOMAS PE BENET LZ
Citation: T. Prueksaritanont et al., CYCLOSPORINE METABOLISM BY RAT-LIVER MICROSOMES - EVIDENCE FOR INVOLVEMENT OF ENZYME(S) OTHER THAN CYTOCHROMES P-450 3A, Drug metabolism and disposition, 21(4), 1993, pp. 730-737
Risultati: 1-19 |