Authors:
O'Brien, PM
Ortwine, DF
Pavlovsky, AG
Picard, JA
Sliskovic, DR
Roth, BD
Dyer, RD
Johnson, LL
Man, C
Hallak, H
Citation: Pm. O'Brien et al., Structure-activity relationships and pharmacokinetic analysis for a seriesof potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors, J MED CHEM, 43(2), 2000, pp. 156-166
Authors:
Johnson, LL
Pavlovsky, AG
Johnson, AR
Janowicz, JA
Man, CF
Ortwine, DF
Purchase, CF
White, AD
Hupe, DJ
Citation: Ll. Johnson et al., A rationalization of the acidic pH dependence for stromelysin-1 (matrix metalloproteinase-3) catalysis and inhibition, J BIOL CHEM, 275(15), 2000, pp. 11026-11033
Authors:
Pavlovsky, AG
Williams, MG
Ye, QZ
Ortwine, DF
Purchase, CF
White, AD
Dhanaraj, V
Roth, BD
Johnson, LL
Hupe, D
Humblet, C
Blundell, TL
Citation: Ag. Pavlovsky et al., X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity, PROTEIN SCI, 8(7), 1999, pp. 1455-1462
Authors:
Johnson, LL
Bornemeier, DA
Janowicz, JA
Chen, J
Pavlovsky, AG
Ortwine, DF
Citation: Ll. Johnson et al., Effect of species differences on stromelysin-1 (MMP-3) inhibitor potency -An explanation of inhibitor selectivity using homology modeling and chimeric proteins, J BIOL CHEM, 274(35), 1999, pp. 24881-24887
Authors:
Parker, MH
Lunney, EA
Ortwine, DF
Pavlovsky, AG
Humblet, C
Brouillette, CG
Citation: Mh. Parker et al., Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry, BIOCHEM, 38(41), 1999, pp. 13592-13601